7v3p/1/1:A/1:B

Sequences
>7v3p-a1-m1-cA (length=807) [Search sequence]
EICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRV
AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLC
YLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMCEKTTINNEYNYRCWTTNRCQKMC
PSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWR
CVDRDFCANILSFVIHDGECMQECPSGFIRNGSQSMYCIPPKVCEEEKKTKTIDSVTSAQ
MLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLI
LGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGT
KGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYK
EAPFKNVTEYDGQSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHI
RGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQD
GYLYRHNYCSKDKIPIRKCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPREYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAK
>7v3p-a1-m1-cB (length=816) [Search sequence]
EICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKARSYRFPKLTVITEYLLLFRVAGL
ESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLS
TVDWSLILDAVSNNYIVGNKPPKECGDLCPGCEKTTINNEYNYRCWTTNRCQKMCPSTCG
KRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRD
FCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKT
IDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLS
FLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIY
RMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDL
ISFTVYYKEAPFKNVTEYDGQSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTL
TMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIV
RWQRQPQDGYLYRHNYCSKDKIPIRKCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVP
RPEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGA
DDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGA
KLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAK
Structure information
PDB ID 7v3p (database links: RCSB PDB PDBe PDBj PDBsum)
Title Cryo-EM structure of the IGF1R/insulin complex
Assembly ID 1
Resolution 3.6Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 71
Sequence identity between the two chains 0.994
PubMed citation
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID A B
UniProt accession P08069 P08069
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:7v3pB
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 7v3p-a1-m1-cA_7v3p-a1-m1-cB.pdb.gz
Full biological assembly
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Download: 7v3p-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences but different poses
  • 5u8r/1/1:A/2:A 5u8q/1/1:A/2:A
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