8dve/1/1:J/1:G

Sequences

>8dve-a1-m1-cJ (length=3943) [Search sequence]

VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLE QSLSVRALQEMLANGHRTLLYGHAILLRHAHSRMYLSCLTTSRKLAFDVGLQEDATGEAC WWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPIC SCCEEGYVTGGHVLRLFHGECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISW SGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEEGMGPPEI KYGESLCFVQHVASGLWLTYAALKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAG LYNQFIKGLDSFSGKPRPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQS LFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRAN CALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRN HKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGS TQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGF DGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGL FFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRG PHLVGPSRCLSHTDFVPIVLPPHLERIREKLAENIHELWALTRILPEPERNYNLQMSGET LKTLLALPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEAT KRSNRDSLCQAVRTLLGYGYNIEPDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWA RPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLN GEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEP FAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVE MLFLRLSLPVQFHQHFRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNF DLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVHTDLVIGCLVDLATGLMTFTANG KESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPP RLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILEL SERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYD LLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPRHGLPGVGVTTSLRPPHHFSPPC FVAALPAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVST LLVMGIFGDEDVKQILKMIEPEVFTEEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVE SLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDDC PLPEDIRQDLQDFHQDLLAHCGIQLPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLH RQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNI MNNKVFYQHPNLMRALGMHETVMEVMVNVLGEIRFPKMVTSCCRFLCYFCRISRQNQRSM FDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSC PMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRG EGGSGLLAAIEEAIRISEDPARDNRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEA LRIRAILRSLVPLDDLVGIISLPLQIPVQPKMSASFVPDHKASMVLFLDRVYGIENQDFL LHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIM VDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAK MPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRM AMPCLCAIAPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFS EKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEERTEKKKTRKISQTAQTYDPREGYNPQ PPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKAR DREKAQELLKFLQMNGYAVTRIEKRFAFGFLQQLLRWMDISQEFIAHLEAHEQEIKFFAK ILLPLINQYFTNHCLYFLSNKEKEMITSLFCKLAALVRHVVNCLHILARKAGLRSFFESA SEDIEKMVENLRQNLTYTTVALLPVLTTLFQHIAQHDVQVSCYRTLCSIYSLRPALGECL ARLAARLMADIGGLAPHVIEITLPMLCSYLPRWSDHLNSLLGNILRIIVNNRLAVFAQPI VSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRDEFSVLCRDLYALYPLLIRYVDNNR AHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEIVATLKKMLPIGLNMCD QDLIMLAKTRYALKDTDEEVREFLQNDPEKIVRRVQEVSAVLYHLEQTEHSKQRRRAVVA CFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGKKPDPLHQLVLHF SRTALTEKSKLDEDYLYMAYADIMAKSCHLEEVSFEEKEMEKQRLLYQQSRLHTRGAAEM VLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQT CSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNND FQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVA KQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLD LQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQ DYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARD IGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEIS ETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISETAREA ATALAALLWAVVARWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSP PNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFD GLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMD LASLEITAHNETWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHLL DIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPDM KCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQG LIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLMY LINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS

>8dve-a1-m1-cG (length=3944) [Search sequence]

VQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPDLAICCFTLE QSLSVRALQEMLANGHRTLLYGHAILLRHAHSRMYLSCLTTSRKLAFDVGLQEDATGEAC WWTMHPASKQRSEGEKVRVGDDLILVSVSSERYLHLSTASGELQVDASFMQTLWNMNPIC SCCEEGYVTGGHVLRLFHGECLTISAADSDDQRRLVYYEGGAVCTHARSLWRLEPLRISW SGSHLRWGQPLRIRHVTTGRYLALTEDQGLVVVDACKAHTKATSFCFRVSKEEGMGPPEI KYGESLCFVQHVASGLWLTYAALKKKAILHQEGHMDDALFLTRCQQEESQAARMIHSTAG LYNQFIKGLDSFSGKPRPALPIEAVILSLQDLIGYFEPPSEELQHEEKQSKLRSLRNRQS LFQEEGMLSLVLNCIDRLNVYTTAAHFAEYAGEEAAESWKEIVNLLYELLASLIRGNRAN CALFSTNLDWVVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRN HKVLDVLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGS TQYGKWYFEVMVDEVVPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGF DGLHLWTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFEAFNLDGL FFPVVSFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLRLEPIKEYRREGPRG PHLVGPSRCLSHTDFVPIVLPPHLERIREKLAENIHELWALTRILPEPERNYNLQMSGET LKTLLALPAQTTLVDRLAENGHNVWARDRVAQGWSYSAVQDIPARRNPRLVPYRLLDEAT KRSNRDSLCQAVRTLLGYGYNIEPDRVRIFRAEKSYTVQSGRWYFEFEAVTTGEMRVGWA RPELRPDVELGADELAYVFNGHRGQRWHLGSEPFGRPWQSGDVVGCMIDLTENTIIFTLN GEVLMSDSGSETAFREIEIGDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEP FAINMQRPVTTWFSKSLPQFEPVPPEHPHYEVARMDGTVDTPPCLRLAHRTWGSQNSLVE MLFLRLSLPVQFHQHFRDDPEIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMNF DLSKVRAVTVTMGDEQGNVHSSLKCSNCYMVWGGDFVHTDLVIGCLVDLATGLMTFTANG KESNTFFQVEPNTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFLSERKNPAPQCPP RLEVQMLMPVSWSRMPNHFLQVETRRAGERLGWAVQCQDPLTMMALHIPEENRCMDILEL SERLDLQRFHSHTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYD LLISIHLESACRSRRSMLSEYIVPLTPETRAITLFPPRHGLPGVGVTTSLRPPHHFSPPC FVAALPAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLKLVST LLVMGIFGDEDVKQILKMIEPEVFTEEEGLLQMKLPESVKLQMCNLLEYFCDQELQHRVE SLAAFAERYVDKLQANQRSRYALLMRAFTMSAAETARRTREFRSPPQEQINMLLHFKDDC PLPEDIRQDLQDFHQDLLAHCGIQLPQSLQELVSHMVVRWAQEDYVQSPELVRAMFSLLH RQYDGLGELLRALPRAYTISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQSIGNI MNNKVFYQHPNLMRALGMHETVMEVMVNVLGEIRFPKMVTSCCRFLCYFCRISRQNQRSM FDHLSYLLENSGIGLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSC PMLLAKGYPDIGWNPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRG EGGSGLLAAIEEAIRISEDPARDNRVHLGHAIMSFYAALIDLLGRCAPEMHLIQAGKGEA LRIRAILRSLVPLDDLVGIISLPLQIPVQPKMSASFVPDHKASMVLFLDRVYGIENQDFL LHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLITKCAPLFAGTEHRAIM VDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLLRRLVFDVPILNEFAK MPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIFDSLAHKKYDQELYRM AMPCLCAIAPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENVDEELKTHPMLRPYKTFS EKDKEIYRWPIKESLKAMIAWEWTIEKAREGEEERTEKKKTRKISQTAQTYDPREGYNPQ PPDLSGVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKAR DREKAQELLKFLQMNGYAVTRIEKRFAFGFLQQLLRWMDISQEFIAHLEAHEQEIKFFAK ILLPLINQYFTNHCLYFLSNKEKEMITSLFCKLAALVRHVVNCLHILARKAGLRSFFESA SEDIEKMVENLRQNLTYTTVALLPVLTTLFQHIAQHDVQVSCYRTLCSIYSLRPALGECL ARLAARLMADIGGLAPHVIEITLPMLCSYLPRWSDHLNSLLGNILRIIVNNRLAVFAQPI VSRARPELLHSHFIPTIGRLRKRAGKVVAEEEQLRDEFSVLCRDLYALYPLLIRYVDNNR AHWLTEPNANAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNEIVATLKKMLPIGLNMCD QDLIMLAKTRYALKDTDEEVREFLQNDPEKIVRRVQEVSAVLYHLEQTEHSKQRRRAVVA CFRMTPLYNLPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGKKPDPLHQLVLHF SRTALTEKSKLDEDYLYMAYADIMAKSCHLEEVSFEEKEMEKQRLLYQQSRLHTRGAAEM VLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKKEVGFFQSIQALMQT CSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDLFRFLQLLCEGHNND FQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIEEQGKRNFSKAMSVA KQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLAQDSSQIELLKELLD LQKDMVVMLLSLLEGNVVNGMIARQMVDMLVESSSNVEMILKFFDMFLKLKDIVGSEAFQ DYVTDPRGLISKKDFQKAMDSQKQFTGPEIQFLLSCSEADENEMINFEEFANRFQEPARD IGFNVAVLLTNLSEHVPHDPRLRNFLELAESILEYFRPYLGRIEIMGASRRIERIYFEIS ETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFEMQIAAQISETAREA ATALAALLWAVVARWGELEVQRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSP PNMVYYFLEESTGYMEPALWCLSLLHTLVAFLCIIGYNCLKVPLVIFKREKELARKLEFD GLYITEQPGDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLDKHGDIFGRERIAELLGMD LASLEITAHNERTWLMSIDVKYQIWKFGVIFTDNSFLYLGWYMVMSLLGHYNNFFFAAHL LDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAVVVYLYTVVAFNFFRKFYNKSEDEDEPD MKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDEYELYRVVFDITFFFFVIVILLAIIQ GLIIDAFGELRDQQEQVKEDMETKCFICGIGSDYFDTTPHGFETHTLEEHNLANYMFFLM YLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLS

Structure information

PDB ID	8dve (database links: RCSB PDB PDBe PDBj PDBsum)
Title	RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands
Assembly ID	1
Resolution	3.84Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	170
Sequence identity between the two chains	1.0
PubMed citation	37224245

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	J	G
UniProt accession	P11716	P11716
Species	9986 (Oryctolagus cuniculus)	9986 (Oryctolagus cuniculus)
Function annotation	BioLiP:8dveJ	BioLiP:8dveG

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 8dve-a1-m1-cJ_8dve-a1-m1-cG.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 8dve-assembly1.cif.gz

Similar dimers

Other dimers with similar sequences and structures

8duj/1/1:J/1:G 8dve/1/1:A/1:G 8dve/1/1:D/1:A 8dve/1/1:D/1:J