StarFunc result for job id Q6L9W6

User Input

>input (998 residues)
MGSPRAARPPLLLRPVKLLRRRFRLLLALAVVSVGLWTLYLELVASAQVGGNPLNRRYGS
WRELAKALASRNIPAVDPHLQFYHPQRLSLEDHDIDQGVSSNSSYLKWNKPVPWLSEFRG
RANLHVFEDWCGSSIQQLRRNLHFPLYPHIRTTLRKLAVSPKWTNYGLRIFGYLHPFTDG
KIQFAIAADDNAEFWLSLDDQVSGLQLLASVGKTGKEWTAPGEFGKFRSQISKPVSLSAS
HRYYFEVLHKQNEEGTDHVEVAWRRNDPGAKFTIIDSLSLSLFTNETFLQMDEVGHIPQT
AASHVDSSNALPRDEQPPADMLRPDPRDTLYRVPLIPKSHLRHVLPDCPYKPSYLVDGLP
LQRYQGLRFVHLSFVYPNDYTRLSHMETHNKCFYQENAYYQDRFSFQEYIKIDQPEKQGL
EQPGFEENLLEESQYGEVAEETPASNNQNARMLEGRQTPASTLEQDATDYRLRSLRKLLA
QPREGLLAPFSKRNSTASFPGRTSHIPVQQPEKRKQKPSPEPSQDSPHSDKWPPGHPVKN
LPQMRGPRPRPAGDSPRKTQWLNQVESYIAEQRRGDRMRPQAPGRGWHGEEEVVAAAGQE
GQVEGEEEGEEEEEEEDMSEVFEYVPVFDPVVNWDQTFSARNLDFQALRTDWIDLSCNTS
GNLLLPEQEALEVTRVFLKKLNQRSRGRYQLQRIVNVEKRQDQLRGGRYLLELELLEQGQ
RVVRLSEYVSARGWQGIDPAGGEEVEARNLQGLVWDPHNRRRQVLNTRAQEPKLCWPQGF
SWSHRAVVHFVVPVKNQARWVQQFIKDMENLFQVTGDPHFNIVITDYSSEDMDVEMALKR
SKLRSYQYVKLSGNFERSAGLQAGIDLVKDPHSIIFLCDLHIHFPAGVIDAIRKHCVEGK
MAFAPMVMRLHCGATPQWPEGYWEVNGFGLLGIYKSDLDRIGGMNTKEFRDRWGGEDWEL
LDRILQAGLDVERLSLRNFFHHFHSKRGMWSRRQMKTL

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q6L9W6	1.000	1.000	0.000	998	1.000	1.000	Q6L9W6.pdb.gz	B4GN3_HUMAN Beta-1,4-N-acetylgalactosaminyltransferase 3 OS=Homo sapiens OX=9606 GN=B4GALNT3 PE=1 SV=2
2	AFDB:Q76KP1	0.642	0.617	0.000	1039	0.472	0.453	Q76KP1.pdb.gz	B4GN4_HUMAN N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALNT4 PE=1 SV=1
3	AFDB:Q6FX55	0.132	0.178	4.989E-7	715	0.074	0.103	Q6FX55.pdb.gz	Q6FX55_CANGA Candida glabrata strain CBS138 chromosome C complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=EPA6 PE=1 SV=1
4	PDB:4d11C	0.157	0.334	9.147E-7	436	0.046	0.106	4d11C.pdb.gz	Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N- Acetylgalactosaminyltransferase 2.
5	PDB:6h0bB	0.171	0.315	2.099E-6	521	0.042	0.081	6h0bB.pdb.gz	Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4.
6	PDB:6pxuB	0.170	0.306	2.099E-6	532	0.039	0.073	6pxuB.pdb.gz	The structure of the colorectal cancer-associated enzyme GalNAc-T12 reveals how nonconserved residues dictate its function.
7	PDB:4d0tA	0.166	0.320	2.219E-6	496	0.048	0.097	4d0tA.pdb.gz	Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N-Acetylgalactosaminyltransferase 2.
8	PDB:1t6bX	0.112	0.162	9.363E-6	676	0.027	0.040	1t6bX.pdb.gz	Crystal structure of a complex between anthrax toxin and its host cell receptor
9	PDB:2d7iA	0.174	0.309	1.235E-5	536	0.034	0.063	2d7iA.pdb.gz	Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10)
10	AFDB:Q6FUW5	0.126	0.122	1.309E-5	1034	0.064	0.062	Q6FUW5.pdb.gz	Q6FUW5_CANGA Candida glabrata strain CBS138 chromosome E complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=EPA1 PE=1 SV=1
11	PDB:4h2aA	0.112	0.155	3.537E-5	704	0.031	0.044	4h2aA.pdb.gz	Crystal structure of wild type protective antigen to 1.62 A (pH 7.5)
12	PDB:5mlzA	0.143	0.359	5.211E-5	355	0.039	0.110	5mlzA.pdb.gz	Structural basis for dolichylphosphate mannose biosynthesis.
13	PDB:4fixA	0.155	0.234	6.153E-5	629	0.036	0.057	4fixA.pdb.gz	Tetrameric Structure of the GlfT2 Galactofuranosyltransferase Reveals a Scaffold for the Assembly of Mycobacterial Arabinogalactan.
14	PDB:6iwqA	0.163	0.283	2.745E-4	546	0.039	0.071	6iwqA.pdb.gz	Structural basis of carbohydrate transfer activity of UDP-GalNAc: Polypeptide N-acetylgalactosaminyltransferase 7.
15	AFDB:Q99NE5	0.051	0.038	7.635E-3	1463	0.087	0.059	Q99NE5.pdb.gz	RIMS1_MOUSE Regulating synaptic membrane exocytosis protein 1 OS=Mus musculus OX=10090 GN=Rims1 PE=1 SV=2
16	AFDB:P42835	0.073	0.070	1.658E-2	1041	0.051	0.049	P42835.pdb.gz	EGT2_YEAST Protein EGT2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=EGT2 PE=2 SV=2
17	AFDB:Q9ULM3	0.054	0.042	3.599E-2	1422	0.079	0.056	Q9ULM3.pdb.gz	YETS2_HUMAN YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2
18	AFDB:Q3TUF7	0.055	0.042	3.804E-2	1407	0.083	0.059	Q3TUF7.pdb.gz	YETS2_MOUSE YEATS domain-containing protein 2 OS=Mus musculus OX=10090 GN=Yeats2 PE=1 SV=2
19	AFDB:Q7ZTU9	0.064	0.083	3.804E-2	687	0.077	0.112	Q7ZTU9.pdb.gz	TBX2_DANRE T-box transcription factor TBX2b OS=Danio rerio OX=7955 GN=tbx2b PE=1 SV=4
20	AFDB:Q99MR9	0.044	0.042	5.018E-2	1089	0.087	0.080	Q99MR9.pdb.gz	PPR3A_MOUSE Protein phosphatase 1 regulatory subunit 3A OS=Mus musculus OX=10090 GN=Ppp1r3a PE=1 SV=2

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	E9PHD9	0.0	1175	636	0.571	0.896	E9PHD9_HUMAN Beta-1,4-N-acetyl-galactosaminyltransferase 3 (Fragment) OS=Homo sapiens OX=9606 GN=B4GALNT3 PE=1 SV=8
2	Q6L9W6	0.0	2063	998	1.000	1.000	B4GN3_HUMAN Beta-1,4-N-acetylgalactosaminyltransferase 3 OS=Homo sapiens OX=9606 GN=B4GALNT3 PE=1 SV=2
3	Q76KP1	6.07e-142	452	1039	0.221	0.213	B4GN4_HUMAN N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=B4GALNT4 PE=1 SV=1
4	Q8TDX6	1.00e-19	96.3	532	0.058	0.109	CGAT1_HUMAN Chondroitin sulfate N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=CSGALNACT1 PE=1 SV=2
5	Q8BJQ9	3.90e-19	94.7	530	0.063	0.119	CGAT1_MOUSE Chondroitin sulfate N-acetylgalactosaminyltransferase 1 OS=Mus musculus OX=10090 GN=Csgalnact1 PE=2 SV=1
6	Q8N6G5	9.20e-17	87.0	542	0.058	0.107	CGAT2_HUMAN Chondroitin sulfate N-acetylgalactosaminyltransferase 2 OS=Homo sapiens OX=9606 GN=CSGALNACT2 PE=1 SV=1
7	Q8C1F4	1.21e-15	83.6	542	0.056	0.103	CGAT2_MOUSE Chondroitin sulfate N-acetylgalactosaminyltransferase 2 OS=Mus musculus OX=10090 GN=Csgalnact2 PE=2 SV=1
8	E7F6G2	4.72e-15	82.0	580	0.057	0.098	E7F6G2_DANRE Hexosyltransferase OS=Danio rerio OX=7955 GN=csgalnact1a PE=3 SV=1
9	Q6ZQ11	1.99e-14	80.5	800	0.081	0.101	CHSS1_MOUSE Chondroitin sulfate synthase 1 OS=Mus musculus OX=10090 GN=Chsy1 PE=2 SV=2
10	D3ZRM3	3.46e-14	79.7	799	0.080	0.100	D3ZRM3_RAT Hexosyltransferase OS=Rattus norvegicus OX=10116 GN=Chsy1 PE=3 SV=3
11	Q86X52	2.26e-13	77.0	802	0.076	0.095	CHSS1_HUMAN Chondroitin sulfate synthase 1 OS=Homo sapiens OX=9606 GN=CHSY1 PE=1 SV=3
12	Q5DTK1	3.23e-11	70.1	884	0.078	0.088	CHSS3_MOUSE Chondroitin sulfate synthase 3 OS=Mus musculus OX=10090 GN=Chsy3 PE=2 SV=3
13	Q70JA7	3.73e-11	69.7	882	0.076	0.086	CHSS3_HUMAN Chondroitin sulfate synthase 3 OS=Homo sapiens OX=9606 GN=CHSY3 PE=2 SV=3
14	Q6P296	4.62e-11	69.3	801	0.080	0.100	Q6P296_DANRE Hexosyltransferase OS=Danio rerio OX=7955 GN=chys1 PE=2 SV=1
15	A1Z863	6.78e-11	68.6	540	0.045	0.083	A1Z863_DROME Hexosyltransferase OS=Drosophila melanogaster OX=7227 GN=Csgalnact PE=2 SV=1
16	Q7Z1Z1	2.56e-08	60.5	736	0.052	0.071	CHSSA_CAEEL Chondroitin sulfate synthase sqv-5 OS=Caenorhabditis elegans OX=6239 GN=sqv-5 PE=1 SV=1
17	A0A0S2Z5K4	2.45e-04	47.0	416	0.024	0.058	A0A0S2Z5K4_HUMAN Hexosyltransferase OS=Homo sapiens OX=9606 GN=CSGALNACT2 PE=1 SV=1
18	F2X2F1	0.24	36.6	188	0.019	0.101	F2X2F1_BOVIN Insulin-like growth factor I OS=Bos taurus OX=9913 GN=IGF1 PE=2 SV=1
19	F2X2F3	0.32	35.8	172	0.019	0.110	F2X2F3_BOVIN Insulin-like growth factor I OS=Bos taurus OX=9913 GN=IGF1 PE=2 SV=1
20	Q381T9	0.57	36.6	704	0.033	0.047	Q381T9_TRYB2 PUM-HD domain-containing protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.01.6600 PE=4 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF05679 CHGN	3e-22	90.8	Chondroitin N-acetylgalactosaminyltransferase
2	PF02709 Glyco_transf_7C	1.2e-09	49.1	N-terminal domain of galactosyltransferase
3	PF07691 PA14	0.0079	27.5	PA14 domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000266383

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000353910	0.931	Alpha-(1,6)-fucosyltransferase
2	9606.ENSP00000480428	0.927	Beta-1,4-galactosyltransferase 3
3	9606.ENSP00000369055	0.925	Beta-1,4-galactosyltransferase 1
4	9606.ENSP00000262622	0.916	Carbohydrate sulfotransferase 8
5	9606.ENSP00000480991	0.915	Carbohydrate sulfotransferase 9
6	9606.ENSP00000310696	0.910	Beta-1,4-galactosyltransferase 2
7	9606.ENSP00000328277	0.816	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1
8	9606.ENSP00000300404	0.706	Beta-1,4 N-acetylgalactosaminyltransferase 2
9	9606.ENSP00000341562	0.606	Beta-1,4 N-acetylgalactosaminyltransferase 1
10	9606.ENSP00000482600	0.552	Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7
11	9606.ENSP00000269195	0.538	Polypeptide N-acetylgalactosaminyltransferase 1
12	9606.ENSP00000386377	0.538	Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A
13	9606.ENSP00000321874	0.530	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
14	9606.ENSP00000329548	0.509	Tumor suppressor candidate 5

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0008376	1.000	acetylgalactosaminyltransferase activity
GO:0005488	0.841	binding
GO:0005515	0.692	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0009100	0.995	glycoprotein metabolic process
GO:0044249	0.972	cellular biosynthetic process
GO:1901137	0.969	carbohydrate derivative biosynthetic process
GO:1901566	0.968	organonitrogen compound biosynthetic process
GO:0009059	0.916	macromolecule biosynthetic process
GO:0034645	0.906	cellular macromolecule biosynthetic process
GO:0009101	0.898	glycoprotein biosynthetic process
GO:0006790	0.443	sulfur compound metabolic process
GO:0006022	0.367	aminoglycan metabolic process
GO:0006029	0.362	proteoglycan metabolic process
GO:0030203	0.326	glycosaminoglycan metabolic process
GO:0050654	0.313	chondroitin sulfate proteoglycan metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005794	1.000	Golgi apparatus
GO:0016020	0.745	membrane
GO:0031090	0.442	organelle membrane
GO:0000139	0.421	Golgi membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name
EC:2.4.1.-	1.000	Hexosyltransferases.

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