StarFunc result for job id Q9GZS0

User Input

>input (605 residues)
MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAEQFVERNPVDTGIQCSISMSEH
EANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRKKVEKDENYVNAIMQLGSIMEHC
IKQNNAIDIYEEYFNDEEAMEVMEEDPSAKTINVFRDPQEIKRAATHLSWHPDGNRKLAV
AYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSSPLVTLEFNPKDSHVLLGGCYNGQ
IACWDTRKGSLVAELSTIESSHRDPVYGTIWLQSKTGTECFSASTDGQVMWWDIRKMSEP
TEVVILDITKKEQLENALGAISLEFESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTF
PGHHGPIYALQRNPFYPKNFLTVGDWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRP
TVFFTTRMDGTLDIWDFMFEQCDPTLSLKVCDEALFCLRVQDNGCLIACGSQLGTTTLLE
VSPGLSTLQRNEKNVASSMFERETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVD
LEALVSKAEEEFFDIIFAELKKKEADAIKLTPVPQQPSPEEDQVVEEGEEAAGEEGDEEV
EEDLA

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q9GZS0	1.000	1.000	0.000	605	1.000	1.000	Q9GZS0.pdb.gz	DNAI2_HUMAN Dynein axonemal intermediate chain 2 OS=Homo sapiens OX=9606 GN=DNAI2 PE=1 SV=2
2	AFDB:A2AC93	0.645	0.627	1.525E-100	623	0.850	0.825	A2AC93.pdb.gz	DNAI2_MOUSE Dynein axonemal intermediate chain 2 OS=Mus musculus OX=10090 GN=Dnai2 PE=1 SV=2
3	AFDB:Q4QR00	0.641	0.660	1.658E-92	587	0.679	0.700	Q4QR00.pdb.gz	DNAI2_XENLA Dynein axonemal intermediate chain 2 OS=Xenopus laevis OX=8355 GN=dnai2 PE=1 SV=1
4	AFDB:M9PC80	0.632	0.654	7.086E-73	585	0.443	0.458	M9PC80.pdb.gz	M9PC80_DROME Dynein, axonemal, intermediate chain 2, isoform C OS=Drosophila melanogaster OX=7227 GN=Dnai2 PE=4 SV=1
5	AFDB:P27766	0.689	0.732	9.396E-70	567	0.441	0.471	P27766.pdb.gz	DYI3_CHLRE Dynein, 70 kDa intermediate chain, flagellar outer arm OS=Chlamydomonas reinhardtii OX=3055 GN=ODA6 PE=1 SV=1
6	PDB:7kzmE	0.578	0.729	1.357E-42	474	0.388	0.496	7kzmE.pdb.gz	Structure of a microtubule-bound axonemal dynein.
7	AFDB:A8J3B6	0.572	0.346	5.088E-38	1024	0.230	0.136	A8J3B6.pdb.gz	A8J3B6_CHLRE Uncharacterized protein OS=Chlamydomonas reinhardtii OX=3055 GN=CHLRE_16g674515v5 PE=1 SV=1
8	AFDB:Q8IWG1	0.577	0.399	4.473E-37	891	0.236	0.160	Q8IWG1.pdb.gz	DNAI3_HUMAN Dynein axonemal intermediate chain 3 OS=Homo sapiens OX=9606 GN=DNAI3 PE=1 SV=1
9	AFDB:B2RY71	0.568	0.379	2.662E-36	923	0.260	0.170	B2RY71.pdb.gz	DNAI3_MOUSE Dynein axonemal intermediate chain 3 OS=Mus musculus OX=10090 GN=Dnai3 PE=1 SV=1
10	AFDB:E7F6H7	0.567	0.549	1.740E-34	626	0.185	0.179	E7F6H7.pdb.gz	DCI2A_DANRE Dynein, cytoplasmic 1, intermediate chain 2a OS=Danio rerio OX=7955 GN=dync1i2a PE=3 SV=2
11	AFDB:O88487	0.571	0.565	1.840E-34	612	0.188	0.186	O88487.pdb.gz	DC1I2_MOUSE Cytoplasmic dynein 1 intermediate chain 2 OS=Mus musculus OX=10090 GN=Dync1i2 PE=1 SV=1
12	PDB:7kzmD	0.540	0.708	2.593E-28	456	0.152	0.202	7kzmD.pdb.gz	Structure of a microtubule-bound axonemal dynein.
13	PDB:6rlbD	0.536	0.716	8.714E-24	446	0.169	0.229	6rlbD.pdb.gz
14	PDB:6f1tp	0.519	0.764	4.149E-23	401	0.154	0.232	6f1tp.pdb.gz	Cryo-EM shows how dynactin recruits two dyneins for faster movement.
15	PDB:7zgrD	0.450	0.672	6.997E-21	395	0.076	0.116	7zgrD.pdb.gz	Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF.
16	PDB:7mqaLQ	0.435	0.321	1.016E-19	830	0.083	0.060	7mqaLQ.pdb.gz	Nucleolar maturation of the human small subunit processome.
17	PDB:3jcmB	0.453	0.629	3.660E-19	429	0.081	0.114	3jcmB.pdb.gz	The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis
18	PDB:5yzgs	0.441	0.696	4.326E-19	374	0.088	0.142	5yzgs.pdb.gz	Structure of a human catalytic step I spliceosome
19	PDB:3w15A	0.457	0.792	4.574E-19	336	0.089	0.161	3w15A.pdb.gz	Crystal structure of peroxisomal targeting signal-2 bound to its receptor complex Pex7p-Pex21p
20	PDB:6zrdA	0.449	0.648	4.574E-19	411	0.078	0.114	6zrdA.pdb.gz	Structure Based Design of Bicyclic Peptide Inhibitors of RbAp48.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	A2AC93	0.0	1060	623	0.828	0.804	DNAI2_MOUSE Dynein axonemal intermediate chain 2 OS=Mus musculus OX=10090 GN=Dnai2 PE=1 SV=2
2	M9PC80	0.0	540	585	0.438	0.453	M9PC80_DROME Dynein, axonemal, intermediate chain 2, isoform C OS=Drosophila melanogaster OX=7227 GN=Dnai2 PE=4 SV=1
3	P27766	0.0	555	567	0.450	0.480	DYI3_CHLRE Dynein, 70 kDa intermediate chain, flagellar outer arm OS=Chlamydomonas reinhardtii OX=3055 GN=ODA6 PE=1 SV=1
4	Q4QR00	0.0	886	587	0.681	0.702	DNAI2_XENLA Dynein axonemal intermediate chain 2 OS=Xenopus laevis OX=8355 GN=dnai2 PE=1 SV=1
5	Q9GZS0	0.0	1260	605	1.000	1.000	DNAI2_HUMAN Dynein axonemal intermediate chain 2 OS=Homo sapiens OX=9606 GN=DNAI2 PE=1 SV=2
6	Q9VTM3	0.0	539	576	0.438	0.460	Q9VTM3_DROME Dynein, axonemal, intermediate chain 2, isoform B OS=Drosophila melanogaster OX=7227 GN=Dnai2 PE=4 SV=2
7	P54703	1.48e-33	138	654	0.174	0.161	DYIN_DICDI Cytoplasmic dynein 1 intermediate chain OS=Dictyostelium discoideum OX=44689 GN=dicA PE=2 SV=2
8	A0A286ZPL5	7.50e-33	136	704	0.177	0.152	A0A286ZPL5_PIG Dynein axonemal intermediate chain 1 OS=Sus scrofa OX=9823 GN=DNAI1 PE=4 SV=2
9	Q385R8	4.79e-32	133	655	0.165	0.153	Q385R8_TRYB2 Dynein intermediate chain, putative OS=Trypanosoma brucei brucei (strain 927/4 GUTat10.1) OX=185431 GN=Tb11.02.2640 PE=4 SV=1
10	Q5XIL8	2.15e-31	132	705	0.167	0.143	DNAI1_RAT Dynein axonemal intermediate chain 1 OS=Rattus norvegicus OX=10116 GN=Dnai1 PE=1 SV=1
11	Q8C0M8	7.42e-31	130	701	0.167	0.144	DNAI1_MOUSE Dynein axonemal intermediate chain 1 OS=Mus musculus OX=10090 GN=Dnai1 PE=1 SV=1
12	Q9UI46	8.37e-31	130	699	0.162	0.140	DNAI1_HUMAN Dynein axonemal intermediate chain 1 OS=Homo sapiens OX=9606 GN=DNAI1 PE=1 SV=1
13	Q24246	8.21e-29	124	663	0.175	0.160	DYIN_DROME Cytoplasmic dynein 1 intermediate chain OS=Drosophila melanogaster OX=7227 GN=sw PE=1 SV=3
14	A0A0D9RCF4	1.57e-28	123	693	0.155	0.136	A0A0D9RCF4_CHLSB Dynein axonemal intermediate chain 1 OS=Chlorocebus sabaeus OX=60711 GN=DNAI1 PE=4 SV=1
15	Q5BDC6	3.15e-27	119	689	0.145	0.128	Q5BDC6_EMENI Cytoplasmic dynein intermediate chain OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=nudI PE=4 SV=1
16	Q39578	6.28e-27	118	683	0.154	0.136	DYI2_CHLRE Dynein, 78 kDa intermediate chain, flagellar outer arm OS=Chlamydomonas reinhardtii OX=3055 GN=ODA9 PE=1 SV=3
17	Q5U4F6	3.49e-26	115	537	0.164	0.184	DC2I2_MOUSE Cytoplasmic dynein 2 intermediate chain 2 OS=Mus musculus OX=10090 GN=Dync2i2 PE=1 SV=3
18	E7F6H7	9.25e-26	114	626	0.149	0.144	DCI2A_DANRE Dynein, cytoplasmic 1, intermediate chain 2a OS=Danio rerio OX=7955 GN=dync1i2a PE=3 SV=2
19	B2RY71	4.89e-25	112	923	0.137	0.090	DNAI3_MOUSE Dynein axonemal intermediate chain 3 OS=Mus musculus OX=10090 GN=Dnai3 PE=1 SV=1
20	Q96EX3	1.15e-24	110	536	0.167	0.188	DC2I2_HUMAN Cytoplasmic dynein 2 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC2I2 PE=1 SV=2

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF12894 ANAPC4_WD40	9.9	17.9	Anaphase-promoting complex subunit 4 WD40 domain
2	PF16043 DUF4795	0.57	21.2	Domain of unknown function (DUF4795)
3	PF00400 WD40	2.4	20.3	WD domain, G-beta repeat

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000400252

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000265104	0.983	Dynein heavy chain 5, axonemal
2	9606.ENSP00000354791	0.976	Dynactin subunit 1
3	9606.ENSP00000318429	0.952	Coiled-coil domain-containing protein 114
4	9606.ENSP00000296218	0.914	Axonemal dynein light intermediate polypeptide 1
5	9606.ENSP00000298292	0.913	Protein kintoun
6	9606.ENSP00000333363	0.913	Dynein heavy chain 8, axonemal
7	9606.ENSP00000199447	0.906	Thioredoxin domain-containing protein 3
8	9606.ENSP00000452037	0.900	Dynein light chain 1, axonemal
9	9606.ENSP00000367815	0.898	Dynein assembly factor 1, axonemal
10	9606.ENSP00000401514	0.898	Dynein heavy chain 1, axonemal
11	9606.ENSP00000374490	0.887	Dynein heavy chain 17, axonemal
12	9606.ENSP00000262442	0.885	Dynein heavy chain 9, axonemal
13	9606.ENSP00000408910	0.880	Dynactin subunit 2
14	9606.ENSP00000391692	0.869	Coiled-coil domain containing 103
15	9606.ENSP00000391869	0.869	annotation not available
16	9606.ENSP00000475939	0.861	Dynein heavy chain 11, axonemal
17	9606.ENSP00000300087	0.856	Dynactin subunit 5
18	9606.ENSP00000297440	0.848	Dynein assembly factor 5, axonemal
19	9606.ENSP00000458355	0.847	Dynein heavy chain 2, axonemal
20	9606.ENSP00000229554	0.846	Radial spoke head protein 4 homolog A

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding
GO:0003774	0.442	cytoskeletal motor activity
GO:0003777	0.384	microtubule motor activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0007017	0.996	microtubule-based process
GO:0070286	0.993	axonemal dynein complex assembly
GO:0007018	0.985	microtubule-based movement
GO:0007275	0.985	multicellular organism development
GO:0003341	0.973	cilium movement
GO:0060972	0.927	left/right pattern formation
GO:0009799	0.921	specification of symmetry
GO:0009855	0.907	determination of bilateral symmetry
GO:0007368	0.904	determination of left/right symmetry
GO:0050789	0.392	regulation of biological process
GO:0050794	0.364	regulation of cellular process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005737	1.000	cytoplasm
GO:0043232	1.000	intracellular non-membrane-bounded organelle
GO:0005929	0.997	cilium
GO:0005856	0.994	cytoskeleton
GO:0031514	0.985	motile cilium
GO:0005930	0.976	axoneme
GO:0032991	0.969	protein-containing complex
GO:0097729	0.917	9+2 motile cilium
GO:0015630	0.906	microtubule cytoskeleton
GO:0005875	0.843	microtubule associated complex
GO:1902494	0.658	catalytic complex
GO:0036126	0.377	sperm flagellum
GO:0005858	0.345	axonemal dynein complex

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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