7sl1/1/1:A/1:B

Sequences

>7sl1-a1-m1-cA (length=813) [Search sequence]

HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDY LLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIE KNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDVCPGTAKGKTNCPATVQFVERCW THSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTKCVACRNFYLDGQCVETCPP PYYHFQDWRCVNFSFCQDLHFKCRNSRKPGCHQYVIHNNKCIPECPSGYTMNSSNLMCTP CLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEE ISGFLKIRRSYALVSLSFFRKLHLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQ GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRTSFD KILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFSWTVVDIDPPQRSHPGWLMRGLKPW TQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPS DPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRTDSQILKELEESSFRKTFEDYLH NHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDI VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRL RGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTD

>7sl1-a1-m1-cB (length=813) [Search sequence]

HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDY LLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIE KNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDVCPGTAKGKTNCPATVQFVERCW THSHCQKVCPTICKSHGCTAEGLCCHKECLGNCSEPDDPTKCVACRNFYLDGQCVETCPP PYYHFQDWRCVNFSFCQDLHFKCRNSRKPGCHQYVIHNNKCIPECPSGYTMNSSNLMCTP CLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEE ISGFLKIRRSYALVSLSFFRKLHLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQ GKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSFIRTSFD KILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFSWTVVDIDPPQRSHPGWLMRGLKPW TQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPS DPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRTDSQILKELEESSFRKTFEDYLH NHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKADDI VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRL RGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTD

Structure information

PDB ID	7sl1 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E)
Assembly ID	1
Resolution	3.4Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	149
Sequence identity between the two chains	1.0
PubMed citation	35361965

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P15208	P15208
Species	10090 (Mus musculus)	10090 (Mus musculus)
Function annotation	BioLiP:7sl1A	BioLiP:7sl1B

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 7sl1-a1-m1-cA_7sl1-a1-m1-cB.pdb.gz

Full biological assembly Download: 7sl1-assembly1.cif.gz