8eyr/1/1:B/1:A

Sequences

>8eyr-a1-m1-cB (length=794) [Search sequence]

EICGPGIDIRNDYQQLKRLENCTVIEGFLHILLISKAEDYRSYRFPKLTVITEYLLLFRV AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLC YLSTIDWSLILDAVSNNYIVGNKPPKECGDLCPCEKTTINNEYNYRCWTTNRCQKMCPSV CACTENNECCHPECLGSCHTPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDF CANIPNAESGFVIHDDECMQECPSGFIRNSTQSMYCIPCVCGDEEKKTKTIDSVTSAQML QGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILG EEQLEGNYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTKG RQSKGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEA PFKNVTEYDCGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDHI RGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQD GYLYRHNYCSKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPYPFFESRVDNKERTVISN LRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKW PEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSG NGSWTDPVFFYVPA

>8eyr-a1-m1-cA (length=795) [Search sequence]

EICGPGIDIRNDYQQLKRLENCTVIEGFLHILLISKAEDYRSYRFPKLTVITEYLLLFRV AGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLC YLSTIDWSLILDAVSNNYIVGNKPPKECGDLCPCEKTTINNEYNYRCWTTNRCQKMCPSV CACTENNECCHPECLGSCHTPDDNTTCVACRHYYYKGVCVPACPPGTYRFEGWRCVDRDF CANIPNAESGFVIHDDECMQECPSGFIRNSTQSMYCIPCKVCGDEEKKTKTIDSVTSAQM LQGCTILKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLIL GEEQLEGNYSFYVLDNQNLQQLWDWNHRNLTVRSGKMYFAFNPKLCVSEIYRMEEVTGTK GRQSKGDINTRNNGERASCESDVLRFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKE APFKNVTEYDCGSNSWNMVDVDLPPNKEGEPGILLHGLKPWTQYAVYVKAVTLTMVENDH IRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPTLPNGNLSYYIVRWQRQPQ DGYLYRHNYCSKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPYPFFESRVDNKERTVIS NLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLK WPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLS GNGSWTDPVFFYVPA

Structure information

PDB ID	8eyr (database links: RCSB PDB PDBe PDBj PDBsum)
Title	Cryo-EM structure of two IGF1 bound full-length mouse IGF1R mutant (four glycine residues inserted in the alpha-CT; IGF1R-P674G4): symmetric conformation
Assembly ID	1
Resolution	4.0Å
Method of structure determination	ELECTRON MICROSCOPY
Number of inter-chain contacts	68
Sequence identity between the two chains	1.0

Chain information

	Chain 1	Chain 2
Model ID	1	1
Chain ID	B	A
UniProt accession	Q60751	Q60751
Species	10090 (Mus musculus)	10090 (Mus musculus)

3D structure

Dimer structure: Chain 1 in red; Chain 2 in blue. Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black]   [White]   Download: 8eyr-a1-m1-cB_8eyr-a1-m1-cA.pdb.gz

Full biological assembly Color: [By chain]   [By residue index]   Spin: [Spin off]   [Spin on]   [Reset] Render: [Low quality]   [High quality]   Background: [Black quality]   [White quality]   Download: 8eyr-assembly1.cif.gz