7mtq/1/1:A/1:B

Sequences

>7mtq-a1-m1-cA (length=742) [Search sequence]

KVLTLEGDLVLGGLFPVHQKPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLG AHILDSCSKDTHALEQALDFVRASLPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYAS TSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELE ARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNA SFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFRE FWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLC DAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYR YQKVGYWAEGLTLDTSLIPWASAGPLPASRCSEPCLQNEVKSVQEVCCWLCIPCQYELDE FTCADCGLGWPNLTGCFELPQEYIRWDAWAVGPVTIACLGALATLFVLGVFVRHNATPVV KASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIA RSPASQVAICLALISGQLLIVVAWLVVEAPGTETAPERREVVTLRCNHRDASMLGSLAYN VLLILCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCV SVSLSGSVVLGCLFAPKLHIIL

>7mtq-a1-m1-cB (length=744) [Search sequence]

KVLTLEGDLVLGGLFPVHQKPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLG AHILDSCSKDTHALEQALDFVRASLPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYAS TSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELE ARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNA SFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFRE FWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLC DAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGGRYRY QKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPLQNEVKSVQPEVCCWLCIPQPYERL DEFTCADGLGPNASLTGCFELPQEYIRWGDWAVGPVTIACLGALATLFVLGVFVRHNTVV KASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIA RIFFISPASQVAICLALISGQLLIVVAWLVVEAPGTTAPEVVTLRCNHRDASMLGSLAYN VLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMC VSVSLSGSVVLGCLFAPKLHIILF

Structure information

PDB ID	7mtq (database links: RCSB PDB PDBe PDBj PDBsum)
Title	CryoEM Structure of Full-Length mGlu2 in Inactive-State Bound to Antagonist LY341495
Assembly ID	1
Resolution	3.65Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	32
Sequence identity between the two chains	0.98
PubMed citation	34194039

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	Q14416	Q14416
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:7mtqA	BioLiP:7mtqB

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 7mtq-a1-m1-cA_7mtq-a1-m1-cB.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 7mtq-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

4xas/1/1:B/1:A 4xaq/1/1:B/1:A 5cni/1/1:A/1:B 5cnj/1/1:A/1:B 7e9g/1/1:S/1:R 7epb/1/1:A/1:B 7mtr/1/1:B/1:A 7mts/1/1:B/1:A