7s63/1/1:B/1:D

Sequences

>7s63-a1-m1-cB (length=1420) [Search sequence]

KVQYALTIPALLKSGETQRACVNLIGYHQPLALSVVLEHQRVNISIFSEKVQPPHYFKCN KFMVPTVITNAPDFVTLSVSGGGEDIKDRKAVVIAPLNTICLIQMDKPVYKPGCKVRFRL ISLNTMLLPISEKYTAVYLEDPSGSRIAQWQNQESVGGVVQLEFPLISDAAPGSYTITAE GESCESARQGFTVDEYILPRFSVIVDPPNTISILDDILTLNVSAIYTYGQPVPGSVTIKC CREASSYYGRKGNCFKGNRGICTNITGELGPDGAFYGVVSLLPFQMGQSGFQMSLGVALT VTEEGTGIQVTHQFFIMITSQLATLIFDYDALKEFYKRGIPYLVKVILTDANDNPMANEQ VEVELAGKTIGAVLTDKEGRAEYAIDTSSFVQENFTVVVSYENPHQCYYTEWEGPDFPTA QHFVMRFYSETGSFLDIQGSSVELNCGQVHNISVRYILSLDGMGEGATTATFYYLAMSRA KIVQHGQRDVHLNQSKSGLFNIGLNVTSDLAPGAELIVYCILDLELIADTISLDIEKCFQ NQVSLSFSDDLGPTASNVSLNLSAAPGSLCGVKVIDSSLLLINPYESLSASGVYYSIPYL SLFGYNYGGFNLEEPEPPCEDPNTVIFCKGRYYLPVSSSTEGDTYQNLRRVGLVLGTSSK IRKPVVCGMEAKFSVPRKSSGESDFGSSLSNGHVETLRKNFSETFLWRLVSVDSEGQNTI TETVPDTITKWQGSMFCVSEKEGFGITKYSANFTSFLPFFVELSLPYSLTREEILVMKAF VSNYLEECIKIIVTLQPSADFEVIPQDVKQDQCICSGGRSSYSWNIIASSLGRISFIVSA ETTHIGASCDGPSDQSQSTRKDTVIQTILVQPEGIRKEETSSNLVCVEDSNVEMPINLTL PENIVQGSASAFVTFVGDVLGLPLSNLQNLLQMPYGCGEQNLARMAPIPYVLEYLNNTNQ LTDELLQTAVQFLNEGYYRQLRYKLPSGAYDAFWSSPSDGSSWLSAYTFKTFEKAKKYIY VDGKIQQQTLLYLQTSQKLDNGCFKAEGNLFMRQCGQERDLCFTAYLAIALLESNYSSGM TLLDDALGCLEAAMSSASTLYFKSYTVYVFTLVQNWEIRNTLLNELKSKVVSERGTLHWE REDKLGQEGIPLYYPNYSPAEVEITAYMLLSIAKGSDPTHDDLTYMAQISVWLIQQQNSY GGFRSTQDTVVALQALAFYAQLLFKSNAHHNVFLRSEYGDVGQLNLSEHNRLVVQRLQLP EVSGNYSISINGTGCCLVQSTIRYNIPVPKENSAFYVAADSVSKNCLNGVAYTITITVSV SYRGLRNETNMVIIDIQMLSGYQADYPSLRQLENSQQVSKTEEQDNHVFLYLNAVPLKTI QLSFKVLIGSRVLNVKSASVYVYDYYETGENGFASYSQPC

>7s63-a1-m1-cD (length=1420) [Search sequence]

KVQYALTIPALLKSGETQRACVNLIGYHQPLALSVVLEHQRVNISIFSEKVQPPHYFKCN KFMVPTVITNAPDFVTLSVSGGGEDIKDRKAVVIAPLNTICLIQMDKPVYKPGCKVRFRL ISLNTMLLPISEKYTAVYLEDPSGSRIAQWQNQESVGGVVQLEFPLISDAAPGSYTITAE GESCESARQGFTVDEYILPRFSVIVDPPNTISILDDILTLNVSAIYTYGQPVPGSVTIKC CREASSYYGRKGNCFKGNRGICTNITGELGPDGAFYGVVSLLPFQMGQSGFQMSLGVALT VTEEGTGIQVTHQFFIMITSQLATLIFDYDALKEFYKRGIPYLVKVILTDANDNPMANEQ VEVELAGKTIGAVLTDKEGRAEYAIDTSSFVQENFTVVVSYENPHQCYYTEWEGPDFPTA QHFVMRFYSETGSFLDIQGSSVELNCGQVHNISVRYILSLDGMGEGATTATFYYLAMSRA KIVQHGQRDVHLNQSKSGLFNIGLNVTSDLAPGAELIVYCILDLELIADTISLDIEKCFQ NQVSLSFSDDLGPTASNVSLNLSAAPGSLCGVKVIDSSLLLINPYESLSASGVYYSIPYL SLFGYNYGGFNLEEPEPPCEDPNTVIFCKGRYYLPVSSSTEGDTYQNLRRVGLVLGTSSK IRKPVVCGMEAKFSVPRKSSGESDFGSSLSNGHVETLRKNFSETFLWRLVSVDSEGQNTI TETVPDTITKWQGSMFCVSEKEGFGITKYSANFTSFLPFFVELSLPYSLTREEILVMKAF VSNYLEECIKIIVTLQPSADFEVIPQDVKQDQCICSGGRSSYSWNIIASSLGRISFIVSA ETTHIGASCDGPSDQSQSTRKDTVIQTILVQPEGIRKEETSSNLVCVEDSNVEMPINLTL PENIVQGSASAFVTFVGDVLGLPLSNLQNLLQMPYGCGEQNLARMAPIPYVLEYLNNTNQ LTDELLQTAVQFLNEGYYRQLRYKLPSGAYDAFWSSPSDGSSWLSAYTFKTFEKAKKYIY VDGKIQQQTLLYLQTSQKLDNGCFKAEGNLFMRQCGQERDLCFTAYLAIALLESNYSSGM TLLDDALGCLEAAMSSASTLYFKSYTVYVFTLVQNWEIRNTLLNELKSKVVSERGTLHWE REDKLGQEGIPLYYPNYSPAEVEITAYMLLSIAKGSDPTHDDLTYMAQISVWLIQQQNSY GGFRSTQDTVVALQALAFYAQLLFKSNAHHNVFLRSEYGDVGQLNLSEHNRLVVQRLQLP EVSGNYSISINGTGCCLVQSTIRYNIPVPKENSAFYVAADSVSKNCLNGVAYTITITVSV SYRGLRNETNMVIIDIQMLSGYQADYPSLRQLENSQQVSKTEEQDNHVFLYLNAVPLKTI QLSFKVLIGSRVLNVKSASVYVYDYYETGENGFASYSQPC

Structure information

PDB ID	7s63 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Native-form oocyte/egg Alpha-2-Macroglobulin (A2Moo) tetramer
Assembly ID	1
Resolution	4.12Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	68
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	D
UniProt accession	A0A1L8FIE8	A0A1L8FIE8
Species	8355 (Xenopus laevis)	8355 (Xenopus laevis)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 7s63-a1-m1-cB_7s63-a1-m1-cD.pdb.gz

Full biological assembly Download: 7s63-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures	7s63/1/1:A/1:C 7s64/1/1:A/1:C 7s64/1/1:B/1:D
Other dimers with similar sequences but different poses	7s63/1/1:C/1:D 7s63/1/1:A/1:B 7s64/1/1:A/1:B 7s64/1/1:C/1:D