StarFunc result for job id P78410

User Input

>input (334 residues)
MKMASSLAFLLLNFHVSLLLVQLLTPCSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSA
ETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASD
SGKYLCYFQDGDFYEKALVELKVAALGSNLHVEVKGYEDGGIHLECRSTGWYPQPQIQWS
NAKGENIPAVEAPVVADGVGLYEVAASVIMRGGSGEGVSCIIRNSLLGLEKTASISIADP
FFRSAQPWIAALAGTLPILLLLLAGASYFLWRQQKEITALSSEIESEQEMKEMGYAATER
EISLRESLQEELKRKKIQYLTRGEESSSDTNKSA

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:O00478	0.844	0.500	1.015E-51	584	0.904	0.517	O00478.pdb.gz	BT3A3_HUMAN Butyrophilin subfamily 3 member A3 OS=Homo sapiens OX=9606 GN=BTN3A3 PE=1 SV=1
2	AFDB:O00481	0.774	0.513	5.260E-49	513	0.817	0.532	O00481.pdb.gz	BT3A1_HUMAN Butyrophilin subfamily 3 member A1 OS=Homo sapiens OX=9606 GN=BTN3A1 PE=1 SV=3
3	AFDB:Q6UXG8	0.696	0.453	2.830E-32	535	0.335	0.209	Q6UXG8.pdb.gz	BTNL9_HUMAN Butyrophilin-like protein 9 OS=Homo sapiens OX=9606 GN=BTNL9 PE=1 SV=1
4	AFDB:Q13410	0.669	0.436	3.612E-30	526	0.389	0.247	Q13410.pdb.gz	BT1A1_HUMAN Butyrophilin subfamily 1 member A1 OS=Homo sapiens OX=9606 GN=BTN1A1 PE=1 SV=3
5	AFDB:A0A0G2K9U4	0.567	0.611	3.812E-30	303	0.353	0.389	A0A0G2K9U4.pdb.gz	A0A0G2K9U4_RAT Butyrophilin-like 8 OS=Rattus norvegicus OX=10116 GN=Btnl8 PE=4 SV=2
6	AFDB:A2CG22	0.598	0.411	6.895E-30	539	0.371	0.230	A2CG22.pdb.gz	A2CG22_MOUSE Butyrophilin-like 6 OS=Mus musculus OX=10090 GN=Btnl6 PE=1 SV=1
7	AFDB:Q6MG92	0.568	0.366	8.104E-30	588	0.368	0.209	Q6MG92.pdb.gz	Q6MG92_RAT Butyrophilin-like 8 OS=Rattus norvegicus OX=10116 GN=Btnl8 PE=3 SV=1
8	AFDB:Q7KYR7	0.660	0.425	4.306E-29	527	0.380	0.241	Q7KYR7.pdb.gz	BT2A1_HUMAN Butyrophilin subfamily 2 member A1 OS=Homo sapiens OX=9606 GN=BTN2A1 PE=1 SV=3
9	AFDB:A4QPC6	0.619	0.407	5.950E-29	514	0.365	0.237	A4QPC6.pdb.gz	BT2A2_MOUSE Butyrophilin subfamily 2 member A2 OS=Mus musculus OX=10090 GN=Btn2a2 PE=1 SV=1
10	AFDB:Q7TST0	0.678	0.455	1.569E-28	509	0.320	0.210	Q7TST0.pdb.gz	BTNL1_MOUSE Butyrophilin-like protein 1 OS=Mus musculus OX=10090 GN=Btnl1 PE=2 SV=3
11	PDB:1ngwH	0.295	0.438	1.639E-12	216	0.120	0.185	1ngwH.pdb.gz	Structural evidence for substrate strain in antibody catalysis
12	PDB:1q0xL	0.286	0.416	6.305E-12	212	0.105	0.165	1q0xL.pdb.gz
13	PDB:1jnhA	0.267	0.396	7.821E-12	208	0.105	0.168	1jnhA.pdb.gz	Highly specific anti-estradiol antibodies: structural characterisation and binding diversity.
14	PDB:2qhrL	0.319	0.429	2.701E-11	218	0.117	0.179	2qhrL.pdb.gz	Complex of a protective antibody with its Ebola virus GP peptide epitope: unusual features of a V lambda x light chain.
15	PDB:4adfM	0.475	0.788	2.701E-11	191	0.123	0.215	4adfM.pdb.gz
16	PDB:1aqkL	0.261	0.384	3.350E-11	216	0.096	0.148	1aqkL.pdb.gz
17	PDB:1igaA	0.280	0.203	4.629E-11	475	0.123	0.086	1igaA.pdb.gz
18	PDB:2ig2H	0.300	0.397	5.156E-11	238	0.117	0.164	2ig2H.pdb.gz
19	PDB:6dcvA	0.286	0.391	5.742E-11	220	0.090	0.136	6dcvA.pdb.gz
20	PDB:1fdlL	0.272	0.396	6.060E-11	214	0.084	0.131	1fdlL.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	O00478	0.0	621	584	0.904	0.517	BT3A3_HUMAN Butyrophilin subfamily 3 member A3 OS=Homo sapiens OX=9606 GN=BTN3A3 PE=1 SV=1
2	O00481	0.0	512	513	0.820	0.534	BT3A1_HUMAN Butyrophilin subfamily 3 member A1 OS=Homo sapiens OX=9606 GN=BTN3A1 PE=1 SV=3
3	P78410	0.0	685	334	1.000	1.000	BT3A2_HUMAN Butyrophilin subfamily 3 member A2 OS=Homo sapiens OX=9606 GN=BTN3A2 PE=1 SV=2
4	Q13410	2.41e-77	248	526	0.404	0.257	BT1A1_HUMAN Butyrophilin subfamily 1 member A1 OS=Homo sapiens OX=9606 GN=BTN1A1 PE=1 SV=3
5	Q7KYR7	3.36e-72	234	527	0.371	0.235	BT2A1_HUMAN Butyrophilin subfamily 2 member A1 OS=Homo sapiens OX=9606 GN=BTN2A1 PE=1 SV=3
6	M0RD77	2.76e-71	226	313	0.368	0.393	M0RD77_RAT Butyrophilin-like 8 OS=Rattus norvegicus OX=10116 GN=Btnl8 PE=4 SV=1
7	A0A0G2K9U4	6.06e-69	221	346	0.341	0.329	A0A0G2K9U4_RAT Butyrophilin-like 8 OS=Rattus norvegicus OX=10116 GN=Btnl8 PE=4 SV=2
8	Q8WVV5	4.32e-67	221	523	0.356	0.228	BT2A2_HUMAN Butyrophilin subfamily 2 member A2 OS=Homo sapiens OX=9606 GN=BTN2A2 PE=1 SV=2
9	Q6MG92	5.71e-67	222	588	0.356	0.202	Q6MG92_RAT Butyrophilin-like 8 OS=Rattus norvegicus OX=10116 GN=Btnl8 PE=3 SV=1
10	A2CG22	1.87e-66	219	539	0.368	0.228	A2CG22_MOUSE Butyrophilin-like 6 OS=Mus musculus OX=10090 GN=Btnl6 PE=1 SV=1
11	A4QPC6	1.04e-64	214	514	0.323	0.210	BT2A2_MOUSE Butyrophilin subfamily 2 member A2 OS=Mus musculus OX=10090 GN=Btn2a2 PE=1 SV=1
12	Q62556	3.03e-61	206	524	0.335	0.214	BT1A1_MOUSE Butyrophilin subfamily 1 member A1 OS=Mus musculus OX=10090 GN=Btn1a1 PE=1 SV=2
13	Q6UXG8	2.07e-57	196	535	0.311	0.194	BTNL9_HUMAN Butyrophilin-like protein 9 OS=Homo sapiens OX=9606 GN=BTNL9 PE=1 SV=1
14	Q9UIR0	7.37e-52	179	455	0.263	0.193	BTNL2_HUMAN Butyrophilin-like protein 2 OS=Homo sapiens OX=9606 GN=BTNL2 PE=1 SV=1
15	A7TZE6	4.81e-51	175	364	0.263	0.242	SKIT1_MOUSE Selection and upkeep of intraepithelial T-cells protein 1 OS=Mus musculus OX=10090 GN=Skint1 PE=1 SV=1
16	Q7TST0	3.90e-50	176	509	0.314	0.206	BTNL1_MOUSE Butyrophilin-like protein 1 OS=Mus musculus OX=10090 GN=Btnl1 PE=2 SV=3
17	Q6UXE8	4.26e-49	172	466	0.269	0.193	BTNL3_HUMAN Butyrophilin-like protein 3 OS=Homo sapiens OX=9606 GN=BTNL3 PE=1 SV=2
18	Q6UX41	1.24e-44	161	500	0.234	0.156	BTNL8_HUMAN Butyrophilin-like protein 8 OS=Homo sapiens OX=9606 GN=BTNL8 PE=1 SV=1
19	O70355	6.46e-43	155	454	0.260	0.192	BTNL2_MOUSE Butyrophilin-like protein 2 OS=Mus musculus OX=10090 GN=Btnl2 PE=1 SV=2
20	Q63345	4.33e-31	119	245	0.165	0.224	MOG_RAT Myelin-oligodendrocyte glycoprotein OS=Rattus norvegicus OX=10116 GN=Mog PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF08205 C2-set_2	64	15.0	CD80-like C2-set immunoglobulin domain
2	PF19904 DUF6377	95	14.0	Domain of unknown function (DUF6377)
3	PF07679 I-set	0.00034	31.9	Immunoglobulin I-set domain
4	PF00047 ig	0.077	24.5	Immunoglobulin domain
5	PF13895 Ig_2	11	17.7	Immunoglobulin domain
6	PF13927 Ig_3	0.0006	31.6	Immunoglobulin domain
7	PF09307 MHC2-interact	3e+02	12.8	CLIP, MHC2 interacting
8	PF07686 V-set	3.6e-10	51.4	Immunoglobulin V-set domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000348751

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000289361	0.967	Butyrophilin subfamily 3 member A1
2	9606.ENSP00000244519	0.914	Butyrophilin subfamily 3 member A3
3	9606.ENSP00000340510	0.558	Periplakin

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0002376	0.991	immune system process
GO:0065007	0.986	biological regulation
GO:0050896	0.986	response to stimulus
GO:0032649	0.982	regulation of type II interferon production
GO:0048518	0.973	positive regulation of biological process
GO:0051240	0.942	positive regulation of multicellular organismal process
GO:0032729	0.932	positive regulation of type II interferon production
GO:0002456	0.922	T cell mediated immunity
GO:0009987	0.600	cellular process
GO:0032501	0.467	multicellular organismal process
GO:0050794	0.412	regulation of cellular process
GO:0002682	0.373	regulation of immune system process
GO:0050778	0.363	positive regulation of immune response
GO:0046649	0.355	lymphocyte activation

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005886	1.000	plasma membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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