StarFunc result for job id Q2KJY2

User Input

>input (2108 residues)
MNSVAGNKERLAVSTRGKKYGVNEVCSPTKPAAPFSPESWYRKAYEESRAGSRPTPEGAG
SALGSSGTPSPGSGTSSPSSFTGSPGPASPGIGTSSPGSLGGSPGFGTGSPGSGSGGGSS
PGSDRGVWCENCNARLVELKRQALRLLLPGPFPGKDPAFSAVIHDKLQVPNTIRKAWNDR
DNRCDICATHLNQLKQEAIQMVLTLEQAAGSEHYDASPCSPPPLSNIPTLVGSRHVGGLQ
QPRDWAFVPAPCATSNYTGFANKHGSKPSSLGVSNGAEKKSGSPTHQAKVSLQMATSPSN
GNILNSVAIQAHQYLDGTWSLSRTNGVTLYPYQISQLMTESSREGLTEAVLNRYNADKPS
ACSVPASQGSCVASETSTGTSVAASFFARAAQKLNLSSKKKKHRPSTSSAAEPPLFATSF
SGILQTSPPPAPPCLLRAVNKVKDTPGLGKVKVMLRICSTLARDTSESSSFLKVDPRKKQ
ITLYDPLTCGGQNAFQKRGNQVPPKMFAFDAVFPQDASQAEVCAGTVAEVIQSVVNGADG
CVFCFGHAKLGKSYTMIGKDDSMQNLGIIPCAISWLFKLINERKEKTGARFSVRVSAVEV
WGKEENLRDLLSEVATGSLQDGQSPGVYLCEDPICGTQLQNQSELRAPTAEKAAFFLDAA
IASRRSHQQDCDEDDHRNSHVFFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCVKALS
KNREGGSGLCLSLSALGNVILALVNGSKHIPYKESKLAMLLRESLGNMNCRTTMIAHISA
AVGSYAETLSTIQIASRVLRMKKKKTKYTSSSSGGESSCEEGRMRRPTQLRPFHTRATVD
PDFPIAHLSSDPDYSSSSEQSCDTVIYIGPNGTALSDKELTDNEGPPDFVPIVPALQKTR
GDSRPAEAGEAAAGKSERDCLKCNTFAELQERLDCIDGSEEPSSFPFEELPAQFGPEQAS
RGPRLSQAAGASPLSESDKEDNGSEGQLTNREGPELPASKMQRSHSPVPAAAPAHSPSPA
SPRSVPGSSSQHSASPLVQSPSLQSSRESLNSCGFVEGKPRPMGSPRLGIASLSKTSEYK
PPSSPSQRCKVYTQKGVLPSPAPLPPSSKDSGVASRESLLQPEVRTPPVGMSPQVLKKSM
SAGSEGFPETPVDDEQQAATPSESKKEILSTTMVTVQQPLELNGEDELVFTLVEELTISG
VLDSGRPTSIISFNSDCSARALASGSRPVSIISSISEDLECYSSTAPVSEVSITQFLPLP
KMSLDEKAQDAGSRRSSISSWLSEMSAGSEGEQSCHSFIAQTCFGHGEAMAEPVASEFVS
SLQNTAVVCREKPKASPDNLLILSEMGDDSFNKAAPIKGCKISTVSKAMVTISNTANLSS
CEGYIPMKTNITVYPCIAMSPRNIQEPEAPTATPKAGPTLAQSRESKENSAKKEMKFEDP
WLKREEEVKKETAHPNEEGMMRCETATGPSNAETRAEQEQDGKPSPGDRLSSSSGEVSAS
PVTDNFRRVVDGCEMALPGLATQSPVHPNKSVKSSSLPRAFQKASRQEEPDSLSYYCAAE
TNGVGAASGTPPSKATLEGKVASPKHCVLARPKGTPPLPPVRKSSLDQKNRASPQHSASG
SGTSSPLNQPAAFPAGLPDEPSGKTKDASSSSKLFSAKLEQLASRSNSLGRATVSHYECL
SLERAESLSSVSSRLHAGKDGTMPRAGRSLGRSAGTSPPSSGASPKAGQSKISAVSRLLL
ASPRARGPSASTTKTLSFSTKSLPQAVGQGSSSPPGGKHTPWSTQSLSRNRSSGLASKLP
LRAVSGRISELLQGGAGARGLQLRAGPEAEARGGALAEDEPAAAHLLPSPYSKITPPRRP
HRCSSGHGSDNSSVLSGELPPAMGKTALFYHSGGSSGYESVMRDSEATGSASSAQDSTSE
NSSSVGGRCRSLKTPKKRSNPGSQRRRLIPALSLDTSSPVRKPPNSTGVRWVDGPLRSSP
RGLGEPFEIKVYEIDDVERLQRRRGGASKEAMCFNAKLKILEHRQQRIAEVRAKYEWLMK
ELEATKQYLMLDPNKWLSEFDLEQVWELDSLEYLEALECVTERLESRVNFCKAHLMMITC
FDITSRRR

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q52KG5	0.215	0.238	0.000	1881	0.407	0.456	Q52KG5.pdb.gz	KI26A_MOUSE Kinesin-like protein KIF26A OS=Mus musculus OX=10090 GN=Kif26a PE=1 SV=2
2	AFDB:Q7TNC6	0.215	0.215	0.000	2112	0.882	0.881	Q7TNC6.pdb.gz	KI26B_MOUSE Kinesin-like protein KIF26B OS=Mus musculus OX=10090 GN=Kif26b PE=1 SV=3
3	AFDB:Q9ULI4	0.219	0.241	0.000	1882	0.407	0.455	Q9ULI4.pdb.gz	KI26A_HUMAN Kinesin-like protein KIF26A OS=Homo sapiens OX=9606 GN=KIF26A PE=1 SV=3
4	PDB:7wrgA	0.139	0.345	8.093E-21	812	0.045	0.116	7wrgA.pdb.gz	The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
5	PDB:4h1gA	0.129	0.374	1.802E-18	670	0.046	0.146	4h1gA.pdb.gz	Crystal structure of the Candida albicans Kar3 kinesin motor domain fused to maltose-binding protein.
6	PDB:7wrgB	0.136	0.352	9.962E-18	783	0.043	0.115	7wrgB.pdb.gz	The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition.
7	AFDB:Q9NQT8	0.143	0.164	4.270E-12	1826	0.050	0.058	Q9NQT8.pdb.gz	KI13B_HUMAN Kinesin-like protein KIF13B OS=Homo sapiens OX=9606 GN=KIF13B PE=1 SV=2
8	AFDB:A0A0G2K8Z9	0.143	0.163	9.242E-12	1843	0.050	0.057	A0A0G2K8Z9.pdb.gz	A0A0G2K8Z9_RAT Kinesin family member 13B OS=Rattus norvegicus OX=10116 GN=Kif13b PE=1 SV=2
9	AFDB:Q57TT0	0.119	0.137	1.077E-8	1819	0.096	0.111	Q57TT0.pdb.gz	Q57TT0_TRYB2 Kinesin, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb08.30K1.750 PE=3 SV=1
10	AFDB:Q586D9	0.112	0.114	7.843E-8	2060	0.085	0.087	Q586D9.pdb.gz	Q586D9_TRYB2 Uncharacterized protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=1F7.170 PE=4 SV=1
11	AFDB:Q8T145	0.041	0.045	6.037E-7	1789	0.104	0.123	Q8T145.pdb.gz	Q8T145_DICDI DNA helicase OS=Dictyostelium discoideum OX=44689 GN=DDB_G0274841 PE=3 SV=2
12	AFDB:Q8MSX1	0.032	0.035	4.911E-6	1818	0.136	0.157	Q8MSX1.pdb.gz	ENC_DROME Protein encore OS=Drosophila melanogaster OX=7227 GN=enc PE=1 SV=2
13	AFDB:M9PGC5	0.040	0.036	3.203E-5	2462	0.141	0.121	M9PGC5.pdb.gz	WNK_DROME Serine/threonine-protein kinase Wnk OS=Drosophila melanogaster OX=7227 GN=Wnk PE=1 SV=2
14	PDB:6krwA	0.026	0.114	2.557E-1	306	0.007	0.046	6krwA.pdb.gz
15	PDB:4fdgB	0.022	0.051	6.902E-1	592	0.004	0.014	4fdgB.pdb.gz	Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.
16	PDB:1w4tA	0.030	0.112	9.094E-1	277	0.010	0.079	1w4tA.pdb.gz
17	PDB:5w3sA	0.028	0.078	1.073	485	0.012	0.054	5w3sA.pdb.gz	Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3.
18	PDB:6xtx3	0.021	0.050	1.134	608	0.007	0.025	6xtx3.pdb.gz	CryoEM structures of human CMG-ATP gamma S-DNA and CMG-AND-1 complexes.
19	PDB:6skl3	0.021	0.049	1.414	616	0.008	0.028	6skl3.pdb.gz	Cryo-EM Structure of the Fork Protection Complex Bound to CMG at a Replication Fork.
20	PDB:1p1fA	0.028	0.088	1.494	501	0.009	0.038	1p1fA.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q52KG5	0.0	801	1881	0.219	0.246	KI26A_MOUSE Kinesin-like protein KIF26A OS=Mus musculus OX=10090 GN=Kif26a PE=1 SV=2
2	Q7TNC6	0.0	3440	2112	0.883	0.881	KI26B_MOUSE Kinesin-like protein KIF26B OS=Mus musculus OX=10090 GN=Kif26b PE=1 SV=3
3	Q9ULI4	0.0	780	1882	0.227	0.254	KI26A_HUMAN Kinesin-like protein KIF26A OS=Homo sapiens OX=9606 GN=KIF26A PE=1 SV=3
4	Q9VRK9	1.69e-35	148	677	0.055	0.171	Q9VRK9_DROME Kinesin-like protein OS=Drosophila melanogaster OX=7227 GN=Klp64D PE=3 SV=1
5	P46872	4.10e-34	144	699	0.052	0.157	KRP85_STRPU Kinesin-II 85 kDa subunit OS=Strongylocentrotus purpuratus OX=7668 GN=KRP85 PE=1 SV=1
6	F1QN54	1.02e-33	143	775	0.046	0.126	KIF3B_DANRE Kinesin-like protein KIF3B OS=Danio rerio OX=7955 GN=kif3b PE=2 SV=1
7	F1LQZ3	1.17e-33	143	726	0.050	0.146	F1LQZ3_RAT Kinesin-like protein OS=Rattus norvegicus OX=10116 GN=Kif3a PE=1 SV=3
8	Q61771	2.21e-33	142	747	0.047	0.133	KIF3B_MOUSE Kinesin-like protein KIF3B OS=Mus musculus OX=10090 GN=Kif3b PE=1 SV=1
9	O15066	3.51e-33	141	747	0.047	0.133	KIF3B_HUMAN Kinesin-like protein KIF3B OS=Homo sapiens OX=9606 GN=KIF3B PE=1 SV=1
10	D3ZI07	4.11e-33	141	747	0.046	0.131	D3ZI07_RAT Kinesin-like protein OS=Rattus norvegicus OX=10116 GN=Kif3b PE=3 SV=1
11	P46869	5.00e-33	141	786	0.049	0.132	FLA10_CHLRE Kinesin-like protein FLA10 OS=Chlamydomonas reinhardtii OX=3055 GN=FLA10 PE=1 SV=1
12	Q9P2E2	1.44e-32	140	1029	0.047	0.096	KIF17_HUMAN Kinesin-like protein KIF17 OS=Homo sapiens OX=9606 GN=KIF17 PE=2 SV=3
13	Q99PW8	3.77e-32	139	1038	0.054	0.109	KIF17_MOUSE Kinesin-like protein KIF17 OS=Mus musculus OX=10090 GN=Kif17 PE=1 SV=1
14	O14782	6.10e-32	138	793	0.056	0.149	KIF3C_HUMAN Kinesin-like protein KIF3C OS=Homo sapiens OX=9606 GN=KIF3C PE=1 SV=4
15	Q965T6	6.62e-32	137	646	0.048	0.158	KLP20_CAEEL Kinesin-like protein klp-20 OS=Caenorhabditis elegans OX=6239 GN=klp-20 PE=1 SV=1
16	Q9Y496	1.14e-31	136	699	0.056	0.170	KIF3A_HUMAN Kinesin-like protein KIF3A OS=Homo sapiens OX=9606 GN=KIF3A PE=1 SV=4
17	Q498L9	1.15e-31	138	1387	0.052	0.079	KI15B_XENLA Kinesin-like protein KIF15-B OS=Xenopus laevis OX=8355 GN=kif15-b PE=1 SV=1
18	F1QV34	1.77e-31	137	823	0.047	0.120	F1QV34_DANRE Kinesin-like protein OS=Danio rerio OX=7955 GN=kif17 PE=3 SV=1
19	A0A8I6GCQ1	2.45e-31	135	674	0.050	0.157	A0A8I6GCQ1_RAT Kinesin-like protein OS=Rattus norvegicus OX=10116 GN=Kif3a PE=3 SV=1
20	O35066	2.48e-31	136	796	0.056	0.147	KIF3C_MOUSE Kinesin-like protein KIF3C OS=Mus musculus OX=10090 GN=Kif3c PE=1 SV=3

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00225 Kinesin	2.1e-55	199.6	Kinesin motor domain
2	PF16796 Microtub_bd	7.9e-11	53.6	Microtubule binding

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000385545

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000353590	0.826	Myosin-10
2	9606.ENSP00000354560	0.705	Kinesin-associated protein 3
3	9606.ENSP00000291231	0.698	Olfactory receptor 3A3
4	9606.ENSP00000334563	0.690	Unconventional myosin-XVIIIb
5	9606.ENSP00000386213	0.688	Myosin-IIIb
6	9606.ENSP00000319197	0.684	Olfactory receptor 4K17
7	9606.ENSP00000386180	0.673	Olfactory receptor 3A2
8	9606.ENSP00000361883	0.659	Adenylyl cyclase-associated protein 1
9	9606.ENSP00000260363	0.653	Kinesin-like protein KIF23
10	9606.ENSP00000378356	0.641	Kinesin-like protein KIF20A
11	9606.ENSP00000399403	0.640	Kinesin light chain 2
12	9606.ENSP00000414982	0.627	Kinesin light chain 1
13	9606.ENSP00000359292	0.623	SMC5-SMC6 complex localization factor protein 2
14	9606.ENSP00000404190	0.610	Rac GTPase-activating protein 1
15	9606.ENSP00000260731	0.606	Kinesin-like protein KIF11
16	9606.ENSP00000263181	0.603	Kinesin-like protein KIF18A
17	9606.ENSP00000025301	0.598	A-kinase anchor protein 11
18	9606.ENSP00000375810	0.597	Kinesin light chain 3
19	9606.ENSP00000278193	0.594	Protein lin-7 homolog C
20	9606.ENSP00000231130	0.593	Protocadherin beta-3

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	0.999	protein binding
GO:0008092	0.880	cytoskeletal protein binding
GO:0015631	0.684	tubulin binding
GO:0003774	0.670	cytoskeletal motor activity
GO:0008017	0.621	microtubule binding
GO:0003777	0.411	microtubule motor activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.989	cellular process
GO:0050794	0.986	regulation of cellular process
GO:0048856	0.966	anatomical structure development
GO:0032501	0.957	multicellular organismal process
GO:0007275	0.948	multicellular organism development
GO:0048731	0.943	system development
GO:0001822	0.876	kidney development
GO:0009888	0.874	tissue development
GO:0072073	0.851	kidney epithelium development
GO:0035239	0.849	tube morphogenesis
GO:0009887	0.843	animal organ morphogenesis
GO:0048522	0.724	positive regulation of cellular process
GO:0060993	0.694	kidney morphogenesis
GO:0001823	0.693	mesonephros development
GO:0072028	0.677	nephron morphogenesis
GO:0072164	0.676	mesonephric tubule development
GO:0072080	0.676	nephron tubule development
GO:0061333	0.676	renal tubule morphogenesis
GO:0072171	0.647	mesonephric tubule morphogenesis
GO:0071840	0.424	cellular component organization or biogenesis
GO:0016043	0.389	cellular component organization

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005737	1.000	cytoplasm
GO:0043229	0.997	intracellular organelle
GO:0043227	0.980	membrane-bounded organelle
GO:0043232	0.971	intracellular non-membrane-bounded organelle
GO:0005829	0.954	cytosol
GO:0043231	0.954	intracellular membrane-bounded organelle
GO:0005856	0.886	cytoskeleton
GO:0016020	0.847	membrane
GO:0005634	0.843	nucleus
GO:0032991	0.817	protein-containing complex
GO:0015630	0.586	microtubule cytoskeleton
GO:0099081	0.316	supramolecular polymer

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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