8duj/1/1:A/1:G

Sequences

>8duj-a1-m1-cA (length=3823) [Search sequence]

QFLRTDDEVVLQCSAQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLEQSLSVR ALQEMLANTGHRTLLYGHAILLRHAHSRMYLSCLTTSRSMTDKLAFDVGLQEDATGEACW WTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLQVDASFMQTLWNMNPICYVTGGHVL RLFHGECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRIR HVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEGMGPPEIKYGESLCFVQHVASG LWLTYAALKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFIKGLDSFSGK PRALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQSLFQEEGMLSLVLNCID RLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLD RLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGV AVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVV PFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTS PGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFL LGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPPHLVGPSRCLSHTDFVPI VLPPHLERIREKLAENIHELWALTRIHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGC VDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVR TLLGYGYNIEPDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGAD ELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETA FREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWF SKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFH QHFRLNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMHSSLKCS NCYMVWGGDFVHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQ NVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRR AGERLGWAVQCQDPLTMMALHIPEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNN RVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLT PETRAITLFPRHGLPGVGVTTSLRPPHHFSPPCFVAALPPARLSPAIPLEALRDKALRML GEAVRDGGQHARDPVGGSVEFQFVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEE GLLQMKLPESVKLQMCNLLEYFCDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAF TMSAAETARRTREFRSPPQEQINMLLHFKDDCPLPEDIRQDLQDFHQDLLAHCGIQPQSL QELVSHMVVRWAQEDYVQSPELVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMS LLECLGQIRSLLIVQMGPQEENLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNV LGEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSMQGSTPLDVAAASVIDNN ELALALQEQDLEKVVSYLAGCGLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGE SVEENANVVVRLLIRKPECFGPALRGSGLLAAIEEAIRISEDPRVHLGHAIMSFYAALID LLGRCAPEMHLIQAGKGEALRIRAILRSLVPLDDLVGIISLPLQIPQPKMSASFVPDHKA SMVLFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTEMALALNRYLCLAVLPLITKCA PLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRL VFDVPILNEFAKMPLKLLTNHYEREEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLC AEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIYRW PIKESLKAMIAWEWTIEKAREGEEERTEKKKTRKISQTAQTYDPREGYNPQPPDLSGVTL SRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQELL KFLQMNGYAVTRFAFGFLQQLLRWMDISQEFIEIKFFAKILLPLINQYFTNHEKEMITSL FCKLAALAVVNCLHILAREIVKAGLRSFFESASEDIEKMVEGQNLTYTTVALLPVLTTLF QHIAQDVQVSCYRTLCSIYSLGTPALGECLARLPMLCSYLPRWWSDHLNSLLGNILRIIV NNMKRLAVFAQPLHSHFIPTIGRLRKRAGKVVAEEEQLRLEAKAEAEEGELLVRDEFSVL CRDLYALYPLLIRYVDNNRAHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQ VATLKKMLPIGLNQDLIMLAKTRYALKDTDEEVREEKIVRRVQEVSAVLYHLEQTEHSKQ RRRAVVACFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGKKPDPL HQLVLHFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEVSFEEKEMEKQRLLYQQSRLHT RGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSI QALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLC EGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFS KAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIEL LKELLDLQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIV GSEAFQDYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEINFEEFANRFQEPARD IGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEIS ETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISETAREA ATALAALLWAVVARWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSP PNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFD GLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMD LASLEITAHNERTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHL LDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPD MKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQ GLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLM YLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQL

>8duj-a1-m1-cG (length=3933) [Search sequence]

VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLE QSLSVRALQEMLANGHRTLLYGHAILLRHAHSRMYLSCLTTSRKLAFDVGLQEDATGEAC WWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTLQVDASFMQTLWNMNPICSCCE EGYVTGGHVLRLFHGECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISWSGSH LRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEMGPPEIKYGESL CFVQHVASGLWLTYAALKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAGLYNQFI KGLDSFSGKPRLPIEAVILSLQDLIGYFEPPQSKLRSLRNRQSLFQEEGMLSLVLNCIDR LNVYTTEEAAESWKEIVNLLYELLASLIRGNRANCALFSTNLDWVVSKLDRLEASSGILE VLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLDVLCSLCVCNGVAVRSNQDLIT ENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGSTQYGKWYFEVMVDEVVPFLTAQATHL RVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHLWTGHVARPVTSPGQHLLAPED VVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGLFFPVVSFSAGVKVRFLLGGRHGEFKF LPPPGYAPCHEAVLPRERLRLEPIKEYRREGPPHLVGPSRCLSHTDFVPIVLPPHLERIR EKLAENIHELWALTRIHPCLVNFHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAE DNLKKTKLPKTYMMSNGYKPAPLDLSHVRLTPAQTTLVDRLAENGHNVWARDRVAQGWSY SAVQDIPARRNPRLVPYRLLDEATKRSNRDSLCQAVRTLLGYGYNIEPDRVRIFRAEKSY TVQSGRWYFEFEAVTTGEMRVGWARPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGR PWQSGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGH LNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMD GTVDTPPCLRLAHRTWGSQNSLVEMLFLRLSLPVQFHQHFRILNTTTYYYSVRVFAGQEP SCVWVGWVTPDYHQHDMNFDLSKVRAVTVTMHSSLKCSNCYMVWGGDFVHTDLVIGCLVD LATGLMTFTANGKESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFL SERKNPAPQCPPRLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHI PEENRCMDILELSERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDA HLPGPLRAGYYDLLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPRHGLPGVGVTTS LRPPHHFSPPCFVAALPPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQ FVPVLKLVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEGLLQMKLPESVKLQMCNLLEYF CDQELQHRVESLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQI NMLLHFKDDCPLPEDIRQDLQDFHQDLLAHCGIQLPQSLQELVSHMVVRWAQEDYVQSPE LVRAMFSLLHRQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEE NLMIQSIGNIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGEIRFPKMVTSCCRFLCYFC RISRQNQRSMFDHLSYLLENSMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGC GLQSCPMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFG PALRGSGLLAAIEEAIRISEDPNRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEAL RIRAILRSLVPLDDLVGIISLPLQIPVQPKMSASFVPDHKASMVLFLDRVYGIENQDFLL HVLDVGFLPDMRAAASLDTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIMVDSMLHT VYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAKMPLKLLT NHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRMAMPCLCA IAPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFSEKDKEIY RWPIKESLKAMIAWEWTIEKAREGEEERTEKKKTRKISQTAQTYDPREGYNPQPPDLSGV TLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKAQE LLKFLQMNGYAVTRIEKRFAFGFLQQLLRWMDISQEFIAHLEAHEQEIKFFAKILLPLIN QYFTNHCLYFLSNKEKEMITSLFCKLAALVRHVVNCLHILARKAGLRSFFESASEDIEKM VENLRQNLTYTTVALLPVLTTLFQHIAQHDVQVSCYRTLCSIYSLRPALGECLARLAARL MADIGGLAPHVIEITLPMLCSYLPRWSDHLNSLLGNILRIIVNNRLAVFAQPIVSRARPE LLHSHFIPTIGRLRKRAGKVVAEEEQLRDEFSVLCRDLYALYPLLIRYVDNNRAHWLTEP NANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEIVATLKKMLPIGLNMCDQDLIMLA KTRYALKDTDEEVREFLQNDPEKIVRRVQEVSAVLYHLEQTEHSKQRRRAVVACFRMTPL YNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGKKPDPLHQLVLHFSRTALTE KSKLDEDYLYMAYADIMAKSCHLEEVSFEEKEMEKQRLLYQQSRLHTRGAAEMVLQMISA CKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQTCSVLDLN AFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNNDFQNYLRT QTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVAKQVFNSL TEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLDLQKDMVV MLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQDYVTDPR GLISKKDFQKAMDSQKQFTGPEIQFLLSCSEEMINFEEFANRFQEPARDIGFNVAVLLTN LSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEISETNRAQWEMPQ VKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISETAREAATALAALLWAV VARWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPNMVYYFLEES TGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFDGLYITEQPGDD DVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMDLASLEITAHNE RTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLR TILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYL FHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQGLIIDAFGELR DQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMYLINKDETEHT GQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS

Structure information

PDB ID	8duj (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Global map in C1 of RyR1 particles in complex with ImperaCalcin
Assembly ID	1
Resolution	3.7Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	157
Sequence identity between the two chains	0.987
PubMed citation	37224245

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	A	G
UniProt accession	P11716	P11716
Species	9986 (Oryctolagus cuniculus)	9986 (Oryctolagus cuniculus)
Function annotation	BioLiP:8dujA	BioLiP:8dujG

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 8duj-a1-m1-cA_8duj-a1-m1-cG.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 8duj-assembly1.cif.gz