StarFunc result for job id Q9H1B5

User Input

>input (865 residues)
MVASARVQKLVRRYKLAIATALAILLLQGLVVWSFSGLEEDEAGEKGRQRKPRPLDPGEG
SKDTDSSAGRRGSTGRRHGRWRGRAESPGVPVAKVVRAVTSRQRASRRVPPAPPPEAPGR
QNLSGAAAGEALVGAAGFPPHGDTGSVEGAPQPTDNGFTPKCEIVGKDALSALARASTKQ
CQQEIANVVCLHQAGSLMPKAVPRHCQLTGKMSPGIQWDESQAQQPMDGPPVRIAYMLVV
HGRAIRQLKRLLKAVYHEQHFFYIHVDKRSDYLHREVVELAQGYDNVRVTPWRMVTIWGG
ASLLRMYLRSMRDLLEVPGWAWDFFINLSATDYPTRTNEELVAFLSKNRDKNFLKSHGRD
NSRFIKKQGLDRLFHECDSHMWRLGERQIPAGIVVDGGSDWFVLTRSFVEYVVYTDDPLV
AQLRQFYTYTLLPAESFFHTVLENSLACETLVDNNLRVTNWNRKLGCKCQYKHIVDWCGC
SPNDFKPQDFLRLQQVSRPTFFARKFESTVNQEVLEILDFHLYGSYPPGTPALKAYWENT
YDAADGPSGLSDVMLTAYTAFARLSLHHAATAAPPMGTPLCRFEPRGLPSSVHLYFYDDH
FQGYLVTQAVQPSAQGPAETLEMWLMPQGSLKLLGRSDQASRLQSLEVGTDWDPKERLFR
NFGGLLGPLDEPVAVQRWARGPNLTATVVWIDPTYVVATSYDITVDTETEVTQYKPPLSR
PLRPGPWTVRLLQFWEPLGETRFLVLPLTFNRKLPLRKDDASWLHAGPPHNEYMEQSFQG
LSSILNLPQPELAEEAAQRHTQLTGPALEAWTDRELSSFWSVAGLCAIGPSPCPSLEPCR
LTSWSSLSPDPKSELGPVKADGRLR

Proteins with similar structure

Top structural analogs (as identified by Foldseek and TM-align)

Rank	Structure template	TM-score1	TM-score2	Foldseek E-value	Length	ID1	ID2	Download	Description
1	AFDB:Q811B1	0.821	0.746	0.000	953	0.540	0.490	Q811B1.pdb.gz	XYLT1_MOUSE Xylosyltransferase 1 OS=Mus musculus OX=10090 GN=Xylt1 PE=1 SV=1
2	AFDB:Q86Y38	0.820	0.740	0.000	959	0.564	0.509	Q86Y38.pdb.gz	XYLT1_HUMAN Xylosyltransferase 1 OS=Homo sapiens OX=9606 GN=XYLT1 PE=1 SV=1
3	AFDB:Q9EPL0	0.983	0.983	0.000	865	0.935	0.935	Q9EPL0.pdb.gz	XYLT2_MOUSE Xylosyltransferase 2 OS=Mus musculus OX=10090 GN=Xylt2 PE=2 SV=3
4	AFDB:Q7KVA1	0.744	0.734	2.556E-80	876	0.355	0.350	Q7KVA1.pdb.gz	XYLT_DROME Xylosyltransferase oxt OS=Drosophila melanogaster OX=7227 GN=oxt PE=2 SV=1
5	AFDB:Q965Q8	0.645	0.691	5.896E-52	806	0.221	0.237	Q965Q8.pdb.gz	XYLT_CAEEL Xylosyltransferase sqv-6 OS=Caenorhabditis elegans OX=6239 GN=sqv-6 PE=1 SV=3
6	AFDB:O95395	0.285	0.543	3.036E-19	438	0.084	0.167	O95395.pdb.gz	GCNT3_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 OS=Homo sapiens OX=9606 GN=GCNT3 PE=2 SV=1
7	AFDB:Q6T5D9	0.292	0.602	4.239E-19	400	0.086	0.185	Q6T5D9.pdb.gz	Q6T5D9_RAT Glucosaminyl (N-acetyl) transferase 2 (I blood group) OS=Rattus norvegicus OX=10116 GN=Gcnt2 PE=2 SV=1
8	AFDB:Q5JCT0	0.286	0.547	6.615E-19	437	0.086	0.169	Q5JCT0.pdb.gz	GCNT3_MOUSE Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 OS=Mus musculus OX=10090 GN=Gcnt3 PE=2 SV=2
9	AFDB:Q9P109	0.281	0.517	1.363E-18	453	0.090	0.172	Q9P109.pdb.gz	GCNT4_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 OS=Homo sapiens OX=9606 GN=GCNT4 PE=2 SV=1
10	AFDB:E9Q649	0.277	0.506	1.904E-18	455	0.084	0.160	E9Q649.pdb.gz	GCNT4_MOUSE Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 OS=Mus musculus OX=10090 GN=Gcnt4 PE=3 SV=1
11	PDB:2gamC	0.287	0.638	2.811E-18	374	0.088	0.203	2gamC.pdb.gz	X-ray Crystal Structure of Leukocyte Type Core 2 beta1,6-N-Acetylglucosaminyltransferase: Evidence for a covergence of metal ion independent glycosyltransferase mechanism.
12	PDB:6fxrA	0.146	0.171	2.956E-5	700	0.080	0.099	6fxrA.pdb.gz	Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3.
13	PDB:4d0tA	0.142	0.235	1.063E-4	496	0.037	0.065	4d0tA.pdb.gz	Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N-Acetylgalactosaminyltransferase 2.
14	PDB:7jhiC	0.189	0.428	3.058E-4	331	0.034	0.088	7jhiC.pdb.gz	Structures and mechanism of human glycosyltransferase beta 1,3-N-acetylglucosaminyltransferase 2 (B3GNT2), an important player in immune homeostasis.
15	PDB:5mlzA	0.129	0.274	3.613E-4	355	0.036	0.087	5mlzA.pdb.gz	Structural basis for dolichylphosphate mannose biosynthesis.
16	PDB:4d11C	0.146	0.272	5.638E-4	436	0.044	0.087	4d11C.pdb.gz	Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N- Acetylgalactosaminyltransferase 2.
17	PDB:7x8kB	0.145	0.307	7.446E-4	367	0.032	0.076	7x8kB.pdb.gz	Crystal Structures of Arabidopsis thaliana GDP-D-Mannose Pyrophosphorylase VITAMIN C DEFECTIVE 1.
18	PDB:2d7iA	0.143	0.220	8.322E-4	536	0.054	0.088	2d7iA.pdb.gz	Structural basis of carbohydrate transfer activity by human UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase (pp-GalNAc-T10)
19	PDB:2i5kB	0.194	0.316	1.228E-3	466	0.047	0.088	2i5kB.pdb.gz
20	PDB:7msnA	0.113	0.215	1.299E-3	417	0.022	0.046	7msnA.pdb.gz	Structural and mechanistic investigations of protein S-glycosyltransferases.

(a)	The query structure is shown in cartoon, while the structural analog is displayed using a backbone trace.
(b)	Ranking of proteins is based on E-value of Foldseek alignment.
(c)	TM-score1 and ID1 are TM-score and sequence identity normalized by query sequence length.
(d)	TM-score2 and ID2 are TM-score and sequence identity normalized by template sequence length.

Proteins with similar sequence

Top sequence homologs in UniProt

Rank	Template	E-value	Bit-score	Length	ID1	ID2	Description
1	D3J0E7	0.0	940	919	0.503	0.473	D3J0E7_DANRE protein xylosyltransferase OS=Danio rerio OX=7955 GN=xylt1 PE=2 SV=1
2	Q811B1	0.0	928	953	0.495	0.449	XYLT1_MOUSE Xylosyltransferase 1 OS=Mus musculus OX=10090 GN=Xylt1 PE=1 SV=1
3	Q86Y38	0.0	956	959	0.517	0.466	XYLT1_HUMAN Xylosyltransferase 1 OS=Homo sapiens OX=9606 GN=XYLT1 PE=1 SV=1
4	Q9EPI1	0.0	944	821	0.508	0.535	XYLT1_RAT Xylosyltransferase 1 (Fragment) OS=Rattus norvegicus OX=10116 GN=Xylt1 PE=2 SV=1
5	Q9EPL0	0.0	1627	865	0.935	0.935	XYLT2_MOUSE Xylosyltransferase 2 OS=Mus musculus OX=10090 GN=Xylt2 PE=2 SV=3
6	Q9H1B5	0.0	1786	865	1.000	1.000	XYLT2_HUMAN Xylosyltransferase 2 OS=Homo sapiens OX=9606 GN=XYLT2 PE=1 SV=2
7	Q7KVA1	1.10e-155	480	876	0.311	0.307	XYLT_DROME Xylosyltransferase oxt OS=Drosophila melanogaster OX=7227 GN=oxt PE=2 SV=1
8	Q965Q8	1.32e-77	270	806	0.146	0.156	XYLT_CAEEL Xylosyltransferase sqv-6 OS=Caenorhabditis elegans OX=6239 GN=sqv-6 PE=1 SV=3
9	Q9SS69	1.88e-20	96.7	378	0.101	0.230	Q9SS69_ARATH Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein OS=Arabidopsis thaliana OX=3702 GN=UNE7 PE=1 SV=1
10	F4JIW2	8.71e-20	95.1	421	0.088	0.181	F4JIW2_ARATH Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein OS=Arabidopsis thaliana OX=3702 GN=At4g27480 PE=1 SV=1
11	Q9LR71	8.19e-19	92.4	447	0.108	0.208	Q9LR71_ARATH Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein OS=Arabidopsis thaliana OX=3702 GN=At1g03520 PE=1 SV=1
12	Q9LFQ0	2.10e-18	91.3	434	0.103	0.205	GT14B_ARATH Beta-glucuronosyltransferase GlcAT14B OS=Arabidopsis thaliana OX=3702 GN=GLCAT14B PE=2 SV=1
13	Q9FLD7	1.18e-17	89.0	447	0.091	0.177	GT14A_ARATH Beta-glucuronosyltransferase GlcAT14A OS=Arabidopsis thaliana OX=3702 GN=GLCAT14A PE=2 SV=1
14	Q9LE60	4.28e-17	87.0	424	0.106	0.217	Q9LE60_ARATH AT3g15350/K7L4_15 OS=Arabidopsis thaliana OX=3702 GN=At3g15350 PE=1 SV=1
15	Q8S8P3	2.32e-16	84.3	384	0.101	0.227	GT14C_ARATH Beta-glucuronosyltransferase GlcAT14C OS=Arabidopsis thaliana OX=3702 GN=GLCAT14C PE=2 SV=1
16	Q6T5E0	1.48e-15	82.0	400	0.094	0.203	Q6T5E0_RAT Glucosaminyl (N-acetyl) transferase 2 (I blood group) OS=Rattus norvegicus OX=10116 GN=Gcnt2 PE=4 SV=1
17	Q09324	2.60e-15	81.6	428	0.071	0.143	GCNT1_MOUSE Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase OS=Mus musculus OX=10090 GN=Gcnt1 PE=1 SV=2
18	P97402	3.64e-15	80.9	401	0.091	0.197	GCNT2_MOUSE N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase OS=Mus musculus OX=10090 GN=Gcnt2 PE=2 SV=2
19	Q9C9A1	3.77e-15	80.9	395	0.091	0.200	Q9C9A1_ARATH At1g71070/F23N20_6 OS=Arabidopsis thaliana OX=3702 GN=At1g71070 PE=1 SV=1
20	Q9P109	4.90e-15	80.9	453	0.094	0.179	GCNT4_HUMAN Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 OS=Homo sapiens OX=9606 GN=GCNT4 PE=2 SV=1

(a)	Ranking of proteins is based on the E-value of a BLASTp alignment.
(b)	ID1 and ID2 are sequence identities normalized by the query and template sequence lengths, respectively.

Pfam families

Top Pfam family matches

Rank	Pfam family	E-value	Score	Description
1	PF02485 Branch	4.1e-54	195.3	Core-2/I-Branching enzyme
2	PF12529 Xylo_C	7.4e-65	229.5	Xylosyltransferase C terminal

(a)	Ranking of Pfam families is based on the E-value provided by HMMsearch.

Protein-protein interaction (PPI) partners

Top PPI partners to 9606.ENSP00000017003

Rank	PPI partner	STRING score	Description
1	9606.ENSP00000029410	0.984	Beta-1,4-galactosyltransferase 7
2	9606.ENSP00000376345	0.960	Growth factor receptor-bound protein 2
3	9606.ENSP00000292377	0.931	Glypican-2
4	9606.ENSP00000307046	0.927	Syndecan-2
5	9606.ENSP00000366267	0.927	Glypican-5
6	9606.ENSP00000252575	0.924	Neurocan core protein
7	9606.ENSP00000363827	0.924	Basement membrane-specific heparan sulfate proteoglycan core protein
8	9606.ENSP00000359864	0.923	Glypican-4
9	9606.ENSP00000052754	0.922	Decorin
10	9606.ENSP00000327336	0.922	Biglycan
11	9606.ENSP00000264039	0.920	Glypican-1
12	9606.ENSP00000366246	0.919	Glypican-6
13	9606.ENSP00000377836	0.918	Glypican-3
14	9606.ENSP00000344468	0.916	Syndecan-3
15	9606.ENSP00000361818	0.916	Syndecan-4
16	9606.ENSP00000331210	0.914	Brevican core protein
17	9606.ENSP00000370542	0.913	Syndecan-1
18	9606.ENSP00000265077	0.908	Versican core protein
19	9606.ENSP00000312506	0.907	Chondroitin sulfate proteoglycan 4
20	9606.ENSP00000368678	0.907	Agrin

A higher STRING score indicates a greater likelihood of interaction.
The query and PPI partners are shown as grey oval and white rectangles, respectively.
Interactions between query and PPI partners are shown by solid black lines. Interactions among PPI partners are by dashed grey lines.
Values in the rectangles are the STRING scores between query and each corresponding PPI partner

Predicted Gene Ontology (GO) Terms

GO term	C-score	Name
GO:0030158	0.999	protein xylosyltransferase activity
GO:0005488	0.725	binding
GO:0005515	0.621	protein binding
GO:0016758	0.533	hexosyltransferase activity

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Molecular Function (MF) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0009987	0.998	cellular process
GO:0008152	0.997	metabolic process
GO:0071704	0.994	organic substance metabolic process
GO:0044238	0.991	primary metabolic process
GO:0044237	0.983	cellular metabolic process
GO:0006807	0.973	nitrogen compound metabolic process
GO:0006029	0.949	proteoglycan metabolic process
GO:0030166	0.939	proteoglycan biosynthetic process
GO:0044272	0.917	sulfur compound biosynthetic process
GO:0030203	0.901	glycosaminoglycan metabolic process
GO:0006024	0.420	glycosaminoglycan biosynthetic process

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Biological Process (BP) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

GO term	C-score	Name
GO:0005794	1.000	Golgi apparatus
GO:0031090	0.997	organelle membrane
GO:0005576	0.996	extracellular region
GO:0000139	0.987	Golgi membrane
GO:0005615	0.983	extracellular space

C-score is the confidence score of a predicted GO term. Its value ranges from (0,1], where a higher value indicates a higher confidence prediction.
If a child GO term and its parent term have the same C-score, only the child term is shown in this table.

The graph shows the predicted terms for the Cellular Component (CC) GO aspect. GO terms shown in the table are colored by C-score in the graph:

[0.3,0.4)

[0.4,0.5)

[0.5,0.6)

[0.6,0.7)

[0.7,0.8)

[0.8,0.9)

[0.9,1.0]

Predicted reactions (EC numbers and Rhea reactions)

Reaction	C-score	Name
RHEA:50192	0.999	L-seryl-[protein] + UDP-alpha-D-xylose = 3-O-(beta-D-xylosyl)-L-seryl-[protein] + H(+) + UDP
EC:2.4.2.26	0.999	protein xylosyltransferase.
EC:2.4.1.-	0.533	Hexosyltransferases.

[back to server]