StarFunc result for job id Q17RW2

User Input

>input (1714 residues)
MHLRAHRTRRGKVSPTAKTKSLLHFIVLCVAGVVVHAQEQGIDILHQLGLGGKDVRHSSP
ATAVPSASTPLPQGVHLTESGVIFKNDAYIETPFVKILPVNLGQPFTILTGLQSHRVNNA
FLFSIRNKNRLQLGVQLLPKKLVVHIRGKQPAVFNYSVHDEQWHSFAITIRNQSVSMFVE
CGKKYFSTETIPEVQTFDSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQ
QCRQADKYQPETSIPCTTLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSET
VYKRQEHQISRSQLSSLQSGNVSAVDLTNHGIQAKEMITEEDTQTNFSLSVTTHRISEAK
MNTKEKFSSLLNMSDNITQHDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNE
LMEMQPILNTSLHRVTNEPSVDNHLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNT
MLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPG
FSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG
RQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRG
PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQG
TAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPG
QNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKG
EVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPG
PIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIG
KTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESG
LQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKG
EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG
KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVL
GPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGER
GSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIR
GGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPC
GDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGII
GPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDINAAIQALIESNTALQM
ESYQNTEVTLIDHSEEIFKTLNYLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKY
WIDPNLGCPSDAIEVFCNFSAGGQTCLPPVSVTKLEFGVGKVQMNFLHLLSSEATHIITI
HCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSWHKATFLFH
TQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q17RW2	1.000	1.000	0.000	1714	1.000	1.000	Q17RW2.pdb.gz	COOA1_HUMAN Collagen alpha-1(XXIV) chain OS=Homo sapiens OX=9606 GN=COL24A1 PE=1 SV=2
2	AFDB:Q30D77	0.228	0.226	0.000	1733	0.783	0.774	Q30D77.pdb.gz	COOA1_MOUSE Collagen alpha-1(XXIV) chain OS=Mus musculus OX=10090 GN=Col24a1 PE=2 SV=2
3	AFDB:A0MSJ1	0.134	0.139	1.742E-87	1658	0.471	0.487	A0MSJ1.pdb.gz	CRA1B_DANRE Collagen alpha-1(XXVII) chain B OS=Danio rerio OX=7955 GN=col27a1b PE=2 SV=1
4	AFDB:Q5QNQ9	0.131	0.123	1.395E-84	1845	0.479	0.445	Q5QNQ9.pdb.gz	CORA1_MOUSE Collagen alpha-1(XXVII) chain OS=Mus musculus OX=10090 GN=Col27a1 PE=2 SV=1
5	AFDB:Q8IZC6	0.186	0.175	7.047E-83	1860	0.481	0.443	Q8IZC6.pdb.gz	CORA1_HUMAN Collagen alpha-1(XXVII) chain OS=Homo sapiens OX=9606 GN=COL27A1 PE=1 SV=1
6	AFDB:C7DZK3	0.126	0.122	2.902E-77	1783	0.463	0.445	C7DZK3.pdb.gz	CRA1A_DANRE Collagen alpha-1(XXVII) chain A OS=Danio rerio OX=7955 GN=col27a1a PE=2 SV=1
7	AFDB:Q9JI03	0.119	0.111	5.639E-46	1840	0.377	0.352	Q9JI03.pdb.gz	CO5A1_RAT Collagen alpha-1(V) chain OS=Rattus norvegicus OX=10116 GN=Col5a1 PE=1 SV=1
8	AFDB:I3ISS1	0.121	0.116	1.702E-45	1803	0.358	0.341	I3ISS1.pdb.gz
9	AFDB:P12107	0.119	0.113	4.195E-44	1806	0.361	0.342	P12107.pdb.gz	COBA1_HUMAN Collagen alpha-1(XI) chain OS=Homo sapiens OX=9606 GN=COL11A1 PE=1 SV=4
10	AFDB:P25940	0.117	0.115	3.824E-43	1745	0.355	0.348	P25940.pdb.gz	CO5A3_HUMAN Collagen alpha-3(V) chain OS=Homo sapiens OX=9606 GN=COL5A3 PE=1 SV=3
11	PDB:3v0aB	0.077	0.113	1.330E-6	1150	0.013	0.019	3v0aB.pdb.gz	Botulinum neurotoxin is shielded by NTNHA in an interlocked complex.
12	PDB:7zl1A	0.068	0.456	2.882E-6	215	0.017	0.135	7zl1A.pdb.gz
13	PDB:7qfqA	0.071	0.091	6.245E-6	1291	0.009	0.012	7qfqA.pdb.gz
14	PDB:4pbpB	0.070	0.489	1.784E-5	210	0.012	0.095	4pbpB.pdb.gz	Crystal structures for short-chain pentraxin from zebrafish demonstrate a cyclic trimer with new recognition and effector faces.
15	PDB:3o12A	0.067	0.418	3.100E-5	185	0.012	0.114	3o12A.pdb.gz
16	PDB:2a3wA	0.066	0.465	3.462E-5	204	0.013	0.113	2a3wA.pdb.gz	Ligand-assisted Aggregation of Proteins: DIMERIZATION OF SERUM AMYLOID P COMPONENT BY BIVALENT LIGANDS.
17	PDB:8a7eC	0.076	0.085	6.016E-5	1524	0.017	0.019	8a7eC.pdb.gz	Structure of the proteolytic enzyme PAPP-A with the endogenous inhibitor stanniocalcin-2 reveals its inhibitory mechanism.
18	PDB:5n0cA	0.075	0.097	6.358E-5	1293	0.014	0.019	5n0cA.pdb.gz	The structure of the tetanus toxin reveals pH-mediated domain dynamics.
19	PDB:7ufgB	0.072	0.102	6.358E-5	1182	0.016	0.024	7ufgB.pdb.gz	Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
20	PDB:7ufgA	0.073	0.106	9.360E-5	1151	0.015	0.023	7ufgA.pdb.gz	Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	A0MSJ1	0.0	1146	1658	0.471	0.487	CRA1B_DANRE Collagen alpha-1(XXVII) chain B OS=Danio rerio OX=7955 GN=col27a1b PE=2 SV=1
2	C7DZK3	0.0	781	1783	0.371	0.357	CRA1A_DANRE Collagen alpha-1(XXVII) chain A OS=Danio rerio OX=7955 GN=col27a1a PE=2 SV=1
3	Q17RW2	0.0	3302	1714	1.000	1.000	COOA1_HUMAN Collagen alpha-1(XXIV) chain OS=Homo sapiens OX=9606 GN=COL24A1 PE=1 SV=2
4	Q30D77	0.0	2170	1733	0.784	0.775	COOA1_MOUSE Collagen alpha-1(XXIV) chain OS=Mus musculus OX=10090 GN=Col24a1 PE=2 SV=2
5	Q5QNQ9	0.0	828	1845	0.378	0.351	CORA1_MOUSE Collagen alpha-1(XXVII) chain OS=Mus musculus OX=10090 GN=Col27a1 PE=2 SV=1
6	P02466	3.55e-137	463	1372	0.306	0.382	CO1A2_RAT Collagen alpha-2(I) chain OS=Rattus norvegicus OX=10116 GN=Col1a2 PE=1 SV=3
7	Q8IZC6	2.52e-122	428	1860	0.180	0.166	CORA1_HUMAN Collagen alpha-1(XXVII) chain OS=Homo sapiens OX=9606 GN=COL27A1 PE=1 SV=1
8	Q01149	3.70e-115	400	1372	0.278	0.347	CO1A2_MOUSE Collagen alpha-2(I) chain OS=Mus musculus OX=10090 GN=Col1a2 PE=1 SV=2
9	P08120	3.14e-111	394	1779	0.303	0.292	CO4A1_DROME Collagen alpha-1(IV) chain OS=Drosophila melanogaster OX=7227 GN=Col4a1 PE=1 SV=3
10	Q6IQX2	5.63e-107	376	1352	0.283	0.359	Q6IQX2_DANRE Collagen alpha-2(I) chain precursor OS=Danio rerio OX=7955 GN=alpha2(I) PE=1 SV=1
11	P02467	5.11e-106	373	1363	0.274	0.344	CO1A2_CHICK Collagen alpha-2(I) chain OS=Gallus gallus OX=9031 GN=COL1A2 PE=1 SV=3
12	A0A0S2Z3H5	4.73e-103	364	1366	0.275	0.345	A0A0S2Z3H5_HUMAN Collagen type I alpha 2 isoform 1 (Fragment) OS=Homo sapiens OX=9606 GN=COL1A2 PE=2 SV=1
13	P08123	4.73e-103	364	1366	0.275	0.345	CO1A2_HUMAN Collagen alpha-2(I) chain OS=Homo sapiens OX=9606 GN=COL1A2 PE=1 SV=7
14	Q9VMV5	1.09e-102	368	1940	0.282	0.249	Q9VMV5_DROME Viking, isoform A OS=Drosophila melanogaster OX=7227 GN=vkg PE=1 SV=1
15	O18407	2.02e-100	360	1761	0.281	0.274	O18407_DROME Collagen type IV alpha 2 OS=Drosophila melanogaster OX=7227 GN=vkg PE=1 SV=1
16	Q9JLI2	2.21e-99	357	1739	0.306	0.302	Q9JLI2_MOUSE Collagen type V alpha 3 chain OS=Mus musculus OX=10090 GN=Col5a3 PE=1 SV=1
17	H0VHD0	3.40e-99	352	1287	0.253	0.337	H0VHD0_CAVPO Collagen type I alpha 2 chain OS=Cavia porcellus OX=10141 GN=COL1A2 PE=4 SV=2
18	P17139	2.47e-93	338	1759	0.285	0.278	CO4A1_CAEEL Collagen alpha-1(IV) chain OS=Caenorhabditis elegans OX=6239 GN=emb-9 PE=1 SV=5
19	Q64739	6.37e-93	337	1736	0.303	0.300	COBA2_MOUSE Collagen alpha-2(XI) chain OS=Mus musculus OX=10090 GN=Col11a2 PE=2 SV=3
20	B3DLK0	3.29e-92	332	1421	0.255	0.308	B3DLK0_DANRE Col2a1a protein OS=Danio rerio OX=7955 GN=col2a1 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF01410 COLFI	1.2e-42	157.4	Fibrillar collagen C-terminal domain
2	PF01391 Collagen	1.9e-149	496.8	Collagen triple helix repeat (20 copies)
3	PF02210 Laminin_G_2	0.86	21.6	Laminin G domain
4	PF13385 Laminin_G_3	5.5	18.5	Concanavalin A-like lectin/glucanases superfamily

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000359603

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000362304	0.940	A disintegrin and metalloproteinase with thrombospondin motifs 14
2	9606.ENSP00000223061	0.932	Procollagen C-endopeptidase enhancer 1
3	9606.ENSP00000061240	0.929	Tolloid-like protein 1
4	9606.ENSP00000251582	0.926	A disintegrin and metalloproteinase with thrombospondin motifs 2
5	9606.ENSP00000305714	0.925	Bone morphogenetic protein 1
6	9606.ENSP00000295992	0.923	Procollagen C-endopeptidase enhancer 2
7	9606.ENSP00000350630	0.921	Tolloid-like protein 2
8	9606.ENSP00000286657	0.912	A disintegrin and metalloproteinase with thrombospondin motifs 3
9	9606.ENSP00000263556	0.910	Prolyl 4-hydroxylase subunit alpha-1
10	9606.ENSP00000401749	0.907	Prolyl 4-hydroxylase subunit alpha-3
11	9606.ENSP00000384999	0.906	Prolyl 4-hydroxylase subunit alpha-2
12	9606.ENSP00000323696	0.741	Cartilage-associated protein
13	9606.ENSP00000354960	0.729	Procollagen galactosyltransferase 2
14	9606.ENSP00000236040	0.722	Prolyl 3-hydroxylase 1
15	9606.ENSP00000258341	0.696	Laminin subunit gamma-1
16	9606.ENSP00000223127	0.686	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
17	9606.ENSP00000282903	0.685	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
18	9606.ENSP00000196061	0.680	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
19	9606.ENSP00000434412	0.669	Serpin H1
20	9606.ENSP00000375899	0.650	Nuclear body protein SP140

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0005198	0.759	structural molecule activity
GO:0005201	0.748	extracellular matrix structural constituent
GO:0030020	0.400	extracellular matrix structural constituent conferring tensile strength

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0032502	0.991	developmental process
GO:0009987	0.988	cellular process
GO:0048856	0.953	anatomical structure development
GO:0007275	0.683	multicellular organism development
GO:0048731	0.521	system development
GO:0065007	0.302	biological regulation

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0012505	0.999	endomembrane system
GO:0005737	0.999	cytoplasm
GO:0062023	0.999	collagen-containing extracellular matrix
GO:0043231	0.999	intracellular membrane-bounded organelle
GO:0070013	0.998	intracellular organelle lumen
GO:0005576	0.988	extracellular region
GO:0005783	0.965	endoplasmic reticulum
GO:0005788	0.951	endoplasmic reticulum lumen
GO:0032991	0.472	protein-containing complex

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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