StarFunc result for job id Q9C019

User Input

>input (465 residues)
MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCPLC
QEEEQAETPMAPVPLGPLGETYCEEHGEKIYFFCENDAEFLCVFCREGPTHQAHTVGFLD
EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVETAFERLQQEL
EQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQPASELLQDVRV
NQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLEIDSGVITLDP
QTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHRWQVDLQLGDG
GGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCWASTSPGTDLPLSEIPRGVRVALD
YEAGQVTLHNAQTQEPIFTFTASFSGKVFPFFAVWKKGSCLTLKG

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q9C019	1.000	1.000	3.466E-83	465	1.000	1.000	Q9C019.pdb.gz	TRI15_HUMAN E3 ubiquitin-protein ligase TRIM15 OS=Homo sapiens OX=9606 GN=TRIM15 PE=1 SV=1
2	AFDB:Q9UDY6	0.374	0.364	7.745E-45	481	0.437	0.422	Q9UDY6.pdb.gz	TRI10_HUMAN Tripartite motif-containing protein 10 OS=Homo sapiens OX=9606 GN=TRIM10 PE=1 SV=3
3	AFDB:Q9WUH5	0.383	0.366	6.867E-44	489	0.434	0.413	Q9WUH5.pdb.gz	TRI10_MOUSE Tripartite motif-containing protein 10 OS=Mus musculus OX=10090 GN=Trim10 PE=2 SV=2
4	AFDB:Q99PN3	0.497	0.431	9.829E-40	545	0.368	0.314	Q99PN3.pdb.gz	TRI26_MOUSE Tripartite motif-containing protein 26 OS=Mus musculus OX=10090 GN=Trim26 PE=2 SV=3
5	AFDB:Q12899	0.488	0.427	1.538E-39	539	0.370	0.319	Q12899.pdb.gz	TRI26_HUMAN Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1
6	AFDB:Q923T7	0.417	0.384	3.010E-39	510	0.327	0.298	Q923T7.pdb.gz	TRIM7_MOUSE E3 ubiquitin-protein ligase TRIM7 OS=Mus musculus OX=10090 GN=Trim7 PE=2 SV=2
7	AFDB:Q9C029	0.413	0.380	8.716E-39	511	0.333	0.303	Q9C029.pdb.gz	TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 OS=Homo sapiens OX=9606 GN=TRIM7 PE=1 SV=2
8	AFDB:A0A1U9X8R9	0.418	0.384	8.106E-37	513	0.331	0.300	A0A1U9X8R9.pdb.gz	A0A1U9X8R9_HUMAN RING-type E3 ubiquitin transferase OS=Homo sapiens OX=9606 PE=4 SV=2
9	AFDB:Q5NCC9	0.353	0.339	9.352E-34	485	0.303	0.291	Q5NCC9.pdb.gz	TRI58_MOUSE E3 ubiquitin-protein ligase TRIM58 OS=Mus musculus OX=10090 GN=Trim58 PE=2 SV=1
10	AFDB:A0A024RCR1	0.368	0.351	1.384E-33	488	0.329	0.314	A0A024RCR1.pdb.gz
11	PDB:7y4sA	0.353	0.473	1.801E-17	343	0.161	0.219	7y4sA.pdb.gz
12	PDB:4b3nA	0.308	0.259	3.023E-12	557	0.095	0.079	4b3nA.pdb.gz	Structural Insight Into HIV-1 Capsid Recognition by Rhesus Trim5Alpha
13	PDB:7ccbA	0.275	0.717	3.459E-8	164	0.045	0.128	7ccbA.pdb.gz
14	PDB:7nscA	0.285	0.460	1.944E-6	276	0.047	0.080	7nscA.pdb.gz
15	PDB:4tn3B	0.310	0.386	6.296E-6	362	0.105	0.135	4tn3B.pdb.gz	Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice.
16	PDB:6swy1	0.266	0.231	1.541E-5	542	0.039	0.033	6swy1.pdb.gz
17	PDB:7nsba	0.222	0.185	3.017E-5	568	0.067	0.055	7nsba.pdb.gz
18	PDB:7z36B	0.247	0.256	3.774E-5	446	0.086	0.090	7z36B.pdb.gz	Structure and functional mapping of the KRAB-KAP1 repressor complex.
19	PDB:7m6aA	0.217	0.027	1.093E-4	4306	0.052	0.006	7m6aA.pdb.gz	High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
20	PDB:1umzA	0.220	0.350	3.958E-4	267	0.043	0.075	1umzA.pdb.gz	Crystal Structures of a Poplar Xyloglucan Endotransglycosylase Reveal Details of Transglycosylation Acceptor Binding

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q9C019	0.0	954	465	1.000	1.000	TRI15_HUMAN E3 ubiquitin-protein ligase TRIM15 OS=Homo sapiens OX=9606 GN=TRIM15 PE=1 SV=1
2	Q9UDY6	3.47e-128	382	481	0.441	0.426	TRI10_HUMAN Tripartite motif-containing protein 10 OS=Homo sapiens OX=9606 GN=TRIM10 PE=1 SV=3
3	Q9WUH5	4.56e-119	359	489	0.441	0.419	TRI10_MOUSE Tripartite motif-containing protein 10 OS=Mus musculus OX=10090 GN=Trim10 PE=2 SV=2
4	Q12899	5.97e-88	280	539	0.383	0.330	TRI26_HUMAN Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1
5	Q99PN3	5.89e-78	254	545	0.381	0.325	TRI26_MOUSE Tripartite motif-containing protein 26 OS=Mus musculus OX=10090 GN=Trim26 PE=2 SV=3
6	Q62158	1.66e-76	249	513	0.346	0.314	TRI27_MOUSE Zinc finger protein RFP OS=Mus musculus OX=10090 GN=Trim27 PE=1 SV=2
7	A0A1U9X8R9	7.25e-76	248	513	0.344	0.312	A0A1U9X8R9_HUMAN RING-type E3 ubiquitin transferase OS=Homo sapiens OX=9606 PE=4 SV=2
8	P14373	7.25e-76	248	513	0.344	0.312	TRI27_HUMAN Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1
9	Q923T7	4.78e-74	243	510	0.329	0.300	TRIM7_MOUSE E3 ubiquitin-protein ligase TRIM7 OS=Mus musculus OX=10090 GN=Trim7 PE=2 SV=2
10	Q9C029	6.12e-74	243	511	0.335	0.305	TRIM7_HUMAN E3 ubiquitin-protein ligase TRIM7 OS=Homo sapiens OX=9606 GN=TRIM7 PE=1 SV=2
11	A0A024RCP5	1.11e-69	232	518	0.325	0.292	A0A024RCP5_HUMAN TRIM39 OS=Homo sapiens OX=9606 PE=4 SV=1
12	Q9HCM9	1.11e-69	232	518	0.325	0.292	TRI39_HUMAN E3 ubiquitin-protein ligase TRIM39 OS=Homo sapiens OX=9606 GN=TRIM39 PE=1 SV=2
13	O00635	2.18e-67	224	465	0.312	0.312	TRI38_HUMAN E3 ubiquitin-protein ligase TRIM38 OS=Homo sapiens OX=9606 GN=TRIM38 PE=1 SV=1
14	Q8R0K2	1.29e-61	210	507	0.338	0.310	TRI31_MOUSE E3 ubiquitin-protein ligase TRIM31 OS=Mus musculus OX=10090 GN=Trim31 PE=1 SV=1
15	Q5NCC9	8.15e-61	207	485	0.314	0.301	TRI58_MOUSE E3 ubiquitin-protein ligase TRIM58 OS=Mus musculus OX=10090 GN=Trim58 PE=2 SV=1
16	P19474	2.52e-58	201	475	0.310	0.303	RO52_HUMAN E3 ubiquitin-protein ligase TRIM21 OS=Homo sapiens OX=9606 GN=TRIM21 PE=1 SV=1
17	F8W6Z2	5.71e-57	200	601	0.299	0.231	F8W6Z2_HUMAN MEFV innate immuity regulator, pyrin OS=Homo sapiens OX=9606 GN=MEFV PE=1 SV=1
18	Q6AZZ1	3.07e-56	196	485	0.301	0.289	TRI68_HUMAN E3 ubiquitin-protein ligase TRIM68 OS=Homo sapiens OX=9606 GN=TRIM68 PE=1 SV=1
19	Q99PQ2	3.82e-55	192	467	0.323	0.321	TRI11_MOUSE E3 ubiquitin-protein ligase TRIM11 OS=Mus musculus OX=10090 GN=Trim11 PE=1 SV=1
20	O15553	4.46e-55	198	781	0.323	0.192	MEFV_HUMAN Pyrin OS=Homo sapiens OX=9606 GN=MEFV PE=1 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF01442 Apolipoprotein	6.6e+02	11.5	Apolipoprotein A1/A4/E domain
2	PF04513 Baculo_PEP_C	9.9e+02	11.2	Baculovirus polyhedron envelope protein, PEP, C terminus
3	PF01544 CorA	3.6e+02	11.9	CorA-like Mg2+ transporter protein
4	PF07889 DUF1664	4.2e+02	12.4	Protein of unknown function (DUF1664)
5	PF12128 DUF3584	0.83	18.7	Protein of unknown function (DUF3584)
6	PF15397 DUF4618	33	15.3	Domain of unknown function (DUF4618)
7	PF02601 Exonuc_VII_L	1.8e+02	13.1	Exonuclease VII, large subunit
8	PF08702 Fib_alpha	42	15.7	Fibrinogen alpha/beta chain family
9	PF14447 Prok-RING_4	0.18	23.0	Prokaryotic RING finger family 4
10	PF13765 PRY	4.8e-16	69.4	SPRY-associated domain
11	PF00622 SPRY	5.4e-08	44.3	SPRY domain
12	PF00643 zf-B_box	7.6e-05	34.1	B-box zinc finger
13	PF00097 zf-C3HC4	0.0021	29.2	Zinc finger, C3HC4 type (RING finger)
14	PF13923 zf-C3HC4_2	0.15	23.2	Zinc finger, C3HC4 type (RING finger)
15	PF13920 zf-C3HC4_3	0.077	24.2	Zinc finger, C3HC4 type (RING finger)
16	PF15227 zf-C3HC4_4	0.0031	28.9	zinc finger of C3HC4-type, RING
17	PF13639 zf-RING_2	0.11	24.2	Ring finger domain
18	PF14634 zf-RING_5	0.29	22.4	zinc-RING finger domain
19	PF13445 zf-RING_UBOX	0.004	28.5	RING-type zinc-finger

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000365884

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000430493	0.642	CCR4-NOT transcription complex subunit 8
2	9606.ENSP00000267257	0.605	Paxillin
3	9606.ENSP00000295756	0.601	T-cell receptor-associated transmembrane adapter 1
4	9606.ENSP00000377471	0.589	Coronin-1B
5	9606.ENSP00000355279	0.561	CCR4-NOT transcription complex subunit 7
6	9606.ENSP00000384876	0.524	Tripartite motif-containing protein 66
7	9606.ENSP00000401980	0.515	Mitochondrial antiviral-signaling protein
8	9606.ENSP00000262294	0.511	E3 ubiquitin-protein ligase TRIM37
9	9606.ENSP00000394770	0.501	Cardiomyopathy-associated protein 5

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0003712	0.977	transcription coregulator activity
GO:0003713	0.955	transcription coactivator activity
GO:0042802	0.534	identical protein binding
GO:0003824	0.476	catalytic activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0050896	0.989	response to stimulus
GO:0050789	0.987	regulation of biological process
GO:0050794	0.984	regulation of cellular process
GO:0060255	0.980	regulation of macromolecule metabolic process
GO:0009987	0.976	cellular process
GO:0009605	0.974	response to external stimulus
GO:0002376	0.970	immune system process
GO:0048518	0.969	positive regulation of biological process
GO:0010468	0.963	regulation of gene expression
GO:0006950	0.958	response to stress
GO:0048519	0.951	negative regulation of biological process
GO:0045087	0.951	innate immune response
GO:1903900	0.947	regulation of viral life cycle
GO:0009615	0.943	response to virus
GO:0031323	0.937	regulation of cellular metabolic process
GO:0080090	0.936	regulation of primary metabolic process
GO:0051171	0.935	regulation of nitrogen compound metabolic process
GO:0048522	0.906	positive regulation of cellular process
GO:0048583	0.903	regulation of response to stimulus
GO:0051607	0.902	defense response to virus
GO:0051252	0.891	regulation of RNA metabolic process
GO:0048525	0.865	negative regulation of viral process
GO:0051091	0.864	positive regulation of DNA-binding transcription factor activity
GO:0001817	0.855	regulation of cytokine production
GO:0031347	0.807	regulation of defense response
GO:0009966	0.726	regulation of signal transduction
GO:0048856	0.687	anatomical structure development
GO:0032101	0.678	regulation of response to external stimulus
GO:0023056	0.632	positive regulation of signaling
GO:0048584	0.628	positive regulation of response to stimulus
GO:0002831	0.624	regulation of response to biotic stimulus
GO:0002682	0.597	regulation of immune system process
GO:1903901	0.597	negative regulation of viral life cycle
GO:0009967	0.580	positive regulation of signal transduction
GO:0008152	0.521	metabolic process
GO:0071704	0.495	organic substance metabolic process
GO:0009893	0.482	positive regulation of metabolic process
GO:0010604	0.473	positive regulation of macromolecule metabolic process
GO:0044238	0.462	primary metabolic process
GO:0050776	0.442	regulation of immune response
GO:0002684	0.440	positive regulation of immune system process
GO:0006807	0.429	nitrogen compound metabolic process
GO:0032501	0.425	multicellular organismal process
GO:0048523	0.419	negative regulation of cellular process
GO:0009892	0.382	negative regulation of metabolic process
GO:0043170	0.379	macromolecule metabolic process
GO:0030154	0.369	cell differentiation
GO:0051716	0.359	cellular response to stimulus
GO:0051240	0.356	positive regulation of multicellular organismal process
GO:0050778	0.356	positive regulation of immune response
GO:0010605	0.335	negative regulation of macromolecule metabolic process
GO:0001819	0.329	positive regulation of cytokine production

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005737	1.000	cytoplasm
GO:0005634	0.996	nucleus
GO:0005829	0.944	cytosol
GO:0016020	0.335	membrane

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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