8e0q/1/1:A/1:B |
| >8e0q-a1-m1-cA (length=1689) [Search sequence] |
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
LLEDGRVCRIGFSVQPDRLSPVSLGEDLQWWPDKDGTKFICIGALYSELLAVSSKGELYQ
WKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLS
SVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENSLYWWGVVPFSQRKKMLEKARAK
NKPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNEEQWSLREVVFVE
DVTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQE
NNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPI
SSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVVL
EQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKVESKDRKANAHFILKLLCDSVVLQP
YLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEISSSEKEEDVFMGMVCP
SGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHD
CKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLV
QTVARQTVEHCQYRPPRIREDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQEN
KDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQ
NKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPY
AVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSMLDEP
LERTTNSSHANGAAQAPRSMQWAVRNNASSYLTSASSLARAYSIVIRQISDLMGLIPKYN
HLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPG
HPNHPLHASQNSARRMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALI
YWIKAMNQQTTETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARK
EDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPTKMSPPLTSFRPQCSFMGMVISHD
MLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSLE
VDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAF
LSNEKLPNLECIQNDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNEL
CPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAID
LCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKN
SLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTE
RQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQ
KLLLAIKTK |
| >8e0q-a1-m1-cB (length=1689) [Search sequence] |
MTSIHFVVHPLPGTEDQLNDRLREVSEKLNKYNLNSHPPLNVLEQATIKQCVVGPNHAAF
LLEDGRVCRIGFSVQPDRLSPVSLGEDLQWWPDKDGTKFICIGALYSELLAVSSKGELYQ
WKWSESEPYRNAQNPSLHHPRATFLGLTNEKIVLLSANSIRATVATENNKVATWVDETLS
SVASKLEHTAQTYSELQGERIVSLHCCALYTCAQLENSLYWWGVVPFSQRKKMLEKARAK
NKPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNEEQWSLREVVFVE
DVTPKVPDCFQRTPKKLCIPEKTEILAVNVDSKGVHAVLKTGNWVRYCIFDLATGKAEQE
NNFPTSSIAFLGQNERNVAIFTAGQESPIILRDGNGTIYPMAKDCMGGIRDPDWLDLPPI
SSLGMGVHSLINLPANSTIKKKAAVIIMAVEKQTLMQHILRCDYEACRQYLMNLEQAVVL
EQNLQMLQTFISHRCDGNRNILHACVSVCFPTSNKVESKDRKANAHFILKLLCDSVVLQP
YLRELLSAKDARGMTPFMSAVSGRAYPAAITILETAQKIAKAEISSSEKEEDVFMGMVCP
SGTNPDDSPLYVLCCNDTCSFTWTGAEHINQDIFECRTCGLLESLCCCTECARVCHKGHD
CKLKRTSPTAYCDCWEKCKCKTLIAGQKSARLDLLYRLLTATNLVTLPNSRGEHLLLFLV
QTVARQTVEHCQYRPPRIREDSDMPDHDLEPPRFAQLALERVLQDWNALKSMIMFGSQEN
KDPLSASSRIGHLLPEEQVYLNQQSGTIRLDCFTHCLIVKCTADILLLDTLLGTLVKELQ
NKYTPGRREEAIAVTMRFLRSVARVFVILSVEMASSKKKNNFIPQPIGKCKRVFQALLPY
AVEELCNVAESLIVPVRMGIARPTAPFTLASTSIDAMQGSEELFSVEPLPPRPSSMLDEP
LERTTNSSHANGAAQAPRSMQWAVRNNASSYLTSASSLARAYSIVIRQISDLMGLIPKYN
HLVYSQIPAAVKLTYQDAVNLQNYVEEKLIPTWNWMVSIMDSTEAQLRYGSALASAGDPG
HPNHPLHASQNSARRMSARGDFLNYALSLMRSHNDEHSDVLPVLDVCSLKHVAYVFQALI
YWIKAMNQQTTETGQNHPFFRRSDSMTFLGCIPPNPFEVPLAEAIPLADQPHLLQPNARK
EDLFGRPSQGLYSSSASSGKCLMEVTVDRNCLEVLPTKMSPPLTSFRPQCSFMGMVISHD
MLLGRWRLSLELFGRVFMEDVGAEPGSILTELGGFEVKESKFRREMEKLRNQQSRDLSLE
VDRDRDLLIQQTMRQLNNHFGRRCATTPMAVHRVKVTFKDEPGEGSGVARSFYTAIAQAF
LSNEKLPNLECIQNDNAPLFYQPGKRGFYTPRPGKNTEARLNCFRNIGRILGLCLLQNEL
CPITLNRHVIKVLLGRKVNWHDFAFFDPVMYESLRQLILASQSSDADAVFSAMDLAFAID
LCKEEGGGQVELIPNGVNIPVTPQNVYEYVRKYAEHRMLVVAEQPLHAMRKGLLDVLPKN
SLEDLTAEDFRLLVNGCGEVNVQMLISFTSFNDESGENAEKLLQFKRWFWSIVEKMSMTE
RQDLVYFWTSSPSLPASEEGFQPMPSITIRPPDDQHLPTANTCISRLYVPLYSSKQILKQ
KLLLAIKTK |
|
| PDB ID |
8e0q (database links:
RCSB PDB
PDBe
PDBj
PDBsum) |
| Title |
Structure of the human UBR5 HECT-type E3 ubiquitin ligase in a C2 symmetric dimeric form |
| Assembly ID |
1 |
| Resolution |
2.66Å |
| Method of structure determination |
ELECTRON MICROSCOPY |
| Number of inter-chain contacts |
520 |
| Sequence identity between the two chains |
1.0 |
| PubMed citation |
37040767 |
|
|
Chain 1 |
Chain 2 |
| Model ID |
1 |
1 |
| Chain ID |
A |
B |
| UniProt accession |
O95071 |
O95071 |
| Species |
9606 (Homo sapiens) |
9606 (Homo sapiens) |
| Function annotation |
BioLiP:8e0qA |
BioLiP:8e0qB |
|
Switch viewer: [NGL] [JSmol]
|
Dimer structure:
Chain 1 in red;
Chain 2 in blue.
|
Full biological assembly
|
|
| Other dimers with similar sequences and structures |
8d4x/1/1:B/1:A 8ewi/1/1:A/1:B 8ewi/1/1:C/1:D |
| Other dimers with similar sequences but different poses |
8ewi/1/1:B/1:D 8ewi/1/1:A/1:C |
|