StarFunc result for job id Q8N5D0

User Input

>input (677 residues)
MAKVNITRDLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQGHSGCVNCLEWNEKGD
LLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHAGDRILITGAADSKVHVHD
LTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIRQYDLRENSKHSEVLIDLTEY
CGQLVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIHNHRKSMKQSPSAGVHTFCDRQK
PLPDGAAQYYVAGHLPVKLPDYNNRLRVLVATYVTFSPNGTELLVNMGGEQVYLFDLTYK
QRPYTFLLPRKCHSSGEVQNGKMSTNGVSNGVSNGLHLHSNGFRLPESRGHVSPQVELPP
YLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHYDALR
DCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDALGRDIT
AALFSKNDGEEKKGPGGGAPVRLRSTSRKDSISEDEMVLRERSYDYQFRYCGHCNTTTDI
KEANFFGSNAQYIVSGSDDGSFFIWEKETTNLVRVLQGDESIVNCLQPHPSYCFLATSGI
DPVVRLWNPRPESEDLTGRVVEDMEGASQANQRRMNADPLEVMLLNMGYRITGLSSGGAG
ASDDEDSSEGQVQCRPS

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q80ZK9	0.931	0.931	0.000	677	0.970	0.970	Q80ZK9.pdb.gz	WDTC1_MOUSE WD and tetratricopeptide repeats protein 1 OS=Mus musculus OX=10090 GN=Wdtc1 PE=1 SV=1
2	AFDB:Q7K7W5	0.780	0.840	1.105E-57	628	0.350	0.377	Q7K7W5.pdb.gz	Q7K7W5_DROME Adipose protein OS=Drosophila melanogaster OX=7227 GN=adp PE=2 SV=1
3	AFDB:Q94BQ3	0.694	0.625	4.464E-44	757	0.318	0.284	Q94BQ3.pdb.gz	ASG2_ARATH Protein ALTERED SEED GERMINATION 2 OS=Arabidopsis thaliana OX=3702 GN=ASG2 PE=1 SV=1
4	AFDB:O94527	0.513	0.433	3.495E-34	809	0.230	0.193	O94527.pdb.gz	IQW1_SCHPO WD repeat protein iqw1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=iqw1 PE=1 SV=1
5	AFDB:Q5TAQ9	0.522	0.589	2.526E-28	597	0.219	0.248	Q5TAQ9.pdb.gz	DCAF8_HUMAN DDB1- and CUL4-associated factor 8 OS=Homo sapiens OX=9606 GN=DCAF8 PE=1 SV=1
6	AFDB:F4JTP6	0.477	0.674	6.460E-28	471	0.205	0.295	F4JTP6.pdb.gz	F4JTP6_ARATH Transducin/WD40 repeat-like superfamily protein OS=Arabidopsis thaliana OX=3702 GN=ABD1 PE=1 SV=1
7	AFDB:F4J6P6	0.494	0.641	3.299E-27	515	0.211	0.278	F4J6P6.pdb.gz	F4J6P6_ARATH Transducin/WD40 repeat-like superfamily protein OS=Arabidopsis thaliana OX=3702 GN=At3g45620 PE=1 SV=1
8	AFDB:Q58WW2	0.497	0.396	1.217E-25	860	0.251	0.198	Q58WW2.pdb.gz	DCAF6_HUMAN DDB1- and CUL4-associated factor 6 OS=Homo sapiens OX=9606 GN=DCAF6 PE=1 SV=1
9	AFDB:Q57YE7	0.434	0.274	7.430E-21	1086	0.191	0.119	Q57YE7.pdb.gz	Q57YE7_TRYB2 Guanine nucleotide-binding protein subunit beta-like protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb08.12O16.420 PE=4 SV=1
10	PDB:2h9lA	0.396	0.808	2.361E-15	321	0.109	0.231	2h9lA.pdb.gz
11	AFDB:Q54XN8	0.426	0.877	5.111E-15	319	0.115	0.245	Q54XN8.pdb.gz	Q54XN8_DICDI Anaphase-promoting complex subunit 4-like WD40 domain-containing protein OS=Dictyostelium discoideum OX=44689 GN=DDB_G0278945 PE=3 SV=1
12	PDB:5mzhB	0.398	0.620	2.634E-12	415	0.095	0.154	5mzhB.pdb.gz
13	PDB:7mqaLO	0.237	0.199	2.767E-12	819	0.123	0.101	7mqaLO.pdb.gz	Nucleolar maturation of the human small subunit processome.
14	PDB:4v6wAg	0.280	0.576	1.104E-11	318	0.077	0.164	4v6wAg.pdb.gz	Structures of the human and Drosophila 80S ribosome.
15	PDB:5yzgs	0.299	0.528	1.219E-11	374	0.071	0.128	5yzgs.pdb.gz	Structure of a human catalytic step I spliceosome
16	PDB:7mq8LJ	0.259	0.369	1.219E-11	469	0.105	0.151	7mq8LJ.pdb.gz	Nucleolar maturation of the human small subunit processome.
17	PDB:7jvrB	0.252	0.457	1.345E-11	342	0.081	0.161	7jvrB.pdb.gz	Structural insights into the human D1 and D2 dopamine receptor signaling complexes.
18	PDB:3zwlD	0.260	0.486	1.560E-11	352	0.069	0.134	3zwlD.pdb.gz
19	PDB:6bk8D	0.382	0.693	1.639E-11	359	0.081	0.153	6bk8D.pdb.gz	Structure of the yeast spliceosomal postcatalytic P complex.
20	PDB:7vggA	0.392	0.843	1.722E-11	304	0.089	0.197	7vggA.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q80ZK9	0.0	1380	677	0.970	0.970	WDTC1_MOUSE WD and tetratricopeptide repeats protein 1 OS=Mus musculus OX=10090 GN=Wdtc1 PE=1 SV=1
2	Q8N5D0	0.0	1424	677	1.000	1.000	WDTC1_HUMAN WD and tetratricopeptide repeats protein 1 OS=Homo sapiens OX=9606 GN=WDTC1 PE=1 SV=2
3	Q7K7W5	6.98e-128	394	628	0.355	0.382	Q7K7W5_DROME Adipose protein OS=Drosophila melanogaster OX=7227 GN=adp PE=2 SV=1
4	Q95TD6	6.28e-67	223	298	0.176	0.399	Q95TD6_DROME SD07783p OS=Drosophila melanogaster OX=7227 GN=adp PE=2 SV=1
5	Q94BQ3	8.05e-56	205	757	0.238	0.213	ASG2_ARATH Protein ALTERED SEED GERMINATION 2 OS=Arabidopsis thaliana OX=3702 GN=ASG2 PE=1 SV=1
6	Q9M1E5	2.26e-37	147	481	0.145	0.204	Q9M1E5_ARATH Transducin/WD40 repeat-like superfamily protein OS=Arabidopsis thaliana OX=3702 GN=F9K21.200 PE=1 SV=1
7	F4J6P6	3.61e-35	142	515	0.139	0.183	F4J6P6_ARATH Transducin/WD40 repeat-like superfamily protein OS=Arabidopsis thaliana OX=3702 GN=At3g45620 PE=1 SV=1
8	Q5TAQ9	3.32e-33	137	597	0.124	0.141	DCAF8_HUMAN DDB1- and CUL4-associated factor 8 OS=Homo sapiens OX=9606 GN=DCAF8 PE=1 SV=1
9	F4JTP6	1.26e-31	130	471	0.130	0.187	F4JTP6_ARATH Transducin/WD40 repeat-like superfamily protein OS=Arabidopsis thaliana OX=3702 GN=ABD1 PE=1 SV=1
10	Q58WW2	2.76e-28	123	860	0.130	0.102	DCAF6_HUMAN DDB1- and CUL4-associated factor 6 OS=Homo sapiens OX=9606 GN=DCAF6 PE=1 SV=1
11	O94527	2.57e-25	114	809	0.143	0.120	IQW1_SCHPO WD repeat protein iqw1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=iqw1 PE=1 SV=1
12	Q57YE7	1.15e-21	102	1086	0.115	0.072	Q57YE7_TRYB2 Guanine nucleotide-binding protein subunit beta-like protein OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb08.12O16.420 PE=4 SV=1
13	Q8TBB7	4.07e-16	82.4	326	0.086	0.178	Q8TBB7_HUMAN DDB1 and CUL4 associated factor 5 OS=Homo sapiens OX=9606 GN=DCAF5 PE=1 SV=1
14	Q80T85	1.11e-15	83.6	946	0.086	0.061	DCAF5_MOUSE DDB1- and CUL4-associated factor 5 OS=Mus musculus OX=10090 GN=Dcaf5 PE=1 SV=2
15	Q96JK2	1.12e-15	83.6	942	0.086	0.062	DCAF5_HUMAN DDB1- and CUL4-associated factor 5 OS=Homo sapiens OX=9606 GN=DCAF5 PE=1 SV=2
16	Q10282	3.14e-11	67.4	305	0.061	0.134	GBB_SCHPO Guanine nucleotide-binding protein subunit beta OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=git5 PE=3 SV=2
17	O70593	3.78e-11	67.0	314	0.052	0.111	SGTA_RAT Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Rattus norvegicus OX=10116 GN=Sgta PE=1 SV=1
18	Q9UTN4	6.54e-11	67.8	509	0.064	0.084	PFS2_SCHPO Polyadenylation factor subunit 2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=pfs2 PE=4 SV=1
19	O43765	2.60e-10	64.7	313	0.056	0.121	SGTA_HUMAN Small glutamine-rich tetratricopeptide repeat-containing protein alpha OS=Homo sapiens OX=9606 GN=SGTA PE=1 SV=1
20	Q9MUK5	2.68e-10	65.9	593	0.055	0.062	TOC64_PEA Translocon at the outer membrane of chloroplasts 64 OS=Pisum sativum OX=3888 GN=TOC64 PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF12895 ANAPC3	0.4	22.3	Anaphase-promoting complex, cyclosome, subunit 3
2	PF12894 ANAPC4_WD40	0.048	25.3	Anaphase-promoting complex subunit 4 WD40 domain
3	PF20426 NBCH_WD40	2.8	18.3	Neurobeachin beta propeller domain
4	PF00515 TPR_1	0.0028	28.6	Tetratricopeptide repeat
5	PF13414 TPR_11	0.13	23.3	TPR repeat
6	PF13428 TPR_14	0.27	23.2	Tetratricopeptide repeat
7	PF13432 TPR_16	76	15.3	Tetratricopeptide repeat
8	PF13431 TPR_17	2.2	19.9	Tetratricopeptide repeat
9	PF14559 TPR_19	5.5e-05	34.9	Tetratricopeptide repeat
10	PF07719 TPR_2	0.0032	28.5	Tetratricopeptide repeat
11	PF13174 TPR_6	0.51	22.2	Tetratricopeptide repeat
12	PF13181 TPR_8	1.1e+02	14.4	Tetratricopeptide repeat
13	PF13371 TPR_9	81	14.7	Tetratricopeptide repeat
14	PF00400 WD40	5.7e-19	79.3	WD domain, G-beta repeat

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 60711.ENSCSAP00000017020

Rank	PPI partner	STRING score	Description
1	60711.ENSCSAP00000002685	0.987	Damage-specific DNA binding protein 1, 127kDa
2	60711.ENSCSAP00000013471	0.917	Cullin 4A
3	60711.ENSCSAP00000014347	0.917	Cullin 4B
4	60711.ENSCSAP00000000772	0.895	COP9 signalosome subunit 4
5	60711.ENSCSAP00000010231	0.893	COP9 signalosome subunit 5
6	60711.ENSCSAP00000018448	0.890	COP9 signalosome subunit 8
7	60711.ENSCSAP00000013856	0.879	COP9 signalosome subunit 6
8	60711.ENSCSAP00000001933	0.864	DET1 and DDB1 associated 1
9	60711.ENSCSAP00000009010	0.782	DDB1 and CUL4 associated factor 4
10	60711.ENSCSAP00000019185	0.782	DDB1 and CUL4 associated factor 4-like 1
11	60711.ENSCSAP00000007711	0.777	COMM domain containing 2
12	60711.ENSCSAP00000007257	0.756	DDB1 and CUL4 associated factor 6
13	60711.ENSCSAP00000007057	0.750	DDB1 and CUL4 associated factor 10
14	60711.ENSCSAP00000002004	0.741	Damage-specific DNA binding protein 2, 48kDa
15	60711.ENSCSAP00000006870	0.740	COP9 signalosome subunit 2
16	60711.ENSCSAP00000005764	0.725	Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
17	60711.ENSCSAP00000009272	0.725	DDB1 and CUL4 associated factor 5
18	60711.ENSCSAP00000004724	0.722	COP9 signalosome subunit 3
19	60711.ENSCSAP00000012262	0.715	DDB1 and CUL4 associated factor 11
20	60711.ENSCSAP00000011668	0.713	WD repeat domain 5

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0050794	0.997	regulation of cellular process
GO:0071704	0.993	organic substance metabolic process
GO:0044238	0.993	primary metabolic process
GO:0009987	0.988	cellular process
GO:0019222	0.986	regulation of metabolic process
GO:0080090	0.937	regulation of primary metabolic process
GO:0031323	0.932	regulation of cellular metabolic process
GO:0050896	0.903	response to stimulus
GO:0060255	0.888	regulation of macromolecule metabolic process
GO:0048519	0.887	negative regulation of biological process
GO:0051171	0.885	regulation of nitrogen compound metabolic process
GO:0048523	0.871	negative regulation of cellular process
GO:0019219	0.781	regulation of nucleobase-containing compound metabolic process
GO:0031326	0.692	regulation of cellular biosynthetic process
GO:0009892	0.661	negative regulation of metabolic process
GO:0006807	0.636	nitrogen compound metabolic process
GO:0051716	0.610	cellular response to stimulus
GO:0043170	0.604	macromolecule metabolic process
GO:0010605	0.583	negative regulation of macromolecule metabolic process
GO:0071840	0.567	cellular component organization or biogenesis
GO:0051172	0.565	negative regulation of nitrogen compound metabolic process
GO:0010468	0.538	regulation of gene expression
GO:0045934	0.529	negative regulation of nucleobase-containing compound metabolic process
GO:0010556	0.511	regulation of macromolecule biosynthetic process
GO:0016043	0.500	cellular component organization
GO:0048518	0.484	positive regulation of biological process
GO:0044237	0.484	cellular metabolic process
GO:0051252	0.477	regulation of RNA metabolic process
GO:0042221	0.443	response to chemical
GO:0019216	0.421	regulation of lipid metabolic process
GO:0032502	0.408	developmental process
GO:0010033	0.402	response to organic substance
GO:0032501	0.379	multicellular organismal process
GO:0031327	0.366	negative regulation of cellular biosynthetic process
GO:0048856	0.364	anatomical structure development
GO:1901564	0.351	organonitrogen compound metabolic process
GO:0048522	0.326	positive regulation of cellular process
GO:2001141	0.308	regulation of RNA biosynthetic process
GO:0009893	0.302	positive regulation of metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005654	0.998	nucleoplasm
GO:0005829	0.995	cytosol
GO:0032991	0.936	protein-containing complex
GO:1990234	0.727	transferase complex
GO:0140535	0.650	intracellular protein-containing complex
GO:0000151	0.595	ubiquitin ligase complex
GO:0031461	0.593	cullin-RING ubiquitin ligase complex
GO:0080008	0.301	Cul4-RING E3 ubiquitin ligase complex

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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