7mp6/1/1:A/1:B

Sequences

>7mp6-a1-m1-cA (length=1600) [Search sequence]

RPVEWVQAVVSRFDEQLPIKTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNKN LYLSQLIILDTLEKCLAGQPETMLVKQLLPEICHFLQHAAELRNSASGVLFSLSCNNFNA VFSRISTRLQELTVVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLE KAFWNWVENYPDEFTKLYQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEI IQDISKNNMNKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYISVIFLLVQSMV VDLKNLLFNPSKPFSVDLMIDCLVSCFRISPNQHFKICLASPSTFHYVLVNSLHRIITNL DWWPKIDAVYCHSVELRNMFGETLHKAVQGDLETRSYKYLLLSMVKLIHADPKLLLCNPG STAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWPVETFWEISSQMLFYICKK LTSSSTEILKWLREILICRNKFLLKNPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFR HLCEEADIRCGVPNYNTFMEFASVRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQA TKLILSLQEWINMTGFLCALGGVCLTPVSKFMDRLLSLMVCNHEKVGLQIRTNVKDLVGL ELSPALYPMLFNKLKNTISKFFDSQGQVLLDTNTQFVEQTIAIMKNLLDNHTEGSSEHLG QASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEY LTDWVMVKCLTRDLDQASMEAVVSLLAGLPLQPEGVELMEAKSQLFLKYFTLFMNLLNDC SGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGV PGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVS ISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQR VTAILDKLITMTINEKQMYPSIQAKIWGSLGQLLDVVLDSFIKTSAIKAEVMADTAVALA SGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAAH LPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSLP KFYLLFGISKVKSAAVIAFYERETFALTSLETVTEALLEIMEACMRDIPTCKWLDQWTEL AQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKYNSQVLIEATVI ALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDSLRIFNDKSP EEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVARTVRILHTL LTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSDPKIQALLLTVLATLVKYTTDEFDQ RILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEPQYQ TSYLQSFGFNGLWRFAGPFIPDYAELIVKFLDALIDTYLP

>7mp6-a1-m1-cB (length=1609) [Search sequence]

RPVEWVQAVVSRFDEQLPIKTHTKVSTEHNKECLINISKYKFSLVISGLTTILKNVNNKN LYLSQLIILDTLEKCLAGQPETMLVKQLLPEICHFLQHAAELRNSASGVLFSLSCNNFNA VFSRISTRLQELTVVDVHDIELLQYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLE KAFWNWVENYPDEFTKLYQTDMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEI IQDISKNNMNKKLFLDSLRKALAGHGGSRQLTESAAIACVKLCKASTYISVIFLLVQSMV VDLKNLLFNPSKPFSVDLMIDCLVSCFRISPNQHFKICLASPSTFHYVLVNSLHRIITNL DWWPKIDAVYCHSVELRNMFGETLHKAVQGDLETRSYKYLLLSMVKLIHADPKLLLCNPG STAELITGLVQLVPQSHMPEIAQEAMEALLVLHQLDSIDLWPVETFWEISSQMLFYICKK LTSSSTEILKWLREILICRNKFLLKNPICRQAQTKLEVALYMFLWNPDTEAVLVAMSCFR HLCEEADIRCGVPNYNTFMEFASVRAALQKRVMALLRRIEHPTAGNTEAWEDTHAKWEQA TKLILSLQEWINMTGFLCALGGVCLTPVSKFMDRLLSLMVCNHEKVGLQIRTNVKDLVGL ELSPALYPMLFNKLKNTISKFFDSQGQVLLDTNTQFVEQTIAIMKNLLDNHTEGSSEHLG QASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQLVEVMMARRDDLSFCQEMKFRNKMVEY LTDWVMVKCLTRDLDQASMEAVVSLLAGLPLQPEGVELMEAKSQLFLKYFTLFMNLLNDC SGMSRRLASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGV PGTLLNIALLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVS ISKTLAANEPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQR VTAILDKLITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEV MADTAVALASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSF NNSLDVAAHLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLR LSLTEFSLPKFYLLFGISKVKSAAVIAFYERETFALTSLETVTEALLEIMEACMRDIPTC KWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESCLKYNS QVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALLEQNLHTLDS LRIFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGYRHPSPAIVA RTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSDPKIQALLLTVLATLV KYTTDEFDQRILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQS VVYHEPQYQTSYLQSFGFNGLWRFAGPFIPDYAELIVKFLDALIDTYLP

Structure information

PDB ID	7mp6 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Neurofibromin homodimer
Assembly ID	1
Resolution	6.25Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	341
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P21359	P21359
Species	9606 (Homo sapiens)	9606 (Homo sapiens)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 7mp6-a1-m1-cA_7mp6-a1-m1-cB.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 7mp6-assembly1.cif.gz