7zr5/1/1:B/1:A

Sequences
>7zr5-a1-m1-cB (length=631) [Search sequence]
EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK
ELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQF
GVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQ
TEYLEERRVKEVVKKHSQFIGYPITLYLEKEKEKYIDQEELNKTKPIWTRNPDDITQEEY
GEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVF
IMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAE
DKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQK
SIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGL
ELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTAN
MERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFET
ALLSSGFSLEDPQTHSNRIYRMIKLGLGIDE
>7zr5-a1-m1-cA (length=633) [Search sequence]
EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK
ELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQF
GVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQ
TEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEKYIDQEELNKTKPIWTRNPDDITQE
EYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRR
VFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSEL
AEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKET
QKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKE
GLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWT
ANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLF
ETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDE
Structure information
PDB ID 7zr5 (database links: RCSB PDB PDBe PDBj PDBsum)
Title CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(closed) complex
Assembly ID 1
Resolution 3.9Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 232
Sequence identity between the two chains 1.0
PubMed citation 36446791
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID B A
UniProt accession P08238 P08238
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
Function annotation BioLiP:7zr5B BioLiP:7zr5A
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
Download: 7zr5-a1-m1-cB_7zr5-a1-m1-cA.pdb.gz
Full biological assembly
Download: 7zr5-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 7zr0/1/1:B/1:A 7zr6/1/1:B/1:A

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