StarFunc result for job id P62701

User Input

>input (263 residues)
MARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNRLKYALTGDE
VKKICMQRFIKIDGKVRTDITYPAGFMDVISIDKTGENFRLIYDTKGRFAVHRITPEEAK
YKLCKVRKIFVGTKGIPHLVTHDARTIRYPDPLIKVNDTIQIDLETGKITDFIKFDTGNL
CMVTGGANLGRIGVITNRERHPGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPR
GKGIRLTIAEERDKRLAAKQSSG

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P22090	1.000	1.000	5.905E-52	263	0.928	0.928	P22090.pdb.gz	RS4Y1_HUMAN Small ribosomal subunit protein eS4, Y isoform 1 OS=Homo sapiens OX=9606 GN=RPS4Y1 PE=1 SV=2
2	AFDB:Q642H9	0.999	0.999	3.466E-51	263	0.932	0.932	Q642H9.pdb.gz	RS4X_DANRE Small ribosomal subunit protein eS4 OS=Danio rerio OX=7955 GN=rps4x PE=1 SV=3
3	AFDB:Q3V1Z5	0.992	0.996	1.821E-50	262	0.928	0.931	Q3V1Z5.pdb.gz	Q3V1Z5_MOUSE 40S ribosomal protein S4 OS=Mus musculus OX=10090 GN=Rps4l PE=2 SV=1
4	AFDB:P41042	0.982	0.990	1.615E-45	261	0.749	0.755	P41042.pdb.gz	RS4_DROME Small ribosomal subunit protein eS4 OS=Drosophila melanogaster OX=7227 GN=RpS4 PE=1 SV=2
5	AFDB:C8VAM4	0.984	0.991	7.597E-45	261	0.707	0.713	C8VAM4.pdb.gz	C8VAM4_EMENI 40S ribosomal protein S4 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=ANIA_04794 PE=3 SV=1
6	AFDB:P46299	0.988	0.992	2.056E-44	262	0.692	0.695	P46299.pdb.gz	RS4_GOSHI Small ribosomal subunit protein eS4 OS=Gossypium hirsutum OX=3635 GN=RPS4 PE=2 SV=1
7	AFDB:P87158	0.985	0.989	2.056E-44	262	0.707	0.710	P87158.pdb.gz	RS4A_SCHPO Small ribosomal subunit protein eS4A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps401 PE=2 SV=2
8	AFDB:P0CX35	0.985	0.993	3.028E-44	261	0.715	0.720	P0CX35.pdb.gz	RS4A_YEAST Small ribosomal subunit protein eS4A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS4A PE=1 SV=1
9	AFDB:P51405	0.983	0.969	2.476E-43	267	0.650	0.640	P51405.pdb.gz	RS4_DICDI Small ribosomal subunit protein eS4 OS=Dictyostelium discoideum OX=44689 GN=rps4 PE=1 SV=3
10	PDB:6fecI	0.952	0.952	5.270E-41	263	0.985	0.985	6fecI.pdb.gz	Structure of a human cap-dependent 48S translation pre-initiation complex.
11	PDB:4v6wAE	0.960	0.967	4.649E-39	261	0.745	0.751	4v6wAE.pdb.gz	Structures of the human and Drosophila 80S ribosome.
12	PDB:5datS4	0.965	0.976	1.958E-38	260	0.711	0.719	5datS4.pdb.gz	Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
13	AFDB:Q386F2	0.975	0.940	1.832E-36	273	0.529	0.509	Q386F2.pdb.gz	Q386F2_TRYB2 40S ribosomal protein S4 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.02.1085 PE=1 SV=1
14	PDB:4v8mA1	0.870	0.924	2.545E-25	247	0.502	0.534	4v8mA1.pdb.gz	High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
15	PDB:6tedZ	0.180	0.097	9.422E-4	510	0.072	0.037	6tedZ.pdb.gz	Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
16	PDB:4v6wCA	0.192	0.198	8.607E-3	253	0.068	0.071	4v6wCA.pdb.gz	Structures of the human and Drosophila 80S ribosome.
17	PDB:7okyZ	0.172	0.122	1.074E-2	374	0.061	0.043	7okyZ.pdb.gz	Allosteric transcription stimulation by RNA polymerase II super elongation complex.
18	PDB:4v6xCA	0.202	0.207	1.340E-2	255	0.122	0.125	4v6xCA.pdb.gz	Structures of the human and Drosophila 80S ribosome.
19	PDB:4fhnD	0.134	0.051	2.204E-2	977	0.095	0.026	4fhnD.pdb.gz
20	PDB:7pzy9	0.157	0.297	2.204E-2	126	0.042	0.087	7pzy9.pdb.gz	E-site drug specificity of the human pathogen Candida albicans ribosome.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P22090	0.0	508	263	0.928	0.928	RS4Y1_HUMAN Small ribosomal subunit protein eS4, Y isoform 1 OS=Homo sapiens OX=9606 GN=RPS4Y1 PE=1 SV=2
2	P62701	0.0	537	263	1.000	1.000	RS4X_HUMAN Small ribosomal subunit protein eS4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2
3	P62702	0.0	537	263	1.000	1.000	RS4X_MOUSE Small ribosomal subunit protein eS4 OS=Mus musculus OX=10090 GN=Rps4x PE=1 SV=2
4	P62703	0.0	537	263	1.000	1.000	RS4X_RAT Small ribosomal subunit protein eS4 OS=Rattus norvegicus OX=10116 GN=Rps4x PE=1 SV=2
5	Q3V1Z5	0.0	511	262	0.928	0.931	Q3V1Z5_MOUSE 40S ribosomal protein S4 OS=Mus musculus OX=10090 GN=Rps4l PE=2 SV=1
6	Q642H9	0.0	510	263	0.932	0.932	RS4X_DANRE Small ribosomal subunit protein eS4 OS=Danio rerio OX=7955 GN=rps4x PE=1 SV=3
7	P41042	1.51e-155	435	261	0.749	0.755	RS4_DROME Small ribosomal subunit protein eS4 OS=Drosophila melanogaster OX=7227 GN=RpS4 PE=1 SV=2
8	C8VAM4	5.78e-143	403	261	0.707	0.713	C8VAM4_EMENI 40S ribosomal protein S4 OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=ANIA_04794 PE=3 SV=1
9	P0CX35	5.97e-143	403	261	0.715	0.720	RS4A_YEAST Small ribosomal subunit protein eS4A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS4A PE=1 SV=1
10	P0CX36	5.97e-143	403	261	0.715	0.720	RS4B_YEAST Small ribosomal subunit protein eS4B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=RPS4B PE=1 SV=1
11	Q9P4W9	1.01e-142	402	262	0.711	0.714	RS4C_SCHPO Small ribosomal subunit protein eS4C OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps403 PE=1 SV=1
12	P87158	3.38e-142	401	262	0.707	0.710	RS4A_SCHPO Small ribosomal subunit protein eS4A OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps401 PE=2 SV=2
13	Q9USW5	4.16e-142	401	262	0.703	0.706	RS4B_SCHPO Small ribosomal subunit protein eS4B OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=rps402 PE=1 SV=1
14	Q8VYK6	8.91e-139	392	262	0.696	0.698	RS43_ARATH Small ribosomal subunit protein eS4x OS=Arabidopsis thaliana OX=3702 GN=RPS4D PE=2 SV=2
15	P49204	1.24e-138	392	262	0.696	0.698	RS42_ARATH Small ribosomal subunit protein eS4y OS=Arabidopsis thaliana OX=3702 GN=RPS4B PE=2 SV=4
16	Q93VH9	2.16e-138	391	261	0.696	0.701	RS41_ARATH Small ribosomal subunit protein eS4z OS=Arabidopsis thaliana OX=3702 GN=RPS4A PE=2 SV=1
17	P46299	1.75e-136	387	262	0.692	0.695	RS4_GOSHI Small ribosomal subunit protein eS4 OS=Gossypium hirsutum OX=3635 GN=RPS4 PE=2 SV=1
18	P51405	2.79e-131	374	267	0.650	0.640	RS4_DICDI Small ribosomal subunit protein eS4 OS=Dictyostelium discoideum OX=44689 GN=rps4 PE=1 SV=3
19	Q386F2	1.55e-97	288	273	0.529	0.509	Q386F2_TRYB2 40S ribosomal protein S4 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.02.1085 PE=1 SV=1
20	P25858	3.9	31.2	338	0.084	0.065	G3PC1_ARATH Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic OS=Arabidopsis thaliana OX=3702 GN=GAPC1 PE=1 SV=2

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF16121 40S_S4_C	1.2e-25	100.2	40S ribosomal protein S4 C-terminus
2	PF00467 KOW	0.018	26.2	KOW motif
3	PF00900 Ribosomal_S4e	6.8e-35	130.1	Ribosomal family S4e
4	PF08071 RS4NT	7.7e-18	75.6	RS4NT (NUC023) domain
5	PF01479 S4	0.015	26.3	S4 domain
6	PF07861 WND	3.1e+02	12.2	WisP family N-Terminal Region

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 1026970.XP_008853778.1

Rank	PPI partner	STRING score	Description
1	1026970.XP_008825153.1	0.998	40S ribosomal protein S15a
2	1026970.XP_008843289.1	0.998	40S ribosomal protein S11
3	1026970.XP_008852184.1	0.998	40S ribosomal protein S16
4	1026970.XP_008854454.1	0.998	Ribosomal protein S2
5	1026970.XP_008820326.1	0.997	40S ribosomal protein S12
6	1026970.XP_008820997.1	0.997	Ribosomal protein S5
7	1026970.XP_008824172.1	0.997	40S ribosomal protein S25
8	1026970.XP_008831299.1	0.997	40S ribosomal protein S20
9	1026970.XP_008838402.1	0.997	40S ribosomal protein S18
10	1026970.XP_008843755.1	0.997	Ribosomal protein S6
11	1026970.XP_008844671.1	0.997	Ribosomal protein S19
12	1026970.XP_008848384.1	0.997	Ribosomal protein S7
13	1026970.XP_008851519.1	0.997	40S ribosomal protein S23
14	1026970.XP_008851757.1	0.997	Ribosomal protein S13
15	1026970.XP_008852472.1	0.997	40S ribosomal protein S3a
16	1026970.XP_008820379.1	0.996	Ubiquitin-like protein fubi and ribosomal protein S30
17	1026970.XP_008821135.1	0.996	Uncharacterized protein LOC103725606
18	1026970.XP_008825977.1	0.996	Ribosomal protein S9
19	1026970.XP_008835382.1	0.996	40S ribosomal protein S15
20	1026970.XP_008835642.1	0.996	40S ribosomal protein S17

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003735	1.000	structural constituent of ribosome
GO:0003723	1.000	RNA binding
GO:0005515	0.743	protein binding
GO:0003729	0.434	mRNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0071704	0.996	organic substance metabolic process
GO:0044238	0.995	primary metabolic process
GO:0044237	0.995	cellular metabolic process
GO:0010467	0.988	gene expression
GO:0034641	0.986	cellular nitrogen compound metabolic process
GO:1901564	0.985	organonitrogen compound metabolic process
GO:0043603	0.984	amide metabolic process
GO:0044260	0.984	cellular macromolecule metabolic process
GO:1901576	0.981	organic substance biosynthetic process
GO:0044249	0.975	cellular biosynthetic process
GO:0044271	0.974	cellular nitrogen compound biosynthetic process
GO:0006412	0.945	translation
GO:0065007	0.870	biological regulation
GO:0050789	0.845	regulation of biological process
GO:0019222	0.839	regulation of metabolic process
GO:0050896	0.738	response to stimulus
GO:0050794	0.712	regulation of cellular process
GO:0060255	0.695	regulation of macromolecule metabolic process
GO:0042221	0.631	response to chemical
GO:0010468	0.619	regulation of gene expression
GO:0097305	0.613	response to alcohol
GO:0045471	0.539	response to ethanol
GO:0031323	0.477	regulation of cellular metabolic process
GO:0051171	0.475	regulation of nitrogen compound metabolic process
GO:2000112	0.474	regulation of cellular macromolecule biosynthetic process
GO:0080090	0.472	regulation of primary metabolic process
GO:0051246	0.378	regulation of protein metabolic process
GO:0002181	0.372	cytoplasmic translation
GO:0034248	0.346	regulation of amide metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	1.000	cytosol
GO:0005840	0.999	ribosome
GO:0043231	0.998	intracellular membrane-bounded organelle
GO:1990904	0.996	ribonucleoprotein complex
GO:0070013	0.993	intracellular organelle lumen
GO:0044391	0.992	ribosomal subunit
GO:0022626	0.990	cytosolic ribosome
GO:0015935	0.967	small ribosomal subunit
GO:0031981	0.965	nuclear lumen
GO:0022627	0.946	cytosolic small ribosomal subunit
GO:0016020	0.879	membrane
GO:0005654	0.391	nucleoplasm
GO:0012505	0.340	endomembrane system
GO:0030054	0.334	cell junction

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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