8fwq/1/1:C/1:D

Sequences
>8fwq-a1-m1-cC (length=818) [Search sequence]
THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEAS
KKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPD
FSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAK
PLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYS
GVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSV
AVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVI
SLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKP
LYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADL
AVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACL
GVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALS
TRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMT
FFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNL
TQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEA
SALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA
>8fwq-a1-m1-cD (length=818) [Search sequence]
THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEAS
KKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPD
FSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAK
PLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYS
GVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSV
AVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVI
SLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKP
LYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDVNGQWNGMVRELIDHKADL
AVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACL
GVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALS
TRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMT
FFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNL
TQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEA
SALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNA
Structure information
PDB ID 8fwq (database links: RCSB PDB PDBe PDBj PDBsum)
Title Structure of kainate receptor GluK2 in complex with the positive allosteric modulator BPAM344
Assembly ID 1
Resolution 3.96Å
Method of structure determination ELECTRON MICROSCOPY
Number of inter-chain contacts 269
Sequence identity between the two chains 1.0
PubMed citation 36857176
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID C D
UniProt accession P42260 P42260
Species 10116 (Rattus norvegicus) 10116 (Rattus norvegicus)
Function annotation BioLiP:8fwqC BioLiP:8fwqD
3D structure
Switch viewer: [NGL] [JSmol]
Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 8fwq-a1-m1-cC_8fwq-a1-m1-cD.pdb.gz
Full biological assembly
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Download: 8fwq-assembly1.cif.gz
Similar dimers
Other dimers with similar sequences and structures 7f57/1/1:A/1:B 7f57/1/1:D/1:C 8fwq/1/1:A/1:B 8fwr/1/1:A/1:B 8fwr/1/1:C/1:D 8fwt/1/1:A/1:B 8fwt/1/1:C/1:D 8fwv/1/1:A/1:B 8fwv/1/1:C/1:D
Other dimers with similar sequences but different poses
  • 7f56/1/1:A/1:B 3h6g/1/1:A/1:B 3h6h/1/1:B/1:A 3qlt/1/1:B/1:A
  • 8fwq/1/1:B/1:D 3qlv/1/1:C/1:D 3qlv/2/1:F/1:H 3qlv/3/1:J/2:J 7ks0/1/1:B/1:D 8fwr/1/1:B/1:D 8fwt/1/1:B/1:D 8fwv/1/1:B/1:D
  • 7f57/1/1:D/1:A 7f56/1/1:D/1:A 7f57/1/1:B/1:C
  • 8fws/1/1:A/1:C 7f57/1/1:D/1:B
  • 7f5b/1/1:B/1:A 7f59/1/1:B/1:A
  • 7f5b/1/1:D/1:A 7f59/1/1:B/1:C 7f5a/1/1:D/1:A 7f5b/1/1:B/1:C
  • 7f5a/1/1:B/1:C 7f59/1/1:D/1:A
  • 7f5a/1/1:B/1:D 7f59/1/1:D/1:B
  • 7f5b/1/1:D/1:C 7f59/1/1:D/1:C
  • 8fws/1/1:C/1:D 7f5a/1/1:B/1:A 8fws/1/1:A/1:B 8fwu/1/1:A/1:B 8fwu/1/1:C/1:D 8fww/1/1:A/1:B 8fww/1/1:C/1:D
  • 8fws/1/1:A/1:D 8fwq/1/1:A/1:D 8fwq/1/1:B/1:C 8fws/1/1:B/1:C 8fwu/1/1:A/1:D 8fwu/1/1:B/1:C 8fww/1/1:A/1:D 8fww/1/1:B/1:C
    		•

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