StarFunc result for job id Q4AE62

User Input

>input (458 residues)
MSILIIEAFYGGSHKQLVDLLQEELGDCVVYTLPAKKWHWRARTSALYFSQTIPISEHYR
TLFASSVLNLTELAALRPDLGKLKKILYFHENQLIYPVKKCQERDFQYGYNQILSCLVAD
VVVFNSVFNMESFLTSMGKFMKLIPDHRPKDLESIIRPKCQVIYFPIRFPDVSRFMPKHK
TTHLKKMLGLKGNGGAVLSMALPFQPEQRDSEDLLKNFNSECDTHCGLDTARQEYLGNSL
RQESDLKKSTSSDNSSSHHGENKQNLTVDPCDILGGVDNQQRLLHIVWPHRWEHDKDPES
FFKVLMHLKDLGLNFHVSVLGETFTDVPDIFSEAKKALGSSVLHWGYLPSKDDYFQVLCM
ADVVISTAKHEFFGVAMLEAVYCGCYPLCPKDLVYPEIFPAEYLYSTPEQLSKRLQNFCK
RPDIIRKHLYKGEIAPFSWAALHGKFRSLLTTEPREDL

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q568B7	0.788	0.833	2.683E-61	433	0.592	0.626	Q568B7.pdb.gz	GTDC1_DANRE Glycosyltransferase-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=gtdc1 PE=2 SV=2
2	PDB:3okaA	0.542	0.641	1.609E-9	378	0.172	0.209	3okaA.pdb.gz	Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: structural and mutational analysis of mannosyltransferase Corynebacterium glutamicum PimB'.
3	PDB:5hutA	0.526	0.516	1.908E-9	469	0.122	0.119	5hutA.pdb.gz	Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
4	PDB:5hvmB	0.544	0.551	1.852E-8	452	0.116	0.117	5hvmB.pdb.gz	Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
5	PDB:2iv7A	0.528	0.639	1.699E-7	370	0.127	0.157	2iv7A.pdb.gz	Insights Into the Synthesis of Lipopolysaccharide and Antibiotics Through the Structures of Two Retaining Glycosyltransferases from Family Gt4
6	PDB:5hvoA	0.522	0.521	2.833E-7	459	0.144	0.144	5hvoA.pdb.gz	Structural and In Vivo Studies on Trehalose-6-Phosphate Synthase from Pathogenic Fungi Provide Insights into Its Catalytic Mechanism, Biological Necessity, and Potential for Novel Antifungal Drug Design.
7	PDB:2wtxD	0.562	0.563	4.463E-7	457	0.109	0.109	2wtxD.pdb.gz	Mechanistic Insight Into Enzymatic Glycosyl Transfer with Retention of Configuration Through Analysis of Glycomimetic Inhibitors.
8	PDB:3guhA	0.544	0.525	4.463E-7	477	0.144	0.138	3guhA.pdb.gz	The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase.
9	AFDB:Q8S4F6	0.538	0.490	5.210E-7	510	0.124	0.112	Q8S4F6.pdb.gz	SQD2_ARATH Sulfoquinovosyl transferase SQD2 OS=Arabidopsis thaliana OX=3702 GN=SQD2 PE=1 SV=1
10	PDB:7q0bB	0.444	0.344	6.092E-6	623	0.144	0.106	7q0bB.pdb.gz
11	AFDB:A2Y8X2	0.445	0.350	8.926E-6	609	0.120	0.090	A2Y8X2.pdb.gz	SSG1_ORYSI Granule-bound starch synthase 1, chloroplastic/amyloplastic OS=Oryza sativa subsp. indica OX=39946 GN=WAXY PE=1 SV=2
12	PDB:1pswA	0.305	0.388	1.016E-5	331	0.090	0.124	1pswA.pdb.gz
13	PDB:3s27H	0.520	0.323	1.016E-5	797	0.151	0.087	3s27H.pdb.gz	The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
14	AFDB:Q0DEC8	0.467	0.350	1.058E-5	641	0.129	0.092	Q0DEC8.pdb.gz	SSY1_ORYSJ Soluble starch synthase 1, chloroplastic/amyloplastic OS=Oryza sativa subsp. japonica OX=39947 GN=SS1 PE=1 SV=1
15	AFDB:Q9MAC8	0.518	0.324	7.733E-5	792	0.146	0.085	Q9MAC8.pdb.gz	SSY2_ARATH Starch synthase 2, chloroplastic/amyloplastic OS=Arabidopsis thaliana OX=3702 GN=SS2 PE=1 SV=1
16	AFDB:O53493	0.133	0.075	1.025E-2	874	0.098	0.051	O53493.pdb.gz	PPMNT_MYCTU Bifunctional apolipoprotein N-acyltransferase/polyprenol monophosphomannose synthase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=ppm1 PE=1 SV=1
17	AFDB:G0SB31	0.157	0.100	3.379E-2	765	0.072	0.043	G0SB31.pdb.gz	SKN7_CHATD Transcription factor SKN7 OS=Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) OX=759272 GN=SKN7 PE=1 SV=1
18	AFDB:P41911	0.116	0.119	3.785E-2	440	0.050	0.052	P41911.pdb.gz	GPD2_YEAST Glycerol-3-phosphate dehydrogenase [NAD(+)] 2, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=GPD2 PE=1 SV=2
19	AFDB:C8V7M0	0.165	0.138	5.029E-2	558	0.061	0.050	C8V7M0.pdb.gz	C8V7M0_EMENI Transcription factor OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=srrA PE=4 SV=1
20	AFDB:Q75L84	0.101	0.119	6.312E-2	371	0.063	0.078	Q75L84.pdb.gz	GT43A_ORYSJ Probable beta-1,4-xylosyltransferase GT43A OS=Oryza sativa subsp. japonica OX=39947 GN=GT43A PE=2 SV=1

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q568B7	0.0	543	433	0.590	0.624	GTDC1_DANRE Glycosyltransferase-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=gtdc1 PE=2 SV=2
2	P0CF99	9.73e-06	50.1	381	0.079	0.094	PIMC_MYCTO GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol dimannoside mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pimC PE=1 SV=1
3	P32363	0.11	37.4	452	0.046	0.046	GPI3_YEAST Phosphatidylinositol N-acetylglucosaminyltransferase GPI3 subunit OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=SPT14 PE=1 SV=4
4	Q6XHA7	0.41	35.8	3365	0.063	0.009	ROCO9_DICDI Probable serine/threonine-protein kinase roco9 OS=Dictyostelium discoideum OX=44689 GN=roco9 PE=3 SV=1
5	Q65CC1	1.3	33.9	387	0.052	0.062	KANF_STRKN 2-deoxystreptamine glucosyltransferase OS=Streptomyces kanamyceticus OX=1967 GN=kanF PE=1 SV=1
6	Q94AA9	2.5	33.1	500	0.037	0.034	XGD1_ARATH Xylogalacturonan beta-1,3-xylosyltransferase OS=Arabidopsis thaliana OX=3702 GN=XGD1 PE=1 SV=2
7	Q9Y4D1	2.7	33.1	1078	0.039	0.017	DAAM1_HUMAN Disheveled-associated activator of morphogenesis 1 OS=Homo sapiens OX=9606 GN=DAAM1 PE=1 SV=2
8	Q8WXF0	3.2	32.3	261	0.052	0.092	SRS12_HUMAN Serine/arginine-rich splicing factor 12 OS=Homo sapiens OX=9606 GN=SRSF12 PE=2 SV=1
9	M9MS86	3.8	32.7	1144	0.033	0.013	M9MS86_DROME Mucin related 2B, isoform B OS=Drosophila melanogaster OX=7227 GN=Mur2B PE=4 SV=1
10	F6ZDS4	5.5	32.3	2431	0.031	0.006	TPR_MOUSE Nucleoprotein TPR OS=Mus musculus OX=10090 GN=Tpr PE=1 SV=1
11	A0A0R4IER9	5.6	32.0	1060	0.028	0.012	A0A0R4IER9_DANRE Disheveled-associated activator of morphogenesis 1 isoform X2 OS=Danio rerio OX=7955 GN=daam1a PE=4 SV=1
12	Q5EE04	6.3	32.0	1997	0.035	0.008	TPR_XENLA Nucleoprotein TPR (Fragment) OS=Xenopus laevis OX=8355 GN=tpr PE=1 SV=1
13	P12270	6.8	32.0	2363	0.031	0.006	TPR_HUMAN Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3
14	F1MA98	7.2	32.0	2360	0.031	0.006	TPR_RAT Nucleoprotein TPR OS=Rattus norvegicus OX=10116 GN=Tpr PE=1 SV=1
15	O76894	7.2	31.6	1795	0.033	0.008	O76894_DROME EG:56G7.1 protein OS=Drosophila melanogaster OX=7227 GN=Mur2B PE=4 SV=2
16	Q5AI14	8.8	31.6	888	0.044	0.023	Q5AI14_CANAL Trehalose-phosphatase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=TPS2 PE=1 SV=1
17	Q8BPM0	9.1	31.2	1077	0.035	0.015	DAAM1_MOUSE Disheveled-associated activator of morphogenesis 1 OS=Mus musculus OX=10090 GN=Daam1 PE=1 SV=4
18	Q4GZ50	9.3	31.2	817	0.041	0.023	Q4GZ50_TRYB2 RNA-editing complex protein nuclease, putative KREPB1 OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=KREPB1 PE=4 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF12038 DUF3524	3.4e-65	230.4	Domain of unknown function (DUF3524)
2	PF00534 Glycos_transf_1	0.00039	31.5	Glycosyl transferases group 1
3	PF13524 Glyco_trans_1_2	5.2e+02	12.5	Glycosyl transferases group 1

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000376608

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000362381	0.759	Torsin-2A
2	9606.ENSP00000295095	0.657	Rho GTPase-activating protein 15
3	9606.ENSP00000264170	0.634	Kynureninase
4	9606.ENSP00000280987	0.631	Protein FAM177A1
5	9606.ENSP00000343617	0.570	Zinc finger protein 606
6	9606.ENSP00000369853	0.563	C2 calcium dependent domain containing 2
7	9606.ENSP00000338572	0.536	Zinc finger protein 212
8	9606.ENSP00000280098	0.535	Speckle-type POZ protein-like
9	9606.ENSP00000391088	0.519	Protein unc-80 homolog
10	9606.ENSP00000359305	0.508	Transmembrane emp24 domain-containing protein 5

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0016758	1.000	hexosyltransferase activity
GO:0005488	0.996	binding
GO:0005515	0.950	protein binding
GO:0046527	0.607	glucosyltransferase activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.751	cellular process
GO:0008152	0.590	metabolic process
GO:0071704	0.537	organic substance metabolic process
GO:0044238	0.516	primary metabolic process
GO:0032501	0.512	multicellular organismal process
GO:0032502	0.445	developmental process
GO:0044237	0.434	cellular metabolic process
GO:0048856	0.401	anatomical structure development
GO:0006807	0.390	nitrogen compound metabolic process
GO:0007275	0.385	multicellular organism development
GO:1901564	0.324	organonitrogen compound metabolic process
GO:0043170	0.305	macromolecule metabolic process
GO:0007417	0.302	central nervous system development

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005737	1.000	cytoplasm
GO:0043231	0.998	intracellular membrane-bounded organelle
GO:0005634	0.938	nucleus
GO:0005829	0.923	cytosol
GO:0012505	0.554	endomembrane system
GO:0016020	0.386	membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name
EC:2.4.1.-	1.000	Hexosyltransferases.

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