7f3g/1/1:B/1:A

Sequences
>7f3g-a1-m1-cB (length=266) [Search sequence]
PATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQNEVSILRR
VKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYL
HSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAET
GYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKE
LITMMLLVDVDQRFSAVQVLEHPWVN
>7f3g-a1-m1-cA (length=273) [Search sequence]
SEEGFQIPATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKEHMIQN
EVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNL
ASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVA
PEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDN
VSDSAKELITMMLLVDVDQRFSAVQVLEHPWVN
Structure information
PDB ID 7f3g (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of DCLK1 kinase domain in complex with ruxolitinib
Assembly ID 1
Resolution 2.1Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 84
Sequence identity between the two chains 1.0
PubMed citation 34445192
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession O15075 O15075
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:7f3gB BioLiP:7f3gA
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black]   [White]  
Download: 7f3g-a1-m1-cB_7f3g-a1-m1-cA.pdb.gz
Full biological assembly
Color: [By chain]   [By residue index]  
Spin: [Spin off]   [Spin on]   [Reset]
Render: [Low quality]   [High quality]  
Background: [Black quality]   [White quality]  
Download: 7f3g-assembly1.cif.gz

[Back to Home]