StarFunc result for job id P50914

User Input

>input (215 residues)
MVFRRFVEVGRVAYVSFGPHAGKLVAIVDVIDQNRALVDGPCTQVRRQAMPFKCMQLTDF
ILKFPHSAHQKYVRQAWQKADINTKWAATRWAKKIEARERKAKMTDFDRFKVMKAKKMRN
RIIKNEVKKLQKAALLKASPKKAPGTKGTAAAAAAAAAAKVPAKKITAASKKAPAQKVPA
QKATGQKAAPAPKAQKGQKAPAQKAPAPKASGKKA

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q6IPH7	0.668	0.653	9.596E-32	220	0.995	0.973	Q6IPH7.pdb.gz	Q6IPH7_HUMAN Large ribosomal subunit protein eL14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=1
2	AFDB:Q9CR57	0.682	0.676	3.931E-27	217	0.814	0.806	Q9CR57.pdb.gz	RL14_MOUSE Large ribosomal subunit protein eL14 OS=Mus musculus OX=10090 GN=Rpl14 PE=1 SV=3
3	PDB:5aj0AM	0.627	0.959	5.676E-21	139	0.647	1.000	5aj0AM.pdb.gz	Structural Snapshots of Actively Translating Human Ribosomes
4	AFDB:P55841	0.602	0.777	6.922E-15	166	0.274	0.355	P55841.pdb.gz	RL14_DROME Large ribosomal subunit protein eL14 OS=Drosophila melanogaster OX=7227 GN=RpL14 PE=1 SV=1
5	AFDB:Q9SIM4	0.601	0.950	1.452E-13	134	0.279	0.448	Q9SIM4.pdb.gz	RL141_ARATH Large ribosomal subunit protein eL14z OS=Arabidopsis thaliana OX=3702 GN=RPL14A PE=2 SV=1
6	AFDB:O94238	0.582	0.917	1.749E-13	134	0.256	0.410	O94238.pdb.gz	RL14_SCHPO Large ribosomal subunit protein eL14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl14 PE=1 SV=1
7	AFDB:Q54Z09	0.615	0.831	6.859E-13	157	0.256	0.350	Q54Z09.pdb.gz	RL14_DICDI Large ribosomal subunit protein eL14 OS=Dictyostelium discoideum OX=44689 GN=rpl14 PE=3 SV=1
8	AFDB:P36105	0.559	0.855	7.766E-13	138	0.260	0.406	P36105.pdb.gz	RL14A_YEAST Large ribosomal subunit protein eL14A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL14A PE=1 SV=1
9	AFDB:Q6FJ02	0.575	0.887	1.059E-12	137	0.251	0.394	Q6FJ02.pdb.gz	Q6FJ02_CANGA Candida glabrata strain CBS138 chromosome M complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=CAGL0M10241g PE=3 SV=1
10	PDB:4v6wCM	0.549	0.733	2.913E-11	159	0.265	0.358	4v6wCM.pdb.gz	Structures of the human and Drosophila 80S ribosome.
11	AFDB:Q383F5	0.560	0.631	4.380E-10	189	0.205	0.233	Q383F5.pdb.gz	Q383F5_TRYB2 40S ribosomal protein L14, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.3020 PE=3 SV=1
12	PDB:7pzyu	0.546	0.884	5.396E-10	130	0.247	0.408	7pzyu.pdb.gz	E-site drug specificity of the human pathogen Candida albicans ribosome.
13	PDB:4v6iBN	0.475	0.685	1.204E-8	138	0.260	0.406	4v6iBN.pdb.gz	Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution.
14	PDB:5apnZ	0.257	0.381	1.818E-3	135	0.112	0.178	5apnZ.pdb.gz	Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
15	PDB:4v6xCE	0.271	0.225	2.480E-3	262	0.070	0.057	4v6xCE.pdb.gz	Structures of the human and Drosophila 80S ribosome.
16	AFDB:P38753	0.173	0.090	4.241E-3	452	0.140	0.066	P38753.pdb.gz	HSE1_YEAST Class E vacuolar protein-sorting machinery protein HSE1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HSE1 PE=1 SV=1
17	PDB:7cpuLZ	0.257	0.393	6.295E-3	135	0.098	0.156	7cpuLZ.pdb.gz	A male germ-cell-specific ribosome controls male fertility.
18	PDB:4v6wCZ	0.240	0.372	9.724E-3	134	0.079	0.127	4v6wCZ.pdb.gz	Structures of the human and Drosophila 80S ribosome.
19	PDB:7pzyn	0.253	0.347	9.724E-3	155	0.088	0.123	7pzyn.pdb.gz	E-site drug specificity of the human pathogen Candida albicans ribosome.
20	PDB:4v8mBv	0.258	0.348	1.035E-2	157	0.047	0.064	4v8mBv.pdb.gz	High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P50914	1.85e-151	421	215	1.000	1.000	RL14_HUMAN Large ribosomal subunit protein eL14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4
2	Q6IPH7	2.89e-149	415	220	1.000	0.977	Q6IPH7_HUMAN Large ribosomal subunit protein eL14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=1
3	A8K3Q9	5.17e-148	412	216	0.995	0.991	A8K3Q9_HUMAN Large ribosomal subunit protein eL14 OS=Homo sapiens OX=9606 PE=1 SV=1
4	A1XQU3	6.19e-108	310	213	0.888	0.897	RL14_PIG Large ribosomal subunit protein eL14 OS=Sus scrofa OX=9823 GN=RPL14 PE=1 SV=1
5	Q9CR57	1.89e-95	279	217	0.828	0.820	RL14_MOUSE Large ribosomal subunit protein eL14 OS=Mus musculus OX=10090 GN=Rpl14 PE=1 SV=3
6	Q63507	5.52e-93	273	214	0.595	0.598	RL14_RAT Large ribosomal subunit protein eL14 OS=Rattus norvegicus OX=10116 GN=Rpl14 PE=1 SV=3
7	P55841	1.11e-35	125	166	0.288	0.373	RL14_DROME Large ribosomal subunit protein eL14 OS=Drosophila melanogaster OX=7227 GN=RpL14 PE=1 SV=1
8	Q9SIM4	2.80e-35	123	134	0.279	0.448	RL141_ARATH Large ribosomal subunit protein eL14z OS=Arabidopsis thaliana OX=3702 GN=RPL14A PE=2 SV=1
9	Q9T043	5.67e-35	122	134	0.274	0.440	RL142_ARATH Large ribosomal subunit protein eL14y OS=Arabidopsis thaliana OX=3702 GN=RPL14B PE=1 SV=1
10	O94238	8.19e-35	122	134	0.260	0.418	RL14_SCHPO Large ribosomal subunit protein eL14 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rpl14 PE=1 SV=1
11	P38754	7.33e-30	109	138	0.260	0.406	RL14B_YEAST Large ribosomal subunit protein eL14B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL14B PE=1 SV=1
12	P36105	1.19e-29	109	138	0.260	0.406	RL14A_YEAST Large ribosomal subunit protein eL14A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPL14A PE=1 SV=1
13	Q6FJ02	2.51e-29	108	137	0.247	0.387	Q6FJ02_CANGA Candida glabrata strain CBS138 chromosome M complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=CAGL0M10241g PE=3 SV=1
14	Q54Z09	1.15e-26	102	157	0.279	0.382	RL14_DICDI Large ribosomal subunit protein eL14 OS=Dictyostelium discoideum OX=44689 GN=rpl14 PE=3 SV=1
15	A0A1D8PFL9	3.41e-25	97.4	131	0.237	0.389	RL14_CANAL Large ribosomal subunit protein eL14 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=RPL14 PE=1 SV=1
16	Q583T1	2.01e-13	68.2	189	0.172	0.196	Q583T1_TRYB2 40S ribosomal protein L14, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb06.3D8.630 PE=3 SV=1
17	Q383F5	2.54e-13	67.8	189	0.172	0.196	Q383F5_TRYB2 40S ribosomal protein L14, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.3020 PE=3 SV=1
18	O88737	0.15	35.4	3942	0.121	0.007	BSN_MOUSE Protein bassoon OS=Mus musculus OX=10090 GN=Bsn PE=1 SV=4
19	Q6FQ10	0.23	34.7	1618	0.121	0.016	Q6FQ10_CANGA Candida glabrata strain CBS138 chromosome I complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=CAGL0I10098g PE=4 SV=1
20	Q38BJ2	0.24	34.7	1183	0.153	0.028	Q38BJ2_TRYB2 3-hydroxyacyl-CoA dehydrogenase C-terminal domain-containing protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.70.3190 PE=4 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00467 KOW	4.2	18.7	KOW motif
2	PF01929 Ribosomal_L14e	1.9e-26	103.7	Ribosomal protein L14

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000379506

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000222247	0.999	Belongs to the eukaryotic ribosomal protein eL20 family.
2	9606.ENSP00000225430	0.999	Ribosomal protein L19
3	9606.ENSP00000230050	0.999	Ribosomal protein S12
4	9606.ENSP00000251453	0.999	Ribosomal protein S16
5	9606.ENSP00000259469	0.999	60S ribosomal protein L35
6	9606.ENSP00000262584	0.999	60S ribosomal protein L8
7	9606.ENSP00000270625	0.999	Ribosomal protein S11
8	9606.ENSP00000272317	0.999	Ubiquitin-40S ribosomal protein S27a
9	9606.ENSP00000274242	0.999	60S ribosomal protein L37
10	9606.ENSP00000278572	0.999	40S ribosomal protein S3
11	9606.ENSP00000296674	0.999	40S ribosomal protein S23
12	9606.ENSP00000302896	0.999	Ribosomal protein S9
13	9606.ENSP00000307889	0.999	Ribosomal protein L13
14	9606.ENSP00000309334	0.999	Ribosomal protein L15
15	9606.ENSP00000309830	0.999	Ribosomal protein L38
16	9606.ENSP00000311430	0.999	L ribosomal proteins
17	9606.ENSP00000318646	0.999	Ribosomal protein S15a
18	9606.ENSP00000322419	0.999	60S acidic ribosomal protein P2
19	9606.ENSP00000339095	0.999	40S ribosomal protein S7
20	9606.ENSP00000339795	0.999	60S ribosomal protein L7

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0003735	0.986	structural constituent of ribosome
GO:0003723	0.986	RNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0044238	0.997	primary metabolic process
GO:0044237	0.997	cellular metabolic process
GO:0006807	0.995	nitrogen compound metabolic process
GO:0043170	0.995	macromolecule metabolic process
GO:0044260	0.991	cellular macromolecule metabolic process
GO:0009059	0.991	macromolecule biosynthetic process
GO:0019538	0.991	protein metabolic process
GO:0006518	0.987	peptide metabolic process
GO:0002181	0.983	cytoplasmic translation
GO:0090304	0.978	nucleic acid metabolic process
GO:0071840	0.972	cellular component organization or biogenesis
GO:0042254	0.938	ribosome biogenesis
GO:0006364	0.926	rRNA processing
GO:0042273	0.776	ribosomal large subunit biogenesis

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0015934	1.000	large ribosomal subunit
GO:0022626	0.998	cytosolic ribosome
GO:0016020	0.983	membrane
GO:0022625	0.975	cytosolic large ribosomal subunit
GO:0043227	0.962	membrane-bounded organelle
GO:0043231	0.904	intracellular membrane-bounded organelle
GO:0005576	0.900	extracellular region
GO:0065010	0.836	extracellular membrane-bounded organelle
GO:1903561	0.825	extracellular vesicle
GO:0070062	0.801	extracellular exosome
GO:0070013	0.789	intracellular organelle lumen
GO:0030054	0.655	cell junction
GO:0005634	0.598	nucleus
GO:0031981	0.576	nuclear lumen
GO:0045202	0.428	synapse
GO:0012505	0.414	endomembrane system

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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