StarFunc result for job id Q00341

User Input

>input (1268 residues)
MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEP
SGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLA
KDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKT
ATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGP
YNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAV
EVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAK
ANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVA
QEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNL
IRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEV
IINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKG
GANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSI
PAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLA
EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKE
DAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRS
GTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQIT
RDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKC
EAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAI
TGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRL
EHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHA
RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLAD
VVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPK
TLPWGPKR

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:A0A024R4E5	0.429	0.429	0.000	1268	0.999	0.999	A0A024R4E5.pdb.gz	A0A024R4E5_HUMAN High density lipoprotein binding protein OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=1
2	AFDB:F1R9Y8	0.360	0.359	0.000	1272	0.796	0.793	F1R9Y8.pdb.gz
3	AFDB:Q7KN75	0.397	0.390	0.000	1301	0.474	0.462	Q7KN75.pdb.gz	Q7KN75_DROME Dodeca-satellite-binding protein 1, isoform A OS=Drosophila melanogaster OX=7227 GN=Dp1 PE=1 SV=1
4	AFDB:O59810	0.191	0.188	1.348E-83	1291	0.226	0.222	O59810.pdb.gz	VGL1_SCHPO Vigilin 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=vgl1 PE=1 SV=2
5	AFDB:P06105	0.164	0.169	2.996E-67	1222	0.196	0.204	P06105.pdb.gz	SC160_YEAST Protein SCP160 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SCP160 PE=1 SV=3
6	AFDB:Q8IJS7	0.111	0.120	3.630E-26	1139	0.116	0.129	Q8IJS7.pdb.gz	Q8IJS7_PLAF7 PRE-binding protein OS=Plasmodium falciparum (isolate 3D7) OX=36329 GN=PF3D7_1011800 PE=4 SV=1
7	AFDB:Q07834	0.138	0.201	5.533E-23	825	0.075	0.115	Q07834.pdb.gz	YL032_YEAST KH domain-containing protein YLL032C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=YLL032C PE=1 SV=1
8	AFDB:Q2EMV9	0.135	0.101	1.161E-21	1817	0.081	0.057	Q2EMV9.pdb.gz	PAR14_MOUSE Protein mono-ADP-ribosyltransferase PARP14 OS=Mus musculus OX=10090 GN=Parp14 PE=1 SV=3
9	AFDB:Q460N5	0.133	0.101	4.843E-21	1801	0.088	0.062	Q460N5.pdb.gz	PAR14_HUMAN Protein mono-ADP-ribosyltransferase PARP14 OS=Homo sapiens OX=9606 GN=PARP14 PE=1 SV=3
10	AFDB:O74359	0.121	0.210	2.757E-20	663	0.074	0.142	O74359.pdb.gz	MUG60_SCHPO Meiotically up-regulated gene 60 protein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mug60 PE=1 SV=1
11	PDB:5wq8A	0.092	0.186	2.491E-6	496	0.040	0.103	5wq8A.pdb.gz
12	PDB:5wq7A	0.096	0.201	4.338E-5	472	0.054	0.144	5wq7A.pdb.gz
13	PDB:7mqaSW	0.062	0.300	9.726E-5	195	0.022	0.144	7mqaSW.pdb.gz	Nucleolar maturation of the human small subunit processome.
14	PDB:1q2lA	0.048	0.060	1.701E-4	937	0.082	0.111	1q2lA.pdb.gz	Crystal Structure of pitrilysin, the prototype of insulin-degrading enzymes
15	PDB:7ajuJJ	0.073	0.310	1.926E-4	199	0.015	0.095	7ajuJJ.pdb.gz	Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome.
16	PDB:5vsuA	0.054	0.135	2.181E-4	387	0.034	0.111	5vsuA.pdb.gz	Architecture of the U6 snRNP reveals specific recognition of 3'-end processed U6 snRNA.
17	PDB:7z1mO	0.041	0.068	9.100E-4	570	0.066	0.147	7z1mO.pdb.gz	Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals.
18	PDB:7mq8NY	0.077	0.250	1.030E-3	274	0.035	0.161	7mq8NY.pdb.gz	Nucleolar maturation of the human small subunit processome.
19	PDB:7ogkA	0.067	0.110	1.167E-3	695	0.048	0.088	7ogkA.pdb.gz	A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation.
20	PDB:5wlnA	0.072	0.173	1.592E-3	396	0.036	0.116	5wlnA.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	A0A024R4E5	0.0	2582	1268	0.999	0.999	A0A024R4E5_HUMAN High density lipoprotein binding protein OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=1
2	H7C0A4	0.0	658	332	0.261	0.997	H7C0A4_HUMAN High density lipoprotein binding protein (Fragment) OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=8
3	Q00341	0.0	2585	1268	1.000	1.000	VIGLN_HUMAN Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2
4	Q7KN75	0.0	1150	1301	0.472	0.460	Q7KN75_DROME Dodeca-satellite-binding protein 1, isoform A OS=Drosophila melanogaster OX=7227 GN=Dp1 PE=1 SV=1
5	Q7KN84	0.0	834	897	0.346	0.489	Q7KN84_DROME K Homology domain-containing protein OS=Drosophila melanogaster OX=7227 GN=Dp1 PE=2 SV=1
6	Q7ZU44	0.0	1991	1208	0.761	0.799	Q7ZU44_DANRE High density lipoprotein-binding protein (Vigilin) OS=Danio rerio OX=7955 GN=hdlbp PE=1 SV=1
7	Q9U982	0.0	1150	1301	0.473	0.461	Q9U982_DROME Drosophila dodeca-satellite protein 1 OS=Drosophila melanogaster OX=7227 GN=Dp1 PE=2 SV=1
8	C9JIZ1	9.18e-152	457	224	0.176	0.996	C9JIZ1_HUMAN High density lipoprotein binding protein (Fragment) OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2
9	C9J5E5	1.36e-149	451	221	0.174	0.995	C9J5E5_HUMAN High density lipoprotein binding protein (Fragment) OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2
10	O59810	2.82e-68	254	1291	0.215	0.211	VGL1_SCHPO Vigilin 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=vgl1 PE=1 SV=2
11	Q95T04	5.21e-55	195	282	0.090	0.404	Q95T04_DROME LD29992p OS=Drosophila melanogaster OX=7227 GN=Dp1 PE=2 SV=1
12	P06105	4.62e-42	171	1222	0.178	0.185	SC160_YEAST Protein SCP160 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SCP160 PE=1 SV=3
13	Q99MQ1	3.32e-12	73.6	977	0.062	0.080	BICC1_MOUSE Protein bicaudal C homolog 1 OS=Mus musculus OX=10090 GN=Bicc1 PE=1 SV=1
14	Q9H694	1.17e-11	72.0	974	0.057	0.074	BICC1_HUMAN Protein bicaudal C homolog 1 OS=Homo sapiens OX=9606 GN=BICC1 PE=1 SV=2
15	Q32PX7	2.48e-08	60.8	639	0.069	0.138	FUBP1_RAT Far upstream element-binding protein 1 OS=Rattus norvegicus OX=10116 GN=Fubp1 PE=1 SV=1
16	Q17936	1.43e-07	58.2	611	0.062	0.129	Q17936_CAEEL K Homology domain-containing protein OS=Caenorhabditis elegans OX=6239 GN=fubl-1 PE=1 SV=1
17	Q91WJ8	2.02e-07	57.8	651	0.068	0.132	FUBP1_MOUSE Far upstream element-binding protein 1 OS=Mus musculus OX=10090 GN=Fubp1 PE=1 SV=1
18	Q96AE4	6.46e-07	56.2	644	0.067	0.132	FUBP1_HUMAN Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3
19	E9PEB5	8.64e-07	55.8	655	0.067	0.130	E9PEB5_HUMAN Far upstream element binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=1
20	Q8UVD9	1.21e-06	55.5	769	0.059	0.098	FUBP2_CHICK Far upstream element-binding protein 2 OS=Gallus gallus OX=9031 GN=KHSRP PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00936 BMC	1.4	20.3	BMC domain
2	PF09869 DUF2096	3.1e+02	12.8	Uncharacterized protein conserved in archaea (DUF2096)
3	PF15039 DUF4530	57	15.3	Domain of unknown function (DUF4530)
4	PF00013 KH_1	3.6e-185	611.4	KH domain
5	PF07650 KH_2	9.2e-16	68.8	KH domain
6	PF13184 KH_5	46	15.6	NusA-like KH domain
7	PF13691 Lactamase_B_4	81	14.3	tRNase Z endonuclease
8	PF02630 SCO1-SenC	5.1	18.5	SCO1/SenC
9	PF14611 SLS	2.6e-15	68.5	Mitochondrial inner-membrane-bound regulator

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000375836

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000357459	0.859	Double-stranded RNA-specific adenosine deaminase
2	9606.ENSP00000200676	0.828	Cholesteryl ester transfer protein
3	9606.ENSP00000350425	0.821	Apolipoprotein A-IV
4	9606.ENSP00000337976	0.786	Histone-lysine N-methyltransferase SUV39H1
5	9606.ENSP00000227667	0.778	Apolipoprotein C-III
6	9606.ENSP00000236850	0.767	Apolipoprotein A-I
7	9606.ENSP00000426909	0.767	Receptor of activated protein C kinase 1
8	9606.ENSP00000313454	0.751	Ubiquitin-like modifier-activating enzyme 6
9	9606.ENSP00000287878	0.732	5'-AMP-activated protein kinase subunit gamma-2
10	9606.ENSP00000323867	0.732	5'-AMP-activated protein kinase subunit gamma-1
11	9606.ENSP00000233242	0.730	Apolipoprotein B-100
12	9606.ENSP00000356790	0.727	Sodium/potassium-transporting ATPase subunit beta-1
13	9606.ENSP00000480150	0.726	Hypoxia up-regulated protein 1
14	9606.ENSP00000458986	0.707	Clustered mitochondria protein homolog
15	9606.ENSP00000356969	0.698	Apolipoprotein A-II
16	9606.ENSP00000385746	0.690	Spermine synthase
17	9606.ENSP00000243253	0.684	Protein transport protein Sec61 subunit alpha isoform 1
18	9606.ENSP00000470142	0.683	Regulator of nonsense transcripts 1
19	9606.ENSP00000252486	0.678	Apolipoprotein E
20	9606.ENSP00000324173	0.677	78 kDa glucose-regulated protein

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0003729	1.000	mRNA binding
GO:0008289	0.998	lipid binding
GO:0045296	0.995	cadherin binding
GO:0003730	0.988	mRNA 3'-UTR binding
GO:0003697	0.928	single-stranded DNA binding
GO:1990837	0.872	sequence-specific double-stranded DNA binding
GO:0003696	0.615	satellite DNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.989	cellular process
GO:0008152	0.963	metabolic process
GO:0071704	0.954	organic substance metabolic process
GO:0044238	0.942	primary metabolic process
GO:0008202	0.927	steroid metabolic process
GO:1902652	0.917	secondary alcohol metabolic process
GO:0016125	0.917	sterol metabolic process
GO:0050896	0.915	response to stimulus
GO:0051716	0.861	cellular response to stimulus
GO:0008203	0.843	cholesterol metabolic process
GO:0042221	0.691	response to chemical
GO:0010033	0.658	response to organic substance
GO:0065007	0.639	biological regulation
GO:0009719	0.615	response to endogenous stimulus
GO:0044237	0.584	cellular metabolic process
GO:0050789	0.580	regulation of biological process
GO:0071310	0.556	cellular response to organic substance
GO:0050794	0.453	regulation of cellular process
GO:0009725	0.399	response to hormone

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005829	1.000	cytosol
GO:0016020	0.979	membrane
GO:0043231	0.879	intracellular membrane-bounded organelle
GO:0032991	0.797	protein-containing complex
GO:0071944	0.784	cell periphery
GO:0005886	0.713	plasma membrane
GO:0043232	0.453	intracellular non-membrane-bounded organelle
GO:0005634	0.395	nucleus

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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