7laf/1/1:B/1:A |
| >7laf-a1-m1-cB (length=655) [Search sequence] |
HMAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLTAGAEEDFQVTLPEDVGRVLL
LRVHKAAWFCRWFQLTPPGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEE
LQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLL
DRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNF
PVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSP
GCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLP
EVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSEL
IQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDES
VQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQF
DSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLG
TYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENSVSI |
| >7laf-a1-m1-cA (length=663) [Search sequence] |
SHMAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDFTAGAEEDFQVTLPEDVGR
VLLLRVHKAGPDAWFCRWFQLTPPRGGHLLFPCYQWLEGAGTLVLQEGTAKVSWADHHPV
LQQQRQEELQARQEMYQWKAYNPGWPHCLDEKTVEDLELNIKYSTAKNANFYLQAGSAFA
EMKIKGLLDRKGLWRSLNEMKRIFNFRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRR
CHYLPKNFPVTDAMVASVLGPGTSLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAP
MTLLYQSPGCGPLLPLAIQLSQTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTH
LLHSHLLPEVFTLATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGI
GIEGFSELIQRNMKQLNYSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIG
IYYPSDESVQDDRELQAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKH
AAVSAGQFDSCAWMPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKE
PGDQRPLGTYPDEHFTEEAPRRSIATFQSRLAQISRGIQERNQGLVLPYTYLDPPLIENS
VSI |
|
| PDB ID |
7laf (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
15-lipoxygenase-2 loop mutant bound to imidazole-based inhibitor |
| Assembly ID |
1 |
| Resolution |
2.44Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
58 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
34500187 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
B |
A |
| UniProt accession |
O15296 |
O15296 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:7lafB |
BioLiP:7lafA |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
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