StarFunc result for job id O95153

User Input

>input (1857 residues)
MEQLTTLPRPGDPGAMEPWALPTWHSWTPGRGGEPSSAAPSIADTPPAALQLQELRSEES
SKPKGDGSSRPVGGTDPEGAEACLPSLGQQASSSGPACQRPEDEEVEAFLKAKLNMSFGD
RPNLELLRALGELRQRCAILKEENQMLRKSSFPETEEKVRRLKRKNAELAVIAKRLEERA
RKLQETNLRVVSAPLPRPGTSLELCRKALARQRARDLSETASALLAKDKQIAALQRECRE
LQARLTLVGKEGPQWLHVRDFDRLLRESQREVLRLQRQIALRNQRETLPLPPSWPPGPAL
QARAGAPAPGAPGEATPQEDADNLPVILGEPEKEQRVQQLESELSKKRKKCESLEQEARK
KQRRCEELELQLRQAQNENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSA
LRKSQGLQSKLESLEQVLKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQ
REHEGAVQLLESTLDSMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPGPLDLLTSALD
CGSLGDCPPPPCCCSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKK
AESLSNSSHSESIHNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLA
RYSYNPFEGPNENPEAELPLTAGEYIYIYGNMDEDGFFEGELMDGRRGLVPSNFVERVSD
DDLLTSLPPELADLSHSSGPELSFLSVGGGGSSSGGQSSVGRSQPRPEEEDAGDELSLSP
SPEGLGEPPAVPYPRRLVVLKQLAHSVVLAWEPPPEQVELHGFHICVNGELRQALGPGAP
PKAVLENLDLWAGPLHISVQALTSRGSSDPLRCCLAVGARAGVVPSQLRVHRLTATSAEI
TWVPGNSNLAHAIYLNGEECPPASPSTYWATFCHLRPGTPYQAQVEAQLPPQGPWEPGWE
RLEQRAATLQFTTLPAGPPDAPLDVQIEPGPSPGILIISWLPVTIDAAGTSNGVRVTGYA
IYADGQKIMEVASPTAGSVLVELSQLQLLQVCREVVVRTMSPHGESADSIPAPITPALAP
ASLPARVSCPSPHPSPEARAPLASASPGPGDPSSPLQHPAPLGTQEPPGAPPASPSREMA
KGSHEDPPAPCSQEEAGAAVLGTSEERTASTSTLGEKDPGPAAPSLAKQEAEWTAGEACP
ASSSTQGARAQQAPNTEMCQGGDPGSGLRPRAEKEDTAELGVHLVNSLVDHGRNSDLSDI
QEEEEEEEEEEEEELGSRTCSFQKQVAGNSIRENGAKSQPDPFCETDSDEEILEQILELP
LQQFCSKKLFSIPEEEEEEEEDEEEEKSGAGCSSRDPGPPEPALLGLGCDSGQPRRPGQC
PLSPESSRAGDCLEDMPGLVGGSSRRRGGGSPEKPPSRRRPPDPREHCSRLLSNNGPQAS
GRLGPTRERGGLPVIEGPRTGLEASGRGRLGPSRRCSRGRALEPGLASCLSPKCLEISIE
YDSEDEQEAGSGGISITSSCYPGDGEAWGTATVGRPRGPPKANSGPKPYPRLPAWEKGEP
ERRGRSATGRAKEPLSRATETGEARGQDGSGRRGPQKRGVRVLRPSTAELVPARSPSETL
AYQHLPVRIFVALFDYDPVSMSPNPDAGEEELPFREGQILKVFGDKDADGFYQGEGGGRT
GYIPCNMVAEVAVDSPAGRQQLLQRGYLSPDILLEGSGNGPFVYSTAHTTGPPPKPRRSK
KAESEGPAQPCPGPPKLVPSADLKAPHSMVAAFDYNPQESSPNMDVEAELPFRAGDVITV
FGGMDDDGFYYGELNGQRGLVPSNFLEGPGPEAGGLDREPRTPQAESQRTRRRRVQC

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:O95153	1.000	1.000	0.000	1857	1.000	1.000	O95153.pdb.gz	RIMB1_HUMAN Peripheral-type benzodiazepine receptor-associated protein 1 OS=Homo sapiens OX=9606 GN=TSPOAP1 PE=1 SV=2
2	AFDB:Q9JIR0	0.237	0.238	0.000	1847	0.801	0.805	Q9JIR0.pdb.gz	RIMB1_RAT Peripheral-type benzodiazepine receptor-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Tspoap1 PE=1 SV=2
3	AFDB:Q9UFD9	0.109	0.122	1.489E-75	1639	0.288	0.326	Q9UFD9.pdb.gz	RIM3A_HUMAN RIMS-binding protein 3A OS=Homo sapiens OX=9606 GN=RIMBP3 PE=1 SV=4
4	AFDB:Q3V0F0	0.110	0.125	5.759E-74	1606	0.267	0.308	Q3V0F0.pdb.gz	RIMB3_MOUSE RIMS-binding protein 3 OS=Mus musculus OX=10090 GN=Rimbp3 PE=1 SV=2
5	AFDB:A0A0B4JDC9	0.143	0.144	2.842E-57	1844	0.178	0.180	A0A0B4JDC9.pdb.gz	A0A0B4JDC9_DROME RIM-binding protein, isoform F OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=1
6	AFDB:Q96MS0	0.065	0.083	9.141E-17	1386	0.096	0.128	Q96MS0.pdb.gz	ROBO3_HUMAN Roundabout homolog 3 OS=Homo sapiens OX=9606 GN=ROBO3 PE=1 SV=2
7	AFDB:P97798	0.056	0.068	1.565E-16	1493	0.073	0.090	P97798.pdb.gz	NEO1_MOUSE Neogenin OS=Mus musculus OX=10090 GN=Neo1 PE=1 SV=2
8	AFDB:O35158	0.055	0.077	2.280E-16	1256	0.066	0.097	O35158.pdb.gz	CDON_RAT Cell adhesion molecule-related/down-regulated by oncogenes OS=Rattus norvegicus OX=10116 GN=Cdon PE=1 SV=2
9	AFDB:P97603	0.076	0.095	2.827E-16	1377	0.059	0.080	P97603.pdb.gz	NEO1_RAT Neogenin (Fragment) OS=Rattus norvegicus OX=10116 GN=Neo1 PE=1 SV=1
10	AFDB:Q9Z2I4	0.068	0.088	3.903E-16	1366	0.083	0.113	Q9Z2I4.pdb.gz	ROBO3_MOUSE Roundabout homolog 3 OS=Mus musculus OX=10090 GN=Robo3 PE=1 SV=2
11	PDB:8eyyA	0.061	0.123	4.169E-12	775	0.031	0.074	8eyyA.pdb.gz
12	PDB:6pxvA	0.061	0.115	3.812E-10	823	0.031	0.069	6pxvA.pdb.gz
13	PDB:8dtlA	0.061	0.123	1.717E-9	741	0.030	0.076	8dtlA.pdb.gz
14	PDB:6pyhD	0.059	0.112	1.812E-9	798	0.027	0.063	6pyhD.pdb.gz
15	PDB:2lqnA	0.049	0.188	1.267E-7	303	0.027	0.165	2lqnA.pdb.gz
16	PDB:7z0lB	0.063	0.207	4.857E-7	370	0.017	0.086	7z0lB.pdb.gz
17	PDB:7u7nC	0.066	0.363	7.534E-6	200	0.017	0.160	7u7nC.pdb.gz
18	PDB:1e07A	0.059	0.129	1.158E-5	642	0.016	0.045	1e07A.pdb.gz
19	PDB:5mj3A	0.065	0.243	1.158E-5	302	0.022	0.136	5mj3A.pdb.gz
20	PDB:7bwaA	0.047	0.113	1.158E-5	674	0.020	0.055	7bwaA.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	O95153	0.0	3690	1857	1.000	1.000	RIMB1_HUMAN Peripheral-type benzodiazepine receptor-associated protein 1 OS=Homo sapiens OX=9606 GN=TSPOAP1 PE=1 SV=2
2	Q7TNF8	0.0	2828	1846	0.822	0.827	RIMB1_MOUSE Peripheral-type benzodiazepine receptor-associated protein 1 OS=Mus musculus OX=10090 GN=Tspoap1 PE=2 SV=2
3	Q9JIR0	0.0	2737	1847	0.803	0.807	RIMB1_RAT Peripheral-type benzodiazepine receptor-associated protein 1 OS=Rattus norvegicus OX=10116 GN=Tspoap1 PE=1 SV=2
4	Q80U40	2.95e-130	438	1072	0.146	0.253	RIMB2_MOUSE RIMS-binding protein 2 OS=Mus musculus OX=10090 GN=Rimbp2 PE=1 SV=3
5	O15034	2.85e-120	409	1052	0.135	0.238	RIMB2_HUMAN RIMS-binding protein 2 OS=Homo sapiens OX=9606 GN=RIMBP2 PE=1 SV=3
6	Q9JIR1	4.24e-98	344	1049	0.103	0.183	RIMB2_RAT RIMS-binding protein 2 OS=Rattus norvegicus OX=10116 GN=Rimbp2 PE=1 SV=2
7	Q9N415	1.12e-54	213	1276	0.078	0.113	Q9N415_CAEEL Variant SH3 domain protein OS=Caenorhabditis elegans OX=6239 GN=rimb-1 PE=1 SV=3
8	Q9UFD9	1.38e-52	207	1639	0.079	0.090	RIM3A_HUMAN RIMS-binding protein 3A OS=Homo sapiens OX=9606 GN=RIMBP3 PE=1 SV=4
9	A0A126GUV2	6.17e-49	195	1765	0.081	0.085	A0A126GUV2_DROME RIM-binding protein, isoform M OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=1
10	A0A0B4KGQ6	6.60e-49	195	1763	0.081	0.085	A0A0B4KGQ6_DROME RIM-binding protein, isoform J OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=1
11	Q86BS0	7.66e-49	194	1473	0.081	0.103	Q86BS0_DROME RIM-binding protein, isoform O OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=3
12	A0A0B4JDC9	7.76e-49	194	1844	0.081	0.082	A0A0B4JDC9_DROME RIM-binding protein, isoform F OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=1
13	Q9VF66	8.15e-49	194	1748	0.081	0.086	Q9VF66_DROME RIM-binding protein, isoform K OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=5
14	E1JIL7	8.72e-49	194	1791	0.081	0.084	E1JIL7_DROME RIM-binding protein, isoform N OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=3
15	A0A0B4JCX2	8.91e-49	194	1817	0.081	0.083	A0A0B4JCX2_DROME RIM-binding protein, isoform G OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=1
16	Q86BP0	1.32e-47	190	1487	0.080	0.100	Q86BP0_DROME RIM-binding protein, isoform L OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=3
17	A0A0B4KG12	2.44e-47	189	1799	0.080	0.083	A0A0B4KG12_DROME RIM-binding protein, isoform I OS=Drosophila melanogaster OX=7227 GN=Rbp PE=1 SV=1
18	Q3V0F0	1.37e-46	187	1606	0.052	0.060	RIMB3_MOUSE RIMS-binding protein 3 OS=Mus musculus OX=10090 GN=Rimbp3 PE=1 SV=2
19	Q9JLQ0	5.81e-08	60.1	637	0.029	0.085	CD2AP_MOUSE CD2-associated protein OS=Mus musculus OX=10090 GN=Cd2ap PE=1 SV=3
20	P29355	7.84e-08	57.4	228	0.032	0.263	SEM5_CAEEL Sex muscle abnormal protein 5 OS=Caenorhabditis elegans OX=6239 GN=sem-5 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00041 fn3	0.14	23.8	Fibronectin type III domain
2	PF00018 SH3_1	1.5e-11	55.0	SH3 domain
3	PF07653 SH3_2	4.7e-33	124.1	Variant SH3 domain
4	PF14604 SH3_9	2.4e-27	105.9	Variant SH3 domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000345824

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000428417	0.983	Regulating synaptic membrane exocytosis protein 1
2	9606.ENSP00000262231	0.958	Regulating synaptic membrane exocytosis protein 2
3	9606.ENSP00000379563	0.957	Translocator protein
4	9606.ENSP00000367756	0.949	Protein unc-13 homolog B
5	9606.ENSP00000265381	0.921	Amyloid-beta A4 precursor protein-binding family A member 1
6	9606.ENSP00000221459	0.915	Protein lin-7 homolog B
7	9606.ENSP00000278193	0.914	Protein lin-7 homolog C
8	9606.ENSP00000367408	0.912	Peripheral plasma membrane protein CASK
9	9606.ENSP00000447488	0.903	Protein lin-7 homolog A
10	9606.ENSP00000222256	0.877	Ras-related protein Rab-3A
11	9606.ENSP00000241014	0.802	C-Jun-amino-terminal kinase-interacting protein 1
12	9606.ENSP00000282878	0.802	Ras-related protein Rab-3C
13	9606.ENSP00000450337	0.791	Liprin-alpha-2
14	9606.ENSP00000335614	0.761	Liprin-alpha-3
15	9606.ENSP00000355777	0.751	Golgi resident protein GCP60
16	9606.ENSP00000253925	0.749	Liprin-alpha-1
17	9606.ENSP00000261205	0.724	Synaptotagmin-1
18	9606.ENSP00000272198	0.715	Liprin-alpha-4
19	9606.ENSP00000222812	0.707	Syntaxin-1A
20	9606.ENSP00000295987	0.688	Synapsin-1

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005102	0.998	signaling receptor binding
GO:0030156	0.630	benzodiazepine receptor binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0050794	0.958	regulation of cellular process
GO:0009987	0.954	cellular process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	0.997	cytosol
GO:0043231	0.997	intracellular membrane-bounded organelle
GO:0005739	0.931	mitochondrion
GO:0030054	0.787	cell junction
GO:0071944	0.754	cell periphery
GO:0045202	0.727	synapse
GO:0098793	0.704	presynapse
GO:0016020	0.675	membrane
GO:0005886	0.578	plasma membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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