StarFunc result for job id Q9BXR3

User Input

>input (956 residues)
NKSRKRRNRESLLGAATVEPPKPIPLTWKTEKPVWVNQWPLPKQKLEALHLLANEQLEKG
HIEPSFSPWNSPVFVIQKKSGKWRMLTDLRAVNAVIQPMGPLQPGLPSPAMIPKDWPLII
IDLKDCFFTIPLAEQDCEKFAFTIPAINNKEPATRFQWKVLPQGMLNSPTICQTFVGRAL
QPVREKFSDCYIIHCIDDILCAAETKDKLIDCYTFLQAEVANAGLAIASDKIQTSTPFHY
LGMQIENRKIKPQKIEIRKDTLKTLNDFQKLLGDINWIRPTLGIPTYAMSNLFSILRGDS
DLNSKRMLTPEATKEIKLVEEKIQSAQINRIDPLAPLQLLIFATAHSPTGIIIQNTDLVE
WSFLPHSTVKTFTLYLDQIATLIGQTRLRIIKLCGNDPDKIVVPLTKEQVRQAFINSGAW
KIGLANFVGIIDNHYPKTKIFQFLKLTTWILPKITRREPLENALTVFTDGSSNGKAAYTG
PKERVIKTPYQSAQRAELVAVITVLQDFDQPINIISDSAYVVQATRDVETALIKYSMDDQ
LNQLFNLLQQTVRKRNFPFYITHIRAHTNLPGPLTKANEQADLLVSSALIKAQELHALTH
VNAAGLKNKFDVTWKQAKDIVQHCTQCQVLHLPTQEAGVNPRGLCPNALWQMDVTHVPSF
GRLSYVHVTVDTYSHFIWATCQTGESTSHVKKHLLSCFAVMGVPEKIKTDNGPGYCSKAF
QKFLSQWKISHTTGIPYNSQGQAIVERTNRTLKTQLVKQKEGGDSKECTTPQMQLNLALY
TLNFLNIYRNQTTTSAEQHLTGKKNSPHEGKLIWWKDNKNKTWEIGKVITWGRGFACVSP
GENQLPVWIPTRHLKFYNEPIRDAKKSTSAETETSQSSTVDSQDEQNGDVRRTDEVAIHQ
EGRAANLGTTKEADAVSYKISREHKGDTNPREYAACSLDDCINGGKSPYACRSSCS

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	PDB:2jleA	0.487	0.819	4.418E-36	545	0.158	0.277	2jleA.pdb.gz	Novel Indazole Non-Nucleoside Reverse Transcriptase Inhibitors Using Molecular Hybridization Based on Crystallographic Overlays.
2	AFDB:P0CT40	0.387	0.285	4.762E-36	1333	0.174	0.125	P0CT40.pdb.gz	TF29_SCHPO Transposon Tf2-9 polyprotein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=Tf2-9 PE=3 SV=1
3	AFDB:Q99315	0.228	0.149	4.868E-32	1547	0.150	0.092	Q99315.pdb.gz	YG31B_YEAST Transposon Ty3-G Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TY3B-G PE=1 SV=3
4	AFDB:Q7LHG5	0.231	0.155	1.513E-31	1498	0.151	0.096	Q7LHG5.pdb.gz	YI31B_YEAST Transposon Ty3-I Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TY3B-I PE=1 SV=2
5	AFDB:P71639	0.194	0.362	1.339E-9	469	0.051	0.104	P71639.pdb.gz	P71639_MYCTU Probable transposase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2812 PE=4 SV=2
6	AFDB:Q6ZNG9	0.182	0.331	1.100E-8	492	0.042	0.081	Q6ZNG9.pdb.gz	KRBA2_HUMAN KRAB-A domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KRBA2 PE=1 SV=1
7	PDB:7q5bB	0.147	0.274	6.059E-8	482	0.054	0.108	7q5bB.pdb.gz	Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
8	AFDB:Q6R2W3	0.138	0.102	3.018E-6	1325	0.036	0.026	Q6R2W3.pdb.gz	SCND3_HUMAN SCAN domain-containing protein 3 OS=Homo sapiens OX=9606 GN=SCAND3 PE=1 SV=1
9	PDB:6vrdA	0.106	0.586	5.758E-5	149	0.032	0.208	6vrdA.pdb.gz	Crystal structure of RNase H/RNA/PS-ASO complex at an atomic level
10	PDB:7lmaA	0.126	0.119	8.113E-4	1012	0.043	0.041	7lmaA.pdb.gz	Structures of telomerase at several steps of telomere repeat synthesis.
11	PDB:7x3kB	0.077	0.131	1.122E-3	506	0.051	0.097	7x3kB.pdb.gz
12	PDB:7qxaA	0.173	0.174	2.031E-3	954	0.074	0.074	7qxaA.pdb.gz	Structural basis of human telomerase recruitment by TPP1-POT1.
13	PDB:1rddA	0.096	0.443	4.098E-3	155	0.029	0.181	1rddA.pdb.gz	Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site.
14	PDB:5z56A	0.080	0.037	4.326E-3	2232	0.046	0.020	5z56A.pdb.gz	Structure of the human activated spliceosome in three conformational states.
15	PDB:6x5hA	0.078	0.127	6.312E-3	467	0.044	0.090	6x5hA.pdb.gz	Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases.
16	PDB:7kpvD	0.082	0.088	7.422E-3	876	0.030	0.033	7kpvD.pdb.gz
17	AFDB:Q8N5A5	0.053	0.093	8.001E-3	531	0.053	0.096	Q8N5A5.pdb.gz	ZGPAT_HUMAN Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3
18	AFDB:Q8IWW6	0.054	0.060	8.154E-2	846	0.030	0.034	Q8IWW6.pdb.gz	RHG12_HUMAN Rho GTPase-activating protein 12 OS=Homo sapiens OX=9606 GN=ARHGAP12 PE=1 SV=1
19	AFDB:Q6TLK4	0.052	0.057	1.012E-1	869	0.026	0.029	Q6TLK4.pdb.gz	RHG27_RAT Rho GTPase-activating protein 27 OS=Rattus norvegicus OX=10116 GN=Arhgap27 PE=1 SV=1
20	AFDB:Q9BRR9	0.054	0.067	1.068E-1	750	0.016	0.020	Q9BRR9.pdb.gz	RHG09_HUMAN Rho GTPase-activating protein 9 OS=Homo sapiens OX=9606 GN=ARHGAP9 PE=1 SV=2

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	P03354	1.27e-151	490	1603	0.339	0.202	POL_RSVP Gag-Pol polyprotein OS=Rous sarcoma virus subgroup C (strain Prague) OX=11888 GN=gag-pol PE=1 SV=2
2	O92956	4.41e-151	488	1603	0.334	0.199	POL_RSVSB Gag-Pol polyprotein OS=Rous sarcoma virus subgroup B (strain Schmidt-Ruppin) OX=269447 GN=gag-pol PE=1 SV=2
3	P03363	9.47e-95	330	1461	0.294	0.192	POL_HTLV2 Gag-Pro-Pol polyprotein OS=Human T-cell leukemia virus 2 OX=11909 GN=gag-pro-pol PE=1 SV=4
4	P03366	1.25e-64	240	1447	0.250	0.165	POL_HV1B1 Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate BH10) OX=11678 GN=gag-pol PE=1 SV=3
5	P04585	2.27e-64	239	1435	0.248	0.165	POL_HV1H2 Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) OX=11706 GN=gag-pol PE=1 SV=4
6	P35963	2.97e-63	236	1435	0.228	0.152	POL_HV1Y2 Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate YU-2) OX=362651 GN=gag-pol PE=1 SV=3
7	P12497	6.10e-61	229	1435	0.223	0.148	POL_HV1N5 Gag-Pol polyprotein OS=Human immunodeficiency virus type 1 group M subtype B (isolate NY5) OX=11698 GN=gag-pol PE=1 SV=4
8	P11204	2.20e-56	214	1146	0.164	0.137	POL_EIAV9 Pol polyprotein OS=Equine infectious anemia virus (isolate 1369) OX=11670 GN=pol PE=1 SV=1
9	Q72547	1.37e-48	184	566	0.176	0.297	Q72547_9HIV1 Reverse transcriptase/RNaseH (Fragment) OS=Human immunodeficiency virus 1 OX=11676 GN=pol PE=1 SV=1
10	A1Z651	4.45e-17	89.4	1733	0.154	0.085	POL_XMRV6 Gag-Pol polyprotein OS=Xenotropic MuLV-related virus (isolate VP62) OX=373193 GN=gag-pol PE=1 SV=1
11	P03355	4.80e-17	89.4	1738	0.096	0.053	POL_MLVMS Gag-Pol polyprotein OS=Moloney murine leukemia virus (isolate Shinnick) OX=928306 GN=gag-pol PE=1 SV=5
12	Q8UN00	2.18e-16	87.0	1738	0.085	0.047	Q8UN00_MLVMO Gag-Pol polyprotein OS=Moloney murine leukemia virus OX=11801 GN=gag-pro-pol PE=1 SV=1
13	P0CT40	2.84e-14	80.1	1333	0.072	0.052	TF29_SCHPO Transposon Tf2-9 polyprotein OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=Tf2-9 PE=3 SV=1
14	Q7LHG5	1.79e-12	74.3	1498	0.067	0.043	YI31B_YEAST Transposon Ty3-I Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TY3B-I PE=1 SV=2
15	Q99315	2.00e-12	73.9	1547	0.067	0.041	YG31B_YEAST Transposon Ty3-G Gag-Pol polyprotein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=TY3B-G PE=1 SV=3
16	Q76353	8.38e-11	66.2	288	0.073	0.243	Q76353_9HIV1 Integrase (Fragment) OS=Human immunodeficiency virus 1 OX=11676 PE=1 SV=1
17	P14350	2.50e-09	63.9	1143	0.090	0.075	POL_FOAMV Pro-Pol polyprotein OS=Human spumaretrovirus OX=11963 GN=pol PE=1 SV=2
18	P37007	6.61e-08	58.2	384	0.048	0.120	YAGA_ECOLI Uncharacterized protein YagA OS=Escherichia coli (strain K12) OX=83333 GN=yagA PE=2 SV=3
19	P9WKH9	0.002	43.5	278	0.038	0.129	TRA9_MYCTU Putative transposase for insertion sequence element IS986/IS6110 OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv0796 PE=4 SV=1
20	Q09633	0.003	43.9	507	0.047	0.089	Q09633_CAEEL RNase H type-1 domain-containing protein OS=Caenorhabditis elegans OX=6239 GN=rnh-1.1 PE=4 SV=3

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF13610 DDE_Tnp_IS240	17	17.1	DDE domain
2	PF02022 Integrase_Zn	3.3e-14	63.9	Integrase Zinc binding domain
3	PF00552 IN_DBD_C	0.00039	31.0	Integrase DNA binding domain
4	PF00075 RNase_H	4.7e-19	80.5	RNase H
5	PF00665 rve	1.5e-19	81.5	Integrase core domain
6	PF00078 RVT_1	1.2e-32	124.8	Reverse transcriptase (RNA-dependent DNA polymerase)
7	PF06817 RVT_thumb	8.3e-29	110.5	Reverse transcriptase thumb domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9978.XP_004580917.1

Rank	PPI partner	STRING score	Description
1	9978.XP_004584002.1	0.946	Corticosteroid 11-beta-dehydrogenase isozyme 2
2	9978.XP_004591918.1	0.945	Testosterone 17-beta-dehydrogenase 3
3	9978.XP_004580289.1	0.939	Steroid 17-alpha-hydroxylase/17,20 lyase-like
4	9978.XP_004598819.1	0.937	Steroid 21-hydroxylase-like
5	9978.XP_004578739.1	0.936	Corticosteroid 11-beta-dehydrogenase isozyme 1
6	9978.XP_004578134.1	0.934	Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 9 mRNAs, 4 Proteins
7	9978.XP_004597951.1	0.930	3-oxo-5-alpha-steroid 4-dehydrogenase 1
8	9978.XP_004582772.1	0.924	3-oxo-5-alpha-steroid 4-dehydrogenase 2
9	9978.XP_004590927.1	0.914	Polyprenol reductase isoform X1
10	9978.XP_004590320.1	0.910	Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 4 mRNAs, 9 Proteins
11	9978.XP_004588603.1	0.900	Aldo-keto reductase family 1 member C1 homolog
12	9978.XP_004585270.1	0.887	Adrenodoxin-like
13	9978.XP_004581915.1	0.850	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like isoform X1
14	9978.XP_004581917.1	0.850	Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 26 Proteins
15	9978.XP_004598566.1	0.785	Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 7 mRNAs, 10 Proteins
16	9978.XP_004584270.1	0.766	Estradiol 17-beta-dehydrogenase 2
17	9978.XP_004599780.1	0.766	Estradiol 17-beta-dehydrogenase 2-like
18	9978.XP_004588156.1	0.743	25-hydroxycholesterol 7-alpha-hydroxylase-like
19	9978.XP_004594430.1	0.731	3-oxo-5-beta-steroid 4-dehydrogenase-like isoform X1
20	9978.XP_004594433.1	0.731	Derived by automated computational analysis using gene prediction method: Gnomon. Supporting evidence includes similarity to: 3 mRNAs, 22 Proteins

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0042802	0.902	identical protein binding
GO:0003824	0.373	catalytic activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.989	cellular process
GO:0046483	0.984	heterocycle metabolic process
GO:0006725	0.984	cellular aromatic compound metabolic process
GO:0006807	0.980	nitrogen compound metabolic process
GO:1901360	0.980	organic cyclic compound metabolic process
GO:0006139	0.970	nucleobase-containing compound metabolic process
GO:0034654	0.587	nucleobase-containing compound biosynthetic process
GO:0006259	0.458	DNA metabolic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0110165	0.997	cellular anatomical entity
GO:0005622	0.986	intracellular anatomical structure
GO:0043229	0.907	intracellular organelle
GO:0043231	0.901	intracellular membrane-bounded organelle
GO:0005634	0.852	nucleus
GO:0005737	0.522	cytoplasm

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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