StarFunc result for job id Q86Y25

User Input

>input (554 residues)
MAVDLLSAQEPVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSSLVSLGIPFSMPKL
IHQLQQGEDPCMVEREVPSDTRLGFKTWLETEALPHRQDIFIEETSQGMVKKESIKDGHW
DINFEEAVEFESEIEEEQEKKPLRQMIDSHEKTISEDGNHTSLELGKSLFTNTALVTQQS
VPIERIPNMYYTFGKDFKQNFDLMKCFQIYPGGKPHICNECGKSFKQNLHLIEHQRIHTG
EKPYKCNECEKTFSHRSSLLSHQRIHTGEKPYKCNECEKAFSNSSTLIKHLRVHTGEKPY
RCRECGKAFSQCSTLTVHQRIHTGEKLYKCGECEKAFNCRAKLHRHQRIHTGEKPYKCSE
CGKGYSQFTSLAEHQRFHTGEQLYTCLECGRTFTRIVTLIEHQRIHTGQKPYQCNECEKA
FNQYSSFNEHRKIHTGEKLYTCEECGKAFGCKSNLYRHQRIHTGEKPYQCNQCGKAFSQY
SFLTEHERIHTGEKLYKCMECGKAYSYRSNLCRHKKVHTKEKLYKWKEYGKPFICSSSLT
QYQRFFKGDKAYEV

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q86Y25	1.000	1.000	5.104E-89	554	1.000	1.000	Q86Y25.pdb.gz	Z354C_HUMAN Zinc finger protein 354C OS=Homo sapiens OX=9606 GN=ZNF354C PE=1 SV=1
2	AFDB:Q571J5	0.563	0.558	1.380E-64	560	0.756	0.748	Q571J5.pdb.gz	Z354C_MOUSE Zinc finger protein 354C OS=Mus musculus OX=10090 GN=Znf354c PE=2 SV=2
3	AFDB:Q6ECI4	0.527	0.416	5.399E-49	717	0.453	0.350	Q6ECI4.pdb.gz	ZN470_HUMAN Zinc finger protein 470 OS=Homo sapiens OX=9606 GN=ZNF470 PE=2 SV=3
4	AFDB:Q9P2J8	0.485	0.326	1.089E-48	865	0.462	0.296	Q9P2J8.pdb.gz	ZN624_HUMAN Zinc finger protein 624 OS=Homo sapiens OX=9606 GN=ZNF624 PE=1 SV=3
5	AFDB:Q9BX82	0.340	0.304	7.607E-48	626	0.457	0.404	Q9BX82.pdb.gz	ZN471_HUMAN Zinc finger protein 471 OS=Homo sapiens OX=9606 GN=ZNF471 PE=2 SV=1
6	AFDB:Q8TF47	0.296	0.267	3.268E-47	636	0.460	0.401	Q8TF47.pdb.gz	ZFP90_HUMAN Zinc finger protein 90 homolog OS=Homo sapiens OX=9606 GN=ZFP90 PE=1 SV=2
7	AFDB:P52742	0.524	0.451	3.843E-47	658	0.446	0.375	P52742.pdb.gz	ZN135_HUMAN Zinc finger protein 135 OS=Homo sapiens OX=9606 GN=ZNF135 PE=1 SV=3
8	AFDB:Q14587	0.436	0.283	5.313E-47	947	0.451	0.264	Q14587.pdb.gz	ZN268_HUMAN Zinc finger protein 268 OS=Homo sapiens OX=9606 GN=ZNF268 PE=1 SV=2
9	AFDB:P15622	0.498	0.493	7.752E-47	560	0.448	0.443	P15622.pdb.gz	ZN250_HUMAN Zinc finger protein 250 OS=Homo sapiens OX=9606 GN=ZNF250 PE=1 SV=3
10	AFDB:Q06732	0.470	0.352	2.282E-46	778	0.457	0.325	Q06732.pdb.gz	ZN33B_HUMAN Zinc finger protein 33B OS=Homo sapiens OX=9606 GN=ZNF33B PE=1 SV=2
11	PDB:3w5kB	0.088	0.268	4.446E-4	110	0.069	0.345	3w5kB.pdb.gz	Structural basis for the selective nuclear import of the C2H2 zinc-finger protein Snail by importin beta.
12	PDB:5dkaA	0.057	0.245	8.075E-1	96	0.029	0.167	5dkaA.pdb.gz	A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125.
13	PDB:8ap8d	0.073	0.126	1.058	270	0.060	0.122	8ap8d.pdb.gz
14	PDB:6ydhA	0.031	0.211	1.178	62	0.027	0.242	6ydhA.pdb.gz
15	PDB:6ff79	0.065	0.079	1.313	432	0.072	0.093	6ff79.pdb.gz	Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
16	PDB:7qo48	0.063	0.081	2.022	372	0.034	0.051	7qo48.pdb.gz	Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
17	PDB:7ena4	0.068	0.076	2.134	457	0.065	0.079	7ena4.pdb.gz	Structures of the human Mediator and Mediator-bound preinitiation complex.
18	PDB:4yrvA	0.074	0.095	2.252	288	0.056	0.108	4yrvA.pdb.gz	Structural insights into HetR-PatS interaction involved in cyanobacterial pattern formation
19	PDB:5c8dE	0.067	0.103	2.252	280	0.051	0.100	5c8dE.pdb.gz	Structural basis for gene regulation by a B12-dependent photoreceptor.
20	PDB:7cunA	0.070	0.058	2.377	730	0.072	0.055	7cunA.pdb.gz	Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q571J5	0.0	870	560	0.762	0.754	Z354C_MOUSE Zinc finger protein 354C OS=Mus musculus OX=10090 GN=Znf354c PE=2 SV=2
2	Q86Y25	0.0	1151	554	1.000	1.000	Z354C_HUMAN Zinc finger protein 354C OS=Homo sapiens OX=9606 GN=ZNF354C PE=1 SV=1
3	O60765	3.21e-164	482	605	0.458	0.420	Z354A_HUMAN Zinc finger protein 354A OS=Homo sapiens OX=9606 GN=ZNF354A PE=1 SV=2
4	V9HWI2	3.21e-164	482	605	0.458	0.420	V9HWI2_HUMAN Epididymis luminal protein 104 OS=Homo sapiens OX=9606 GN=HEL104 PE=2 SV=1
5	Q03923	2.77e-160	471	595	0.495	0.461	ZNF85_HUMAN Zinc finger protein 85 OS=Homo sapiens OX=9606 GN=ZNF85 PE=1 SV=3
6	Q6ECI4	3.96e-158	470	717	0.473	0.365	ZN470_HUMAN Zinc finger protein 470 OS=Homo sapiens OX=9606 GN=ZNF470 PE=2 SV=3
7	A0A0A0MS50	8.25e-158	465	604	0.480	0.440	A0A0A0MS50_HUMAN Zinc finger protein 300 OS=Homo sapiens OX=9606 GN=ZNF300 PE=1 SV=1
8	P52742	1.23e-157	467	658	0.455	0.383	ZN135_HUMAN Zinc finger protein 135 OS=Homo sapiens OX=9606 GN=ZNF135 PE=1 SV=3
9	Q8TAQ5	3.75e-157	466	688	0.475	0.382	ZN420_HUMAN Zinc finger protein 420 OS=Homo sapiens OX=9606 GN=ZNF420 PE=1 SV=1
10	Q96RE9	8.30e-157	463	604	0.473	0.434	ZN300_HUMAN Zinc finger protein 300 OS=Homo sapiens OX=9606 GN=ZNF300 PE=1 SV=1
11	P35789	1.04e-156	463	620	0.460	0.411	ZNF93_HUMAN Zinc finger protein 93 OS=Homo sapiens OX=9606 GN=ZNF93 PE=1 SV=4
12	Q08ER8	3.71e-156	461	600	0.473	0.437	ZN543_HUMAN Zinc finger protein 543 OS=Homo sapiens OX=9606 GN=ZNF543 PE=1 SV=3
13	P15622	5.66e-156	459	560	0.451	0.446	ZN250_HUMAN Zinc finger protein 250 OS=Homo sapiens OX=9606 GN=ZNF250 PE=1 SV=3
14	Q9BX82	5.31e-155	459	626	0.480	0.425	ZN471_HUMAN Zinc finger protein 471 OS=Homo sapiens OX=9606 GN=ZNF471 PE=2 SV=1
15	Q8IYB9	1.33e-154	459	648	0.477	0.407	ZN595_HUMAN Zinc finger protein 595 OS=Homo sapiens OX=9606 GN=ZNF595 PE=1 SV=2
16	Q8TF47	1.43e-154	458	636	0.477	0.415	ZFP90_HUMAN Zinc finger protein 90 homolog OS=Homo sapiens OX=9606 GN=ZFP90 PE=1 SV=2
17	A0A0C4DG42	8.02e-152	447	539	0.433	0.445	A0A0C4DG42_HUMAN Zinc finger protein 34 OS=Homo sapiens OX=9606 GN=ZNF34 PE=1 SV=1
18	Q8IZ26	2.26e-151	447	560	0.433	0.429	ZNF34_HUMAN Zinc finger protein 34 OS=Homo sapiens OX=9606 GN=ZNF34 PE=1 SV=3
19	Q9P2J8	3.03e-151	457	865	0.462	0.296	ZN624_HUMAN Zinc finger protein 624 OS=Homo sapiens OX=9606 GN=ZNF624 PE=1 SV=3
20	Q8NA42	1.77e-150	442	475	0.435	0.507	ZN383_HUMAN Zinc finger protein 383 OS=Homo sapiens OX=9606 GN=ZNF383 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF01352 KRAB	4.5e-20	82.3	KRAB box
2	PF01286 XPA_N	84	14.6	XPA protein N-terminal
3	PF00096 zf-C2H2	4.5e-49	173.4	Zinc finger, C2H2 type
4	PF16622 zf-C2H2_11	0.014	26.4	zinc-finger C2H2-type
5	PF13894 zf-C2H2_4	4.2e-27	103.5	C2H2-type zinc finger
6	PF13912 zf-C2H2_6	4.7e-10	50.5	C2H2-type zinc finger
7	PF12171 zf-C2H2_jaz	1.2e+02	14.3	Zinc-finger double-stranded RNA-binding
8	PF13465 zf-H2C2_2	5.6e-83	281.2	Zinc-finger double domain
9	PF13909 zf-H2C2_5	13	17.0	C2H2-type zinc-finger domain
10	PF18439 zf_UBZ	0.17	22.8	Ubiquitin-Binding Zinc Finger
11	PF17032 zinc_ribbon_15	0.66	22.1	zinc-ribbon family
12	PF09723 Zn-ribbon_8	0.012	27.1	Zinc ribbon domain
13	PF12760 Zn_Tnp_IS1595	37	15.6	Transposase zinc-ribbon domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000324064

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000326272	0.691	Forkhead box protein L1
2	9606.ENSP00000315731	0.653	Meteorin-like protein
3	9606.ENSP00000452871	0.604	Transducin-like enhancer protein 3

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0003676	0.618	nucleic acid binding
GO:0003677	0.530	DNA binding
GO:0043565	0.460	sequence-specific DNA binding
GO:1990837	0.450	sequence-specific double-stranded DNA binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0006355	0.997	regulation of DNA-templated transcription
GO:0048518	0.782	positive regulation of biological process
GO:0048522	0.758	positive regulation of cellular process
GO:0006357	0.682	regulation of transcription by RNA polymerase II
GO:0009893	0.597	positive regulation of metabolic process
GO:0048523	0.594	negative regulation of cellular process
GO:0010604	0.587	positive regulation of macromolecule metabolic process
GO:0051173	0.575	positive regulation of nitrogen compound metabolic process
GO:0031325	0.575	positive regulation of cellular metabolic process
GO:0009891	0.566	positive regulation of biosynthetic process
GO:0031328	0.563	positive regulation of cellular biosynthetic process
GO:0045935	0.563	positive regulation of nucleobase-containing compound metabolic process
GO:1903508	0.547	positive regulation of nucleic acid-templated transcription
GO:0045893	0.544	positive regulation of DNA-templated transcription
GO:0031324	0.486	negative regulation of cellular metabolic process
GO:0051172	0.483	negative regulation of nitrogen compound metabolic process
GO:0010605	0.461	negative regulation of macromolecule metabolic process
GO:0031327	0.396	negative regulation of cellular biosynthetic process
GO:0010558	0.387	negative regulation of macromolecule biosynthetic process
GO:0051253	0.386	negative regulation of RNA metabolic process
GO:0009987	0.385	cellular process
GO:1902679	0.384	negative regulation of RNA biosynthetic process
GO:0032502	0.380	developmental process
GO:0045892	0.321	negative regulation of DNA-templated transcription

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005654	0.998	nucleoplasm

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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