" >

IonCom is a ligand-specific method for small ligand (including metal and acid radical ions) binding site prediction. Starting from given sequences or structures of the query proteins, IonCom performs a composite binding-site prediction that combines ab initio training and template-based transferals. To enhance specificity and sensitivity, the server focuses on binding site prediction of thirteen most important small ligand molecules, including nine metal ions (Zn²⁺, Cu²⁺, Fe²⁺, Fe³⁺, Ca²⁺, Mg²⁺, Mn²⁺, Na⁺, K⁺) and four acid radical ions (CO₃^2-, NO₂^-, SO₄^2-, PO₄^3-).

[View an example of output] [Download standalone IonCom program ] [Download dataset used to train/test IonCom ]