StarFunc result for job id P18124

User Input

>input (248 residues)
MEGVEEKKKEVPAVPETLKKKRRNFAELKIKRLRKKFAQKMLRKARRKLIYEKAKHYHKE
YRQMYRTEIRMARMARKAGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNG
TFVKLNKASINMLRIVEPYIAWGYPNLKSVNELIYKRGYGKINKKRIALTDNALIARSLG
KYGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPRGGMKKKTTHFVEGGDAGNREDQI
NRLIRRMN

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P14148	0.958	0.882	2.772E-44	270	0.952	0.874	P14148.pdb.gz	RL7_MOUSE Large ribosomal subunit protein uL30 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2
2	AFDB:A8WGL4	0.976	0.984	1.215E-40	246	0.778	0.785	A8WGL4.pdb.gz
3	PDB:5aj0AF	0.885	0.937	5.079E-38	234	0.944	1.000	5aj0AF.pdb.gz	Structural Snapshots of Actively Translating Human Ribosomes
4	PDB:7oyaF1	0.877	0.978	3.006E-35	222	0.730	0.815	7oyaF1.pdb.gz	A molecular network of conserved factors keeps ribosomes dormant in the egg.
5	AFDB:Q9LHP1	0.960	0.976	5.818E-35	244	0.585	0.594	Q9LHP1.pdb.gz	RL74_ARATH Large ribosomal subunit protein uL30w OS=Arabidopsis thaliana OX=3702 GN=RPL7D PE=2 SV=1
6	AFDB:F4IT48	0.946	0.950	2.961E-34	247	0.585	0.587	F4IT48.pdb.gz	F4IT48_ARATH Ribosomal protein L30/L7 family protein OS=Arabidopsis thaliana OX=3702 GN=At2g44120 PE=1 SV=1
7	AFDB:P32100	0.964	0.949	1.935E-33	252	0.560	0.552	P32100.pdb.gz	RL7_DROME Large ribosomal subunit protein uL30 OS=Drosophila melanogaster OX=7227 GN=RpL7 PE=1 SV=2
8	AFDB:P11874	0.961	0.969	2.999E-33	246	0.540	0.545	P11874.pdb.gz	RL7_DICDI Large ribosomal subunit protein uL30 OS=Dictyostelium discoideum OX=44689 GN=rpl7 PE=1 SV=3
9	AFDB:O60143	0.952	0.941	1.048E-32	251	0.536	0.530	O60143.pdb.gz	RL7C_SCHPO Large ribosomal subunit protein uL30C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl701 PE=1 SV=1
10	AFDB:P25457	0.962	0.954	3.038E-32	250	0.532	0.528	P25457.pdb.gz	RL7B_SCHPO Large ribosomal subunit protein uL30B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl702 PE=1 SV=1
11	AFDB:A0A1D8PDL6	0.926	0.953	4.707E-32	241	0.496	0.510	A0A1D8PDL6.pdb.gz	RL7A_CANAL Large ribosomal subunit protein uL30 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=RPL7A PE=1 SV=1
12	AFDB:Q6FSN6	0.938	0.953	2.250E-31	244	0.492	0.500	Q6FSN6.pdb.gz	RL7_CANGA Large ribosomal subunit protein uL30 OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=RPL7 PE=3 SV=1
13	PDB:7pzyo	0.867	0.917	1.943E-30	234	0.488	0.517	7pzyo.pdb.gz	E-site drug specificity of the human pathogen Candida albicans ribosome.
14	PDB:4v6wCF	0.761	0.823	4.279E-27	229	0.540	0.585	4v6wCF.pdb.gz	Structures of the human and Drosophila 80S ribosome.
15	PDB:6c0fF	0.936	0.959	4.555E-27	242	0.488	0.500	6c0fF.pdb.gz	Modular assembly of the nucleolar pre-60S ribosomal subunit.
16	PDB:4v8mBw	0.810	0.782	4.681E-20	257	0.440	0.424	4v8mBw.pdb.gz	High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
17	PDB:6elzt	0.551	0.474	4.811E-13	290	0.294	0.252	6elzt.pdb.gz	Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
18	PDB:4v7fr	0.582	0.454	4.937E-11	322	0.270	0.208	4v7fr.pdb.gz	60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.
19	PDB:6cb1t	0.567	0.502	5.255E-11	282	0.262	0.230	6cb1t.pdb.gz	Modular assembly of the nucleolar pre-60S ribosomal subunit.
20	PDB:7ohxt	0.431	0.523	1.396E-7	202	0.206	0.252	7ohxt.pdb.gz	Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P18124	0.0	500	248	1.000	1.000	RL7_HUMAN Large ribosomal subunit protein uL30 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1
2	P05426	2.99e-173	479	260	0.944	0.900	RL7_RAT Large ribosomal subunit protein uL30 OS=Rattus norvegicus OX=10116 GN=Rpl7 PE=1 SV=2
3	P14148	7.37e-173	478	270	0.952	0.874	RL7_MOUSE Large ribosomal subunit protein uL30 OS=Mus musculus OX=10090 GN=Rpl7 PE=1 SV=2
4	Q6Q417	8.27e-140	394	246	0.778	0.785	Q6Q417_DANRE 60S ribosomal protein L7 OS=Danio rerio OX=7955 GN=bb02h10 PE=1 SV=1
5	Q9LHP1	1.82e-103	301	244	0.585	0.594	RL74_ARATH Large ribosomal subunit protein uL30w OS=Arabidopsis thaliana OX=3702 GN=RPL7D PE=2 SV=1
6	P60040	1.26e-101	297	242	0.577	0.591	RL72_ARATH Large ribosomal subunit protein uL30y OS=Arabidopsis thaliana OX=3702 GN=RPL7B PE=1 SV=1
7	F4IT48	4.10e-101	296	247	0.577	0.579	F4IT48_ARATH Ribosomal protein L30/L7 family protein OS=Arabidopsis thaliana OX=3702 GN=At2g44120 PE=1 SV=1
8	P32100	4.27e-93	276	252	0.552	0.544	RL7_DROME Large ribosomal subunit protein uL30 OS=Drosophila melanogaster OX=7227 GN=RpL7 PE=1 SV=2
9	O60143	3.71e-92	273	251	0.536	0.530	RL7C_SCHPO Large ribosomal subunit protein uL30C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl701 PE=1 SV=1
10	P25457	5.63e-91	270	250	0.540	0.536	RL7B_SCHPO Large ribosomal subunit protein uL30B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl702 PE=1 SV=1
11	A0A1D8PDL6	3.49e-86	258	241	0.496	0.510	RL7A_CANAL Large ribosomal subunit protein uL30 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=RPL7A PE=1 SV=1
12	P11874	4.07e-85	255	246	0.556	0.561	RL7_DICDI Large ribosomal subunit protein uL30 OS=Dictyostelium discoideum OX=44689 GN=rpl7 PE=1 SV=3
13	Q6FSN6	2.75e-83	250	244	0.488	0.496	RL7_CANGA Large ribosomal subunit protein uL30 OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=RPL7 PE=3 SV=1
14	P05737	5.96e-82	247	244	0.460	0.467	RL7A_YEAST Large ribosomal subunit protein uL30A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL7A PE=1 SV=3
15	Q12213	8.63e-82	246	244	0.460	0.467	RL7B_YEAST Large ribosomal subunit protein uL30B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL7B PE=1 SV=3
16	P17937	4.17e-75	230	249	0.484	0.482	RL7A_SCHPO Large ribosomal subunit protein uL30A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rlp7 PE=1 SV=1
17	Q57V37	1.48e-71	221	242	0.423	0.434	Q57V37_TRYB2 60S ribosomal protein L7, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb07.43M14.120 PE=3 SV=1
18	Q57V35	3.36e-71	220	257	0.423	0.409	Q57V35_TRYB2 60S ribosomal protein L7, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb07.43M14.140 PE=1 SV=1
19	Q6DKI1	1.34e-64	203	255	0.431	0.420	RL7L_HUMAN Ribosomal protein uL30-like OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2
20	Q9D8M4	1.32e-63	200	246	0.431	0.435	RL7L_MOUSE Large ribosomal subunit protein uL30-like 1 OS=Mus musculus OX=10090 GN=Rpl7l1 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00327 Ribosomal_L30	1.2e-20	84.5	Ribosomal protein L30p/L7e
2	PF08079 Ribosomal_L30_N	1.5e-23	94.1	Ribosomal L30 N-terminal domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000339795

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000222247	0.999	Belongs to the eukaryotic ribosomal protein eL20 family.
2	9606.ENSP00000225430	0.999	Ribosomal protein L19
3	9606.ENSP00000230050	0.999	Ribosomal protein S12
4	9606.ENSP00000251453	0.999	Ribosomal protein S16
5	9606.ENSP00000259469	0.999	60S ribosomal protein L35
6	9606.ENSP00000262584	0.999	60S ribosomal protein L8
7	9606.ENSP00000270625	0.999	Ribosomal protein S11
8	9606.ENSP00000272317	0.999	Ubiquitin-40S ribosomal protein S27a
9	9606.ENSP00000278572	0.999	40S ribosomal protein S3
10	9606.ENSP00000296674	0.999	40S ribosomal protein S23
11	9606.ENSP00000302896	0.999	Ribosomal protein S9
12	9606.ENSP00000307889	0.999	Ribosomal protein L13
13	9606.ENSP00000307940	0.999	Elongation factor 2
14	9606.ENSP00000309334	0.999	Ribosomal protein L15
15	9606.ENSP00000309830	0.999	Ribosomal protein L38
16	9606.ENSP00000311430	0.999	L ribosomal proteins
17	9606.ENSP00000318646	0.999	Ribosomal protein S15a
18	9606.ENSP00000322419	0.999	60S acidic ribosomal protein P2
19	9606.ENSP00000339095	0.999	40S ribosomal protein S7
20	9606.ENSP00000341885	0.999	Ribosomal protein S2

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003735	1.000	structural constituent of ribosome
GO:0003723	1.000	RNA binding
GO:0005515	0.998	protein binding
GO:0003729	0.972	mRNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

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[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0071704	0.985	organic substance metabolic process
GO:0044237	0.985	cellular metabolic process
GO:0044238	0.984	primary metabolic process
GO:0034641	0.975	cellular nitrogen compound metabolic process
GO:0010467	0.967	gene expression
GO:0009058	0.825	biosynthetic process
GO:0006412	0.749	translation
GO:0065007	0.729	biological regulation
GO:0050789	0.712	regulation of biological process
GO:0050794	0.656	regulation of cellular process
GO:0046483	0.547	heterocycle metabolic process
GO:0002181	0.501	cytoplasmic translation
GO:1901360	0.417	organic cyclic compound metabolic process
GO:0006725	0.404	cellular aromatic compound metabolic process
GO:0071840	0.387	cellular component organization or biogenesis
GO:0006139	0.383	nucleobase-containing compound metabolic process
GO:0090304	0.318	nucleic acid metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	0.998	cytosol
GO:0044391	0.998	ribosomal subunit
GO:0022626	0.994	cytosolic ribosome
GO:0070013	0.989	intracellular organelle lumen
GO:0015934	0.987	large ribosomal subunit
GO:0031981	0.984	nuclear lumen
GO:0022625	0.982	cytosolic large ribosomal subunit
GO:0016020	0.841	membrane
GO:0030054	0.784	cell junction
GO:0005730	0.782	nucleolus
GO:0045202	0.669	synapse
GO:0005654	0.539	nucleoplasm
GO:0030055	0.388	cell-substrate junction
GO:0005925	0.382	focal adhesion
GO:0012505	0.371	endomembrane system

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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