7mgq/2/1:C/1:D |
| >7mgq-a2-m1-cC (length=598) [Search sequence] |
EAPIALLSVYDKTGLLPFAKSLKELGFRLLGSGGTAKMIREAGMEIEDVSNITKAPEMLG
GRVKTLHPAVHGGILSRDIPSDLADLATNKISPITLVVCNLYPFVLQTAKPDCTLAGAIE
EIDIGGVTLLRAAAKNHGRVSIISSPSDYETIVAELRAKGEVSAETRRGLAIKAFEDTKS
YDEAISDYFRKVYATPGVEEEMKAGAGVGYQRLGLRYGANPHQKPAQAFVEQGEMPIKVL
SGSPGYINLLDALNSWALVKELAAGLDLPAAASFKHVSPAGAAVGLPLDERAAKVFGVED
LKELSPLACAYARARGADRMSSFGDFIALSHTVDTPTAKIISREVSDGVIAPGYEPEALE
ILSKKKGGKYCVLQMDPTYVPPEIETRQVYGISLQQKRNDCKIDESLFKNVVTANKDLPK
SAVTDLVVATLALKYTQSNSVCYALNGTVIGLGAGQQSRIHCTRLAGDKADNWWLRHHPR
VLELPFKKGTKRADKANAIDLFVTGQAFEERAQWESLFETVPEPLTKEEREKHMKELTGV
ACASDAFFPFPDNVHRAKRSGATYLAAPSGSIMDKECIKAADESNLVFCHTDLRLFHH |
| >7mgq-a2-m1-cD (length=602) [Search sequence] |
EAPIALLSVYDKTGLLPFAKSLKELGFRLLGSGGTAKMIREAGMEIEDVSNITKAPEMLG
GRVKTLHPAVHGGILSRDIPSDLADLATNKISPITLVVCNLYPFVLQTAKPDCTLAGAIE
EIDIGGVTLLRAAAKNHGRVSIISSPSDYETIVAELRAKGEVSAETRRGLAIKAFEDTKS
YDEAISDYFRKVYATPGVEEEMKAGAGVGYQRLGLRYGANPHQKPAQAFVEQGEMPIKVL
SGSPGYINLLDALNSWALVKELAAGLDLPAAASFKHVSPAGAAVGLPLDERAAKVFGVED
LKELSPLACAYARARGADRMSSFGDFIALSHTVDTPTAKIISREVSDGVIAPGYEPEALE
ILSKKKGGKYCVLQMDPTYVPPEIETRQVYGISLQQKRNDCKIDESLFKNVVTANKDLPK
SAVTDLVVATLALKYTQSNSVCYALNGTVIGLGAGQQSRIHCTRLAGDKADNWWLRHHPR
VLELPFKKGTKRADKANAIDLFVTGQAFEAEGGERAQWESLFETVPEPLTKEEREKHMKE
LTGVACASDAFFPFPDNVHRAKRSGATYLAAPSGSIMDKECIKAADESNLVFCHTDLRLF
HH |
|
| PDB ID |
7mgq (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans |
| Assembly ID |
2 |
| Resolution |
2.67Å |
| Method of structure determination |
X-RAY DIFFRACTION |
| Number of inter-chain contacts |
425 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
36063996 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
C |
D |
| UniProt accession |
A0A225ZZG7 |
A0A225ZZG7 |
| Species |
5207 (Cryptococcus neoformans) |
5207 (Cryptococcus neoformans) |
| Function annotation |
BioLiP:7mgqC |
BioLiP:7mgqD |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
|
|
|
|