7mqs/1/1:E/1:F |
| >7mqs-a1-m1-cE (length=806) [Search sequence] |
GEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLF
RVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNE
LCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTNCPATQFVERCWTHSHCQKVCP
TICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRC
VNFSFCQDLHHKCKCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEK
TIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSL
SFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEI
HKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRD
LLGFMLFYKEAPYQNVVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSD
ERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWER
QAEDSELFELDYCLKGLKLPSRQILKELEESSFRKTFEDYLHNVVFVPREEHRPFEKVVN
KESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFE
NNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSV
RIRATSLAGNGSWTEPTYFYVTDYLD |
| >7mqs-a1-m1-cF (length=811) [Search sequence] |
HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDY
LLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIE
KNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTNCPATVINGQFVERCWTH
SHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPY
YHFQDWRCVNFSFCQDLHHKCKNSRCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPC
PKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYL
KIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFF
HYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLR
WEPYWPPDFRDLLGFMLFYKEAPYQNVTEFSWTVVDIDPPLRSNDPKSQNHPGWLMRGLK
PWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKP
PSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRLEESSFRKTFEDYLHEEHRPF
EKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVT
HEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSP
GNYSVRIRATSLAGNGSWTEPTYFYVTDYLD |
|
| PDB ID |
7mqs (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
The insulin receptor ectodomain in complex with three venom hybrid insulin molecules - asymmetric conformation |
| Assembly ID |
1 |
| Resolution |
4.4Å |
| Method of structure determination |
ELECTRON MICROSCOPY |
| Number of inter-chain contacts |
73 |
| Sequence identity between the two chains |
0.985 |
| PubMed citation |
35289328 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
E |
F |
| UniProt accession |
P06213 |
P06213 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:7mqsE |
BioLiP:7mqsF |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
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Full biological assembly
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