7md5/1/1:B/1:A

Sequences

>7md5-a1-m1-cB (length=562) [Search sequence]

HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDY
LLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIE
KNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTNCPATVINGQFVERCWTH
SHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPY
YHFQDWRCVNFSFCQDLHHKCKCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGKVCHL
LEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSY
ALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKL
CLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWP
PDFRDLLGFMLFYKEAPYQNVVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTL
VTFSDERRTYGAKSDIIYVQTD

>7md5-a1-m1-cA (length=682) [Search sequence]

Structure information

PDB ID	7md5 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Insulin receptor ectodomain dimer complexed with two IRPA-9 partial agonists
Assembly ID	1
Resolution	5.2Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	11
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	P06213	P06213
Species	9606 (Homo sapiens)	9606 (Homo sapiens)

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	7md5-a1-m1-cB_7md5-a1-m1-cA.pdb.gz

Full biological assembly

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Download:	7md5-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

6ce9/1/1:A/1:B 6ceb/1/1:B/1:A