StarFunc result for job id Q6UB99

User Input

>input (2663 residues)
MPKGGCPKAPQQEELPLSSDMVEKQTGKKDKDKVSLTKTPKLERGDGGKEVRERASKRKL
PFTAGANGEQKDSDTEKQGPERKRIKKEPVTRKAGLLFGMGLSGIRAGYPLSERQQVALL
MQMTAEESANSPVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRLHRAAIRGD
ARRIKELISEGADVNVKDFAGWTALHEACNRGYYDVAKQLLAAGAEVNTKGLDDDTPLHD
AANNGHYKVVKLLLRYGGNPQQSNRKGETPLKVANSPTMVNLLLGKGTYTSSEESSTESS
EEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDEYEFDEDDEQDRVPP
VDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKASHRILSDTSDEEDASVTV
GTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRSDKFCSSE
SESESSESGEDDRDSLGSSGCLKGSPLVLKDPSLFSSLSASSTSSHGSSAAQKQNPSHTD
QHTKHWRTDNWKTISSPAWSEVSSLSDSTRTRLTSESDYSSEGSSVESLKPVRKRQEHRK
RASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYE
YEDSKQKSDKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKR
IKDTNKDISRSFREEKDRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKN
DLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDR
WFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRDY
REPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKE
RRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKERK
EKTKPERYKEKSSDKDKSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKASL
DQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESEDDRDSCMGSGFKMGEA
SDLPRTDGLQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAGRDKKEK
VFEKHKEKKDKESTEKYKDRKDRASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKS
DKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAF
LEVSFTEPPGDDKPRESACLPEKLKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDY
KEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKK
IEKELKPYGSSAINILKEKKKREKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQ
KPATRDKDSPPRVLKDKSRDEGPRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKD
PGKKDARPREKLLGDGDLMMTSFERMLSQKDLEIEERHKRHKERMKQMEKLRHRSGDPKL
KEKAKPADDGRKKGLDIPAKKPPGLDPPFKDKKLKESTPIPPAAENKLHPASGADSKDWL
AGPHMKEVLPASPRPDQSRPTGVPTPTSVLSCPSYEEVMHTPRTPSCSADDYADLVFDCA
DSQHSTPVPTAPTSACSPSFFDRFSVASSGLSENASQAPARPLSTNLYRSVSVDIRRTPE
EEFSVGDKLFRQQSVPAASSYDSPMPPSMEDRAPLPPVPAEKFACLSPGYYSPDYGLPSP
KVDALHCPPAAVVTVTPSPEGVFSSLQAKPSPSPRAELLVPSLEGALPPDLDTSEDQQAT
AAIIPPEPSYLEPLDEGPFSAVITEEPVEWAHPSEQALASSLIGGTSENPVSWPVGSDLL
LKSPQRFPESPKRFCPADPLHSAAPGPFSASEAPYPAPPASPAPYALPVAEPGLEDVKDG
VDAVPAAISTSEAAPYAPPSGLESFFSNCKSLPEAPLDVAPEPACVAAVAQVEALGPLEN
SFLDGSRGLSHLGQVEPVPWADAFAGPEDDLDLGPFSLPELPLQTKDAADGEAEPVEESL
APPEEMPPGAPGVINGGDVSTVVAEEPPALPPDQASTRLPAELEPEPSGEPKLDVALEAA
VEAETVPEERARGDPDSSVEPAPVPPEQRPLGSGDQGAEAEGPPAASLCAPDGPAPNTVA
QAQAADGAGPEDDTEASRAAAPAEGPPGGIQPEAAEPKPTAEAPKAPRVEEIPQRMTRNR
AQMLANQSKQGPPPSEKECAPTPAPVTRAKARGSEDDDAQAQHPRKRRFQRSTQQLQQQL
NTSTQQTREVIQQTLAAIVDAIKLDAIEPYHSDRANPYFEYLQIRKKIEEKRKILCCITP
QAPQCYAEYVTYTGSYLLDGKPLSKLHIPVIAPPPSLAEPLKELFRQQEAVRGKLRLQHS
IEREKLIVSCEQEILRVHCRAARTIANQAVPFSACTMLLDSEVYNMPLESQGDENKSVRD
RFNARQFISWLQDVDDKYDRMKTCLLMRQQHEAAALNAVQRMEWQLKVQELDPAGHKSLC
VNEVPSFYVPMVDVNDDFVLLPA

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:E9Q4F7	0.095	0.096	0.000	2643	0.797	0.803	E9Q4F7.pdb.gz	ANR11_MOUSE Ankyrin repeat domain-containing protein 11 OS=Mus musculus OX=10090 GN=Ankrd11 PE=1 SV=1
2	AFDB:Q6UB99	1.000	1.000	0.000	2663	1.000	1.000	Q6UB99.pdb.gz	ANR11_HUMAN Ankyrin repeat domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ANKRD11 PE=1 SV=3
3	AFDB:Q6UB98	0.096	0.115	3.851E-65	2062	0.296	0.383	Q6UB98.pdb.gz	ANR12_HUMAN Ankyrin repeat domain-containing protein 12 OS=Homo sapiens OX=9606 GN=ANKRD12 PE=1 SV=3
4	AFDB:A0A140LI88	0.048	0.068	7.806E-10	1857	0.072	0.103	A0A140LI88.pdb.gz	ANR31_MOUSE Ankyrin repeat domain-containing protein 31 OS=Mus musculus OX=10090 GN=Ankrd31 PE=1 SV=2
5	PDB:2dvwA	0.047	0.536	1.604E-9	229	0.016	0.183	2dvwA.pdb.gz
6	PDB:8cs9A	0.049	0.161	1.700E-9	796	0.018	0.060	8cs9A.pdb.gz	Architecture of the human erythrocyte ankyrin-1 complex.
7	AFDB:D3YZU1	0.051	0.060	2.780E-9	2167	0.146	0.179	D3YZU1.pdb.gz	SHAN1_MOUSE SH3 and multiple ankyrin repeat domains protein 1 OS=Mus musculus OX=10090 GN=Shank1 PE=1 SV=1
8	PDB:3ehqA	0.041	0.591	9.066E-9	182	0.014	0.209	3ehqA.pdb.gz
9	PDB:6jd6B	0.046	0.591	7.674E-8	192	0.015	0.203	6jd6B.pdb.gz
10	PDB:6v9hC	0.043	0.409	1.218E-7	270	0.016	0.156	6v9hC.pdb.gz
11	PDB:7df7B	0.041	0.882	1.933E-7	119	0.012	0.277	7df7B.pdb.gz
12	PDB:1bu9A	0.048	0.692	2.169E-7	168	0.015	0.244	1bu9A.pdb.gz
13	PDB:4oauC	0.045	0.171	2.435E-7	692	0.019	0.072	4oauC.pdb.gz	Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response.
14	PDB:6mwqA	0.046	0.243	2.895E-7	493	0.017	0.089	6mwqA.pdb.gz
15	PDB:1wg0A	0.048	0.500	3.249E-7	243	0.014	0.156	1wg0A.pdb.gz
16	AFDB:Q8N2N9	0.050	0.092	3.982E-7	1353	0.039	0.078	Q8N2N9.pdb.gz	AN36B_HUMAN Ankyrin repeat domain-containing protein 36B OS=Homo sapiens OX=9606 GN=ANKRD36B PE=1 SV=4
17	AFDB:A1Z9K8	0.051	0.071	3.003E-6	1871	0.076	0.108	A1Z9K8.pdb.gz	A1Z9K8_DROME LD13733p OS=Drosophila melanogaster OX=7227 GN=Prosap PE=2 SV=2
18	AFDB:Q9NZ56	0.028	0.037	9.529E-6	1722	0.086	0.132	Q9NZ56.pdb.gz	FMN2_HUMAN Formin-2 OS=Homo sapiens OX=9606 GN=FMN2 PE=1 SV=4
19	AFDB:Q0KHR2	0.053	0.069	2.018E-5	1918	0.076	0.106	Q0KHR2.pdb.gz	Q0KHR2_DROME Forked, isoform F OS=Drosophila melanogaster OX=7227 GN=f PE=4 SV=1
20	AFDB:Q9H2D6	0.034	0.037	5.705E-5	2365	0.127	0.143	Q9H2D6.pdb.gz	TARA_HUMAN TRIO and F-actin-binding protein OS=Homo sapiens OX=9606 GN=TRIOBP PE=1 SV=3

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	A0A2R8Y438	0.0	1517	944	0.329	0.928	A0A2R8Y438_HUMAN Ankyrin repeat domain containing 11 (Fragment) OS=Homo sapiens OX=9606 GN=ANKRD11 PE=1 SV=1
2	E9Q4F7	0.0	3670	2643	0.793	0.799	ANR11_MOUSE Ankyrin repeat domain-containing protein 11 OS=Mus musculus OX=10090 GN=Ankrd11 PE=1 SV=1
3	Q59GC3	0.0	798	439	0.146	0.886	Q59GC3_HUMAN Ankyrin repeat domain 11 variant (Fragment) OS=Homo sapiens OX=9606 PE=2 SV=1
4	Q6UB99	0.0	5388	2663	1.000	1.000	ANR11_HUMAN Ankyrin repeat domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ANKRD11 PE=1 SV=3
5	X5D778	3.77e-164	515	421	0.093	0.589	X5D778_HUMAN Ankyrin repeat domain 11 isoform A (Fragment) OS=Homo sapiens OX=9606 GN=ANKRD11 PE=1 SV=1
6	Q6UB98	3.62e-139	488	2062	0.087	0.113	ANR12_HUMAN Ankyrin repeat domain-containing protein 12 OS=Homo sapiens OX=9606 GN=ANKRD12 PE=1 SV=3
7	Q6PG48	3.66e-96	317	330	0.066	0.530	Q6PG48_HUMAN ANKRD12 protein OS=Homo sapiens OX=9606 GN=ANKRD12 PE=1 SV=1
8	Q8IQI3	8.29e-47	183	658	0.036	0.147	Q8IQI3_DROME Uncharacterized protein, isoform B OS=Drosophila melanogaster OX=7227 GN=Dmel\CG10984 PE=1 SV=2
9	Q99728	4.17e-30	132	777	0.030	0.104	BARD1_HUMAN BRCA1-associated RING domain protein 1 OS=Homo sapiens OX=9606 GN=BARD1 PE=1 SV=2
10	A0AVN2	4.51e-30	132	777	0.030	0.104	A0AVN2_HUMAN BRCA1 associated RING domain 1 OS=Homo sapiens OX=9606 GN=BARD1 PE=1 SV=1
11	Q90X95	3.54e-28	126	772	0.024	0.083	Q90X95_XENLA BRCA1 associated RING domain 1 L homeolog OS=Xenopus laevis OX=8355 GN=bard1.L PE=1 SV=1
12	Q9QZH2	4.30e-28	126	768	0.022	0.077	BARD1_RAT BRCA1-associated RING domain protein 1 OS=Rattus norvegicus OX=10116 GN=Bard1 PE=2 SV=1
13	O70445	1.99e-26	120	765	0.023	0.078	BARD1_MOUSE BRCA1-associated RING domain protein 1 OS=Mus musculus OX=10090 GN=Bard1 PE=2 SV=1
14	A0A140LI88	2.22e-25	118	1857	0.024	0.034	ANR31_MOUSE Ankyrin repeat domain-containing protein 31 OS=Mus musculus OX=10090 GN=Ankrd31 PE=1 SV=2
15	Q96HA7	3.42e-25	117	1378	0.020	0.039	TONSL_HUMAN Tonsoku-like protein OS=Homo sapiens OX=9606 GN=TONSL PE=1 SV=2
16	A0A087X2H0	3.86e-23	109	641	0.026	0.108	A0A087X2H0_HUMAN BRCA1 associated RING domain 1 OS=Homo sapiens OX=9606 GN=BARD1 PE=1 SV=2
17	Q9BQI6	4.51e-22	107	1058	0.024	0.060	SLF1_HUMAN SMC5-SMC6 complex localization factor protein 1 OS=Homo sapiens OX=9606 GN=SLF1 PE=1 SV=2
18	Q8R3P9	4.73e-22	107	1054	0.022	0.056	SLF1_MOUSE SMC5-SMC6 complex localization factor protein 1 OS=Mus musculus OX=10090 GN=Slf1 PE=1 SV=3
19	Q8CGN4	1.65e-20	102	1759	0.024	0.037	BCOR_MOUSE BCL-6 corepressor OS=Mus musculus OX=10090 GN=Bcor PE=1 SV=2
20	H7C2V9	5.36e-20	100	1690	0.023	0.037	H7C2V9_HUMAN BCL6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=2

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF00023 Ank	9e-14	62.4	Ankyrin repeat
2	PF12796 Ank_2	3.6e-15	67.6	Ankyrin repeats (3 copies)
3	PF13606 Ank_3	6.2e-10	49.3	Ankyrin repeat
4	PF13637 Ank_4	5.4e-13	60.4	Ankyrin repeats (many copies)
5	PF13857 Ank_5	2.7e-13	61.1	Ankyrin repeats (many copies)

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000301030

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000269305	0.750	Cellular tumor antigen p53
2	9606.ENSP00000301067	0.715	Histone-lysine N-methyltransferase 2D
3	9606.ENSP00000302967	0.698	Histone deacetylase 3
4	9606.ENSP00000405289	0.661	Zinc finger protein 778
5	9606.ENSP00000361066	0.651	Nuclear receptor coactivator 3
6	9606.ENSP00000399968	0.649	Nuclear receptor coactivator 2
7	9606.ENSP00000311513	0.642	Remodeling and spacing factor 1
8	9606.ENSP00000335320	0.626	B-cell CLL/lymphoma 9-like protein
9	9606.ENSP00000320543	0.624	Epsin-2
10	9606.ENSP00000385216	0.622	Nuclear receptor coactivator 1
11	9606.ENSP00000225983	0.620	Histone deacetylase 5
12	9606.ENSP00000263208	0.614	Protein HIRA
13	9606.ENSP00000264606	0.580	Histone deacetylase 4
14	9606.ENSP00000282516	0.578	Nipped-B-like protein
15	9606.ENSP00000350815	0.577	Mineralocorticoid receptor
16	9606.ENSP00000404570	0.558	Myosin-13
17	9606.ENSP00000372959	0.537	Leucine-rich repeat-containing protein 30
18	9606.ENSP00000344546	0.515	AT-rich interactive domain-containing protein 1B
19	9606.ENSP00000406209	0.502	Epsin-1

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0097159	0.450	organic cyclic compound binding
GO:1901363	0.428	heterocyclic compound binding
GO:0003676	0.402	nucleic acid binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0010171	0.975	body morphogenesis
GO:0060322	0.973	head development
GO:0032501	0.954	multicellular organismal process
GO:0060323	0.935	head morphogenesis
GO:0048513	0.924	animal organ development
GO:0001501	0.924	skeletal system development
GO:0009887	0.879	animal organ morphogenesis
GO:0009987	0.768	cellular process
GO:0065007	0.762	biological regulation
GO:0050789	0.719	regulation of biological process
GO:0050794	0.587	regulation of cellular process
GO:0042476	0.570	odontogenesis
GO:0019222	0.551	regulation of metabolic process
GO:0048705	0.438	skeletal system morphogenesis
GO:0060255	0.414	regulation of macromolecule metabolic process
GO:0031323	0.394	regulation of cellular metabolic process
GO:0080090	0.384	regulation of primary metabolic process
GO:0051171	0.377	regulation of nitrogen compound metabolic process
GO:0048518	0.374	positive regulation of biological process
GO:0008152	0.345	metabolic process
GO:0010468	0.345	regulation of gene expression
GO:0071704	0.340	organic substance metabolic process
GO:0044238	0.334	primary metabolic process
GO:0060324	0.300	face development

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005654	1.000	nucleoplasm
GO:0005829	0.999	cytosol
GO:0032991	0.484	protein-containing complex

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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