StarFunc result for job id Q7Z5N4

User Input

>input (2213 residues)
MARGARPSAAGGGGGGAEPPERAGPGRPRGSPPGRARPSLAPRPGPEPSRPRAAPETSGG
DTAGAGRCGGRRAAKLGPGRRGWWALLALQLHLLRALAQDDVAPYFKTEPGLPQIHLEGN
RLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSLQKLDAGFYRCVVRNRMGALLQ
RKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAI
TLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPG
NRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSFGRRLTISNPTSADTGPY
VCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQW
YKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAP
VFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQI
APVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHD
PRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMA
RLEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSN
VGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGR
TNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQ
YEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFING
INQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPS
TPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLT
HTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISN
ISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTP
YTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDS
QYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGA
GPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKD
LDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGP
PVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTAT
DLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWV
PGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIG
DSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRE
LEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAY
NIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIY
YWEADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQA
APGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNW
QRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTKSASELTL
QWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVA
VNEAGYGEPSNPSTAVSAQVEAPFYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKYKN
CSTGKGISTMEESVTLDNGGFAALELSSRHLNVKSTFSKKNGTRSPPRPSPGGLHYSDED
ICNKYNGAVLTESVSLKEKSADASESEATDSDYEDALPKHSFVNHYMSDPTYYNSWKRRA
QGRAPAPHRYEAVAGSEAGAQLHPVITTQSAGGVYTPAGPGARTPLTGFSSFV

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q7Z5N4	1.000	1.000	0.000	2213	1.000	1.000	Q7Z5N4.pdb.gz	SDK1_HUMAN Protein sidekick-1 OS=Homo sapiens OX=9606 GN=SDK1 PE=2 SV=3
2	AFDB:Q8AV58	0.330	0.335	0.000	2169	0.782	0.798	Q8AV58.pdb.gz	SDK1_CHICK Protein sidekick-1 OS=Gallus gallus OX=9031 GN=SDK1 PE=1 SV=1
3	AFDB:A0A0B4K6Z6	0.156	0.168	5.584E-67	2037	0.174	0.189	A0A0B4K6Z6.pdb.gz	A0A0B4K6Z6_DROME Down syndrome cell adhesion molecule 1, isoform BQ OS=Drosophila melanogaster OX=7227 GN=Dscam1 PE=1 SV=1
4	AFDB:P16621	0.085	0.092	6.734E-66	2029	0.142	0.155	P16621.pdb.gz	LAR_DROME Tyrosine-protein phosphatase Lar OS=Drosophila melanogaster OX=7227 GN=Lar PE=1 SV=2
5	AFDB:P32004	0.155	0.256	8.909E-57	1257	0.114	0.201	P32004.pdb.gz	L1CAM_HUMAN Neural cell adhesion molecule L1 OS=Homo sapiens OX=9606 GN=L1CAM PE=1 SV=2
6	AFDB:P43146	0.125	0.174	7.093E-55	1447	0.125	0.191	P43146.pdb.gz	DCC_HUMAN Netrin receptor DCC OS=Homo sapiens OX=9606 GN=DCC PE=1 SV=2
7	AFDB:Q9UQ52	0.155	0.314	1.988E-53	1028	0.113	0.243	Q9UQ52.pdb.gz	CNTN6_HUMAN Contactin-6 OS=Homo sapiens OX=9606 GN=CNTN6 PE=1 SV=1
8	AFDB:G3V7K1	0.082	0.105	1.644E-36	1464	0.106	0.161	G3V7K1.pdb.gz	G3V7K1_RAT Myomesin 2 OS=Rattus norvegicus OX=10116 GN=Myom2 PE=1 SV=2
9	AFDB:P54296	0.079	0.104	2.557E-36	1465	0.104	0.158	P54296.pdb.gz	MYOM2_HUMAN Myomesin-2 OS=Homo sapiens OX=9606 GN=MYOM2 PE=1 SV=3
10	AFDB:Q5VTT5	0.078	0.110	2.091E-33	1437	0.097	0.150	Q5VTT5.pdb.gz	MYOM3_HUMAN Myomesin-3 OS=Homo sapiens OX=9606 GN=MYOM3 PE=1 SV=1
11	PDB:5oj2B	0.072	0.200	3.076E-17	692	0.065	0.208	5oj2B.pdb.gz
12	PDB:1e07A	0.080	0.186	2.799E-13	642	0.047	0.160	1e07A.pdb.gz
13	PDB:5a42A	0.063	0.081	1.053E-12	1597	0.057	0.080	5a42A.pdb.gz
14	PDB:6pxvA	0.077	0.189	3.243E-12	823	0.026	0.070	6pxvA.pdb.gz
15	PDB:8dtlA	0.095	0.232	6.165E-12	741	0.030	0.089	8dtlA.pdb.gz
16	PDB:7q5zA	0.073	0.101	2.057E-11	1344	0.045	0.074	7q5zA.pdb.gz
17	PDB:8eyyA	0.075	0.193	1.304E-10	775	0.027	0.077	8eyyA.pdb.gz
18	PDB:7sqcO0	0.051	0.083	1.595E-10	1140	0.048	0.093	7sqcO0.pdb.gz	Ciliary central apparatus structure reveals mechanisms of microtubule patterning.
19	PDB:7q1yA	0.066	0.093	1.728E-10	1374	0.041	0.066	7q1yA.pdb.gz
20	PDB:6pyhD	0.077	0.193	5.537E-10	798	0.029	0.080	6pyhD.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	O97394	0.0	1255	2224	0.362	0.361	SDK_DROME Protein sidekick OS=Drosophila melanogaster OX=7227 GN=sdk PE=1 SV=2
2	Q3UH53	0.0	3980	2193	0.898	0.907	SDK1_MOUSE Protein sidekick-1 OS=Mus musculus OX=10090 GN=Sdk1 PE=1 SV=1
3	Q58EX2	0.0	2570	2172	0.577	0.588	SDK2_HUMAN Protein sidekick-2 OS=Homo sapiens OX=9606 GN=SDK2 PE=1 SV=3
4	Q6V4S5	0.0	2569	2176	0.573	0.583	SDK2_MOUSE Protein sidekick-2 OS=Mus musculus OX=10090 GN=Sdk2 PE=1 SV=1
5	Q7Z5N4	0.0	4532	2213	1.000	1.000	SDK1_HUMAN Protein sidekick-1 OS=Homo sapiens OX=9606 GN=SDK1 PE=2 SV=3
6	Q8AV57	0.0	2586	2177	0.584	0.593	SDK2_CHICK Protein sidekick-2 OS=Gallus gallus OX=9031 GN=SDK2 PE=1 SV=2
7	Q8AV58	0.0	3601	2169	0.785	0.801	SDK1_CHICK Protein sidekick-1 OS=Gallus gallus OX=9031 GN=SDK1 PE=1 SV=1
8	P20241	3.70e-93	335	1302	0.125	0.213	NRG_DROME Neuroglian OS=Drosophila melanogaster OX=7227 GN=Nrg PE=1 SV=2
9	F1NY98	3.80e-82	304	2034	0.156	0.170	DSCAM_CHICK Cell adhesion molecule DSCAM OS=Gallus gallus OX=9031 GN=DSCAM PE=1 SV=3
10	A0A8I5Y8T8	7.13e-81	295	1209	0.117	0.213	A0A8I5Y8T8_RAT Cell adhesion molecule L1-like OS=Rattus norvegicus OX=10116 GN=Chl1 PE=3 SV=1
11	A0A8I6A9A6	7.21e-80	292	1170	0.117	0.221	A0A8I6A9A6_RAT Cell adhesion molecule L1-like OS=Rattus norvegicus OX=10116 GN=Chl1 PE=3 SV=1
12	M0RC17	1.20e-79	292	1224	0.117	0.211	M0RC17_RAT Cell adhesion molecule L1-like OS=Rattus norvegicus OX=10116 GN=Chl1 PE=1 SV=3
13	O60469	1.18e-78	293	2012	0.154	0.169	DSCAM_HUMAN Cell adhesion molecule DSCAM OS=Homo sapiens OX=9606 GN=DSCAM PE=1 SV=2
14	Q8VHZ8	9.53e-78	290	2013	0.153	0.168	DSCAM_RAT Cell adhesion molecule DSCAM OS=Rattus norvegicus OX=10116 GN=Dscam PE=1 SV=1
15	Q9ERC8	9.95e-78	290	2013	0.153	0.168	DSCAM_MOUSE Cell adhesion molecule DSCAM OS=Mus musculus OX=10090 GN=Dscam PE=1 SV=1
16	Q62682	1.53e-77	283	1028	0.127	0.273	CNTN3_RAT Contactin-3 OS=Rattus norvegicus OX=10116 GN=Cntn3 PE=1 SV=1
17	Q0E9L9	4.31e-77	288	2018	0.142	0.156	Q0E9L9_DROME Down syndrome cell adhesion molecule 1, isoform AY OS=Drosophila melanogaster OX=7227 GN=Dscam1 PE=1 SV=1
18	Q9UQ52	6.88e-77	280	1028	0.128	0.275	CNTN6_HUMAN Contactin-6 OS=Homo sapiens OX=9606 GN=CNTN6 PE=1 SV=1
19	A0A0B4K7I5	7.60e-77	287	2016	0.143	0.157	A0A0B4K7I5_DROME Down syndrome cell adhesion molecule 1, isoform BT OS=Drosophila melanogaster OX=7227 GN=Dscam1 PE=1 SV=1
20	Q0E9H5	1.59e-76	286	2031	0.140	0.153	Q0E9H5_DROME Down syndrome cell adhesion molecule 1, isoform F OS=Drosophila melanogaster OX=7227 GN=Dscam1 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF07654 C1-set	0.089	24.5	Immunoglobulin C1-set domain
2	PF08205 C2-set_2	0.0055	28.0	CD80-like C2-set immunoglobulin domain
3	PF00041 fn3	5.7e-172	569.9	Fibronectin type III domain
4	PF07679 I-set	1.3e-65	228.8	Immunoglobulin I-set domain
5	PF00047 ig	1.9e-39	145.1	Immunoglobulin domain
6	PF13895 Ig_2	9.4e-40	146.1	Immunoglobulin domain
7	PF13927 Ig_3	1e-66	232.8	Immunoglobulin domain
8	PF16681 Ig_5	0.0011	30.7	Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
9	PF09294 Interfer-bind	3e-05	35.6	Interferon-alpha/beta receptor, fibronectin type III
10	PF10179 NDNF	1.9e+02	13.6	Neuron-derived neurotrophic factor, first Fn(III) domain
11	PF16656 Pur_ac_phosph_N	1.3e-23	94.7	Purple acid Phosphatase, N-terminal domain
12	PF07686 V-set	4.4e-11	54.3	Immunoglobulin V-set domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000385899

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000310491	0.565	Rho GTPase-activating protein 1
2	9606.ENSP00000306754	0.561	Neurogenic differentiation factor 2
3	9606.ENSP00000246841	0.555	Leucine-rich repeat transmembrane protein FLRT1
4	9606.ENSP00000306906	0.555	E3 ubiquitin-protein ligase RNF181
5	9606.ENSP00000173229	0.551	Netrin-1
6	9606.ENSP00000316244	0.550	5-hydroxytryptamine receptor 1A
7	9606.ENSP00000290039	0.524	VWFA and cache domain-containing protein 1
8	9606.ENSP00000383303	0.509	Down syndrome cell adhesion molecule
9	9606.ENSP00000393511	0.509	Actin-binding LIM protein 2
10	9606.ENSP00000347719	0.503	Tubulin-specific chaperone D

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0042802	0.991	identical protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.988	cellular process
GO:0050789	0.980	regulation of biological process
GO:0032501	0.940	multicellular organismal process
GO:0048856	0.928	anatomical structure development
GO:0007275	0.900	multicellular organism development
GO:0048731	0.888	system development
GO:0071840	0.849	cellular component organization or biogenesis
GO:0050896	0.842	response to stimulus
GO:0016043	0.786	cellular component organization
GO:0050794	0.716	regulation of cellular process
GO:0030154	0.416	cell differentiation
GO:0034330	0.394	cell junction organization
GO:0007399	0.382	nervous system development
GO:0009653	0.352	anatomical structure morphogenesis
GO:0007155	0.344	cell adhesion
GO:0042221	0.341	response to chemical

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005886	0.997	plasma membrane
GO:0030054	0.574	cell junction
GO:0005622	0.372	intracellular anatomical structure
GO:0043226	0.369	organelle

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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