StarFunc result for job id Q9H195

User Input

>input (1237 residues)
MQLLGLLSILWMLKSSPGATGTLSTATSTSHVTFPRAEATRTALSNSPHSRYLAEWPQGV
PQLASPAPGHRENAPMTLTTSPHDTLISETLLSSLVSSNTSTTPTSKFAFKVETTPPTVL
VYSATTECVYPTSFIITISHSTSICVTTTQVTFTSSYTPTPVTQKPVTTVTRTYPMTTTE
KGTSAMISSPSTTTARETPIVTVTPSSSVSATDTTFHTTISSTTRTTERTPLPTGSIHTT
MSPTPVFTTLKTAVTSTSPITSTITSTNTVTSMTTTTSRPTATNTLSSLTSSILSSTPAP
NTEVITSHTTTTTPPSTLVTTLPTAIARSTPTSETTPSFMSSIITTETTSHSTPSFSSST
IHSTVSSSTTAITSPFTTAETGVTSTPSSPSSLSTDIPTTSLRTLTPLSLSTSTSLTTTT
DLPSIPTDISSLPTPIHIISSSPSIQSTETSSLVGTTSPTMSTVRATLRSTENTPISSFS
TSIVVTPETPTTQAPPVLMSATGTQTSPVPTTVTFGSMDSSTSTLHTLTPSTALSKIMST
SQFPIPSTHSSTLQTTPSIPSLQTSLTSTSEFTTESFTRGSTSTNAILTSFSTIIWSSTP
TIIMSSSPSSASITPVFATTIHSVPSSPYIFSTENVGSASITAFPSLSSSSTTSTSPTSS
SLTTALTEITPFSYISLPSTTPCPGTITITIVPASPTDPCVEMDPSTEATSPPTTPLTVF
PFTTEMVTCPSSISMQTTLATHMDTSSMTPESESSIIPNASSSTGTGTVPTNTVFTSTRL
PTSETWLSNNSVIPTPLPGVSTIPLTMKPSSSLPTILRTSSKSTHPSPPTARTSQTSVAT
TQTPTTLTTCRTTPITSWMTTQSTLTTTAGTCDNGGTWEQGQCACLPGFSGDRCQLQTRC
QNGGQWDGLKCQCPSTFYGSSCEFAVEQVDLDVVETEVGMEVSVDQQFSPDLNDNTSQAY
RDFNKTFWNQMQKIFADMQGFTFKGVEILSLRNGSIVVDYLVLLEMPFSPQLESEYEQVK
TTLKEGLQNASQDANSCQDSQALCFKPDSIKVNNNSKTELTPEAICRRAAPTGYEEFYFP
LVEATRLRCVTKCTSGLDNAIDCHQGQCVLETSGPACRCYSTDTHWFSGPRCEVTVHWRA
LVGGLTAGAALLVLLLLALGVRAVRSEWWGRQRRGRSWDQDRKWFETWDEEVVGTFSNWG
FEDDGTDKDTNFHVALENVDTTMKVHIKRPEMTSSSV

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q9H195	1.000	1.000	0.000	1237	1.000	1.000	Q9H195.pdb.gz	MUC3B_HUMAN Mucin-3B OS=Homo sapiens OX=9606 GN=MUC3B PE=2 SV=3
2	AFDB:A1Z6W9	0.123	0.113	3.984E-11	1363	0.159	0.145	A1Z6W9.pdb.gz	A1Z6W9_DROME Pawn, isoform B OS=Drosophila melanogaster OX=7227 GN=pwn PE=4 SV=2
3	AFDB:E9Q7X6	0.088	0.084	7.908E-10	1337	0.174	0.161	E9Q7X6.pdb.gz	HEG1_MOUSE Protein HEG homolog 1 OS=Mus musculus OX=10090 GN=Heg1 PE=1 SV=1
4	AFDB:Q6R8J2	0.086	0.104	5.268E-9	977	0.129	0.164	Q6R8J2.pdb.gz	HEG_DANRE Protein HEG OS=Danio rerio OX=7955 GN=heg PE=1 SV=1
5	AFDB:Q6FTU1	0.081	0.102	6.936E-6	936	0.134	0.177	Q6FTU1.pdb.gz	Q6FTU1_CANGA Candida glabrata strain CBS138 chromosome F complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=CAGL0F08833g PE=4 SV=1
6	AFDB:P32334	0.076	0.073	3.672E-5	1306	0.195	0.185	P32334.pdb.gz	MSB2_YEAST Signaling mucin MSB2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) OX=559292 GN=MSB2 PE=1 SV=1
7	AFDB:A0A1D8PGF8	0.072	0.064	3.078E-4	1409	0.209	0.184	A0A1D8PGF8.pdb.gz	A0A1D8PGF8_CANAL Msb2p OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=MSB2 PE=4 SV=1
8	AFDB:Q6FUJ4	0.072	0.075	7.288E-4	1185	0.169	0.176	Q6FUJ4.pdb.gz	Q6FUJ4_CANGA Candida glabrata strain CBS138 chromosome F complete sequence OS=Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) OX=284593 GN=CAGL0F03003g PE=4 SV=1
9	AFDB:A0A2R8QK78	0.076	0.065	8.175E-4	1570	0.154	0.121	A0A2R8QK78.pdb.gz
10	PDB:5etlD	0.057	0.295	6.628E-3	160	0.010	0.075	5etlD.pdb.gz	Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli.
11	AFDB:Q68FD9	0.063	0.045	1.446E-2	1940	0.179	0.114	Q68FD9.pdb.gz	K1549_MOUSE UPF0606 protein KIAA1549 OS=Mus musculus OX=10090 GN=Kiaa1549 PE=1 SV=3
12	PDB:1vixA	0.060	0.152	2.953E-2	411	0.007	0.022	1vixA.pdb.gz	Structural analysis of a set of proteins resulting from a bacterial genomics project
13	PDB:7a5fE6	0.052	0.273	3.509E-2	122	0.011	0.115	7a5fE6.pdb.gz	Elongational stalling activates mitoribosome-associated quality control.
14	PDB:3jd5F	0.058	0.300	3.716E-2	124	0.010	0.097	3jd5F.pdb.gz	Cryo-EM structure of the small subunit of the mammalian mitochondrial ribosome.
15	PDB:5mrcFF	0.056	0.305	4.169E-2	125	0.015	0.144	5mrcFF.pdb.gz	The structure of the yeast mitochondrial ribosome.
16	PDB:7mpyB	0.056	0.129	5.556E-2	430	0.008	0.023	7mpyB.pdb.gz
17	PDB:7pntE	0.043	0.224	5.556E-2	122	0.007	0.074	7pntE.pdb.gz	Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
18	PDB:7r5jH0	0.052	0.130	5.885E-2	383	0.017	0.055	7r5jH0.pdb.gz	AI-based structure prediction empowers integrative structural analysis of human nuclear pores
19	PDB:2zofA	0.052	0.115	6.602E-2	478	0.023	0.059	2zofA.pdb.gz	Structural basis for substrate recognition and hydrolysis by mouse carnosinase CN2.
20	PDB:7o37A	0.043	0.093	7.844E-2	446	0.011	0.029	7o37A.pdb.gz	Structure and assembly of the mammalian mitochondrial supercomplex CIII 2 CIV.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	Q02505	0.0	1471	3323	0.665	0.247	MUC3A_HUMAN Mucin-3A OS=Homo sapiens OX=9606 GN=MUC3A PE=1 SV=3
2	Q9H195	0.0	2410	1237	1.000	1.000	MUC3B_HUMAN Mucin-3B OS=Homo sapiens OX=9606 GN=MUC3B PE=2 SV=3
3	Q685J3	5.31e-70	261	4493	0.092	0.025	MUC17_HUMAN Mucin-17 OS=Homo sapiens OX=9606 GN=MUC17 PE=1 SV=2
4	E9PWP7	3.56e-64	243	4499	0.113	0.031	E9PWP7_MOUSE Mucin 3, intestinal OS=Mus musculus OX=10090 GN=Muc17 PE=1 SV=4
5	Q91WF4	5.15e-61	216	391	0.114	0.361	Q91WF4_MOUSE Muc3 protein (Fragment) OS=Mus musculus OX=10090 GN=Muc17 PE=2 SV=1
6	O35419	3.45e-59	213	442	0.112	0.312	O35419_MOUSE Mucin glycoprotein MUC3 (Fragment) OS=Mus musculus OX=10090 GN=Muc17 PE=2 SV=1
7	Q9UKN1	1.10e-53	209	5478	0.091	0.020	MUC12_HUMAN Mucin-12 OS=Homo sapiens OX=9606 GN=MUC12 PE=1 SV=2
8	Q8R0K3	4.48e-43	162	336	0.093	0.342	Q8R0K3_MOUSE Muc3 protein (Fragment) OS=Mus musculus OX=10090 GN=Muc17 PE=2 SV=1
9	Q80Y91	7.75e-37	143	305	0.080	0.325	Q80Y91_MOUSE Muc3 protein (Fragment) OS=Mus musculus OX=10090 GN=Muc17 PE=2 SV=1
10	Q3UWC5	2.75e-15	77.4	175	0.041	0.291	Q3UWC5_MOUSE Uncharacterized protein (Fragment) OS=Mus musculus OX=10090 GN=Muc17 PE=2 SV=1
11	Q99102	3.02e-08	61.2	5412	0.056	0.013	MUC4_HUMAN Mucin-4 OS=Homo sapiens OX=9606 GN=MUC4 PE=1 SV=5
12	Q07954	1.37e-06	55.5	4544	0.029	0.008	LRP1_HUMAN Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens OX=9606 GN=LRP1 PE=1 SV=2
13	Q06806	2.94e-06	54.3	1134	0.021	0.023	TIE1_MOUSE Tyrosine-protein kinase receptor Tie-1 OS=Mus musculus OX=10090 GN=Tie1 PE=1 SV=3
14	B5DFD6	3.14e-06	54.3	1137	0.021	0.023	B5DFD6_RAT receptor protein-tyrosine kinase OS=Rattus norvegicus OX=10116 GN=Tie1 PE=2 SV=1
15	P35590	3.15e-06	54.3	1138	0.021	0.023	TIE1_HUMAN Tyrosine-protein kinase receptor Tie-1 OS=Homo sapiens OX=9606 GN=TIE1 PE=1 SV=1
16	E1BGJ0	4.48e-06	53.9	4545	0.028	0.008	E1BGJ0_BOVIN LDL receptor related protein 1 OS=Bos taurus OX=9913 GN=LRP1 PE=1 SV=3
17	Q91ZX7	8.63e-06	53.1	4545	0.028	0.008	LRP1_MOUSE Prolow-density lipoprotein receptor-related protein 1 OS=Mus musculus OX=10090 GN=Lrp1 PE=1 SV=1
18	G3V928	8.93e-06	52.8	4545	0.028	0.008	LRP1_RAT Prolow-density lipoprotein receptor-related protein 1 OS=Rattus norvegicus OX=10116 GN=Lrp1 PE=1 SV=1
19	Q75ZI3	1.77e-05	52.0	1570	0.028	0.022	Q75ZI3_DANRE Dermacan OS=Danio rerio OX=7955 GN=dcan PE=1 SV=1
20	Q9WUA1	2.54e-05	50.4	379	0.020	0.066	WIF1_MOUSE Wnt inhibitory factor 1 OS=Mus musculus OX=10090 GN=Wif1 PE=2 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF07974 EGF_2	5.2e+02	12.4	EGF-like domain
2	PF01390 SEA	1.8e-08	45.9	SEA domain

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9593.ENSGGOP00000027458

Rank	PPI partner	STRING score	Description
1	9593.ENSGGOP00000020248	0.787	Mucin 15, cell surface associated
2	9593.ENSGGOP00000013247	0.783	Mucin 20, cell surface associated
3	9593.ENSGGOP00000020498	0.781	Mucin 6, oligomeric mucus/gel-forming
4	9593.ENSGGOP00000000418	0.780	Mucin 13, cell surface associated
5	9593.ENSGGOP00000012583	0.780	Mucin 7, secreted
6	9593.ENSGGOP00000023492	0.780	Uncharacterized protein
7	9593.ENSGGOP00000012034	0.770	Mucin 5B, oligomeric mucus/gel-forming
8	9593.ENSGGOP00000028722	0.768	Polypeptide N-acetylgalactosaminyltransferase 13
9	9593.ENSGGOP00000009103	0.767	Mucin 1, cell surface associated
10	9593.ENSGGOP00000021891	0.767	Uncharacterized protein
11	9593.ENSGGOP00000021218	0.763	Mucin 21, cell surface associated
12	9593.ENSGGOP00000020693	0.761	Uncharacterized protein
13	9593.ENSGGOP00000006693	0.717	Polypeptide N-acetylgalactosaminyltransferase 1
14	9593.ENSGGOP00000021211	0.690	Uncharacterized protein
15	9593.ENSGGOP00000004468	0.661	alpha-1,4-N-acetylglucosaminyltransferase
16	9593.ENSGGOP00000019030	0.650	Glucosaminyl (N-acetyl) transferase 4, core 2
17	9593.ENSGGOP00000016412	0.625	Uncharacterized protein
18	9593.ENSGGOP00000012148	0.596	Uncharacterized protein
19	9593.ENSGGOP00000002726	0.581	Polypeptide N-acetylgalactosaminyltransferase-like 6
20	9593.ENSGGOP00000014083	0.581	Polypeptide N-acetylgalactosaminyltransferase 10

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0005515	1.000	protein binding

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0008150	1.000	biological_process
GO:0009987	0.806	cellular process
GO:0050789	0.546	regulation of biological process
GO:0050794	0.484	regulation of cellular process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005886	1.000	plasma membrane
GO:0005796	0.998	Golgi lumen

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name

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