StarFunc result for job id P0CJ77

User Input

>input (24 residues)
MTTRGFSCLLLLIREIDLSAKRRI

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Click to view	Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q8IVG9	3.27e-05	36.6	24	0.708	0.708	HUNIN_HUMAN Humanin OS=Homo sapiens OX=9606 GN=MT-RNR2 PE=1 SV=1
2	P0CJ72	1.91e-04	34.7	24	0.667	0.667	HMN5_HUMAN Humanin-like 5 OS=Homo sapiens OX=9606 GN=MTRNR2L5 PE=2 SV=1
3	C0HLU6	7.61e-04	33.5	38	0.625	0.395	HMNL_RAT Humanin-like protein OS=Rattus norvegicus OX=10116 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF15040 Humanin	3.2e-14	63.3	Humanin family

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000442159

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000473686	0.879	Humanin-like 6
2	9606.ENSP00000439228	0.805	Humanin-like 1
3	9606.ENSP00000443339	0.797	Humanin-like 3
4	9606.ENSP00000413150	0.720	Uncharacterized protein C1orf226
5	9606.ENSP00000385592	0.662	Immunoglobulin superfamily member 23
6	9606.ENSP00000382856	0.555	Humanin-like 4
7	9606.ENSP00000229583	0.548	Androgen-dependent TFPI-regulating protein
8	9606.ENSP00000439666	0.526	MT-RNR2 like 8
9	9606.ENSP00000474861	0.523	Humanin-like 11
10	9606.ENSP00000253407	0.505	C1q-related factor

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	0.999	protein binding
GO:0005102	0.799	signaling receptor binding
GO:0098772	0.790	molecular function regulator activity
GO:0030545	0.415	signaling receptor regulator activity
GO:0048019	0.349	receptor antagonist activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

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GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0050789	0.993	regulation of biological process
GO:0050794	0.984	regulation of cellular process
GO:0009987	0.979	cellular process
GO:0048519	0.915	negative regulation of biological process
GO:0050896	0.892	response to stimulus
GO:0048523	0.856	negative regulation of cellular process
GO:0051716	0.805	cellular response to stimulus
GO:0048518	0.796	positive regulation of biological process
GO:0019222	0.786	regulation of metabolic process
GO:0060255	0.760	regulation of macromolecule metabolic process
GO:0051128	0.760	regulation of cellular component organization
GO:0080090	0.748	regulation of primary metabolic process
GO:0051171	0.748	regulation of nitrogen compound metabolic process
GO:0042221	0.745	response to chemical
GO:0031323	0.743	regulation of cellular metabolic process
GO:0070887	0.704	cellular response to chemical stimulus
GO:0051252	0.646	regulation of RNA metabolic process
GO:0031326	0.645	regulation of cellular biosynthetic process
GO:0032502	0.517	developmental process
GO:0008152	0.509	metabolic process
GO:0010468	0.486	regulation of gene expression
GO:0009893	0.480	positive regulation of metabolic process
GO:0048522	0.461	positive regulation of cellular process
GO:0071704	0.454	organic substance metabolic process
GO:0048856	0.444	anatomical structure development
GO:0032501	0.443	multicellular organismal process
GO:0065008	0.433	regulation of biological quality
GO:0010604	0.431	positive regulation of macromolecule metabolic process
GO:0007275	0.425	multicellular organism development
GO:0009719	0.352	response to endogenous stimulus
GO:0071310	0.352	cellular response to organic substance
GO:0010243	0.346	response to organonitrogen compound
GO:0045935	0.343	positive regulation of nucleobase-containing compound metabolic process
GO:0006355	0.342	regulation of DNA-templated transcription
GO:0050793	0.340	regulation of developmental process
GO:2000628	0.334	regulation of miRNA metabolic process
GO:0048731	0.302	system development
GO:0051254	0.302	positive regulation of RNA metabolic process
GO:0071495	0.300	cellular response to endogenous stimulus
GO:1902893	0.300	regulation of miRNA transcription

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

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GO term	C-score	Name
GO:0043231	1.000	intracellular membrane-bounded organelle
GO:0005737	0.999	cytoplasm
GO:0005739	0.970	mitochondrion
GO:0005634	0.951	nucleus
GO:0005576	0.418	extracellular region
GO:0043073	0.355	germ cell nucleus
GO:0001673	0.347	male germ cell nucleus

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

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[0.4,0.5)

[0.5,0.6)

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Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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