7mp3/1/1:B/1:A

Sequences

>7mp3-a1-m1-cB (length=97) [Search sequence]

QLWFHGRISREESQRLIGQQGLVDGLFLVRESPQGFVLSLCHLQKVKHYLILPSEEEGRL YFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCT

>7mp3-a1-m1-cA (length=102) [Search sequence]

IHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRQGFVLSLCHLQKVKHYLILPSE EEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCT

Structure information

PDB ID	7mp3 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Grb7-SH2 domain in complex with bicyclic peptide B8
Assembly ID	1
Resolution	2.55Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	22
Sequence identity between the two chains	0.99
PubMed citation	35625882

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	Q14451	Q14451
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:7mp3A

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 7mp3-a1-m1-cB_7mp3-a1-m1-cA.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 7mp3-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures	2qms/3/1:A/1:B 2qms/4/1:C/1:D 5tyi/1/1:A/1:B 5tyi/2/1:D/1:C 5u06/1/1:B/1:A 5u06/2/1:D/1:C 5u1q/1/1:A/1:B 5u1q/2/1:D/1:C
Other dimers with similar sequences but different poses	2qms/2/1:B/2:D 2qms/1/1:A/2:C