StarFunc result for job id Q9BXU1

User Input

>input (1019 residues)
MWVQGHSSRASATESVSFSGIVQMDEDTHYDKVEDVVGSHIEDAVTFWAQSINRNKDIMK
IGCSLSEVCPQASSVLGNLDPNKIYGGLFSEDQCWYRCKVLKIISVEKCLVRYIDYGNTE
ILNRSDIVEIPLELQFSSVAKKYKLWGLHIPSDQEVTQFDQGTTFLGSLIFEKEIKMRIK
ATSEDGTVIAQAEYGSVDIGEEVLKKGFAEKCRLASRTDICEEKKLDPGQLVLRNLKSPI
PLWGHRSNQSTFSRPKGHLSEKMTLDLKDENDAGNLITFPKESLAVGDFNLGSNVSLEKI
KQDQKLIEENEKLKTEKDALLESYKALELKVEQIAQELQQEKAAAVDLTNHLEYTLKTYI
DTRMKNLAAKMEILKEMRHVDISVRFGKDLSDAIQVLDEGCFTTPASLNGLEIIWAEYSL
AQENIKTCEYVSEGNILIAQRNEMQQKLYMSVEDFILEVDESSLNKRLKTLQDLSVSLEA
VYGQAKEGANSDEILKKFYDWKCDKREEFTSVRSETDASLHRLVAWFQRTLKVFDLSVEG
SLISEDAMDNIDEILEKTESSVCKELEIALVDQGDADKEIISNTYSQVLQKIHSEERLIA
TVQAKYKDSIEFKKQLIEYLNKSPSVDHLLSIKKTLKSLKALLRWKLVEKSNLEESDDPD
GSQIEKIKEEITQLRNNVFQEIYHEREEYEMLTSLAQKWFPELPLLHPEIGLLKYMNSGG
LLTMSLERDLLDAEPMKELSSKRPLVRSEVNGQIILLKGYSVDVDTEAKVIERAATYHRA
WREAEGDSGLLPLIFLFLCKSDPMAYLMVPYYPRANLNAVQANMPLNSEETLKVMKGVAQ
GLHTLHKADIIHGSLHQNNVFALNREQGIVGDFDFTKSVSQRASVNMMVGDLSLMSPELK
MGKPASPGSDLYAYGCLLLWLSVQNQEFEINKDGIPKVDQFHLDDKVKSLLCSLICYRSS
MTAEQVLNAECFLMPKEQSVPNPEKDTEYTLYKKEEEIKTENLDKCMEKTRNGEANFDC

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q99MW1	0.841	0.841	0.000	1018	0.780	0.781	Q99MW1.pdb.gz	STK31_MOUSE Serine/threonine-protein kinase 31 OS=Mus musculus OX=10090 GN=Stk31 PE=1 SV=2
2	AFDB:P61407	0.168	0.084	1.756E-12	2134	0.047	0.022	P61407.pdb.gz	TDRD6_MOUSE Tudor domain-containing protein 6 OS=Mus musculus OX=10090 GN=Tdrd6 PE=1 SV=1
3	AFDB:Q90WE3	0.153	0.084	4.515E-12	1905	0.049	0.026	Q90WE3.pdb.gz	TDRD6_XENLA Tudor domain-containing 6-like OS=Xenopus laevis OX=8355 GN=tdrd6 PE=1 SV=1
4	AFDB:Q9BXT4	0.172	0.149	5.508E-12	1180	0.054	0.047	Q9BXT4.pdb.gz	TDRD1_HUMAN Tudor domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TDRD1 PE=1 SV=2
5	AFDB:Q9Y2W6	0.177	0.311	2.447E-11	561	0.050	0.091	Q9Y2W6.pdb.gz	TDRKH_HUMAN Tudor and KH domain-containing protein OS=Homo sapiens OX=9606 GN=TDRKH PE=1 SV=2
6	AFDB:F1R237	0.169	0.083	3.297E-11	2117	0.051	0.025	F1R237.pdb.gz	TDRD6_DANRE Tudor domain-containing 6 OS=Danio rerio OX=7955 GN=tdrd6 PE=1 SV=2
7	AFDB:Q1XG89	0.164	0.097	6.291E-11	1759	0.046	0.027	Q1XG89.pdb.gz	TDR12_BOMMO Putative ATP-dependent RNA helicase TDRD12 OS=Bombyx mori OX=7091 GN=TDRD12 PE=1 SV=2
8	AFDB:Q5VCS6	0.160	0.157	4.828E-10	1040	0.045	0.044	Q5VCS6.pdb.gz	TDRD5_MOUSE Tudor domain-containing protein 5 OS=Mus musculus OX=10090 GN=Tdrd5 PE=1 SV=3
9	AFDB:Q99MV7	0.177	0.112	5.074E-10	1640	0.030	0.019	Q99MV7.pdb.gz	RNF17_MOUSE RING finger protein 17 OS=Mus musculus OX=10090 GN=Rnf17 PE=1 SV=2
10	AFDB:P25823	0.159	0.065	8.765E-10	2515	0.042	0.017	P25823.pdb.gz	TUD_DROME Maternal protein tudor OS=Drosophila melanogaster OX=7227 GN=tud PE=1 SV=2
11	PDB:6lk5A	0.190	0.627	6.129E-8	265	0.034	0.132	6lk5A.pdb.gz
12	PDB:4eomC	0.185	0.619	6.441E-8	276	0.043	0.159	4eomC.pdb.gz	An integrated chemical biology approach provides insight into Cdk2 functional redundancy and inhibitor sensitivity.
13	PDB:6byrA	0.195	0.450	6.769E-8	405	0.049	0.123	6byrA.pdb.gz	Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha.
14	PDB:7cgaA	0.174	0.470	8.679E-8	347	0.043	0.127	7cgaA.pdb.gz
15	PDB:2w96B	0.199	0.677	9.586E-8	267	0.046	0.176	2w96B.pdb.gz
16	PDB:4gcjA	0.184	0.546	1.007E-7	304	0.049	0.164	4gcjA.pdb.gz	Development of highly potent and selective diaminothiazole inhibitors of cyclin-dependent kinases.
17	PDB:5x3fB	0.191	0.500	1.113E-7	349	0.053	0.155	5x3fB.pdb.gz
18	PDB:4tthB	0.190	0.680	1.656E-7	256	0.047	0.188	4tthB.pdb.gz	Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.
19	PDB:2qkwB	0.144	0.453	2.345E-7	292	0.037	0.130	2qkwB.pdb.gz
20	PDB:5u6yA	0.181	0.374	2.345E-7	459	0.050	0.111	5u6yA.pdb.gz

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q99MW1	0.0	1639	1018	0.782	0.783	STK31_MOUSE Serine/threonine-protein kinase 31 OS=Mus musculus OX=10090 GN=Stk31 PE=1 SV=2
2	Q9BXT4	1.48e-07	58.2	1180	0.053	0.046	TDRD1_HUMAN Tudor domain-containing protein 1 OS=Homo sapiens OX=9606 GN=TDRD1 PE=1 SV=2
3	Q19328	3.20e-07	57.0	914	0.049	0.055	Q19328_CAEEL Staphylococcal nuclease domain-containing protein OS=Caenorhabditis elegans OX=6239 GN=tsn-1 PE=1 SV=1
4	Q9FL63	3.72e-07	56.6	614	0.036	0.060	Y5410_ARATH Inactive leucine-rich repeat receptor-like serine/threonine-protein kinase At5g24100 OS=Arabidopsis thaliana OX=3702 GN=At5g24100 PE=1 SV=1
5	O34507	4.14e-07	56.6	648	0.041	0.065	PRKC_BACSU Serine/threonine-protein kinase PrkC OS=Bacillus subtilis (strain 168) OX=224308 GN=prkC PE=1 SV=1
6	A0A1D5NSB4	7.10e-07	55.5	513	0.037	0.074	A0A1D5NSB4_DANRE Adhesion G protein-coupled receptor G1 OS=Danio rerio OX=7955 GN=si:dkey-181f22.4 PE=4 SV=1
7	Q91ZR4	8.87e-07	55.5	698	0.035	0.052	NEK8_MOUSE Serine/threonine-protein kinase Nek8 OS=Mus musculus OX=10090 GN=Nek8 PE=1 SV=1
8	Q8VQA0	9.72e-07	55.1	636	0.056	0.090	Q8VQA0_STRAG non-specific serine/threonine protein kinase OS=Streptococcus agalactiae OX=1311 GN=stk1 PE=4 SV=1
9	Q86SG6	1.18e-06	55.1	692	0.035	0.052	NEK8_HUMAN Serine/threonine-protein kinase Nek8 OS=Homo sapiens OX=9606 GN=NEK8 PE=1 SV=1
10	O80939	1.36e-06	54.7	675	0.041	0.062	LRK41_ARATH L-type lectin-domain containing receptor kinase IV.1 OS=Arabidopsis thaliana OX=3702 GN=LECRK41 PE=2 SV=1
11	C0LGF5	1.94e-06	54.7	1072	0.037	0.035	RGI5_ARATH LRR receptor-like serine/threonine-protein kinase RGI5 OS=Arabidopsis thaliana OX=3702 GN=RGI5 PE=1 SV=2
12	Q9M021	1.97e-06	54.3	682	0.037	0.056	LRK62_ARATH L-type lectin-domain containing receptor kinase VI.2 OS=Arabidopsis thaliana OX=3702 GN=LECRK62 PE=2 SV=1
13	Q9M020	2.20e-06	54.3	688	0.037	0.055	LRK63_ARATH Lectin-domain containing receptor kinase VI.3 OS=Arabidopsis thaliana OX=3702 GN=LECRK63 PE=2 SV=1
14	Q9W0S7	2.93e-06	53.9	926	0.044	0.049	SND1_DROME Staphylococcal nuclease domain-containing protein 1 OS=Drosophila melanogaster OX=7227 GN=Tudor-SN PE=1 SV=1
15	Q9LSS0	3.08e-06	53.5	668	0.048	0.073	LRK17_ARATH L-type lectin-domain containing receptor kinase I.7 OS=Arabidopsis thaliana OX=3702 GN=LECRK17 PE=2 SV=1
16	A0A0H2UVV3	3.18e-06	53.5	632	0.035	0.057	A0A0H2UVV3_STRP3 non-specific serine/threonine protein kinase OS=Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315) OX=198466 GN=SpyM3_1369 PE=1 SV=1
17	Q90WE3	3.51e-06	53.9	1905	0.064	0.034	TDRD6_XENLA Tudor domain-containing 6-like OS=Xenopus laevis OX=8355 GN=tdrd6 PE=1 SV=1
18	O43283	4.97e-06	53.1	966	0.031	0.033	M3K13_HUMAN Mitogen-activated protein kinase kinase kinase 13 OS=Homo sapiens OX=9606 GN=MAP3K13 PE=1 SV=1
19	Q2MHE4	4.97e-06	52.4	390	0.035	0.092	HT1_ARATH Serine/threonine/tyrosine-protein kinase HT1 OS=Arabidopsis thaliana OX=3702 GN=HT1 PE=1 SV=1
20	Q90XC2	5.95e-06	52.8	697	0.034	0.050	NEK8_DANRE Serine/threonine-protein kinase Nek8 OS=Danio rerio OX=7955 GN=nek8 PE=2 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF05641 Agenet	8.3	18.3	Agenet domain
2	PF00069 Pkinase	3e-14	64.6	Protein kinase domain
3	PF07714 PK_Tyr_Ser-Thr	9.2e-07	40.0	Protein tyrosine and serine/threonine kinase
4	PF00567 TUDOR	1.7e-20	84.7	Tudor domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000348132

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000245255	0.947	Piwi-like protein 1
2	9606.ENSP00000387303	0.882	ATP-dependent RNA helicase TDRD9
3	9606.ENSP00000406052	0.808	Tudor domain-containing protein 5
4	9606.ENSP00000384376	0.800	Tudor domain containing 15
5	9606.ENSP00000357812	0.751	Tudor and KH domain-containing protein
6	9606.ENSP00000347444	0.741	Tudor domain-containing protein 7
7	9606.ENSP00000478212	0.665	A-kinase anchor protein 1, mitochondrial
8	9606.ENSP00000371711	0.648	Doublesex- and mab-3-related transcription factor 1
9	9606.ENSP00000255324	0.644	RING finger protein 17
10	9606.ENSP00000334952	0.641	Adhesion G protein-coupled receptor A3
11	9606.ENSP00000390621	0.639	Putative ATP-dependent RNA helicase TDRD12
12	9606.ENSP00000357465	0.629	Tudor domain-containing protein 10
13	9606.ENSP00000266991	0.625	Desert hedgehog protein
14	9606.ENSP00000254900	0.618	Bromodomain-containing protein 8
15	9606.ENSP00000304192	0.611	Pecanex-like protein 1
16	9606.ENSP00000352678	0.608	ATP-dependent RNA helicase SUPV3L1, mitochondrial
17	9606.ENSP00000440190	0.600	Tudor domain-containing protein 3
18	9606.ENSP00000201031	0.579	Transcription factor AP-2 gamma
19	9606.ENSP00000305906	0.571	Undifferentiated embryonic cell transcription factor 1
20	9606.ENSP00000299001	0.566	Piwi-like protein 4

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0004672	1.000	protein kinase activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.993	cellular process
GO:0006807	0.981	nitrogen compound metabolic process
GO:0043170	0.980	macromolecule metabolic process
GO:0006468	0.969	protein phosphorylation
GO:0065007	0.736	biological regulation
GO:0050789	0.707	regulation of biological process
GO:0050794	0.489	regulation of cellular process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005737	1.000	cytoplasm
GO:0043231	1.000	intracellular membrane-bounded organelle
GO:0005634	0.957	nucleus
GO:0012505	0.932	endomembrane system
GO:0031410	0.887	cytoplasmic vesicle
GO:0030141	0.877	secretory granule
GO:0001669	0.869	acrosomal vesicle
GO:0031974	0.717	membrane-enclosed lumen
GO:0070013	0.714	intracellular organelle lumen
GO:0031981	0.684	nuclear lumen
GO:0005829	0.547	cytosol
GO:0005654	0.422	nucleoplasm
GO:0043232	0.398	intracellular non-membrane-bounded organelle

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name
EC:2.7.1.-	1.000	Phosphotransferases with an alcohol group as acceptor.

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