7m66/2/1:D/1:C

Sequences

>7m66-a2-m1-cD (length=357) [Search sequence]

RFYQMSPEERLASLLNEGQISADTKKEFENTALSSQIANHMIENQISETEVPMGVGLHLT VDETDYLVPMATEEPSVIAALSNGAKIAQGFKTVNQQRLMRGQIVFYDVADPESLIDKLQ VREAEIFQQAELSYPSIVKRGGGLRDLQYRAFDESFVSVDFLVDVKDAMGANIVNAMLEG VAELFREWFAEQKILFSILSNYATESVVTMKTAIPVSRLSKGSNGREIAEKIVLASRYAS LDPYRAVTHNKGIMNGIEAVVLATGNDTRAVSASCHAFAVKEGRYQGLTSWTLDGEQLIG EISVPLALATVGGATKVLPKSQAAADLLAVTDAKELSRVVAAVGLAQNLAALRALVS

>7m66-a2-m1-cC (length=360) [Search sequence]

NSRFYQMSPEERLASLLNEGQISADTKKEFENTALSSQIANHMIENQISETEVPMGVGLH LTVDETDYLVPMATEEPSVIAALSNGAKIAQGFKTVNQQRLMRGQIVFYDVADPESLIDK LQVREAEIFQQAELSYPSIVKRGGGLRDLQYRAFDESFVSVDFLVDVKDAMGANIVNAML EGVAELFREWFAEQKILFSILSNYATESVVTMKTAIPVSRLSKGSNGREIAEKIVLASRY ASLDPYRAVTHNKGIMNGIEAVVLATGNDTRAVSASCHAFAVKEGRYQGLTSWTLDGEQL IGEISVPLALATVGGATKVLPKSQAAADLLAVTDAKELSRVVAAVGLAQNLAALRALVSE

Structure information

PDB ID	7m66 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Targeting Enterococcus faecalis HMG-CoA reductase with a novel non-statin inhibitor
Assembly ID	2
Resolution	2.25Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	368
Sequence identity between the two chains	1.0
PubMed citation	37012403

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	D	C
UniProt accession	A0A4U3MLJ4	A0A4U3MLJ4
Species	1351 (Enterococcus faecalis)	1351 (Enterococcus faecalis)
Function annotation	BioLiP:7m66D	BioLiP:7m66C

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 7m66-a2-m1-cD_7m66-a2-m1-cC.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 7m66-assembly2.cif.gz

Similar dimers

Other dimers with similar sequences and structures

7m1z/1/1:A/1:B 7m1z/2/1:D/1:C 7m3h/1/1:A/1:B 7m66/1/1:A/1:B