8bem/2/1:D/1:B

Sequences

>8bem-a2-m1-cD (length=275) [Search sequence]

SMKQYEHVKRDLNPEDFWEIIGELGDGGKVYKAQNKETSVLAAAKVIDTKSEEELEDYMV EIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQ TLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGSFIGTPYWMAPEVVMCETPYDYK ADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEK NVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAE

>8bem-a2-m1-cB (length=277) [Search sequence]

SMKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVIDTKSEEELEDY MVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVC KQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGSFIGTPYWMAPEVVMCETPYD YKADVWSLGITLIEMAEIEPPHHELNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCL EKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAE

Structure information

PDB ID	8bem (database links: RCSB PDB PDBe PDBj PDBsum)
Title	STE20-like serine/threonine-protein kinase (SLK) in complex with Tivozanib
Assembly ID	2
Resolution	2.6Å
Method of structure determination	X-RAY DIFFRACTION
Number of inter-chain contacts	67
Sequence identity between the two chains	1.0
PubMed citation

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	D	B
UniProt accession	Q9H2G2	Q9H2G2
Species	9606 (Homo sapiens)	9606 (Homo sapiens)
Function annotation	BioLiP:8bemD	BioLiP:8bemB

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Download: 8bem-a2-m1-cD_8bem-a2-m1-cB.pdb.gz

Full biological assembly Download: 8bem-assembly2.cif.gz

Similar dimers

Other dimers with similar sequences but different poses

2j51/1/1:A/2:A 2jfl/1/1:A/2:A 2jfm/1/1:A/2:A 2uv2/1/1:A/2:A