8b41/1/1:F/1:E

Sequences

>8b41-a1-m1-cF (length=195) [Search sequence]

AFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVEMKGLKTDLDLQQYSF INQMCYERALHWYAKYFPYLVLIHTLVFMLCSNFWFKFPGSSSKIEGDILYAMYVRQTVL KVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKNFSCNHTMAHLFSKLSFCYLCFVS IYGLTCLYTLYWLFY

>8b41-a1-m1-cE (length=254) [Search sequence]

AFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVEMKGLKTDLDLQQYSF INQMCYERALHWYAKYFPYLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSKV KKFRLHVEEGDILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDMTGYKN FSCNHTMAHLFSKLSFCYLCFVSIYGLTCLYTLYWLFYRSLREYDVKNDFAFMLHMIDQY DPLYSKRFAVFLSE

Structure information

PDB ID	8b41 (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Structure of heteromeric LRRC8A/C (1:1 co-transfected) Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Assembly ID	1
Resolution	3.8Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	65
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	F	E
UniProt accession	Q8R502	Q8R502
Species	10090 (Mus musculus)	10090 (Mus musculus)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 8b41-a1-m1-cF_8b41-a1-m1-cE.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 8b41-assembly1.cif.gz