7tym/1/1:A/1:B

Sequences

>7tym-a1-m1-cA (length=771) [Search sequence]

VEVCPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLF
RVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPALGAVLRGAVRVEKNQE
LCHLSTIDWGLLQPAPGANHIVGNKLGEECADVCPGVLGAAGEPCAKTTFSGHTDYRCWT
SSHCQRVCPCPHGMACTARGECCHTECLGGCSQPEDPRACVACRHLYFQGACLWACPPGT
YQYESWRCVTAERCASLHSSTFGIHQGSCLAQCPSGFTRNSSKECKVGTKTIDSIQAAQD
LVGCTHVEGSLILNLRQGYNLEPQLQHSLGLVETITGFLKIKHSFALVSLGFFKNLKLIR
GDAMVDGNYTLYVLDNQNLQQLGSWVAAGLTIPVGKIYFAFNPRLCLEHIYRLEEVTGTR
GRQNKAEINPRTNGDRATRTLRFVSNVTEADRILLRWERYEPLEARDLLSFIVYYKESPF
QNATEHSWNLLDVELPLSRTQEPGVTLASLKPWTQYAVFVRAITLTTGAQSPIVYLRTLP
AAPTVPQDVISTSNSSSHLLVRWKPPTQRNGNLTYYLVLWQRLAEDGDLYLNDYCHRGLR
LPTSNNDSFQKKFENFLHNDFEIQEDKVPRERAVLSGLRHFTEYRIDIHACNHAAHTVGC
SAATFVFARTMPHREADGIPGKVAWEASSKNSVLLRWLEPPDPNGLILKYEIKYRRLGEE
ATVLCVSRLRYAKFGGVHLALLPPGNYSARVRATSLAGNGSWTDSVAFYIL

>7tym-a1-m1-cB (length=771) [Search sequence]

Structure information

PDB ID	7tym (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry
Assembly ID	1
Resolution	3.4Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	94
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	B
UniProt accession	P14616	P14616
Species	9606 (Homo sapiens)	9606 (Homo sapiens)

3D structure

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Dimer structure: Chain 1 in red; Chain 2 in blue.

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Download:	7tym-a1-m1-cA_7tym-a1-m1-cB.pdb.gz

Full biological assembly

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Download:	7tym-assembly1.cif.gz