8grb/2/1:F/1:H

Sequences
>8grb-a2-m1-cF (length=315) [Search sequence]
SFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLKLEQVLSSMKENKVAIIGKIAS
YDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECLK
IVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFET
MIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETGA
RHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGYA
TCHDFTEEICRRVKD
>8grb-a2-m1-cH (length=319) [Search sequence]
SFPVTMLPGDGVGPELMHAVKEVFKAAAVPVEFQEHHLSKLEQVLSSMKENKVAIIGKIA
SYDMRLRRKLDLFANVVHVKSLPGYMTRHNNLDLVIIREQTEGEYSSLEHESARGVIECL
KIVTRAKSQRIAKFAFDYATKKGRGKVTAVHKANIMKLGDGLFLQCCEEVAELYPKIKFE
TMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAAGLVGGAGVVPGESYSAEYAVFETG
ARHPFAQAVGRNIANPTAMLLSASNMLRHLNLEYHSSMIADAVKKVIKVGKVRTSDMGGY
ATCHDFTEEICRRVKDLDE
Structure information
PDB ID 8grb (database links: RCSB PDB PDBe PDBj PDBsum)
Title Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3
Assembly ID 2
Resolution 2.848Å
Method of structure determination X-RAY DIFFRACTION
Number of inter-chain contacts 12
Sequence identity between the two chains 1.0
Chain information
Chain 1 Chain 2
Model ID 1 1
Chain ID F H
UniProt accession O43837-2 O43837-2
Species 9606 (Homo sapiens) 9606 (Homo sapiens)
3D structure
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Dimer structure: Chain 1 in red; Chain 2 in blue.
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Download: 8grb-a2-m1-cF_8grb-a2-m1-cH.pdb.gz
Full biological assembly
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Download: 8grb-assembly2.cif.gz
Similar dimers
Other dimers with similar sequences and structures 8grb/1/1:C/1:D 8grb/3/1:J/1:L 8grb/4/1:N/1:P

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