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# LOMETS results for example

#### [Click result.zip to download all results on this page]

Input Sequence in FASTA format

>protein (123 residues) FVAELNNLLGREVQVVLSNGEVYKGVLHAVDNQLNIVLANASNKAGEKFNRVFIYRYIVH IDSTERRIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFE EFL

Predicted Secondary Structure

Sequence

20 40 60 80 100 120
| | | | | |
FVAELNNLLGREVQVVLSNGEVYKGVLHAVDNQLNIVLANASNKAGEKFNRVFIYRYIVHIDSTERRIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
Prediction
CHHHHHHHCCCSSSSSSCCCCSSSSSSSSCCCCSSSSSSSSSSCCCCSSSSSSSSCSSSSSSCCCCCCHHHHHHHHHHHCCCCSSSCCCCSSSSSSSSSSSCCCCCCCCHHHHHHHHHHHHHC
Conf.Score 868989875989999997997999999976987489998767578987889999677999987887674999999999779978985688899975799865775577789999999999769
H:Helix; S:Strand; C:Coil
Predicted Solvent Accessibility

Sequence | 20 40 60 80 100 120 | | | | | | FVAELNNLLGREVQVVLSNGEVYKGVLHAVDNQLNIVLANASNKAGEKFNRVFIYRYIVHIDSTERRIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
Prediction | 645404521444030303645404020343444010203304566654111010332134053365621540053046216504316524003024414034531524231053035106626
| Values range from 0 (buried residue) to 8 (highly exposed residue)

Predicted Contact and Distance Map Used in LOMETS

Contact Map | Distance Map

LOMETS threading is guided by the consensus contact map (left figure) and distance map (right figure) derived based on confidence scores of DeepPotential. In the contact and distance maps, the axes mark the residue index along the sequence. For the contact map, each dot represents a residue pair with predicted contact, while for the distance map a color scale represents a distance of 1-20+ angstroms. No dot is close to the diagonal in the contact map, because LOMETS does not consider contacts for residue pairs separated by <4 residues.

Predicted Domain Information by FUpred

Contact Map | Scoring Map

LOMETS uses FUpred and ThreaDom to predict the domain boundary for the target protein. Where ThreaDom is used for homologous target and FUpred is used for non-homologous target. The domain prediction result is shown in the predicted contact map (left) and the FUscore for continuous/discontinuous domain are also shown (right).

Domain partition by LOMETS and Individual Domain Threading/Modeling Results

No. of Domain | Domain | Domain Boundary | Length of Domain | Models of Domain | Sequence
1 | example-D1 | 1-66 | 66 |  | FVAELNNLLGREVQVVLSNGEVYKGVLHAVDNQLNIVLANASNKAGEKFNRVFIYRYIVHIDSTER
2 | example-D2 | 67-123 | 57 |  | RIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
Modeling the target as 2 domain protein. Click the Domain column or image, you can go into the individual page to check the individual domain threading/modeling results.

Top 10 Assembled Templates by LOMETS

Rank | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | DownloadAlignment |  | 20 40 60 80 100 120 | | | | | |
| Sec.Str. Sol.Acc. Seq | CHHHHHHHCCCSSSSSSCCCCSSSSSSSSCCCCSSSSSSSSSSCCCCSSSSSSSSCSSSSSSCCCCCCHHHHHHHHHHHCCCCSSSCCCCSSSSSSSSSSSCCCCCCCCHHHHHHHHHHHHHC 645404521444030303645404020343444010203304566654111010332134053365621540053046216504316524003024414034531524231053035106626 FVAELNNLLGREVQVVLSNGEVYKGVLHAVDNQLNIVLANASNKAGEKFNRVFIYRYIVHIDSTERRIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
1 | 0.608 | 1.664 | 0.20 | 0.20 | 0.98 | 1.60 | LOMETS-Assemble |  | LGATLQDSIGKQVLVKLRDSHEIRGILRSFDQHVNLLLEDAEEINVYKRGTMVVRENVLFISPVP-SIVEQFVQTLE KGFSDIKVEDTGHIV LLQEETLIQITHIICDNMLRVRLRDLVLK--
2 | 0.586 | 1.885 | 0.21 | 0.20 | 0.95 | 1.60 | LOMETS-Assemble |  | LGATLQDSIGKQVLVKLRDSHEIRGILRSFDQHVNLLLEDAEEINVYKRGTMVVRENVLFISPVP-AIVNKVAEMARERGYTVDT---TDGAKIIFWVLVRAIRIFSEAEYLNLGIELLEK--
3 | 0.599 | 1.715 | 0.19 | 0.19 | 0.98 | 1.60 | LOMETS-Assemble |  | LGATLQDSIGKQVLVKLRDSHEIRGILRSFDQHVNLLLEDAEEINVYKRGTMVVRENVLFISPVP-SIPVEQFVQTLEKHSDIKVETAGHIV LLQEATLIQDSTIICDNDLRVRLRDLVLKF-
4 | 0.571 | 1.847 | 0.16 | 0.15 | 0.94 | 1.60 | LOMETS-Assemble |  | LGATLQDSIGKQVLVKLRDSHEIRGILRSFDQHVNLLLEDAEEIIDYKRGTMVVRENVLFISPVP-TA-LRVYSHLKSVH-CVQHLP-DGSVTVE-SVLLQAALVSWTEELGSLTSLLKKG--
5 | 0.552 | 1.876 | 0.18 | 0.18 | 0.98 | 1.60 | LOMETS-Assemble |  | LGATLQDSIGKQVLVKLRDSHEIRGILRSFDQHVNLLLEDAEEIIDYKRGTMVVRENVLFISPVP-IPVEQFVQTLE KHGFSDIVEDTGHIV LLQEAETLIQSTCDNDEMLRVRLRDLVLKF-
6 | 0.574 | 1.750 | 0.20 | 0.20 | 0.98 | 1.60 | LOMETS-Assemble |  | GTTKMVSL LNHSLNVTTKDGRTFVGQLLAFDGFMNLV LSDCQEYEKRMLGLVILRGFI VSLSVQG-IPVEQFVQTLE KHFSDIKVEDKGHIV LLQEATLIQIEICDNDEMLRVRLRDLVLKF-
7 | 0.562 | 1.868 | 0.14 | 0.14 | 0.98 | 1.60 | LOMETS-Assemble |  | GTTKMVSL LNHSLNVTTKDGRTFVGQLLAFDGFMNLV LSDCQEYEKRMLGLVILRGFI VSLSVQG-ETALRVYSHLKSVLDHCVQHLPDGSVTVESVLLQAAALVSWDEELGSFLTSLLKGL-
8 | 0.577 | 1.917 | 0.15 | 0.15 | 0.98 | 1.20 | LOMETS-Assemble |  | PLALIDKCIGNRIYV VMKGDKEFSG V LRGFDEYVNMV LDDVQEYMVNRLETILLSNNVAMLVPGG-NIETESRQFIENKNYSIQSIGPMLRVVFTRLATVDQYLTGANRSLGQELADHLFET-
9 | 0.577 | 1.917 | 0.15 | 0.15 | 0.98 | 1.20 | LOMETS-Assemble |  | PLALIDKCIGNRIYV VMKGDKEFSG V LRGFDEYVNMV LDDVQEYMVNRLETILLSNNVAMLVPGG-NIETESRQFIENKNYSIQSIGPMLRVVFTRLATVDQYLTGANRSLGQELADHLFET-
10 | 0.534 | 1.829 | 0.18 | 0.18 | 0.98 | 1.20 | LOMETS-Assemble |  | PLALIDKCIGNRIYV VMKGDKEFSG V LRGFDEYVNMV LDDVQEYMVNRLETILLSNNVAMLVPGG-IPVEQFVQTLE KHFSDIKVEDTGHIV LLQELIQIEEDSCDNDEMLRVRLRDLVLKF-
(a) | Templates are ranked in descending order of the following score: score(i,j)=conf(i)·Z(i,j)/Z0(i)+seqid(i,j), where Z(i,j) is the Z-score of j-th template; Z0(i) is the Z-score cutoff for defining good/bad templates for the i-th server; conf(i) is the confidence which is defined as the average TM-score to the natives of all predictions calculated from a large-scale benchmark test; and seqid(i,j) is the sequence identity to query of j-th template. (See here for details)
(b) | CMO is the contact map overlap score, calculated from the number of overlapping contacts between the predicted contact map and the contact map derived from the aligned template, then normalized by the number of predicted contacts.
(c) | MAE is the mean absolute error between the predicted distance map and the distance map derived from the aligned template.
(d) | ID1 is the number of template residues identical to query divided by the number of aligned residues.
(e) | ID2 is the number of template residues identical to query divided by the query sequence length.
(f) | Cov is equal to the number of aligned template residues divided by the query sequence length.
(g) | Norm. Zscore is the normalized Z-score of the threading alignments. A normalized Z-score ≥1 means a good alignment.
(h) | Download Alignment list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.
(i) | Sec.Str. is predicted secondary structure, with H, S and C representing helix, strand, and coil, respectively.
(j) | Sol.Acc. is predicted solvent accessibility, where values range from 0 (buried residue) to 8 (highly exposed residue)

Top 10 Full-chain Threading Templates Identified by LOMETS

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | DownloadAlignment |  | 20 40 60 80 100 120 | | | | | |
| Sec.Str. Sol.Acc. Seq | CHHHHHHHCCCSSSSSSCCCCSSSSSSSSCCCCSSSSSSSSSSCCCCSSSSSSSSCSSSSSSCCCCCCHHHHHHHHHHHCCCCSSSCCCCSSSSSSSSSSSCCCCCCCCHHHHHHHHHHHHHC 645404521444030303645404020343444010203304566654111010332134053365621540053046216504316524003024414034531524231053035106626 FVAELNNLLGREVQVVLSNGEVYKGVLHAVDNQLNIVLANASNKAGEKFNRVFIYRYIVHIDSTERRIDREFAKQAEKIFPGVKYIEETNVVLIGDKVRVSEIGVEGVGPVAERAKRLFEEFL
1 | 5mkl11 | 5mkl | 0.349 | 3.250 | 0.24 | 0.21 | 0.87 | 1.24 | HHpred |  | PLKSLKTALNKIVLVKLKN G EEYVGRLEQSDGTMNLV LKDCTEDPVAKYGR VLIRSNILFISIDYESIMENPLKSLKTALNKVLVKSDGTMNLVLKDCTEYREGTDP----------------
2 | 6ppnB | 6ppn | 0.435 | 1.947 | 0.25 | 0.17 | 0.68 | 1.60 | SparksX |  | FYSFFKTLIDTE VTVELKNDMSIRGILKSV DQFL NVKLENISVVDAAAVKDLF IRSVVRYVHMSSAYVDILLADACRRDLANNK---------------------------------------
3 | 3jcr2 | 3jcr | 0.386 | 2.244 | 0.28 | 0.18 | 0.65 | 1.32 | HHsearch |  | FYSFFKSLVGKDVVVELKNDLSICGTL HSV DQYL N IKLTDISVTHMLSVKNCF IRSVVRYVQLPADEVDQLLQDAARKEA-------------------------------------------
4 | 5nrll | 5nrl | 0.454 | 2.064 | 0.18 | 0.14 | 0.76 | 1.31 | MUSTER |  | LVNFLKKLRNEQVTIELKN GTTVWGTLQSVSPQMNAILTDVKLTLIASLQYINIRNTIRQIILPDSLNLDSLLVDQKQLNSLRRSANKRP-----------RRGL------------------
5 | 6ppnB | 6ppn | 0.444 | 2.199 | 0.26 | 0.16 | 0.63 | 1.12 | FFAS3D |  | -YSFFKTLIDTE VTVELKNDMSIRGILKSV DQFL NVKLENISVVDASKVKDLF IRGVVRYVHMSSAYVDTILLADACRR--------------------------------------------
6 | 6v4xC | 6v4x | 0.426 | 2.196 | 0.23 | 0.15 | 0.66 | 1.22 | HHpred |  | LIILLQGLQG RVTTVDLRDESVAHGRIDNV DAFMN IRL AKVTYGHQVKLDDLFVTRNVRYVHIPDD-VNSTIEQQLQIIHRV-----------------------------------------
7 | 5mkl11 | 5mkl | 0.522 | 2.415 | 0.21 | 0.21 | 1.00 | 1.56 | SparksX |  | PLKSLKTALNKIVLVKLKN G EEYVGRLEQSDGTMNLV LKDCTEYREGKYGR VLIRSNILFISIDYESIIENPLKSLKTALNKVLVKLKNGEEYVGRLEQSDGTMNLVLKDCTEYREGTSDPVA
8 | 6ppnD | 6ppn | 0.448 | 2.107 | 0.22 | 0.14 | 0.64 | 1.29 | HHsearch |  | PLTLL NATQG RPILVELKN G ETFNGHLENCD NYMNLTLREVIRTKFFRLPECYIRNNIKYLRIQDEVLSVAKQQAQQRE--------------------------------------------
9 | 4m77A | 4m77 | 0.398 | 2.325 | 0.20 | 0.13 | 0.65 | 1.18 | MUSTER |  | ---TLKDYLNKRVVIILVDG ESLIASLNGFDKNTNLFLTNVFNRISFISKAQLLRSEIALVGLIDAENDDSLIENEHVIWEKV----------------------------------------
10 | 4c8qB | 4c8q | 0.383 | 2.427 | 0.28 | 0.18 | 0.63 | 1.09 | FFAS3D |  | -FSFFKTLVDQE VVVELKNDIEIK GTLQSV DQFL NLKLDNISCTDEKKVRNIF IRGSTVRYVYLNKNVDTNLLQDATRR--------------------------------------------
(a) | Templates are ranked in descending order of the following score: score(i,j)=conf(i)·Z(i,j)/Z0(i)+seqid(i,j), where Z(i,j) is the Z-score of j-th template of i-th server; Z0(i) is the Z-score cutoff for defining good/bad templates for the i-th server; conf(i) is the confidence of i-th server which is defined as the average TM-score to the natives of all predictions calculated from a large-scale benchmark test; and seqid(i,j) is the sequence identity to query of j-th template of i-th server. (See here for details)
(b) | PDB Hit is the PDB of the specific domain/chain aligned to the query.
(c) | RCSB Link is the RCSB PDB link of the full-length protein.
(d) | CMO is the contact map overlap score, calculated from the number of overlapping contacts between the predicted contact map and the contact map derived from the aligned template, then normalized by the number of predicted contacts.
(e) | MAE is the mean absolute error between the predicted distance map and the distance map derived from the aligned template.
(f) | ID1 is the number of template residues identical to query divided by the number of aligned residues.
(g) | ID2 is the number of template residues identical to query divided by the query sequence length.
(h) | Cov is equal to the number of aligned template residues divided by the query sequence length.
(i) | Norm. Zscore is the normalized Z-score of the threading alignments. A normalized Z-score ≥1 means a good alignment.
(j) | Download Alignment list the threading program used to identify the template provide the 3D structure of aligned regions of threading templates.
(k) | Sec.Str. is predicted secondary structure, with H, S and C representing helix, strand, and coil, respectively.
(l) | Sol.Acc. is predicted solvent accessibility, where values range from 0 (buried residue) to 8 (highly exposed residue)
(m) | Images of the top 10 PDB hits are listed below, together with the threading programs used to detect them:
5mkl HHpred,SparksX | 6ppn SparksX,FFAS3D | 3jcr HHsearch | 5nrl MUSTER | 6v4x HHpred | 6ppn HHsearch | 4m77 MUSTER | 4c8q FFAS3D

Full-Length Models

LOMETS uses L-BFGS to construct full-length models guided by the distance restraints predicted by DeepPotential and calculated from top detected templates.
By dragging your mouse on the images, you can rotate and zoom the structure.

Download PDB format Model 1 Download ModelCIF format Model 1 | Download PDB format Model 2 Download ModelCIF format Model 2 | Download PDB format Model 3 Download ModelCIF format Model 3 | Download PDB format Model 4 Download ModelCIF format Model 4 | Download PDB format Model 5 Download ModelCIF format Model 5

Proteins with similar structure

LOMETS uses the TM-align structural alignment program to match the first model to all structures in the PDB library.
This section reports the top 10 proteins from the PDB that have the closest structural similarity, i.e., the highest TM-score, to the predicted model.
Due to the structural similarity, these proteins often have similar functions to the target.

| Top 10 structural analogues in PDB (as identified by TM-align)
Click to view | Rank | RCSB Link | TM-score | RMSDa | IDENa | Cov. | Download PDB | Download FASTA
--- | --- | --- | --- | --- | --- | --- | --- | ---
| 1 | 1m5q | 0.627 | 3.64 | 0.779 | 0.91 | 1m5qY | 1m5qY
| 2 | 4c8q | 0.511 | 2.46 | 0.297 | 0.60 | 4c8qD | 4c8qD
| 3 | 1it7 | 0.511 | 4.36 | 0.069 | 0.82 | 1it7A | 1it7A
| 4 | 4ci7 | 0.51 | 4.27 | 0.08 | 0.81 | 4ci7A | 4ci7A
| 5 | 1i8f | 0.505 | 1.05 | 0.212 | 0.53 | 1i8fF | 1i8fF
| 6 | 3jcr | 0.503 | 1.14 | 0.197 | 0.53 | 3jcr7 | 3jcr7
| 7 | 6ppn | 0.502 | 1.96 | 0.176 | 0.55 | 6ppnH | 6ppnH
| 8 | 3cw1 | 0.5 | 1.72 | 0.314 | 0.56 | 3cw12 | 3cw12
| 9 | 3jcr | 0.499 | 2.01 | 0.246 | 0.56 | 3jcr4 | 3jcr4
| 10 | 6pzk | 0.498 | 4.16 | 0.049 | 0.83 | 6pzkA | 6pzkA

(a) | Query structure is shown in cartoon, while the structural analog is displayed using backbone trace.
(b) | Ranking of proteins is based on TM-score of the structural alignment between the query structure and known structures in the PDB library.
(c) | RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d) | IDENa is the percentage sequence identity in the structurally aligned region.
(e) | Cov. represents the coverage of the alignment by TM-align and is equal to the number of structurally aligned residues divided by the length of the query protein.
(f) | Download PDB provides the structure of the aligned model and template.
(g) | Download FASTA provides the fasta format and full-length alignment of model and template. Shows alignment for potential ligand binding pockets and GO/EC terms.

Function Annotation for Proteins with Similar Structure

(a) | PDB Hit is the PDB of the specific domain/chain aligned to Model 1
(b) | RCSB Link is the RCSB PDB link of the full-length protein.
(c) | Gene Ontology (GO) term and Enzyme Commission (EC) number list the function annotations for structurally aligned proteins, as collected by BioLiP database.
(d) | Ligand lists known binding ligands for each aligned protein, as collected by BioLiP database.
| (e) | Binding Site Residues lists the known binding residues for each ligand as collected by BioLiP database. The residue numbering is based on the specfic domain/chain numbering and highlighted residues means they are present in the alignment with Model 1. Note: Listed binding residues may not be representative of the full ligand binding pocket and may be part of a complex with another protein chain/domain. Also, for a single ligand, one template may have multiple binding sites.

Rank | PDB Hit | RCSB Link | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 1m5qY | 1m5q |  | GO:0000398 | GO:0005732 |  |  |
2 | 4c8qD | 4c8q |  | GO:0006396,GO:0000398,GO:0000956 |  |  |  |
3 | 1it7A | 1it7 | GO:0003723,GO:0016763,GO:0016757,GO:0046872,GO:0016740 | GO:0006400,GO:0008033 |  | 2.4.2.48 | ZN MG GUN | C274 C276 C279 H302 A523 V526 M561 I562 F564 Q565 D90 S93 F94 D125 P127 Q164 G190 G191 V193 F224
4 | 4ci7A | 4ci7 | GO:0008234 | GO:0006508 |  | 3.4.22.15 | CA | L298 E407 K419 N446
5 | 1i8fF | 1i8f |  |  |  |  |  |
6 | 3jcr7 | 3jcr | GO:0003723,GO:0005515,GO:0017070 | GO:0000398,GO:0000956,GO:0006397,GO:0008380,GO:0043928 | GO:0071004,GO:0005689,GO:0071013,GO:0005688,GO:1990726,GO:0005634,GO:0005681,GO:0046540,GO:0071005,GO:0120115,GO:0005654,GO:0005829 |  |  |
7 | 6ppnH | 6ppn |  |  |  |  | NUC | H30 T31 T32 N33 R61 G62 E63
8 | 3cw12 | 3cw1 | GO:0003723,GO:0005515 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0006369,GO:0008334,GO:0051170 | GO:0005732,GO:0005681,GO:0005685,GO:0071013,GO:0005634,GO:0005737,GO:0005829,GO:0005683,GO:0005687,GO:0005689,GO:0030532,GO:0034709,GO:0034715,GO:0034719,GO:0046540,GO:0071005,GO:0071007,GO:0005654 |  |  |
9 | 3jcr4 | 3jcr | GO:0003723,GO:0017070,GO:0005515,GO:0042731 | GO:0006396,GO:0000398,GO:0000956,GO:0000387,GO:0033962,GO:0006397,GO:0008380,GO:0043928 | GO:0000932,GO:0005688,GO:0005634,GO:0005681,GO:0043005,GO:0005829,GO:0016020,GO:0032991,GO:0046540,GO:0071005,GO:0120115,GO:0005654 |  |  |
10 | 6pzkA | 6pzk |  |  |  |  | III | R424 R460 R463

Function Predictions from COFACTOR with LOMETS Structural Analogues and Templates

Protein functions in LOMETS3 are predicted by the modified COFACTOR pipeline, which adds the LOMETS3 threading templates associated with structure analogues as templates in COFACTOR structure-based pipelines. Function predictions include Gene Ontology (GO), Enzyme Commission (EC), and ligand binding sites, where GO is further categorized into three sub-aspects of molecular function (MF), biological process (BP) and cellular component (CC).

Predicted Gene Ontology (GO) Terms

Molecular Function (MF)
GO term | CscoreGO | Name
GO:1901363 | 0.95 | heterocyclic compound binding
GO:0097159 | 0.95 | organic cyclic compound binding
GO:0003676 | 0.94 | nucleic acid binding
GO:0003723 | 0.83 | RNA binding
Download full result of the above consensus prediction.

| Click the graph to show a high resolution version.
(a) | CscoreGO is the confidence score of predicted GO terms. CscoreGO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.
(b) | The graph shows the predicted terms within the Gene Ontology hierachy for Molecular Function. Confidently predicted terms are color coded by CscoreGO:
[0.4,0.5) | [0.5,0.6) | [0.6,0.7) | [0.7,0.8) | [0.8,0.9) | [0.9,1.0]

Biological Process (BP)

GO term | CscoreGO | Name
GO:0009987 | 0.99 | cellular process
GO:0071704 | 0.98 | organic substance metabolic process
GO:0044238 | 0.98 | primary metabolic process
GO:0044237 | 0.97 | cellular metabolic process
GO:0006807 | 0.96 | nitrogen compound metabolic process
GO:0043170 | 0.95 | macromolecule metabolic process
GO:0034641 | 0.95 | cellular nitrogen compound metabolic process
GO:0044260 | 0.94 | cellular macromolecule metabolic process
GO:0006139 | 0.91 | nucleobase-containing compound metabolic process
GO:0016070 | 0.88 | RNA metabolic process
GO:0016071 | 0.77 | mRNA metabolic process
GO:0009058 | 0.72 | biosynthetic process
GO:0044249 | 0.71 | cellular biosynthetic process
GO:0006396 | 0.71 | RNA processing
GO:1901576 | 0.67 | organic substance biosynthetic process
GO:0000377 | 0.67 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
GO:0044271 | 0.65 | cellular nitrogen compound biosynthetic process
GO:0009059 | 0.57 | macromolecule biosynthetic process
GO:0034645 | 0.55 | cellular macromolecule biosynthetic process

Download full result of the above consensus prediction.

| Click the graph to show a high resolution version.
(a) | CscoreGO is the confidence score of predicted GO terms. CscoreGO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.
(b) | The graph shows the predicted terms within the Gene Ontology hierachy for Biological Process. Confidently predicted terms are color coded by CscoreGO:
[0.4,0.5) | [0.5,0.6) | [0.6,0.7) | [0.7,0.8) | [0.8,0.9) | [0.9,1.0]

Cellular Component (CC)

GO term | CscoreGO | Name
GO:0030529 | 1.00 | intracellular ribonucleoprotein complex
GO:0044446 | 0.94 | intracellular organelle part
GO:0097525 | 0.93 | spliceosomal snRNP complex
GO:0044444 | 0.90 | cytoplasmic part
GO:0043229 | 0.90 | intracellular organelle
GO:0097526 | 0.89 | spliceosomal tri-snRNP complex
GO:0005681 | 0.86 | spliceosomal complex
GO:0005634 | 0.76 | nucleus
GO:0071013 | 0.72 | catalytic step 2 spliceosome
GO:0046540 | 0.70 | U4/U6 x U5 tri-snRNP complex
GO:0043234 | 0.69 | protein complex
GO:0043232 | 0.65 | intracellular non-membrane-bounded organelle
GO:0005737 | 0.65 | cytoplasm
GO:0005685 | 0.65 | U1 snRNP
GO:0005687 | 0.63 | U4 snRNP
GO:0071010 | 0.61 | prespliceosome
GO:0005684 | 0.61 | U2-type spliceosomal complex
GO:0005686 | 0.59 | U2 snRNP
GO:0005682 | 0.59 | U5 snRNP
GO:0005829 | 0.56 | cytosol
GO:0071011 | 0.50 | precatalytic spliceosome
GO:0005689 | 0.50 | U12-type spliceosomal complex

Download full result of the above consensus prediction.

| Click the graph to show a high resolution version.
(a) | CscoreGO is the confidence score of predicted GO terms. CscoreGO values range in between [0-1]; where a higher value indicates a better confidence in predicting the function using the template.
(b) | The graph shows the predicted terms within the Gene Ontology hierachy for Cellular Component. Confidently predicted terms are color coded by CscoreGO:
[0.4,0.5) | [0.5,0.6) | [0.6,0.7) | [0.7,0.8) | [0.8,0.9) | [0.9,1.0]

Predicted Enzyme Commission (EC) Numbers

| Top 5 enzyme homologs in PDB
Click to view | Rank | CscoreEC | PDB Hit | TM-score | RMSDa | IDENa | Cov. | EC Number | Predicted Active Site Residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
| 1 | 0.060 | 2gl6A | 0.438 | 3.59 | 0.067 | 0.650 | 2.7.3.2 | NA
| 2 | 0.060 | 1qh3A | 0.444 | 4.35 | 0.085 | 0.780 | 3.1.2.6 | NA
| 3 | 0.060 | 2g8eA | 0.355 | 5.35 | 0.058 | 0.740 | 3.4.22.52 | NA
| 4 | 0.060 | 2c91A | 0.426 | 4.08 | 0.061 | 0.683 | 1.-.-.- | 8,10
| 5 | 0.060 | 3dopB | 0.390 | 4.54 | 0.089 | 0.658 | 1.3.1.3 | 52
| Click on the radio buttons to visualize predicted active site residues.
(a) | CscoreEC is the confidence score for the Enzyme Commission (EC) number prediction. CscoreEC values range in between [0-1]; where a higher score indicates a more reliable EC number prediction.
(b) | TM-score is a measure of global structural similarity between query and template protein.
(c) | RMSDa is the RMSD between residues that are structurally aligned by TM-align.
(d) | IDENa is the percentage sequence identity in the structurally aligned region.
(e) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Predicted Ligand Binding Sites

| Template proteins with similar binding site:
Click to view | Rank | CscoreLB | PDB Hit | TM-score | RMSDa | IDENa | Cov. | BS-score | Lig. Name | Download Complex | Predicted binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
| 1 | 0.09 | 1lnxD | 0.498 | 1.05 | 0.215 | 0.528 | 0.58 | URI | complex1.pdb.gz | 10,13,37
| 2 | 0.03 | 1m8vH | 0.476 | 1.34 | 0.266 | 0.520 | 0.57 | RQA | complex2.pdb.gz | 29,30,31
| 3 | 0.03 | 1lnxG | 0.500 | 1.01 | 0.215 | 0.528 | 0.58 | URI | complex3.pdb.gz | 9,10,13,49,50,51,52
| 4 | 0.01 | 2voyK | 0.125 | 0.86 | 0.048 | 0.130 | 0.58 | III | complex4.pdb.gz | 7,12,13
| Click on the radio buttons to visualize predicted binding site and residues.
(a) | CscoreLB is the confidence score of predicted binding site. CscoreLB values range in between [0-1]; where a higher score indicates a more reliable ligand-binding site prediction.
(b) | BS-score is a measure of local similarity (sequence & structure) between template binding site and predicted binding site in the query structure. Based on large scale benchmarking analysis, we have observed that a BS-score >1 reflects a significant local match between the predicted and template binding site.
(c) | TM-score is a measure of global structural similarity between query and template protein.
(d) | RMSDa the RMSD between residues that are structurally aligned by TM-align.
(e) | IDENa is the percentage sequence identity in the structurally aligned region.
(f) | Cov. represents the coverage of global structural alignment and is equal to the number of structurally aligned residues divided by length of the query protein.

Top Templates and Function Annotation from Component Threading Programs

LOMETS combines templates from multiple individual threading programs, as listed in the following tables.

(a) | Templates are ranked in descending order of normalized Z-score, as explained by (i) below.
(b) | PDB Hit is the PDB of the specific domain/chain aligned to the query.
(c) | RCSB Link is the RCSB PDB link of the full-length protein.
(d) | CMO is the contact map overlap score, calculated from the number of overlapping contacts between the predicted contact map and the contact map derived from the aligned template, then normalized by the number of predicted contacts.
(e) | MAE is the mean absolute error between the predicted distance map and the distance map derived from the aligned template.
(f) | ID1 is the number of template residues identical to query divided by the number of aligned residues.
(g) | ID2 is the number of template residues identical to query divided by the query sequence length.
(h) | Cov is equal to the number of aligned template residues divided by the query sequence length.
(i) | Norm. Zscore is the normalized Z-score of the threading alignments. A normalized Z-score ≥1 means a good alignment.
(j) | Download PDB provides the structure of the aligned region for each template.
(k) | Download FASTA provides the fasta format and full-length alignment of model and template. Shows alignment for potential ligand binding pockets and GO/EC terms.
(l) | Gene Ontology (GO) term and Enzyme Commission (EC) number list the function annotations for template proteins, as collected by BioLiP database.
(m) | Ligand lists known binding ligands for each template protein, as collected by BioLiP database.
(n) | Binding Site Residues lists the known binding residues for each ligand as collected by BioLiP database. The residue numbering is based on the template PDB numbering and highlighted residues means they are aligned with the query sequence. Note: Listed binding residues may not be representative of the full ligand binding pocket and may be part of a complex with another protein chain/domain. Also, for a single ligand, one template may have multiple binding sites.

Templates from Hybrid-CEthreader

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 5mkl14 | 5mkl | 0.506 | 2.428 | 0.20 | 0.20 | 1.29 | 0.75 | template_1 | template_1 |  |  |  |  |  |
2 | 5mkl11 | 5mkl | 0.478 | 2.481 | 0.18 | 0.18 | 1.21 | 0.70 | template_2 | template_2 |  |  |  |  |  |
3 | 1d3bL | 1d3b | 0.451 | 2.559 | 0.12 | 0.07 | 0.73 | 0.66 | template_3 | template_3 |  |  |  |  |  |
4 | 5uz5K | 5uz5 | 0.448 | 2.188 | 0.17 | 0.14 | 1.01 | 0.66 | template_4 | template_4 | GO:0003723,GO:0005515,GO:0003674 | GO:0000398,GO:0006397,GO:0008380 | GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005634 |  |  |
5 | 6ppnD | 6ppn | 0.448 | 2.094 | 0.24 | 0.15 | 0.72 | 0.66 | template_5 | template_5 |  |  |  |  | NUC | Y35 N37 R62 N64
6 | 6ppnB | 6ppn | 0.441 | 1.985 | 0.25 | 0.17 | 0.76 | 0.64 | template_6 | template_6 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
7 | 6v4xC | 6v4x | 0.444 | 2.131 | 0.22 | 0.16 | 0.93 | 0.64 | template_7 | template_7 |  |  |  |  | NUC NUC | K8 I12 R34 D35 F49 R62 R77 R80 V7 K8 T11 I12 E14 N15 R105 K110
8 | 5nrll | 5nrl | 0.451 | 2.120 | 0.17 | 0.13 | 0.80 | 0.64 | template_8 | template_8 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
9 | 5nrld | 5nrl | 0.438 | 2.223 | 0.23 | 0.14 | 0.67 | 0.62 | template_9 | template_9 | GO:0003723,GO:0005515,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005737,GO:0046540,GO:0071004 |  |  |
10 | 6ppnH | 6ppn | 0.432 | 2.342 | 0.15 | 0.11 | 0.76 | 0.62 | template_10 | template_10 |  |  |  |  | NUC | H30 T31 T32 N33 R61 G62 E63

Templates from SparksX

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 6ppnB | 6ppn | 0.435 | 1.947 | 0.25 | 0.17 | 0.76 | 1.60 | template_1 | template_1 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
2 | 5mkl11 | 5mkl | 0.522 | 2.415 | 0.21 | 0.21 | 1.21 | 1.56 | template_2 | template_2 |  |  |  |  |  |
3 | 5nrll | 5nrl | 0.448 | 2.109 | 0.17 | 0.13 | 0.80 | 1.49 | template_3 | template_3 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
4 | 5mkl14 | 5mkl | 0.534 | 2.396 | 0.21 | 0.21 | 1.29 | 1.47 | template_4 | template_4 |  |  |  |  |  |
5 | 4c8qB | 4c8q | 0.401 | 2.067 | 0.26 | 0.18 | 0.85 | 1.45 | template_5 | template_5 | GO:0003723,GO:0005515 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0000398 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005730,GO:0005732 |  | CO | E28 R78 Y79
6 | 6ppnD | 6ppn | 0.444 | 2.362 | 0.25 | 0.16 | 0.72 | 1.41 | template_6 | template_6 |  |  |  |  | NUC | Y35 N37 R62 N64
7 | 3jb9E | 3jb9 | 0.417 | 2.170 | 0.17 | 0.13 | 0.80 | 1.33 | template_7 | template_7 | GO:0003723,GO:0003674 | GO:0000395,GO:0000398,GO:0006397,GO:0008380 | GO:0005634,GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005681,GO:0005829,GO:0071014 |  | NUC | G1 T2 A29 F30 G32 F33 M34 N35 R58 G59 E60
8 | 5mkiA | 5mki | 0.407 | 2.859 | 0.24 | 0.12 | 0.57 | 1.28 | template_8 | template_8 | GO:0003723 |  |  |  |  |
9 | 5mkl15 | 5mkl | 0.432 | 2.669 | 0.32 | 0.18 | 0.73 | 1.28 | template_9 | template_9 |  |  |  |  |  |
10 | 6ppnH | 6ppn | 0.426 | 2.331 | 0.15 | 0.11 | 0.76 | 1.28 | template_10 | template_10 |  |  |  |  | NUC | H30 T31 T32 N33 R61 G62 E63

Templates from CEthreader

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 5mkl14 | 5mkl | 0.534 | 2.394 | 0.20 | 0.20 | 1.29 | 0.62 | template_1 | template_1 |  |  |  |  |  |
2 | 5mkl11 | 5mkl | 0.534 | 2.366 | 0.24 | 0.24 | 1.21 | 0.61 | template_2 | template_2 |  |  |  |  |  |
3 | 1d3bL | 1d3b | 0.451 | 2.559 | 0.12 | 0.07 | 0.73 | 0.49 | template_3 | template_3 |  |  |  |  |  |
4 | 6ppnD | 6ppn | 0.448 | 2.094 | 0.24 | 0.15 | 0.72 | 0.49 | template_4 | template_4 |  |  |  |  | NUC | Y35 N37 R62 N64
5 | 5uz5K | 5uz5 | 0.448 | 2.188 | 0.17 | 0.14 | 1.01 | 0.49 | template_5 | template_5 | GO:0003723,GO:0005515,GO:0003674 | GO:0000398,GO:0006397,GO:0008380 | GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005634 |  |  |
6 | 5nrll | 5nrl | 0.454 | 2.054 | 0.20 | 0.15 | 0.80 | 0.49 | template_6 | template_6 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
7 | 6ppnB | 6ppn | 0.441 | 1.985 | 0.25 | 0.17 | 0.76 | 0.48 | template_7 | template_7 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
8 | 6v4xC | 6v4x | 0.444 | 2.131 | 0.22 | 0.16 | 0.93 | 0.48 | template_8 | template_8 |  |  |  |  | NUC NUC | K8 I12 R34 D35 F49 R62 R77 R80 V7 K8 T11 I12 E14 N15 R105 K110
9 | 5nrld | 5nrl | 0.438 | 2.223 | 0.23 | 0.14 | 0.67 | 0.48 | template_9 | template_9 | GO:0003723,GO:0005515,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005737,GO:0046540,GO:0071004 |  |  |
10 | 6ppnH | 6ppn | 0.432 | 2.342 | 0.15 | 0.11 | 0.76 | 0.48 | template_10 | template_10 |  |  |  |  | NUC | H30 T31 T32 N33 R61 G62 E63

Templates from HHsearch

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 3jcr2 | 3jcr | 0.386 | 2.244 | 0.28 | 0.18 | 0.73 | 1.32 | template_1 | template_1 | GO:0003723,GO:0005515,GO:0017160,GO:0017070 | GO:0006397,GO:0000398,GO:0008380,GO:0043928 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0071005,GO:0120115,GO:0005654,GO:0005829 |  |  |
2 | 6ppnD | 6ppn | 0.448 | 2.107 | 0.22 | 0.14 | 0.72 | 1.29 | template_2 | template_2 |  |  |  |  | NUC | Y35 N37 R62 N64
3 | 5mkl11 | 5mkl | 0.457 | 2.253 | 0.24 | 0.22 | 1.21 | 1.29 | template_3 | template_3 |  |  |  |  |  |
4 | 6ppnB | 6ppn | 0.435 | 1.975 | 0.25 | 0.17 | 0.76 | 1.29 | template_4 | template_4 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
5 | 4c8qB | 4c8q | 0.401 | 1.968 | 0.24 | 0.16 | 0.85 | 1.29 | template_5 | template_5 | GO:0003723,GO:0005515 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0000398 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005730,GO:0005732 |  | CO | E28 R78 Y79
6 | 3swnA | 3swn | 0.417 | 2.645 | 0.16 | 0.09 | 0.62 | 1.25 | template_6 | template_6 | GO:0003723,GO:0005515,GO:0008266 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0045292,GO:1905323 | GO:0005688,GO:0046540,GO:1990726,GO:0005634,GO:0005681,GO:0005730,GO:0005732,GO:0005697,GO:0120115 |  | ZN | E46 E55 H57
7 | 5nrll | 5nrl | 0.448 | 2.060 | 0.20 | 0.15 | 0.80 | 1.25 | template_7 | template_7 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
8 | 4c8qE | 4c8q | 0.389 | 2.775 | 0.16 | 0.09 | 0.67 | 1.25 | template_8 | template_8 | GO:0003723,GO:0005515 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0000398,GO:0000956 | GO:0005688,GO:0046540,GO:1990726,GO:0005634,GO:0005681,GO:0005730,GO:0005732 |  |  |
9 | 5mqfg | 5mqf | 0.420 | 2.321 | 0.19 | 0.11 | 0.67 | 1.25 | template_9 | template_9 | GO:0003723,GO:1990446,GO:0005515 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0000245,GO:0051170 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0034709,GO:0046540,GO:0071005,GO:0071007,GO:0005654,GO:0030532 |  |  |
10 | 1jbmA | 1jbm | 0.414 | 2.581 | 0.26 | 0.15 | 0.63 | 1.23 | template_10 | template_10 |  | GO:0000398 | GO:0005732 |  |  |

Templates from MapAlign

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 5mkl14 | 5mkl | 0.599 | 2.130 | 0.21 | 0.20 | 1.29 | 0.95 | template_1 | template_1 |  |  |  |  |  |
2 | 5mkl11 | 5mkl | 0.583 | 2.282 | 0.23 | 0.22 | 1.21 | 0.89 | template_2 | template_2 |  |  |  |  |  |
3 | 4xi6A | 4xi6 | 0.506 | 2.853 | 0.11 | 0.10 | 2.95 | 0.66 | template_3 | template_3 | GO:0008270,GO:0004842,GO:0046872 | GO:0016567 |  | 2.3.2.27 | ZN ZN | C79 C82 C103 C106 C94 C97 H112 H116
4 | 5ohqA | 5ohq | 0.503 | 2.809 | 0.12 | 0.10 | 0.89 | 0.66 | template_4 | template_4 |  | GO:0006357,GO:0032784 |  |  |  |
5 | 3dlmA | 3dlm | 0.491 | 2.334 | 0.11 | 0.09 | 1.69 | 0.63 | template_5 | template_5 |  |  |  | 2.1.1.43 |  |
6 | 5uz5K | 5uz5 | 0.481 | 2.511 | 0.20 | 0.15 | 1.01 | 0.63 | template_6 | template_6 | GO:0003723,GO:0005515,GO:0003674 | GO:0000398,GO:0006397,GO:0008380 | GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005634 |  |  |
7 | 7abi7 | 7abi | 0.491 | 3.156 | 0.05 | 0.04 | 1.92 | 0.63 | template_7 | template_7 |  |  |  |  |  |
8 | 2ckkA | 2ckk | 0.491 | 3.003 | 0.06 | 0.05 | 0.98 | 0.61 | template_8 | template_8 |  |  |  |  |  |
9 | 6ppnD | 6ppn | 0.463 | 2.572 | 0.23 | 0.15 | 0.72 | 0.58 | template_9 | template_9 |  |  |  |  | NUC | Y35 N37 R62 N64
10 | 7oqcb | 7oqc | 0.466 | 2.167 | 0.19 | 0.15 | 0.98 | 0.58 | template_10 | template_10 |  |  |  |  |  |

Templates from MUSTER

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 5nrll | 5nrl | 0.454 | 2.064 | 0.18 | 0.14 | 0.80 | 1.31 | template_1 | template_1 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
2 | 4m77A | 4m77 | 0.398 | 2.325 | 0.20 | 0.13 | 0.67 | 1.18 | template_2 | template_2 | GO:0003723,GO:0005515 | GO:0000398,GO:0016070,GO:0006397,GO:0008380,GO:0006364,GO:0008033 | GO:0005688,GO:0046540,GO:0005634,GO:0005681,GO:0005737,GO:0005730 |  |  |
3 | 5mqfg | 5mqf | 0.426 | 2.374 | 0.20 | 0.12 | 0.67 | 1.15 | template_3 | template_3 | GO:0003723,GO:1990446,GO:0005515 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0000245,GO:0051170 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0034709,GO:0046540,GO:0071005,GO:0071007,GO:0005654,GO:0030532 |  |  |
4 | 5ganl | 5gan | 0.373 | 2.207 | 0.22 | 0.15 | 0.74 | 1.14 | template_4 | template_4 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  | NUC | K2 K8 K9 R11 K20 S33 P34 Q35 N37 R61 G62 N63 R66 L79 D82 Q83
5 | 4c8qB | 4c8q | 0.401 | 2.067 | 0.26 | 0.18 | 0.85 | 1.13 | template_5 | template_5 | GO:0003723,GO:0005515 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0000398 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005730,GO:0005732 |  | CO | E28 R78 Y79
6 | 5mqfe | 5mqf | 0.407 | 2.303 | 0.20 | 0.12 | 0.68 | 1.11 | template_6 | template_6 | GO:0003723,GO:0071209,GO:0070034,GO:1990446,GO:0019899,GO:0005515,GO:0071208 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0006479,GO:0006369,GO:0008334,GO:0051170 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0005654,GO:0005683,GO:0005697,GO:0016604,GO:0034709,GO:0046540,GO:0071005,GO:0071007,GO:0030532 |  |  |
7 | 3jb9D | 3jb9 | 0.407 | 2.077 | 0.18 | 0.13 | 0.78 | 1.09 | template_7 | template_7 | GO:0003755,GO:0003723,GO:0005515,GO:0003729 | GO:0000413,GO:0006457,GO:0000395,GO:0006396,GO:0000387,GO:0006397,GO:0008380 | GO:0005681,GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0071004,GO:0005634,GO:0046540,GO:0071014 |  | NUC | N35 N37 R61 G62 K81 P84 R96
8 | 4c8qD | 4c8q | 0.417 | 2.271 | 0.31 | 0.19 | 0.66 | 1.07 | template_8 | template_8 |  | GO:0006396,GO:0000398,GO:0000956 |  |  |  |
9 | 5nrld | 5nrl | 0.438 | 2.286 | 0.21 | 0.13 | 0.67 | 1.07 | template_9 | template_9 | GO:0003723,GO:0005515,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005737,GO:0046540,GO:0071004 |  |  |
10 | 5mkl11 | 5mkl | 0.485 | 2.469 | 0.23 | 0.23 | 1.21 | 1.06 | template_10 | template_10 |  |  |  |  |  |

Templates from MRFsearch

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 3jcr2 | 3jcr | 0.377 | 2.401 | 0.26 | 0.16 | 0.73 | 0.42 | template_1 | template_1 | GO:0003723,GO:0005515,GO:0017160,GO:0017070 | GO:0006397,GO:0000398,GO:0008380,GO:0043928 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0071005,GO:0120115,GO:0005654,GO:0005829 |  |  |
2 | 6v4xC | 6v4x | 0.441 | 2.277 | 0.24 | 0.15 | 0.93 | 0.40 | template_2 | template_2 |  |  |  |  | NUC NUC | K8 I12 R34 D35 F49 R62 R77 R80 V7 K8 T11 I12 E14 N15 R105 K110
3 | 5ganl | 5gan | 0.383 | 2.281 | 0.23 | 0.15 | 0.74 | 0.40 | template_3 | template_3 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  | NUC | K2 K8 K9 R11 K20 S33 P34 Q35 N37 R61 G62 N63 R66 L79 D82 Q83
4 | 5nrll | 5nrl | 0.451 | 2.236 | 0.23 | 0.15 | 0.80 | 0.40 | template_4 | template_4 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
5 | 4c8qB | 4c8q | 0.398 | 2.180 | 0.26 | 0.16 | 0.85 | 0.40 | template_5 | template_5 | GO:0003723,GO:0005515 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0000398 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005730,GO:0005732 |  | CO | E28 R78 Y79
6 | 5mkl11 | 5mkl | 0.457 | 2.197 | 0.25 | 0.20 | 1.21 | 0.40 | template_6 | template_6 |  |  |  |  |  |
7 | 6ppnB | 6ppn | 0.432 | 2.186 | 0.24 | 0.15 | 0.76 | 0.38 | template_7 | template_7 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
8 | 6ppnD | 6ppn | 0.441 | 2.233 | 0.25 | 0.15 | 0.72 | 0.38 | template_8 | template_8 |  |  |  |  | NUC | Y35 N37 R62 N64
9 | 5mkl14 | 5mkl | 0.466 | 2.203 | 0.24 | 0.20 | 1.29 | 0.37 | template_9 | template_9 |  |  |  |  |  |
10 | 5mqfg | 5mqf | 0.426 | 2.355 | 0.21 | 0.12 | 0.67 | 0.35 | template_10 | template_10 | GO:0003723,GO:1990446,GO:0005515 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0000245,GO:0051170 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0034709,GO:0046540,GO:0071005,GO:0071007,GO:0005654,GO:0030532 |  |  |

Templates from DisCovER

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 6ppnD | 6ppn | 0.432 | 2.597 | 0.26 | 0.14 | 0.72 | 0.70 | template_1 | template_1 |  |  |  |  | NUC | Y35 N37 R62 N64
2 | 5nrll | 5nrl | 0.438 | 2.538 | 0.21 | 0.13 | 0.80 | 0.61 | template_2 | template_2 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
3 | 3jb9E | 3jb9 | 0.410 | 2.675 | 0.22 | 0.11 | 0.80 | 0.61 | template_3 | template_3 | GO:0003723,GO:0003674 | GO:0000395,GO:0000398,GO:0006397,GO:0008380 | GO:0005634,GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005681,GO:0005829,GO:0071014 |  | NUC | G1 T2 A29 F30 G32 F33 M34 N35 R58 G59 E60
4 | 1m8vA | 1m8v | 0.407 | 3.030 | 0.27 | 0.13 | 0.59 | 0.61 | template_4 | template_4 |  |  |  |  | NUC NUC NUC U | R3 L5 D6 H9 G32 Y33 D34 A1 R3 D34 H36 H36 N38 R62 D64
5 | 4c8qF | 4c8q | 0.392 | 2.981 | 0.30 | 0.15 | 0.63 | 0.59 | template_5 | template_5 | GO:0003723,GO:0005515 | GO:0000398,GO:0030490,GO:0006397,GO:0008380,GO:0006364,GO:0008033 | GO:0005732,GO:0000932,GO:0005688,GO:0005730,GO:0046540,GO:0005634,GO:0005681,GO:0005737,GO:1990726 |  |  |
6 | 1i5lC | 1i5l | 0.401 | 3.102 | 0.27 | 0.13 | 0.60 | 0.59 | template_6 | template_6 |  |  |  |  | URI | H37 N39 R63 G64 D65
7 | 6ppnB | 6ppn | 0.420 | 2.331 | 0.24 | 0.15 | 0.76 | 0.59 | template_7 | template_7 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
8 | 5mkiA | 5mki | 0.407 | 3.031 | 0.23 | 0.11 | 0.57 | 0.58 | template_8 | template_8 | GO:0003723 |  |  |  |  |
9 | 5nrld | 5nrl | 0.435 | 2.510 | 0.22 | 0.12 | 0.67 | 0.57 | template_9 | template_9 | GO:0003723,GO:0005515,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005737,GO:0046540,GO:0071004 |  |  |
10 | 5mkl12 | 5mkl | 0.423 | 2.639 | 0.31 | 0.17 | 0.64 | 0.57 | template_10 | template_10 |  |  |  |  |  |

Templates from FFAS3D

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 6ppnB | 6ppn | 0.444 | 2.199 | 0.26 | 0.16 | 0.76 | 1.12 | template_1 | template_1 |  |  |  |  | NUC | F35 L36 N37 R63 G64 S65
2 | 4c8qB | 4c8q | 0.383 | 2.427 | 0.28 | 0.18 | 0.85 | 1.09 | template_2 | template_2 | GO:0003723,GO:0005515 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0000398 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005730,GO:0005732 |  | CO | E28 R78 Y79
3 | 6ppnD | 6ppn | 0.426 | 2.507 | 0.24 | 0.15 | 0.72 | 1.08 | template_3 | template_3 |  |  |  |  | NUC | Y35 N37 R62 N64
4 | 5nrll | 5nrl | 0.423 | 2.513 | 0.18 | 0.11 | 0.80 | 1.06 | template_4 | template_4 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
5 | 3jcr2 | 3jcr | 0.377 | 2.486 | 0.29 | 0.19 | 0.73 | 1.02 | template_5 | template_5 | GO:0003723,GO:0005515,GO:0017160,GO:0017070 | GO:0006397,GO:0000398,GO:0008380,GO:0043928 | GO:0000932,GO:0005688,GO:0046540,GO:1990726,GO:0071013,GO:0005634,GO:0005681,GO:0071005,GO:0120115,GO:0005654,GO:0005829 |  |  |
6 | 5mkl15 | 5mkl | 0.398 | 3.061 | 0.30 | 0.16 | 0.73 | 0.99 | template_6 | template_6 |  |  |  |  |  |
7 | 5mqfe | 5mqf | 0.370 | 2.934 | 0.19 | 0.11 | 0.68 | 0.99 | template_7 | template_7 | GO:0003723,GO:0071209,GO:0070034,GO:1990446,GO:0019899,GO:0005515,GO:0071208 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0006479,GO:0006369,GO:0008334,GO:0051170 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0005654,GO:0005683,GO:0005697,GO:0016604,GO:0034709,GO:0046540,GO:0071005,GO:0071007,GO:0030532 |  |  |
8 | 5mqfg | 5mqf | 0.404 | 2.606 | 0.18 | 0.11 | 0.67 | 0.99 | template_8 | template_8 | GO:0003723,GO:1990446,GO:0005515 | GO:0000398,GO:0000387,GO:0006397,GO:0008380,GO:0000245,GO:0051170 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0034709,GO:0046540,GO:0071005,GO:0071007,GO:0005654,GO:0030532 |  |  |
9 | 5gann | 5gan | 0.377 | 2.966 | 0.19 | 0.11 | 0.67 | 0.98 | template_9 | template_9 | GO:0003723,GO:0005515,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005737,GO:0046540,GO:0071004 |  | NUC | N1 S36 N38 R62 G63 S64
10 | 5nrld | 5nrl | 0.407 | 2.871 | 0.19 | 0.11 | 0.67 | 0.98 | template_10 | template_10 | GO:0003723,GO:0005515,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005737,GO:0046540,GO:0071004 |  |  |

Templates from EigenThreader

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 5uz5K | 5uz5 | 0.444 | 2.364 | 0.18 | 0.14 | 1.01 | 0.75 | template_1 | template_1 | GO:0003723,GO:0005515,GO:0003674 | GO:0000398,GO:0006397,GO:0008380 | GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005634 |  |  |
2 | 1pzdA | 1pzd | 0.389 | 2.675 | 0.08 | 0.07 | 2.20 | 0.73 | template_2 | template_2 | GO:0005198 | GO:0006886,GO:0016192 | GO:0030117,GO:0030126 |  |  |
3 | 5nrll | 5nrl | 0.494 | 2.388 | 0.18 | 0.13 | 0.80 | 0.73 | template_3 | template_3 | GO:0003723,GO:0003729 | GO:0000387,GO:0006397,GO:0008380,GO:0000398 | GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0005634,GO:0005829,GO:0046540,GO:0071004,GO:0030532 |  |  |
4 | 5mkl11 | 5mkl | 0.522 | 2.180 | 0.22 | 0.19 | 1.21 | 0.73 | template_4 | template_4 |  |  |  |  |  |
5 | 4m75A | 4m75 | 0.438 | 2.466 | 0.14 | 0.11 | 1.08 | 0.73 | template_5 | template_5 |  | GO:0000956 |  |  |  |
6 | 4a53A | 4a53 | 0.327 | 2.946 | 0.14 | 0.11 | 1.02 | 0.73 | template_6 | template_6 | GO:0003729 | GO:0031087 |  |  |  |
7 | 5mkl14 | 5mkl | 0.500 | 2.300 | 0.18 | 0.16 | 1.29 | 0.72 | template_7 | template_7 |  |  |  |  |  |
8 | 3jb9E | 3jb9 | 0.346 | 2.574 | 0.15 | 0.11 | 0.80 | 0.70 | template_8 | template_8 | GO:0003723,GO:0003674 | GO:0000395,GO:0000398,GO:0006397,GO:0008380 | GO:0005634,GO:0005737,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071004,GO:0005687,GO:0071013,GO:0005681,GO:0005829,GO:0071014 |  | NUC | G1 T2 A29 F30 G32 F33 M34 N35 R58 G59 E60
9 | 7oqcb | 7oqc | 0.429 | 2.607 | 0.16 | 0.12 | 0.98 | 0.70 | template_9 | template_9 |  |  |  |  |  |
10 | 3jb9D | 3jb9 | 0.435 | 2.436 | 0.18 | 0.13 | 0.78 | 0.67 | template_10 | template_10 | GO:0003755,GO:0003723,GO:0005515,GO:0003729 | GO:0000413,GO:0006457,GO:0000395,GO:0006396,GO:0000387,GO:0006397,GO:0008380 | GO:0005681,GO:0005686,GO:0005685,GO:0000243,GO:0005682,GO:0005687,GO:0005689,GO:0034715,GO:0034719,GO:0071013,GO:0071004,GO:0005634,GO:0046540,GO:0071014 |  | NUC | N35 N37 R61 G62 K81 P84 R96

Templates from HHpred

Rank | PDB Hit | RCSB Link | CMO | MAE | ID1 | ID2 | Cov | Norm. Zscore | Download PDB | Download FASTA | Gene_Ontology_(GO)_term (Molecular_Function) | Gene_Ontology_(GO)_term (Biological_Process) | Gene_Ontology_(GO)_term (Cellular_Componenet) | Enzyme_Commission (EC)_number | Ligand | Binding site residues
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
1 | 5mkl11 | 5mkl | 0.349 | 3.250 | 0.24 | 0.21 | 1.21 | 1.24 | template_1 | template_1 |  |  |  |  |  |
2 | 6v4xC | 6v4x | 0.426 | 2.196 | 0.23 | 0.15 | 0.93 | 1.22 | template_2 | template_2 |  |  |  |  | NUC NUC | K8 I12 R34 D35 F49 R62 R77 R80 V7 K8 T11 I12 E14 N15 R105 K110
3 | 4gouA1 | 4gou | 0.028 | 39.121 | 0.17 | 0.02 | 0.63 | 0.23 | template_3 | template_3 | GO:0005515,GO:0005089 | GO:0035023 |  |  |  |
4 | 1y96A | 1y96 | 0.404 | 2.880 | 0.22 | 0.14 | 0.70 | 1.19 | template_4 | template_4 |  | GO:0000245 | GO:0005634 |  |  |
5 | 3swnA | 3swn | 0.417 | 2.645 | 0.16 | 0.09 | 0.62 | 1.22 | template_5 | template_5 | GO:0003723,GO:0005515,GO:0008266 | GO:0006397,GO:0008380,GO:0006364,GO:0008033,GO:0045292,GO:1905323 | GO:0005688,GO:0046540,GO:1990726,GO:0005634,GO:0005681,GO:0005730,GO:0005732,GO:0005697,GO:0120115 |  | ZN | E46 E55 H57
6 | 2fwkA | 2fwk | 0.410 | 2.695 | 0.16 | 0.09 | 0.63 | 1.34 | template_6 | template_6 |  |  |  |  |  |
7 | 1m8vA | 1m8v | 0.435 | 2.705 | 0.27 | 0.14 | 0.59 | 1.20 | template_7 | template_7 |  |  |  |  | NUC NUC NUC U | R3 L5 D6 H9 G32 Y33 D34 A1 R3 D34 H36 H36 N38 R62 D64
8 | 3cw1C | 3cw1 | 0.383 | 2.866 | 0.17 | 0.09 | 0.72 | 1.21 | template_8 | template_8 | GO:0005515,GO:0003723 | GO:0008380,GO:0000398,GO:0000387,GO:0006397,GO:0000245,GO:0051170 | GO:0030532,GO:0005686,GO:0005685,GO:0005682,GO:0046540,GO:0071013,GO:0005634,GO:0005681,GO:0005737,GO:0005829,GO:0070062,GO:0005687,GO:0005689,GO:0034709,GO:0034715,GO:0034719,GO:0071005,GO:0071007,GO:0005654 |  |  |
9 | 5mkiA | 5mki | 0.407 | 2.934 | 0.24 | 0.12 | 0.57 | 1.25 | template_9 | template_9 | GO:0003723 |  |  |  |  |
10 | 5ganr | 5gan | 0.377 | 2.773 | 0.18 | 0.10 | 0.56 | 1.21 | template_10 | template_10 | GO:0003723,GO:0005515,GO:0003674 | GO:0006397,GO:0008380,GO:0000398 | GO:0071004,GO:0005689,GO:0071013,GO:0005686,GO:0005685,GO:0005682,GO:0005687,GO:0034719,GO:0043186,GO:0005634,GO:0005681,GO:0046540 |  | NUC | N19 L35 N36 R57 G58

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References:
1. | W Zheng, Q Wuyun, X Zhou, Y Li, P Freddolino, Y Zhang. LOMETS3: Integrating deep-learning and profile-alignment for advanced protein template recognition and function annotation. Nucleic Acids Research, 50: W454-W464 (2022)
2. | W Zheng, C Zhang, Q Wuyun, R Pearce, Y Li, Y Zhang. LOMETS2: improved meta-threading server for fold-recognition and structure-based function annotation for distant-homology proteins. Nucleic Acids Research, 47: W429-W436 (2019).
3. | S Wu, Y Zhang. LOMETS: A local meta-threading-server for protein structure prediction. Nucleic Acids Research, 35: 3375-3382 (2007).