StarFunc result for job id P78383

User Input

>input (322 residues)
MASSSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQC
VINAVFAKILIQFFDTARVDRTRSWLYAACSISYLGAMVSSNSALQFVNYPTQVLGKSCK
PIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGIEEHTVGYGELLLLLSL
TLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMGILFTGELWEFLSFAERYPAII
YNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGT
VLVFLGLGLDAKFGKGAKKTSH

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:P78383	1.000	1.000	2.258E-42	322	1.000	1.000	P78383.pdb.gz	S35B1_HUMAN Solute carrier family 35 member B1 OS=Homo sapiens OX=9606 GN=SLC35B1 PE=1 SV=1
2	AFDB:Q9VDD7	0.933	0.890	1.332E-24	338	0.491	0.467	Q9VDD7.pdb.gz	S35B1_DROME Solute carrier family 35 member B1 homolog OS=Drosophila melanogaster OX=7227 GN=meigo PE=2 SV=1
3	AFDB:Q9BHL2	0.802	0.765	2.724E-20	340	0.435	0.412	Q9BHL2.pdb.gz	Q9BHL2_CAEEL UAA transporter OS=Caenorhabditis elegans OX=6239 GN=hut-1 PE=1 SV=1
4	AFDB:Q9M9S6	0.875	0.852	1.284E-17	331	0.332	0.323	Q9M9S6.pdb.gz	UTR3_ARATH UDP-galactose/UDP-glucose transporter 3 OS=Arabidopsis thaliana OX=3702 GN=UTR3 PE=1 SV=1
5	AFDB:O64503	0.858	0.833	2.925E-17	332	0.307	0.298	O64503.pdb.gz	UTR1_ARATH UDP-galactose/UDP-glucose transporter 1 OS=Arabidopsis thaliana OX=3702 GN=UTR1 PE=1 SV=1
6	AFDB:Q9VEI3	0.841	0.593	3.633E-17	465	0.301	0.209	Q9VEI3.pdb.gz	S35B2_DROME Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Drosophila melanogaster OX=7227 GN=sll PE=1 SV=1
7	AFDB:Q6P101	0.853	0.639	1.392E-16	435	0.314	0.232	Q6P101.pdb.gz	Q6P101_DANRE Adenosine 3'-phospho 5'-phosphosulfate transporter 1 precursor OS=Danio rerio OX=7955 GN=papst1 PE=1 SV=1
8	AFDB:Q8TB61	0.838	0.632	1.326E-15	432	0.307	0.229	Q8TB61.pdb.gz	S35B2_HUMAN Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1
9	AFDB:Q9H1N7	0.829	0.673	6.315E-15	401	0.280	0.224	Q9H1N7.pdb.gz	S35B3_HUMAN Adenosine 3'-phospho 5'-phosphosulfate transporter 2 OS=Homo sapiens OX=9606 GN=SLC35B3 PE=1 SV=1
10	AFDB:Q8MXJ9	0.823	0.635	2.126E-14	425	0.230	0.174	Q8MXJ9.pdb.gz	S35B2_CAEEL Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Caenorhabditis elegans OX=6239 GN=pst-1 PE=3 SV=4
11	PDB:5ogeG	0.726	0.760	3.085E-8	306	0.130	0.137	5ogeG.pdb.gz
12	PDB:6xboA	0.611	0.616	1.602E-7	319	0.152	0.154	6xboA.pdb.gz	Inhibition of CMP-sialic acid transport by endogenous 5-methyl CMP.
13	PDB:6jmqA	0.180	0.161	2.407E-2	403	0.152	0.122	6jmqA.pdb.gz	Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc.
14	PDB:6oz6D	0.197	0.214	3.877E-2	288	0.115	0.128	6oz6D.pdb.gz	Chemical logic of MraY inhibition by antibacterial nucleoside natural products.
15	PDB:4atvA	0.147	0.135	5.484E-2	381	0.118	0.100	4atvA.pdb.gz
16	PDB:7cmhB	0.185	0.151	8.835E-2	458	0.146	0.103	7cmhB.pdb.gz	Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex.
17	PDB:4yzfA	0.151	0.114	1.486E-1	475	0.149	0.101	4yzfA.pdb.gz	Crystal structure of the anion exchanger domain of human erythrocyte band 3.
18	PDB:7b4mA	0.161	0.128	1.846E-1	459	0.106	0.074	7b4mA.pdb.gz
19	PDB:6caaA	0.150	0.122	3.243E-1	477	0.127	0.086	6caaA.pdb.gz
20	PDB:6oyhD	0.194	0.188	3.243E-1	337	0.099	0.095	6oyhD.pdb.gz	Chemical logic of MraY inhibition by antibacterial nucleoside natural products.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P78383	0.0	655	322	1.000	1.000	S35B1_HUMAN Solute carrier family 35 member B1 OS=Homo sapiens OX=9606 GN=SLC35B1 PE=1 SV=1
2	Q9VDD7	3.81e-103	307	338	0.494	0.470	S35B1_DROME Solute carrier family 35 member B1 homolog OS=Drosophila melanogaster OX=7227 GN=meigo PE=2 SV=1
3	Q9BHL2	1.02e-79	248	340	0.444	0.421	Q9BHL2_CAEEL UAA transporter OS=Caenorhabditis elegans OX=6239 GN=hut-1 PE=1 SV=1
4	Q9M9S6	5.88e-50	171	331	0.354	0.344	UTR3_ARATH UDP-galactose/UDP-glucose transporter 3 OS=Arabidopsis thaliana OX=3702 GN=UTR3 PE=1 SV=1
5	O64503	6.71e-44	155	332	0.311	0.301	UTR1_ARATH UDP-galactose/UDP-glucose transporter 1 OS=Arabidopsis thaliana OX=3702 GN=UTR1 PE=1 SV=1
6	Q8WZJ9	1.07e-39	144	322	0.332	0.332	HUT1_SCHPO UDP-galactose transporter homolog 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=hut1 PE=3 SV=1
7	Q9VEI3	5.80e-38	142	465	0.311	0.215	S35B2_DROME Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Drosophila melanogaster OX=7227 GN=sll PE=1 SV=1
8	Q6P101	3.13e-35	134	435	0.307	0.228	Q6P101_DANRE Adenosine 3'-phospho 5'-phosphosulfate transporter 1 precursor OS=Danio rerio OX=7955 GN=papst1 PE=1 SV=1
9	Q91ZN5	6.90e-30	119	431	0.292	0.218	S35B2_MOUSE Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Mus musculus OX=10090 GN=Slc35b2 PE=1 SV=1
10	Q8TB61	2.66e-29	118	432	0.289	0.215	S35B2_HUMAN Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Homo sapiens OX=9606 GN=SLC35B2 PE=1 SV=1
11	Q922Q5	1.70e-23	101	369	0.295	0.257	S35B3_MOUSE Adenosine 3'-phospho 5'-phosphosulfate transporter 2 OS=Mus musculus OX=10090 GN=Slc35b3 PE=2 SV=1
12	Q9H1N7	4.25e-23	100	401	0.295	0.237	S35B3_HUMAN Adenosine 3'-phospho 5'-phosphosulfate transporter 2 OS=Homo sapiens OX=9606 GN=SLC35B3 PE=1 SV=1
13	Q12520	1.24e-21	95.5	339	0.286	0.271	HUT1_YEAST UDP-galactose transporter homolog 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=HUT1 PE=1 SV=1
14	Q8MXJ9	1.58e-18	87.8	425	0.245	0.186	S35B2_CAEEL Adenosine 3'-phospho 5'-phosphosulfate transporter 1 OS=Caenorhabditis elegans OX=6239 GN=pst-1 PE=3 SV=4
15	Q20787	1.99e-16	81.3	364	0.242	0.214	S35B3_CAEEL Adenosine 3'-phospho 5'-phosphosulfate transporter 2 OS=Caenorhabditis elegans OX=6239 GN=pst-2 PE=3 SV=1
16	Q29Q28	6.70e-15	76.6	345	0.236	0.220	UTR2_ARATH UDP-galactose/UDP-glucose transporter 2 OS=Arabidopsis thaliana OX=3702 GN=UTR2 PE=2 SV=1
17	Q9VVD9	3.06e-13	72.0	396	0.286	0.232	S35B3_DROME Adenosine 3'-phospho 5'-phosphosulfate transporter 2 OS=Drosophila melanogaster OX=7227 GN=Papst2 PE=1 SV=2
18	Q9W429	8.07e-13	70.5	352	0.208	0.190	S35B4_DROME UDP-xylose and UDP-N-acetylglucosamine transporter OS=Drosophila melanogaster OX=7227 GN=Efr PE=2 SV=1
19	Q57YB7	1.06e-10	64.7	498	0.196	0.127	Q57YB7_TRYB2 UDP-galactose transporter OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb07.13M20.270 PE=4 SV=1
20	Q969S0	1.05e-08	58.2	331	0.171	0.166	S35B4_HUMAN Nucleotide sugar transporter SLC35B4 OS=Homo sapiens OX=9606 GN=SLC35B4 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00892 EamA	1.4e-10	52.9	EamA-like transporter family
2	PF03151 TPT	1.2e-10	52.8	Triose-phosphate Transporter family
3	PF08449 UAA	8.1e-53	191.2	UAA transporter family

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 61853.ENSNLEP00000003862

Rank	PPI partner	STRING score	Description
1	61853.ENSNLEP00000007988	0.817	DnaJ (Hsp40) homolog, subfamily B, member 11
2	61853.ENSNLEP00000008573	0.780	Mesencephalic astrocyte-derived neurotrophic factor
3	61853.ENSNLEP00000011910	0.698	Transmembrane 9 superfamily protein member 4
4	61853.ENSNLEP00000018592	0.691	Solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
5	61853.ENSNLEP00000007736	0.681	DnaJ homolog subfamily C member 10
6	61853.ENSNLEP00000004418	0.645	Signal recognition particle receptor, B subunit
7	61853.ENSNLEP00000006180	0.644	Lysophosphatidylcholine acyltransferase 3
8	61853.ENSNLEP00000001781	0.637	Cysteine-rich with EGF-like domains 2
9	61853.ENSNLEP00000005645	0.637	Myeloid leukemia factor 2
10	61853.ENSNLEP00000020043	0.637	Ergosterol biosynthesis 28 homolog
11	61853.ENSNLEP00000013589	0.632	Lysophosphatidylcholine acyltransferase 1
12	61853.ENSNLEP00000019111	0.631	Common component of the spliceosome and rRNA processing machinery
13	61853.ENSNLEP00000021847	0.630	Solute carrier family 35 (GDP-fucose transporter), member C1
14	61853.ENSNLEP00000024159	0.622	Uncharacterized protein
15	61853.ENSNLEP00000020139	0.617	Prolylcarboxypeptidase (angiotensinase C)
16	61853.ENSNLEP00000002350	0.612	annotation not available
17	61853.ENSNLEP00000000744	0.602	Protein YIPF
18	61853.ENSNLEP00000002276	0.569	Solute carrier family 37, member 3
19	61853.ENSNLEP00000021445	0.559	Parvin, alpha
20	61853.ENSNLEP00000011328	0.558	Solute carrier family 35, member A4

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0008514	1.000	organic anion transmembrane transporter activity
GO:0000295	1.000	adenine nucleotide transmembrane transporter activity
GO:0005346	1.000	purine ribonucleotide transmembrane transporter activity
GO:1901702	0.996	salt transmembrane transporter activity
GO:0015291	0.996	secondary active transmembrane transporter activity
GO:0005459	0.995	UDP-galactose transmembrane transporter activity
GO:0015297	0.991	antiporter activity
GO:0015217	0.991	ADP transmembrane transporter activity
GO:0005515	0.985	protein binding
GO:0005347	0.902	ATP transmembrane transporter activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.993	cellular process
GO:0006810	0.858	transport
GO:0071702	0.730	organic substance transport
GO:0071704	0.596	organic substance metabolic process
GO:0044238	0.519	primary metabolic process
GO:0006807	0.488	nitrogen compound metabolic process
GO:0065007	0.462	biological regulation
GO:0050789	0.450	regulation of biological process
GO:0055085	0.444	transmembrane transport
GO:0044237	0.424	cellular metabolic process
GO:0032501	0.379	multicellular organismal process
GO:1901264	0.369	carbohydrate derivative transport
GO:0050794	0.358	regulation of cellular process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0031090	1.000	organelle membrane
GO:0005783	1.000	endoplasmic reticulum
GO:0042175	0.997	nuclear outer membrane-endoplasmic reticulum membrane network
GO:0005789	0.990	endoplasmic reticulum membrane
GO:0005794	0.500	Golgi apparatus
GO:0098588	0.378	bounding membrane of organelle
GO:0000139	0.346	Golgi membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

[back to server]