StarFunc result for job id P08708

User Input

>input (135 residues)
MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKR
IQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVT
QPTVGMNFKTPRGPV

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P04644	0.837	0.837	7.327E-22	135	0.985	0.985	P04644.pdb.gz	RS17_RAT Small ribosomal subunit protein eS17 OS=Rattus norvegicus OX=10116 GN=Rps17 PE=1 SV=3
2	PDB:6qzpSR	0.800	0.800	6.207E-19	135	1.000	1.000	6qzpSR.pdb.gz	Visualization of chemical modifications in the human 80S ribosome structure.
3	AFDB:P17704	0.845	0.869	1.137E-17	131	0.748	0.771	P17704.pdb.gz	RS17_DROME Small ribosomal subunit protein eS17 OS=Drosophila melanogaster OX=7227 GN=RpS17 PE=1 SV=2
4	AFDB:P49205	0.782	0.753	2.511E-16	141	0.600	0.574	P49205.pdb.gz	RS171_ARATH Small ribosomal subunit protein eS17z OS=Arabidopsis thaliana OX=3702 GN=RPS17A PE=2 SV=3
5	AFDB:Q9SQZ1	0.811	0.785	3.201E-16	140	0.585	0.564	Q9SQZ1.pdb.gz	RS173_ARATH Small ribosomal subunit protein eS17x OS=Arabidopsis thaliana OX=3702 GN=RPS17C PE=2 SV=3
6	AFDB:O42984	0.860	0.885	4.607E-16	131	0.622	0.641	O42984.pdb.gz	RS17A_SCHPO Small ribosomal subunit protein eS17A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps1701 PE=3 SV=1
7	AFDB:Q9P7J6	0.836	0.853	8.982E-16	132	0.630	0.644	Q9P7J6.pdb.gz	RS17B_SCHPO Small ribosomal subunit protein eS17B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps1702 PE=1 SV=1
8	AFDB:P02407	0.860	0.854	4.640E-14	136	0.578	0.574	P02407.pdb.gz	RS17A_YEAST Small ribosomal subunit protein eS17A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS17A PE=1 SV=1
9	AFDB:Q382Z8	0.726	0.695	4.640E-14	142	0.541	0.514	Q382Z8.pdb.gz	Q382Z8_TRYB2 40S ribosomal protein S17, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.3675 PE=1 SV=1
10	PDB:4v6wAR	0.678	0.750	2.260E-13	120	0.719	0.808	4v6wAR.pdb.gz	Structures of the human and Drosophila 80S ribosome.
11	PDB:4v8mAL	0.674	0.714	5.343E-10	126	0.526	0.563	4v8mAL.pdb.gz	High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
12	PDB:4v6iAQ	0.351	0.349	4.818E-5	136	0.556	0.551	4v6iAQ.pdb.gz	Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
13	AFDB:P15375	0.160	0.105	9.478E-1	242	0.156	0.087	P15375.pdb.gz	MYF6_MOUSE Myogenic factor 6 OS=Mus musculus OX=10090 GN=Myf6 PE=2 SV=1
14	PDB:6hizCI	0.203	0.141	1.013	222	0.148	0.090	6hizCI.pdb.gz	Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
15	AFDB:P40522	0.285	0.080	1.208	640	0.104	0.022	P40522.pdb.gz	VHR1_YEAST Transcription factor VHR1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=VHR1 PE=1 SV=1
16	PDB:4ob3B	0.205	0.139	1.372	229	0.156	0.092	4ob3B.pdb.gz	The active site sulfenic acid ligand in nitrile hydratases can function as a nucleophile.
17	PDB:1ykbD	0.201	0.194	2.368	142	0.074	0.070	1ykbD.pdb.gz	Structure of insect-cell-derived IL-22.
18	PDB:3j6bL	0.232	0.151	2.841	229	0.067	0.039	3j6bL.pdb.gz	Structure of the yeast mitochondrial large ribosomal subunit.
19	PDB:1ax8A	0.178	0.183	3.408	130	0.096	0.100	1ax8A.pdb.gz
20	PDB:3rj1O	0.210	0.256	3.848	94	0.096	0.138	3rj1O.pdb.gz	Architecture of the Mediator head module.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P08708	5.08e-97	276	135	1.000	1.000	RS17_HUMAN Small ribosomal subunit protein eS17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2
2	P63276	4.00e-96	274	135	0.993	0.993	RS17_MOUSE Small ribosomal subunit protein eS17 OS=Mus musculus OX=10090 GN=Rps17 PE=1 SV=2
3	Q6QAP7	4.00e-96	274	135	0.993	0.993	RS17_PIG Small ribosomal subunit protein eS17 OS=Sus scrofa OX=9823 GN=RPS17 PE=1 SV=3
4	P04644	2.50e-95	272	135	0.985	0.985	RS17_RAT Small ribosomal subunit protein eS17 OS=Rattus norvegicus OX=10116 GN=Rps17 PE=1 SV=3
5	P17704	1.45e-68	204	131	0.748	0.771	RS17_DROME Small ribosomal subunit protein eS17 OS=Drosophila melanogaster OX=7227 GN=RpS17 PE=1 SV=2
6	Q9P7J6	4.54e-56	173	132	0.652	0.667	RS17B_SCHPO Small ribosomal subunit protein eS17B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps1702 PE=1 SV=1
7	O42984	6.42e-54	167	131	0.600	0.618	RS17A_SCHPO Small ribosomal subunit protein eS17A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps1701 PE=3 SV=1
8	Q9SJ36	4.27e-53	166	140	0.585	0.564	RS172_ARATH Small ribosomal subunit protein eS17y OS=Arabidopsis thaliana OX=3702 GN=RPS17B PE=2 SV=3
9	Q9SQZ1	2.35e-52	164	140	0.600	0.579	RS173_ARATH Small ribosomal subunit protein eS17x OS=Arabidopsis thaliana OX=3702 GN=RPS17C PE=2 SV=3
10	Q9LZ17	4.68e-52	163	141	0.578	0.553	RS174_ARATH Small ribosomal subunit protein eS17w OS=Arabidopsis thaliana OX=3702 GN=RPS17D PE=2 SV=3
11	P49205	2.01e-51	161	141	0.578	0.553	RS171_ARATH Small ribosomal subunit protein eS17z OS=Arabidopsis thaliana OX=3702 GN=RPS17A PE=2 SV=3
12	P14127	1.84e-49	156	136	0.563	0.559	RS17B_YEAST Small ribosomal subunit protein eS17B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS17B PE=1 SV=1
13	P02407	1.98e-49	156	136	0.563	0.559	RS17A_YEAST Small ribosomal subunit protein eS17A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS17A PE=1 SV=1
14	Q6FMQ4	8.59e-49	154	136	0.548	0.544	Q6FMQ4_CANGA Candida glabrata strain CBS138 chromosome K complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=CAGL0K06149g PE=3 SV=1
15	Q382Z8	1.84e-44	144	142	0.519	0.493	Q382Z8_TRYB2 40S ribosomal protein S17, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.3675 PE=1 SV=1
16	P38615	0.49	32.0	370	0.170	0.062	RIM11_YEAST Serine/threonine-protein kinase RIM11/MSD1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RIM11 PE=1 SV=1
17	Q9X519	0.80	31.6	511	0.148	0.039	GPMI_GEOSE 2,3-bisphosphoglycerate-independent phosphoglycerate mutase OS=Geobacillus stearothermophilus OX=1422 GN=gpmI PE=1 SV=3
18	Q8TCU6	1.5	30.8	1659	0.133	0.011	PREX1_HUMAN Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein OS=Homo sapiens OX=9606 GN=PREX1 PE=1 SV=3
19	A0A3B3ITW1	2.9	30.0	387	0.193	0.067	A0A3B3ITW1_HUMAN [tau protein] kinase OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2
20	F1NPL8	3.1	29.6	399	0.193	0.065	F1NPL8_CHICK [tau protein] kinase OS=Gallus gallus OX=9031 GN=GSK3A PE=1 SV=4

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00833 Ribosomal_S17e	3.2e-64	225.8	Ribosomal S17

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 61622.XP_010385794.1

Rank	PPI partner	STRING score	Description
1	61622.XP_010362242.1	0.998	Belongs to the eukaryotic ribosomal protein eS30 family.
2	61622.XP_010365097.1	0.995	Belongs to the universal ribosomal protein uS3 family.
3	61622.XP_010373201.1	0.995	Belongs to the universal ribosomal protein uS19 family.
4	61622.XP_010378210.1	0.995	Ribosomal protein S28
5	61622.XP_010356159.1	0.994	Belongs to the universal ribosomal protein uS13 family.
6	61622.XP_010356212.1	0.994	Belongs to the eukaryotic ribosomal protein eS7 family.
7	61622.XP_010360841.1	0.994	40S ribosomal protein S20
8	61622.XP_010364012.1	0.994	Belongs to the eukaryotic ribosomal protein eS6 family.
9	61622.XP_010368731.1	0.994	Belongs to the universal ribosomal protein uS8 family.
10	61622.XP_010371946.1	0.994	Belongs to the universal ribosomal protein uS11 family.
11	61622.XP_010384342.1	0.994	Belongs to the universal ribosomal protein uS12 family.
12	61622.XP_010385257.1	0.994	Belongs to the universal ribosomal protein uS7 family.
13	61622.XP_010351555.1	0.993	Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 1 mRNA, 138 ESTs, 36 Proteins, and 37% coverage of the annotated genomic feature by RNAseq alignments
14	61622.XP_010363500.1	0.993	Belongs to the eukaryotic ribosomal protein eS21 family.
15	61622.XP_010376465.1	0.993	ubiquitin-40S ribosomal protein S27a
16	61622.XP_010378976.1	0.993	Belongs to the universal ribosomal protein uS4 family.
17	61622.XP_010387805.1	0.993	Ribosomal protein S29
18	61622.XP_010370819.1	0.992	May play a role during erythropoiesis through regulation of transcription factor DDIT3
19	61622.XP_010361541.1	0.991	Belongs to the eukaryotic ribosomal protein eS24 family.
20	61622.XP_010382943.1	0.991	Receptor for activated C kinase 1

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003735	1.000	structural constituent of ribosome
GO:0003723	1.000	RNA binding
GO:0005515	0.386	protein binding
GO:0003729	0.300	mRNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0044238	0.996	primary metabolic process
GO:0044237	0.996	cellular metabolic process
GO:0006807	0.995	nitrogen compound metabolic process
GO:0043170	0.995	macromolecule metabolic process
GO:0006412	0.993	translation
GO:0002181	0.961	cytoplasmic translation
GO:0071840	0.945	cellular component organization or biogenesis
GO:0022613	0.906	ribonucleoprotein complex biogenesis
GO:0042254	0.357	ribosome biogenesis
GO:0006139	0.325	nucleobase-containing compound metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	0.998	cytosol
GO:0044391	0.995	ribosomal subunit
GO:0043231	0.994	intracellular membrane-bounded organelle
GO:0016020	0.993	membrane
GO:0022626	0.985	cytosolic ribosome
GO:0022627	0.975	cytosolic small ribosomal subunit
GO:0005634	0.915	nucleus
GO:0070013	0.898	intracellular organelle lumen
GO:0031981	0.835	nuclear lumen
GO:0005654	0.804	nucleoplasm
GO:0030054	0.759	cell junction
GO:0012505	0.546	endomembrane system
GO:0065010	0.347	extracellular membrane-bounded organelle

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

[back to server]