StarFunc result for job id P40429

User Input

>input (203 residues)
MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRK
RMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVV
PAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQ
AEKNVEKKIDKYTEVLKTHGLLV

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P19253	0.989	0.989	3.843E-37	203	0.956	0.956	P19253.pdb.gz	RL13A_MOUSE Large ribosomal subunit protein uL13 OS=Mus musculus OX=10090 GN=Rpl13a PE=1 SV=4
2	PDB:4v6xCO	0.938	0.942	7.658E-33	202	0.995	1.000	4v6xCO.pdb.gz	Structures of the human and Drosophila 80S ribosome.
3	AFDB:Q9VNE9	0.987	0.977	1.878E-29	205	0.567	0.561	Q9VNE9.pdb.gz	RL13A_DROME Large ribosomal subunit protein uL13 OS=Drosophila melanogaster OX=7227 GN=RpL13A PE=1 SV=1
4	AFDB:G5EB54	0.892	0.896	2.930E-28	202	0.591	0.594	G5EB54.pdb.gz	G5EB54_EMENI RL16_NEUCR 60S ribosomal protein L16Ribosomal protein L16a OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=rpl16a PE=3 SV=1
5	AFDB:Q5AB87	0.946	0.960	3.580E-27	200	0.557	0.565	Q5AB87.pdb.gz	RL16A_CANAL Large ribosomal subunit protein uL13 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=RPL16A PE=1 SV=1
6	AFDB:P26784	0.898	0.916	7.007E-27	199	0.542	0.553	P26784.pdb.gz	RL16A_YEAST Large ribosomal subunit protein uL13A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL16A PE=1 SV=3
7	AFDB:O43004	0.897	0.924	2.103E-26	197	0.547	0.563	O43004.pdb.gz	RL16C_SCHPO Large ribosomal subunit protein uL13C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl1603 PE=3 SV=1
8	AFDB:F4JD96	0.938	0.920	2.684E-26	207	0.571	0.560	F4JD96.pdb.gz	F4JD96_ARATH Ribosomal protein L13 family protein OS=Arabidopsis thaliana OX=3702 GN=At3g07110 PE=1 SV=1
9	AFDB:Q6FNP2	0.892	0.905	3.427E-26	200	0.542	0.550	Q6FNP2.pdb.gz	Q6FNP2_CANGA Candida glabrata strain CBS138 chromosome J complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=RPL16A PE=3 SV=1
10	AFDB:O42848	0.863	0.888	5.937E-26	197	0.586	0.604	O42848.pdb.gz	RL16A_SCHPO Large ribosomal subunit protein uL13A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl1602 PE=1 SV=1
11	PDB:4v6wCO	0.943	0.934	7.652E-26	205	0.567	0.561	4v6wCO.pdb.gz	Structures of the human and Drosophila 80S ribosome.
12	PDB:7pzyw	0.886	0.904	1.326E-25	199	0.542	0.553	7pzyw.pdb.gz	E-site drug specificity of the human pathogen Candida albicans ribosome.
13	PDB:6qikJ	0.929	0.957	1.946E-24	197	0.532	0.548	6qikJ.pdb.gz	Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
14	AFDB:Q585J5	0.944	0.865	7.983E-23	222	0.463	0.423	Q585J5.pdb.gz	Q585J5_TRYB2 60S ribosomal protein L13a, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb04.26G5.360 PE=1 SV=1
15	PDB:4v6iBK	0.754	0.767	4.491E-18	199	0.532	0.543	4v6iBK.pdb.gz	Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
16	PDB:4v8mBO	0.824	0.836	4.451E-15	200	0.414	0.420	4v8mBO.pdb.gz	High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
17	PDB:7abzJ	0.429	0.586	1.561E-5	142	0.148	0.211	7abzJ.pdb.gz	Structures of tmRNA and SmpB as they transit through the ribosome.
18	PDB:5v7qJ	0.414	0.552	4.685E-5	146	0.153	0.212	5v7qJ.pdb.gz	Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis.
19	PDB:7a5fK3	0.396	0.450	1.688E-4	177	0.158	0.181	7a5fK3.pdb.gz	Elongational stalling activates mitoribosome-associated quality control.
20	PDB:5mrcH	0.414	0.513	3.109E-4	160	0.167	0.212	5mrcH.pdb.gz	The structure of the yeast mitochondrial ribosome.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P40429	2.35e-147	409	203	1.000	1.000	RL13A_HUMAN Large ribosomal subunit protein uL13 OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2
2	Q5RK10	2.98e-141	394	203	0.966	0.966	Q5RK10_RAT Large ribosomal subunit protein uL13 OS=Rattus norvegicus OX=10116 GN=Rpl13a PE=1 SV=1
3	P35427	1.40e-140	392	203	0.961	0.961	RL13A_RAT Large ribosomal subunit protein uL13 OS=Rattus norvegicus OX=10116 GN=Rpl13a PE=1 SV=2
4	P19253	2.20e-140	392	203	0.956	0.956	RL13A_MOUSE Large ribosomal subunit protein uL13 OS=Mus musculus OX=10090 GN=Rpl13a PE=1 SV=4
5	A0A1W2Q6L2	2.83e-136	390	444	0.946	0.432	A0A1W2Q6L2_RAT Large ribosomal subunit protein uL13 OS=Rattus norvegicus OX=10116 GN=Flt3lg PE=1 SV=2
6	Q9VNE9	1.24e-85	253	205	0.567	0.561	RL13A_DROME Large ribosomal subunit protein uL13 OS=Drosophila melanogaster OX=7227 GN=RpL13A PE=1 SV=1
7	G5EB54	2.40e-82	244	202	0.576	0.579	G5EB54_EMENI RL16_NEUCR 60S ribosomal protein L16Ribosomal protein L16a OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=rpl16a PE=3 SV=1
8	Q9SVR0	5.12e-82	244	206	0.576	0.568	R13A3_ARATH Large ribosomal subunit protein uL13x OS=Arabidopsis thaliana OX=3702 GN=RPL13AC PE=2 SV=1
9	Q9LRX8	8.75e-82	243	206	0.571	0.563	R13A2_ARATH Large ribosomal subunit protein uL13y OS=Arabidopsis thaliana OX=3702 GN=RPL13AB PE=2 SV=1
10	O42991	1.18e-80	240	197	0.562	0.579	RL16B_SCHPO Large ribosomal subunit protein uL13B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl1601 PE=1 SV=1
11	O42848	1.60e-80	240	197	0.581	0.599	RL16A_SCHPO Large ribosomal subunit protein uL13A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl1602 PE=1 SV=1
12	Q9FKC0	3.72e-80	239	206	0.567	0.558	R13A4_ARATH Large ribosomal subunit protein uL13w OS=Arabidopsis thaliana OX=3702 GN=RPL13AD PE=2 SV=1
13	F4JD96	9.64e-80	238	207	0.576	0.565	F4JD96_ARATH Ribosomal protein L13 family protein OS=Arabidopsis thaliana OX=3702 GN=At3g07110 PE=1 SV=1
14	O43004	7.34e-79	236	197	0.576	0.594	RL16C_SCHPO Large ribosomal subunit protein uL13C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl1603 PE=3 SV=1
15	Q5AB87	5.64e-77	231	200	0.517	0.525	RL16A_CANAL Large ribosomal subunit protein uL13 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=RPL16A PE=1 SV=1
16	P26784	1.24e-76	230	199	0.537	0.548	RL16A_YEAST Large ribosomal subunit protein uL13A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL16A PE=1 SV=3
17	Q6FNP2	1.58e-76	230	200	0.532	0.540	Q6FNP2_CANGA Candida glabrata strain CBS138 chromosome J complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=RPL16A PE=3 SV=1
18	P26785	8.07e-75	225	198	0.517	0.530	RL16B_YEAST Large ribosomal subunit protein uL13B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL16B PE=1 SV=3
19	Q6NVV1	2.95e-56	175	102	0.448	0.892	R13P3_HUMAN Putative ribosomal protein uL13-like OS=Homo sapiens OX=9606 GN=RPL13AP3 PE=5 SV=1
20	A0A1W2Q602	7.91e-54	170	131	0.463	0.718	A0A1W2Q602_RAT Ribosomal protein L13A OS=Rattus norvegicus OX=10116 GN=Rpl13a PE=1 SV=2

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00572 Ribosomal_L13	1.8e-20	84.6	Ribosomal protein L13
2	PF14718 SLT_L	1.7e+02	13.8	Soluble lytic murein transglycosylase L domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000375730

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000222247	0.999	Belongs to the eukaryotic ribosomal protein eL20 family.
2	9606.ENSP00000225430	0.999	Ribosomal protein L19
3	9606.ENSP00000229239	0.999	Glyceraldehyde-3-phosphate dehydrogenase
4	9606.ENSP00000230050	0.999	Ribosomal protein S12
5	9606.ENSP00000251453	0.999	Ribosomal protein S16
6	9606.ENSP00000259469	0.999	60S ribosomal protein L35
7	9606.ENSP00000262584	0.999	60S ribosomal protein L8
8	9606.ENSP00000270625	0.999	Ribosomal protein S11
9	9606.ENSP00000272317	0.999	Ubiquitin-40S ribosomal protein S27a
10	9606.ENSP00000274242	0.999	60S ribosomal protein L37
11	9606.ENSP00000278572	0.999	40S ribosomal protein S3
12	9606.ENSP00000296674	0.999	40S ribosomal protein S23
13	9606.ENSP00000302896	0.999	Ribosomal protein S9
14	9606.ENSP00000307889	0.999	Ribosomal protein L13
15	9606.ENSP00000307940	0.999	Elongation factor 2
16	9606.ENSP00000309334	0.999	Ribosomal protein L15
17	9606.ENSP00000309830	0.999	Ribosomal protein L38
18	9606.ENSP00000311430	0.999	L ribosomal proteins
19	9606.ENSP00000318646	0.999	Ribosomal protein S15a
20	9606.ENSP00000322419	0.999	60S acidic ribosomal protein P2

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003735	1.000	structural constituent of ribosome
GO:0003723	1.000	RNA binding
GO:0003729	0.972	mRNA binding
GO:0005515	0.318	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.985	cellular process
GO:0050789	0.969	regulation of biological process
GO:0050794	0.961	regulation of cellular process
GO:0050896	0.949	response to stimulus
GO:0071704	0.890	organic substance metabolic process
GO:0044237	0.884	cellular metabolic process
GO:0044238	0.882	primary metabolic process
GO:0006807	0.864	nitrogen compound metabolic process
GO:0042221	0.848	response to chemical
GO:0043170	0.841	macromolecule metabolic process
GO:0019222	0.811	regulation of metabolic process
GO:0051171	0.759	regulation of nitrogen compound metabolic process
GO:0051716	0.755	cellular response to stimulus
GO:1901564	0.714	organonitrogen compound metabolic process
GO:0060255	0.692	regulation of macromolecule metabolic process
GO:0010033	0.687	response to organic substance
GO:0010467	0.670	gene expression
GO:0034641	0.652	cellular nitrogen compound metabolic process
GO:0006412	0.625	translation
GO:0080090	0.574	regulation of primary metabolic process
GO:0031323	0.553	regulation of cellular metabolic process
GO:0070887	0.543	cellular response to chemical stimulus
GO:0002181	0.505	cytoplasmic translation
GO:0071310	0.419	cellular response to organic substance
GO:0031326	0.418	regulation of cellular biosynthetic process
GO:0010556	0.415	regulation of macromolecule biosynthetic process
GO:0048518	0.393	positive regulation of biological process
GO:0051246	0.327	regulation of protein metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	0.999	cytosol
GO:0044391	0.999	ribosomal subunit
GO:0022626	0.994	cytosolic ribosome
GO:0015934	0.994	large ribosomal subunit
GO:0022625	0.977	cytosolic large ribosomal subunit
GO:0070013	0.951	intracellular organelle lumen
GO:0043231	0.925	intracellular membrane-bounded organelle
GO:0016020	0.836	membrane
GO:0005634	0.753	nucleus
GO:0031981	0.670	nuclear lumen
GO:0030054	0.338	cell junction

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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