7ekp/1/1:A/1:B

Sequences

>7ekp-a1-m1-cA (length=396) [Search sequence]

GEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSW
TDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNSSGHCQYLP
PGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDLVGIP
GKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKI
SLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDP
DGGKMPKWTRVILLNWCAWFLRMKRDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACV
VDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA

>7ekp-a1-m1-cB (length=396) [Search sequence]

Structure information

PDB ID	7ekp (database links: RCSB PDB PDBe PDBj PDBsum)
Title	human alpha 7 nicotinic acetylcholine receptor bound to EVP-6124
Assembly ID	1
Resolution	2.85Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	171
Sequence identity between the two chains	1.0
PubMed citation	33958730

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P36544	P36544
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:7ekpA	BioLiP:7ekpB

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	7ekp-a1-m1-cA_7ekp-a1-m1-cB.pdb.gz

Full biological assembly

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Download:	7ekp-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

7eki/1/1:A/1:B 7eki/1/1:A/1:E 7eki/1/1:B/1:C 7eki/1/1:C/1:D 7eki/1/1:D/1:E 7ekp/1/1:A/1:E 7ekp/1/1:B/1:C 7ekp/1/1:C/1:D 7ekp/1/1:D/1:E 7ekt/1/1:A/1:B 7ekt/1/1:A/1:E 7ekt/1/1:B/1:C 7ekt/1/1:C/1:D 7ekt/1/1:D/1:E 7koo/1/1:A/1:B 7koo/1/1:A/1:E 7koo/1/1:B/1:C 7koo/1/1:C/1:D 7koo/1/1:D/1:E 7koq/1/1:A/1:B 7koq/1/1:A/1:E 7koq/1/1:B/1:C 7koq/1/1:C/1:D 7koq/1/1:D/1:E 7kox/1/1:A/1:B 7kox/1/1:A/1:E 7kox/1/1:B/1:C 7kox/1/1:C/1:D 7kox/1/1:D/1:E