StarFunc result for job id P62280

User Input

>input (158 residues)
MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRYYKNIGLGFKTPKEAIEGTYIDKKC
PFTGNVSIRGRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFRDV
QIGDIVTVGECRPLSKTVRFNVLKVTKAAGTKKQFQKF

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P62280	1.000	1.000	4.714E-30	158	1.000	1.000	P62280.pdb.gz	RS11_HUMAN Small ribosomal subunit protein uS17 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3
2	PDB:6fecG	0.813	0.813	8.824E-22	158	1.000	1.000	6fecG.pdb.gz	Structure of a human cap-dependent 48S translation pre-initiation complex.
3	AFDB:Q20206	0.904	0.921	1.030E-21	155	0.646	0.658	Q20206.pdb.gz	Q20206_CAEEL Small ribosomal subunit protein uS17 OS=Caenorhabditis elegans OX=6239 GN=rps-11 PE=1 SV=1
4	AFDB:P0CX47	0.890	0.901	1.533E-21	156	0.684	0.692	P0CX47.pdb.gz	RS11A_YEAST Small ribosomal subunit protein uS17A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS11A PE=1 SV=1
5	AFDB:Q0E9B6	0.889	0.906	2.282E-21	155	0.677	0.690	Q0E9B6.pdb.gz	RS11_DROME Small ribosomal subunit protein uS17 OS=Drosophila melanogaster OX=7227 GN=RpS11 PE=1 SV=1
6	AFDB:P0CT73	0.830	0.862	1.977E-20	152	0.627	0.651	P0CT73.pdb.gz	RS11A_SCHPO Small ribosomal subunit protein uS17A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps1101 PE=2 SV=1
7	PDB:5datC1	0.827	0.842	3.249E-19	155	0.684	0.697	5datC1.pdb.gz	Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
8	AFDB:P16181	0.844	0.834	5.974E-19	160	0.601	0.594	P16181.pdb.gz	RS111_ARATH Small ribosomal subunit protein uS17z OS=Arabidopsis thaliana OX=3702 GN=RPS11A PE=2 SV=1
9	AFDB:Q38CI4	0.834	0.759	5.974E-19	174	0.551	0.500	Q38CI4.pdb.gz	Q38CI4_TRYB2 40S ribosomal proteins S11, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.70.7695 PE=1 SV=1
10	PDB:4v6wAL	0.841	0.857	5.714E-17	155	0.696	0.710	4v6wAL.pdb.gz	Structures of the human and Drosophila 80S ribosome.
11	PDB:4v8mAE	0.797	0.788	6.575E-16	160	0.557	0.550	4v8mAE.pdb.gz	High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
12	AFDB:C3SQY7	0.465	0.847	1.263E-7	84	0.177	0.333	C3SQY7.pdb.gz	C3SQY7_ECOLX Small ribosomal subunit protein uS17 OS=Escherichia coli OX=562 GN=rpsQ PE=1 SV=1
13	AFDB:P9WH51	0.452	0.523	3.933E-7	135	0.215	0.252	P9WH51.pdb.gz	RS17_MYCTU Small ribosomal subunit protein uS17 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=rpsQ PE=1 SV=1
14	PDB:3j9zSQ	0.463	0.840	3.995E-7	83	0.177	0.337	3j9zSQ.pdb.gz	Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
15	PDB:5mrcQQ	0.439	0.347	7.463E-7	204	0.139	0.108	5mrcQQ.pdb.gz	The structure of the yeast mitochondrial ribosome.
16	AFDB:Q03246	0.455	0.309	8.232E-7	237	0.133	0.089	Q03246.pdb.gz	RT17_YEAST Small ribosomal subunit protein uS17m OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MRPS17 PE=1 SV=1
17	PDB:7mscq	0.464	0.746	7.665E-6	95	0.158	0.263	7mscq.pdb.gz	Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis.
18	PDB:7p2eN	0.435	0.609	9.090E-6	110	0.120	0.173	7p2eN.pdb.gz	Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules.
19	PDB:7pntN	0.432	0.595	1.353E-5	113	0.101	0.142	7pntN.pdb.gz	Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
20	PDB:7pubCQ	0.438	0.313	6.273E-5	226	0.127	0.088	7pubCQ.pdb.gz	Mitoribosomal small subunit maturation involves formation of initiation-like complexes.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P62280	1.41e-115	325	158	1.000	1.000	RS11_HUMAN Small ribosomal subunit protein uS17 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3
2	P62281	1.41e-115	325	158	1.000	1.000	RS11_MOUSE Small ribosomal subunit protein uS17 OS=Mus musculus OX=10090 GN=Rps11 PE=1 SV=3
3	P62282	1.41e-115	325	158	1.000	1.000	RS11_RAT Small ribosomal subunit protein uS17 OS=Rattus norvegicus OX=10116 GN=Rps11 PE=1 SV=3
4	Q0E9B6	6.17e-75	222	155	0.715	0.729	RS11_DROME Small ribosomal subunit protein uS17 OS=Drosophila melanogaster OX=7227 GN=RpS11 PE=1 SV=1
5	Q20206	5.05e-73	218	155	0.652	0.665	Q20206_CAEEL Small ribosomal subunit protein uS17 OS=Caenorhabditis elegans OX=6239 GN=rps-11 PE=1 SV=1
6	P0CX47	1.07e-71	214	156	0.690	0.699	RS11A_YEAST Small ribosomal subunit protein uS17A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS11A PE=1 SV=1
7	P0CX48	1.07e-71	214	156	0.690	0.699	RS11B_YEAST Small ribosomal subunit protein uS17B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS11B PE=1 SV=1
8	P0CT73	1.92e-67	203	152	0.627	0.651	RS11A_SCHPO Small ribosomal subunit protein uS17A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps1101 PE=2 SV=1
9	O65569	9.52e-65	197	159	0.608	0.604	RS112_ARATH Small ribosomal subunit protein uS17y OS=Arabidopsis thaliana OX=3702 GN=RPS11B PE=2 SV=2
10	P16181	3.85e-63	192	160	0.595	0.588	RS111_ARATH Small ribosomal subunit protein uS17z OS=Arabidopsis thaliana OX=3702 GN=RPS11A PE=2 SV=1
11	P42733	2.92e-62	190	159	0.576	0.572	RS113_ARATH Small ribosomal subunit protein uS17x OS=Arabidopsis thaliana OX=3702 GN=RPS11C PE=2 SV=2
12	Q4GYQ5	1.57e-59	184	174	0.557	0.506	Q4GYQ5_TRYB2 40S ribosomal protein S11, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=TB927.1.3180 PE=3 SV=1
13	Q38CI4	2.30e-59	184	174	0.557	0.506	Q38CI4_TRYB2 40S ribosomal proteins S11, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb10.70.7695 PE=1 SV=1
14	C3SQY7	2.51e-06	45.4	84	0.203	0.381	C3SQY7_ECOLX Small ribosomal subunit protein uS17 OS=Escherichia coli OX=562 GN=rpsQ PE=1 SV=1
15	P0AG63	2.51e-06	45.4	84	0.203	0.381	RS17_ECOLI Small ribosomal subunit protein uS17 OS=Escherichia coli (strain K12) OX=83333 GN=rpsQ PE=1 SV=2
16	Q9UUB0	0.057	33.9	90	0.082	0.144	RT17_SCHPO Small ribosomal subunit protein uS17m OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mrps17 PE=3 SV=1
17	P9WH51	0.12	33.5	135	0.171	0.200	RS17_MYCTU Small ribosomal subunit protein uS17 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=rpsQ PE=1 SV=1
18	Q03246	2.9	30.0	237	0.152	0.101	RT17_YEAST Small ribosomal subunit protein uS17m OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MRPS17 PE=1 SV=1
19	Q38DP8	7.5	28.9	307	0.127	0.065	Q38DP8_TRYB2 30S Ribosomal protein S17, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb09.211.2580 PE=1 SV=1
20	Q8TGA1	8.5	29.3	1888	0.101	0.008	AFLB_ASPPU Fatty acid synthase beta subunit aflB OS=Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) OX=1403190 GN=aflB PE=2 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF06875 PRF	3.5e+02	12.0	Plethodontid receptivity factor PRF
2	PF00366 Ribosomal_S17	1.3e-25	100.5	Ribosomal protein S17
3	PF16205 Ribosomal_S17_N	9.9e-31	117.3	Ribosomal_S17 N-terminal

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 1026970.XP_008843289.1

Rank	PPI partner	STRING score	Description
1	1026970.XP_008820326.1	0.999	40S ribosomal protein S12
2	1026970.XP_008820997.1	0.999	Ribosomal protein S5
3	1026970.XP_008821230.1	0.999	Ribosomal protein S27a
4	1026970.XP_008822798.1	0.999	60S ribosomal protein L18a isoform X1
5	1026970.XP_008823268.1	0.999	Ribosomal protein L12
6	1026970.XP_008823295.1	0.999	60S ribosomal protein L21
7	1026970.XP_008824172.1	0.999	40S ribosomal protein S25
8	1026970.XP_008825153.1	0.999	40S ribosomal protein S15a
9	1026970.XP_008825977.1	0.999	Ribosomal protein S9
10	1026970.XP_008826880.1	0.999	60S ribosomal protein L17
11	1026970.XP_008826905.1	0.999	60S ribosomal protein L23a
12	1026970.XP_008828092.1	0.999	Ribosomal protein S29
13	1026970.XP_008829698.1	0.999	60S ribosomal protein L38
14	1026970.XP_008831299.1	0.999	40S ribosomal protein S20
15	1026970.XP_008831459.1	0.999	60S ribosomal protein L9
16	1026970.XP_008832600.1	0.999	Ribosomal protein L8
17	1026970.XP_008833573.1	0.999	60S ribosomal protein L27
18	1026970.XP_008834569.1	0.999	60S ribosomal protein L4
19	1026970.XP_008835382.1	0.999	40S ribosomal protein S15
20	1026970.XP_008835642.1	0.999	40S ribosomal protein S17

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003735	1.000	structural constituent of ribosome
GO:0003723	0.999	RNA binding
GO:0005515	0.989	protein binding
GO:0003729	0.333	mRNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.992	cellular process
GO:0071704	0.987	organic substance metabolic process
GO:0006807	0.980	nitrogen compound metabolic process
GO:0043170	0.966	macromolecule metabolic process
GO:0044238	0.963	primary metabolic process
GO:0044237	0.963	cellular metabolic process
GO:0034641	0.936	cellular nitrogen compound metabolic process
GO:0006412	0.932	translation
GO:0032501	0.563	multicellular organismal process
GO:0002181	0.432	cytoplasmic translation

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0044391	0.997	ribosomal subunit
GO:0022626	0.997	cytosolic ribosome
GO:0015935	0.985	small ribosomal subunit
GO:0022627	0.983	cytosolic small ribosomal subunit
GO:0043231	0.975	intracellular membrane-bounded organelle
GO:0016020	0.970	membrane
GO:0070013	0.912	intracellular organelle lumen
GO:0005634	0.871	nucleus
GO:0031981	0.863	nuclear lumen
GO:0030054	0.714	cell junction
GO:0005654	0.306	nucleoplasm

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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